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(4,741 - 4,760 of 10,083)
Pages
- Title
- Fire extinguishers for automobiles
- Creator
- Gielow, W. C, Hepp, E. J
- Date
- 2009, 1914
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/fireextinguisher00giel
Thesis (B.S.)--Armour Institute of Technology, 1914 B.S. in Fire Protection Engineering,...
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Thesis (B.S.)--Armour Institute of Technology, 1914 B.S. in Fire Protection Engineering, 1914
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- Title
- THE IMPACT OF THE JOINT POSTURE ON FINGER NEUROMECHANICS
- Creator
- Qiu, Dan
- Date
- 2014, 2014-05
- Description
-
This dissertation presents a series of studies investigating the neuromechanical properties of the index finger with special emphasis on how...
Show moreThis dissertation presents a series of studies investigating the neuromechanical properties of the index finger with special emphasis on how these properties varied with finger posture. A cadaver study was performed to measure the mapping relationship between tendon force and the resulting fingertip force. A strong linear relationship between magnitude of the tendon force and magnitude of the produced fingertip force was confirmed, up to the force levels examined. The finger posture, however, strongly influenced both fingertip force direction and magnitude. Two fundamental hypotheses of finger biomechanical modeling were then tested in further cadaveric studies. The preliminary results supported the assumption of linear superposition of the contributions of individual tendon forces to the overall fingertip force, at least for two muscles up to the force levels tested. It is also confirmed that the index finger force was almost exclusively produced by the muscles of the index finger, with relatively minor contributions from the other compartments of flexor digitorum superficialis (FDS), flexor digitorum profundus (FDP), or extensor digitorum communis (EDC). An in-vivo human subject study was performed to examine muscle activation patterns during isometric fingertip force production across task directions and finger postures. It was shown that significant changes in muscle excitation patterns occurred, especially with variations in interphalangeal (IP) posture. These changes involved fundamental variation in the underlying pattern rather than just scaling of a given activation pattern. An anatomically correct force-based computer model of the index finger was built to study the roles of different structures and characteristics in finger task performance. The model was validated with the cadaver study result to display its reliability in predicting fingertip xiii force and dynamic movement for given tendon forces. The model was then employed to estimate some hard-to-measure variables including joint contact force and joint passive torque components. The simulation of tendon injuries with the model, including Boutonniere deformation and mallet finger, was able to predict the abnormal finger joint movements under these patho-mechanical conditions. The model simulation also suggested that fingertip force capacity was largely maintained after selected tendon pulley excision surgeries.
PH.D in Biomedical Engineering, May 2014
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- Title
- Conversion tables for various viscosimeters using the Saybolt universal viscosimeter as the standard
- Creator
- Goodman, Harry M, Luttge, Harold
- Date
- 2009, 1917
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/conversiontables00good
Thesis (B.S.)--Armour Institute of Technology, 1917 Bibliography: leaf 54 B.S. in...
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Thesis (B.S.)--Armour Institute of Technology, 1917 Bibliography: leaf 54 B.S. in Mechanical Engineering, 1917
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- Title
- The composition and utilization of wood tar
- Creator
- James, Garrett B, Sieck, Herbert.
- Date
- 2009, 1911
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/compositionutili00jame
Thesis (B.S.)--Armour Institute of Technology, 1911 Bibliography: leaf 27 B.S. in...
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Thesis (B.S.)--Armour Institute of Technology, 1911 Bibliography: leaf 27 B.S. in Chemical Engineering, 1911
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- Title
- The construction and calibration of a new type of pressure gauge
- Creator
- Chan, Yoke H.
- Date
- 2009, 1911
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/constructioncali00chan
Thesis (B.S.)--Armour Institute of Technology, 1911 B.S. in Mechanical Engineering, 1911
- Title
- The design of a reinforced concrete brick plant capacity 60,000 to 80,000 brick daily
- Creator
- Kornfield, L. P, Garrison, C. W
- Date
- 2009, 1913
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofreinforc00korn
Thesis (B.S.)--Armour Institute of Technology, 1913 B.S. in Civil Engineering, 1913
- Title
- Design of reinforced concrete arch highway bridge
- Creator
- Duffy, Joseph L
- Date
- 2009, 1915
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofreinforc00duff
Thesis (B.S.)--Armour Institute of Technology
- Title
- Design of a reinforced concrete steel arch bridge
- Creator
- Dean, Stanley, Penn, J. C.
