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Title: ISOLATION OF MONOSPECIFIC ANTIBODY AGAINST SPLICED VARIANT OF DYSTROPHIN PROTEIN USING YEAST SURFACE DISPLAY TECHNIQUE
Creator: Saraswathi, Raj Prabu Vijayakumar
Date: 2011-05-04, 2011-05
Description: Dystrophin gene is the largest in the human genome with 79 exons covering greater than 0.1% of the total genome, located on the Xp21 locus of...
Show moreDystrophin gene is the largest in the human genome with 79 exons covering greater than 0.1% of the total genome, located on the Xp21 locus of the “X” chromosome resulting in a 427kDa protein, “Dystrophin”. Dystrophin is an important cytoskeletal protein which belongs to the β-Spectrin/α-actinin family of proteins. It comprises of an amino terminal domain, alpha helical coiled structure COOH domain, central rod region with 24 STRs and four proline rich hinge regions. It plays a vital role in localizing the Dystrophin glycoprotein complex (DGC) in the Sarcollema and is associated with the DGC in controlling the signaling events of certain proteins associated with DGC. The large size of the gene makes it more vulnerable to mutations resulting in partially functional or non-functional Dystrophin. The absence of Dystrophin results in disruption of sub sarcolemma-extracellular matrix linkage, loss of nitric oxide, progressive muscle weakening and muscle wasting leading to the death of patients typically before the end of their teenage. In certain cases alternatively spliced isoforms produce Dystrophin with reduced length yet stable and completely functionality. The main focus of this project was to select monospecific antibody against the more stable alternatively spliced variant D14 (15”16”) 17, which is functional and more stable compared to unspliced parent D14:17. The yeast surface display technique was used to effectively screen and select the yeast scFv clones containing the monospecific antibody against our target spliced variant D14 (15”16”) 17 protein and D2:3. The yeast scFv sub population was enriched by repeated MACS and FACS selection. Test colonies picked from the enriched scFv pool were confirmed via PCR and restriction digestion analysis. The scFv for the respective antigens were then sub cloned into pPnnl-9 secretion vector using YVH10 yeast cells via LiTRAFCO method. It was clear that by repeated MACS and FACS selection the scFv pool can be enriched and the yeast scFv clone sub population can be reduced to a significant level. The scFv sub cloned into Pnnl-9 secretion vector can be purified using affinity chromatography and the further affinity and avidity studies can be conducted.
M.S. in Biology, May 2011
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Title: Motion Track Studios (Semester Unknown) EnPRO 351: MTSEnPRO351FinalReportSp09
Creator: Arrowood, Renee, Caughell, Ty, Collier, Cedric, Cornelius, Joel, Esbensen, Kirsten, Forneris, Craig, Gurnani, Sweta, March, Paul, Perle, Collin, Vice, Evan
Date: 2009, 2009-05
Description: The objective for IPRO 351 is to evaluate the business opportunities for commercializing Motion Track Studios. We will do this by conducting...
Show moreThe objective for IPRO 351 is to evaluate the business opportunities for commercializing Motion Track Studios. We will do this by conducting research pertaining to primary competitors, the industry as a whole, consumers’ wants and needs, conducting competitive analysis. We will also be developing a working prototype; conducting and comparing observations of several trial runs; and drafting a business plan/final report, which will include feasibility analysis and recommended future steps. Included in (but not limited to) the business plan/final report will be: - Description of Motion Track studios - Market and industry data - Market strategy - Internal analysis - Competitive analysis - Findings as extracted from trial runs - Projections for income, sales, and cash flow - Analysis of different business models/selected business model - Final recommendations including suggested next steps
Deliverables
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Title: Video Transducer System with Magnetic Transducer Head Having Output Winding Means Resonant at a Mid Band Resonance Frequency
Creator: Camras, Marvin
Date: 2009-05-04, 1975-03-11
Description: A wideband transducer system including longitudinally recorded video, transversely recorded or multiplexed audio, channel shifting during...
Show moreA wideband transducer system including longitudinally recorded video, transversely recorded or multiplexed audio, channel shifting during blanking intervals, high frequency bias synchronized to audio carrier frequency or otherwise selected to avoid beat notes, head with plural windings switched to reduce inductance during recording and connected for wideband playback into an amplifier input with comparable or higher impedance than that of the winding.
Sponsorship: IIT Research Institute
United States Patent
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Title: Devices that Assist Blind & Visually-Impaired Individuals in Swimming and Other Exercise Activities (sequence unknown), IPRO 310 - Deliverables: IPRO 310 Brochure F09
Creator: Dykeman, Kimberly, Healton, Michaela, Lipman, Timothy, Ludwig, Ross, Park, Jay, Reilly, Jeffrey, Sarkar, Smita, Sirk, Phillip, Toro, Branden
Date: 2009-12
Description: The objective is to develop, test, and implement assistive technology with the community that promotes safety and improves independence of...