- Date
- 2009, 1905
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofreinforc00dean
Thesis (B.S.)--Armour Institute of Technology
- Title
- Design of proposed hydro-electric power plant on Big Salmon River, Idaho
- Creator
- Newhouse, Arthur M, Pettibone, Gerry D, Jones, Harvey W.
- Date
- 2009, 1911
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofproposed00newh
Thesis (B.S.)--Armour Institute of Technology, 1911 B.S. in Electrical Engineering, 1911
- Title
- The design of a reinforced concrete chimney
- Creator
- Burke, S. J.
- Date
- 2009, 1921
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofreinforc00burk
Thesis (B.S.)--Armour Institute of Technology
- Title
- Design of proposed hydro-electric power plant at Box Canyon, Idaho
- Creator
- Hager, E. A., Bangs, F. T
- Date
- 2009, 1913
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofproposed00hage
Thesis (B.S.)--Armour Institute of Technology, 1913 Bibliography: leaves 20-21 B.S. in...
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Thesis (B.S.)--Armour Institute of Technology, 1913 Bibliography: leaves 20-21 B.S. in Electrical Engineering, 1913
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- Title
- Design of a railroad viaduct for Overton County railroad
- Creator
- Scharle, L. M.
- Date
- 2009, 1907
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofrailroad00scha
Thesis (B.S.)--Armour Institute of Technology
- Title
- Design of a proposed hydro-electric development on the Desplaines River at Dresden Heights, Ill.
- Creator
- Curtis, Marston, Stansel, W. G., Meyer, Philip, Williams, R. D.
- Date
- 2009, 1913
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofproposed00curt
B.S. in Civil Engineering
- Title
- Design of a reinforced concrete railroad arch bridge
- Creator
- Allen, O. T., Holcomb, C. S.
- Date
- 2009, 1906
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/designofreinforc00alle
Thesis (B.S.)--Armour Institute of Technology
- Title
- The drossing of zinc in galvanizing pans
- Creator
- Whittington, J. A.
- Date
- 2009, 1919
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/drossingofzincin00whit
Thesis (B.S.)--Armour Institute of Technology; Bibliography: leaf 45
- Title
- MOLECULAR MECHANISMS OF ESTROGEN RECEPTOR BETA ACTION IN COLORECTAL CARCINOGENESIS
- Creator
- Vaz Saleiro, Diana Nora
- Date
- 2013, 2013-07
- Description
-
Colorectal cancer (CRC) is a major public health problem in the world population, which emphasizes the need to study novel molecular targets...
Show moreColorectal cancer (CRC) is a major public health problem in the world population, which emphasizes the need to study novel molecular targets in order to develop alternative chemopreventive and chemotherapeutic strategies against it. Estrogens have been shown to exert a protective role against CRC and its actions seem to be mediated by estrogen receptor β (ERβ). However, further studies are required to elucidate the role of ERβ in the colon. To achieve this goal, we evaluated the effects of ERβ deficiency in sporadic CRC and colitis-associated CRC (CAC) by using two in vivo models. In addition, we stably transfected RKO colon cancer cells to overexpress ERβ and identify novel molecules regulated by ERβ signaling in vitro. In the sporadic CRC in vivo model, azoxymethane (AOM)-treated ERβ knockout (βERKO) mice showed a significantly higher incidence and multiplicity of colonic preneoplastic lesions compared to AOM-treated ERα knockout and wild-type (WT) mice. These results were associated with a loss of normal colonic crypt organization and a decrease in apoptosis rates suggesting that ERβ is the ER subtype with a protective role against sporadic CRC progression. Confirming this hypothesis, we observed that AOM-treated βERKO mice presented a significantly higher incidence of adenomas than WT mice. By real time-polymerase chain reaction and immunohistochemistry analyses, ERβ-deficient adenomas were shown to be more proliferative and less differentiated than adenomas in WT mice. Furthermore, in the CAC in vivo model, βERKO mice developed more severe clinical colitis compared to WT mice, as evidenced by significantly higher disease activity index, weight to length ratio of the colons, inflammation score, and grade of dysplasia. ERβ-deficient tumors were characterized by a significant increase in pro-inflammatory xv molecules, suggesting that ERβ might exert anti-inflammatory effects in CAC. Moreover, in vitro results revealed a novel molecular mechanism by which ERβ might drive differentiation of goblet cells in the colonic epithelium. Altogether these findings highlight the importance of ERβ in protection against colorectal carcinogenesis and provide a clinical and translational potential to use ERβ selective agonists in order to prevent and/or treat CRC.