Show moreThe objective is to develop, test, and implement assistive technology with the community that promotes safety and improves independence of blind and visually impaired (BVI) swimmers.
Sponsorship: Chicago Lighthouse for the Blind & Visually-Impaired. Notre Dame University
Deliverables for IPRO 310:Devices that Assist Blind & Visually-Impaired Individuals in Swimming and Other Exercise Activities for the fall 2009 semester.
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Title: Harvesting _ Beneficial use of Condensate from Air Conditioning Systems IPRO346 Summer2011 Midterm Presentation

Title: Multivariable MPC system performance assessment, monitoring, and diagnosis
Creator: Schaffer, J., Cinar, A.
Date: 2004-03
Publisher: ELSEVIER SCI LTD
Description: This study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a...
Show moreThis study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a benchmark and monitor model predictive control performance on-line. A performance measure based on the ratio of historical and achieved performance is used for monitoring and a ratio of design and achieved performance is used for diagnosis. Performance monitoring and diagnosis of causes for poor performance are integrated. A real-time knowledge-based system is developed to supervise monitoring and diagnosis activities. Case studies with linear and nonlinear models of an evaporator illustrate the methodology and limitations of linearity assumptions.
Endnote format citation for DOI:10.1016/j.jprocont.2003.07.003
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Title: L2E ESTIMATOR FOR THE CATEGORICAL MODEL WITH ELASTIC NET PENALTY
Creator: Wang, Yuan
Date: 2017, 2017-07
Description: The logistic regression model is an important generalized linear model for the categorical data. The maximum likelihood estimation is mostly...
Show moreThe logistic regression model is an important generalized linear model for the categorical data. The maximum likelihood estimation is mostly used in estimating the parameters of the logistic regression model. However, the maximum likelihood estimation is very sensitive to outliers which will cause the inaccuracies of the fitted parameters and model selection in high-dimensional regression. Chi and Scott (2014) demonstrated by simulation that minimizing the integrated square error or L2 estimation (L2E) is a robust method to fit 2-class categorical models. They also showed that the L2E estimation method can select the right model even in the presence of many outliers in high dimensional scenarios. In my thesis, I extended the L2E estimation method from 2-class to 3-class based on the MM algorithm by Chi and Scott (2014). Then I demonstrated the properties above for 2-class categorical models are also applicable to 3-class ones.
M.S. in Applied Mathematics, July 2017
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Title: Environmental Wood Reclamation (Semester Unknown) EnPRO 350: Environmental Wood Reclamation EnPRO 350 Final Presentation Su08
Creator: Budzinski, Catherine, Canales, Hernan, Chunuwe, Felix, Farris, Tasha, Fontes De Faria, Gabriel, Heppel, Chris, Ihmoud, Sana, Lee, Melissa, Martin, Amy, Mitchell, Victor, Patel, Avni, Rivas, Karen, Valadez, Julia, Jessica, Workman, Herman, Herman
Date: 2008, 2008-07
Description: This is the first semester of EnPro 350. Although the title suggests wood reclamation via arts and crafts, we have decided to expand the focus...
Show moreThis is the first semester of EnPro 350. Although the title suggests wood reclamation via arts and crafts, we have decided to expand the focus to reclamation via urban wood and lumber. We would like to start a business that addresses a need in the market for convenient removal of dead or infested trees in an urban setting. This encompasses all trees not located in forests or tree groves, and includes those found in urban setting. Often, the expense to remove one’s trees from his property is a time-intensive, confusing, and expensive process. We have decided to provide the service of tree health assessment, removal, processing, lumber certification, and marketing through utilizing the concept of vertical integration. Mission Statement: "To Satisfy Our Customers by Providing High Quality Wood from Urban Forests while Creating a Positive Change in the Environment"
Deliverables
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Title: Inflatable Greenhouse (semester?), IPRO 344: Infaltable Greenhouse IPRO 334 Abstract Sp06
Creator: Cervantes, Heidi, Ferraro, Christie, Lucid, Shannon, Teefey, Aaron, Woods, Nathaniel, Bains, Jasmeet, Ching, Neal, Langman, Michael, Mccrory, Reuben, Valdez, Oscar, Wright Iii, James, Bilderback, Matthew, Choi, David, Larson, Jeffrey, Meyer, Chad, Wang, Xiang, Carroll, Daniel, Crandell, Daniel, Lim, Eungjum, Nedrud, Joshua, Wojcik, Michael
Date: 2006-05, 2006-05
Description: The purpose of the Inflatable Greenhouse IPRO was to design an air supported structure that was cheaper than the current greenhouse solution....
Show moreThe purpose of the Inflatable Greenhouse IPRO was to design an air supported structure that was cheaper than the current greenhouse solution. The structural support of current greenhouses creates shadows that prevent an even sunlight exposure for the plants. The other issues we investigated were the cost, size, thermal control, and pest control of current greenhouse designs. The majority of the cost for a traditional greenhouse goes towards the structural support therefore an air supported structure should be significantly cheaper. The basic greenhouse design is oriented towards human occupants and is subsequently quite large. If the greenhouse was instead designed to house the plants already in the ground, just for the months that they needed shelter to grow, the cut back in size would also greatly affect the cost. We also looked into the thermal qualities of greenhouses. The very nature of a greenhouse absorbs and traps the light and heat of the sun. Without a cooling system a greenhouse can overheat and harm the plants within it. The other problem we found with current greenhouses was the pest control solution. Most greenhouses use strong chemicals that require special training for use and safety. Even the “organic” solutions use natural chemicals in concentrations considered toxic. Our goal was to design a greenhouse that would address each of these issues with a cheap and practical solution.
Deliverables for IPRO 334: Inflatable Greenhouse for the Spring 2006 semester
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Title: HawkTour (semester?), IPRO 305
Creator: Murali, Rohit, An, Sangmin, Jastrzebski, Marcin, Jenyo, Olumayowa, Kodamanchili, Richard, Dixon, Dave, Charles, Jodel, Ilea, Nicu
Date: 2005-05, 2005-05
Description: The Spring 2005 IPRO 305 team will be continuing the efforts of ongoing research at IIT in the realm of Pervasive Computing. The team will be...
Show moreThe Spring 2005 IPRO 305 team will be continuing the efforts of ongoing research at IIT in the realm of Pervasive Computing. The team will be focusing on the challenge of integrating Pervasive Computing into a specific aspect of the IIT campus. The overall vision of the IPRO 305 team is to continue efforts to develop an application called HawkTour – a virtual Illinois Institute of Technology tour guide. HawkTour will provide a completely new approach to the campus tour at IIT. The application has been designed to run on Tablet PC’s or other devices with similar computing capabilities, and provides the user with general campus information while guiding the user around campus and maintaining complete awareness of the user’s current location and intent, thereby adapting the tour to the user’s own personal preferences. The objective for this semester’s team is to refine the application and come up with a new version with an optimized content database, a more sophisticated hardware interface, improve the mapping methodology, work on the user interface and scale of the application to simpler devices such as cell phones and personal digital assistants.
Sponsorship: ekahau
Deliverables for IPRO 305: HawkTour for the Spring 2005 semester
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Title: A Recyclables Business Model for IIT (Semester Unknown) EnPRO 352
Creator: Wright, Sarah, Fraser, Linnea, Kim, Joseph, Mccabe, Mary, Goduco, Mike, Ramirez, Hugo, Vega, Daniel, O’toole, Bill, Shin, Eddie, Cumar, Raghuveer
Date: 2010, 2010-12
Description: contain the employees necessary to run and maintain the multiple programs which will be controlled by the Student Recycling Business. This...
Show morecontain the employees necessary to run and maintain the multiple programs which will be controlled by the Student Recycling Business. This business will also be in charge of creating events which will help to get the students, staff and faculty of IIT more involved in the recycling process. For prolonged success, the marketing component of any business plan is possibly one of the most essential. Within a student-run business, the need for campus support is enough motivation to implement an effective marketing strategy to advertise the products and gain an appropriate reputation. In terms of recycling, to achieve desired results for a specific objective requires that the target audience is fully informed. Thus, an awareness campaign must be introduced before any expected business success is observed. As shown by the provided data, the large diversity on campus has and most likely will always remain a unique attribute of IIT. Not only do the ethnicity and gender size vary from one category to the next, but the large demographic range (age) that is not presented due to unattainable information is also a significant factor in target marketing. Having language barriers and large generational gaps makes it difficult to impose a single marketing strategy all over campus. A successful marketing plan will overcome these obstacles with ideas that integrate all backgrounds and avoid cultural seclusion.
Sponsorship: IIT
Deliverables
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Title: Dry Alkali Chlorotitanates and Method of Making the Same
Creator: Schossberger, Frederic V.
Date: 1958-10-21
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: The IIT Reality: Finding a Job (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Project Plan F06
Creator: Allen, David Charles, Campana, Julia, Carlton, Kyle, Dela Cruz, Miguel, Lenzen, Paul, Mims, Megan, Olmos, Oscar, Pham, Christian, Pula, Janusz, Roberts, Ben, Woods, Carolyn J.