PH.D in Biology, July 2013
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- Title
- RESPONSE STYLE AS A MODERATOR BETWEEN COMBAT EXPOSURE AND PTSD SYMPTOMATOLOGY
- Creator
- Walton, Jessica
- Date
- 2011-11, 2011-12
- Description
-
Throughout the literature, combat exposure has been consistently linked to PTSD symptomatology among combat veterans. However, the wayan...
Show moreThroughout the literature, combat exposure has been consistently linked to PTSD symptomatology among combat veterans. However, the wayan individual responds to clinical interactions, also known as their response style, has received little or no attention as a potential moderating variable between combat exposure and PTSD symptomatology. Much of the research in the area of response style has utilized the MMPVMMPI-2 validity scores as a means to detect over-reporting among combat veterans. However, at present, few studies have examined responses on both the MMPI-2 validity scales and the SIRS as they relate to the detection of over-reporting on other measures (i.e., PCL-M and CES). The current study seeks to examine whether the response style on selected MMPI2 F-family validity scales and the SIRS among a sample of Vietnam combat veterans moderates the relationship between combat exposure and PTSD symptom endorsement. Individuals' combat exposure and current PTSD symptomatology were assessed through the use of self-report measures. In addition, participant's response style was assessed through the use of both the MMPI-2 and the Structured Interview of Reported Symptoms (SIRS). The results of the study demonstrated that response style did not moderate the relationship between combat exposure and PTSD symptomatology. However, results did reveal that individual's responses on the SIRS were directly related to PTSD symptom endorsement.
Ph.D. in Psychology, December 2011
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- Title
- CONTROLLED RELEASE OF VANCOMYCIN FROM A THERMORESPONSIVE HYDROGEL SYSTEM FOR THE PROPHYLACTIC TREATMENT OF POST-OPERATIVE ACUTE ENDOPHTHALMITIS
- Creator
- Dosmar, Emily
- Date
- 2017, 2017-05
- Description
-
Current clinical treatment for preventing the post-operative endophthalmitis include a bolus injection of the antibiotic, vancoymin (VAN),...
Show moreCurrent clinical treatment for preventing the post-operative endophthalmitis include a bolus injection of the antibiotic, vancoymin (VAN), during surgery followed by a 1-2-week period of patient administered, topically applied antibiotics. Due to poor patient compliance, drug loss due to poor drug residence time for topically applied drops, and limitations of drug injection sites, there is a clinical need for a subconjunctival, sustained release drug delivery system. While a controlled drug delivery system is beneficial by eliminating patient drug administration and improving drug delivery, the challenges of initial burst (IB), drug release kinetics, and drug distribution must be addressed in order to design an optimal system to address this need. The primary goal of this study was to develop a drug delivery system (DDS) capable of delivering VAN for 10-14 days and replacing both the bolus VAN injection and the topical eye drops. We hypothesized that controlled and extended release of VAN will perform equally or better than bolus VAN administration and eye drops. To accomplish this goal, three specific aims were performed: 1) Development of an injectable drug delivery system to release bioactive VAN for at least 10 days; 2) Validation of the efficacy of the developed DDS; and 3) Development of a compartmental model analysis model used to predict the loading dose required to achieve therapeutic drug concentration in the vitreous.
Ph.D. in Biomedical Engineering, May 2017
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- Title
- Distribution of water from open sprinklers on ridge poles
- Creator
- Evans, S. L., Mann, R. N., Marx, F. E.
- Date
- 2009, 1918
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/distributionofwa00evan
Thesis (B.S.)--Armour Institute of Technology
- Title
- Distribution of potential in suspension type insulators
- Creator
- Kallis, M., Ruede, E. M.
- Date
- 2009, 1910
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/distributionofpo00kall
Thesis (B.S.)--Armour Institute of Technology