Date: 2006-12, 2006-12
Description: This semester IPRO 333, Video Documentary – Getting a Job after Graduation, is aiming its effort to help Illinois Institute of Technology...
Show moreThis semester IPRO 333, Video Documentary – Getting a Job after Graduation, is aiming its effort to help Illinois Institute of Technology Students get better jobs after graduation. This continuation of an earlier IPRO will strive to produce a video that presents four different challenges to be completed in the job seeking process. Students will work together in four “challenge” teams as well as three technical teams to accomplish its objective.
Deliverables for IPRO 333: The IIT Reality - Finding a Job for the Fall 2006 semester
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Title: Monitoring Safety of Railway Tank Cars (Fall 1999) IPRO 013: Monitoring Safety of Railway Tank Cars IPRO013 Fall1999 Final Presentation
Creator: Gupta, Kapil, Zukauskas, Elena, Patel, Jayesh, Lin, Shan
Date: 1999, 1999-12
Description: Railroad tank cars are efficient vehicles for the transport of large quantities of liquid commodities in North America. These commodities...
Show moreRailroad tank cars are efficient vehicles for the transport of large quantities of liquid commodities in North America. These commodities include foodstuffs as well as a wide range of chemicals use in the process industries. Transport Canada and the U.S. Department of Transportation collaborate in the formulation of rules and regulations for the transportation of hazardous commodities. While the incidence of non-accident release (NARs) is very small there is nevertheless a further collaborative effort by shippers and car owners alike to reduce the incidence of NARs to zero. One approach in reducing NARs is to develop a means to identify small leaks immediately, while the vehicle is in transit. The IPRO team will identify and evaluate methods for detecting small leaks using car mounted sensors and alerting the shipper of the leak automatically form remote locations. This includes consideration of how to mount sensors and telemetry devices, log data, predict unacceptable trends and incidents, and report them in a timely, reliable and cost-effective fashion. The technologies involved in the development of such a system would include characterization of target chemicals, sensors and date transmission, mounting to the tank car, evaluation of the econ0omic viability of the concepts, and identification of potential legal implications.
Sponsorship: Union Tank Car Company
Project Plan for IPRO 013: Monitoring Safety of Railway Tank Cars for the Fall 1999 semester
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Title: Multivariate statistical methods for monitoring continuous processes: Assessment of discrimination power of disturbance models and diagnosis of multiple disturbances
Creator: Raich, A. C., Cinar, A.
Date: 1995-11
Publisher: ELSEVIER SCIENCE BV
Description: A new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine...
Show moreA new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine out-of-control status of a continuous process and to diagnose the source causes for abnormal behavior. Most of the disturbances were identified with good rates of success, with a higher success rate for step or ramp type of disturbances. Quantitative tools that evaluate overlap and similarity between high-dimensional PCA models are proposed in this communication, and their implications on determining the discrimination power of PCA models of processes operating under disturbances are discussed. Diagnosis of several disturbances occurring simultaneously is also investigated. The criterion developed provide upper limits of discrimination power of various single and multiple process disturbances. The techniques developed are illustrated by assessing the process described by the Tennessee Eastman Control Challenge problem [3].
Endnote format citation
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Title: Green Leaf Community (Semester Unknown) IPRO 357: GreenleafCommunity IPRO357PosterF10
Creator: Beck, Steve, Paschal, William, Snyder, Mark, Rueda, Jorge, Hegde, Namrata, Semenova, Svetlana, Xiao, Yao, Anglin, Christopher, Qaisar, Samir, Sung Shin, Woo, Yun, Joonggeun, Prokop, Samantha
Date: 2010, 2010-12
Description: Our purpose is to study the design of sustainable residential housing model designed by the Inter-professional group in the fall of 2009 and...
Show moreOur purpose is to study the design of sustainable residential housing model designed by the Inter-professional group in the fall of 2009 and determine the construction costs for the model. This along with the market analysis will set a baseline price for the average buyer of this home. Our goal is to redesign this model with the current economic market in mind and make this model of sustainable design marketable and economically feasible with use of more efficient designing and systems.
Deliverables
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Title: PARAMETRIC IMAGE ESTIMATION IN ANALYZER-BASED PHASE CONTRAST IMAGING
Creator: Caudevilla, Oriol
Date: 2014, 2014-07
Description: Since the discovery of X-rays, by W.E. Roentgen in 1895, absorption-contrast imaging has been widely used in medical diagnostic, for example:...
Show moreSince the discovery of X-rays, by W.E. Roentgen in 1895, absorption-contrast imaging has been widely used in medical diagnostic, for example: mammography, chest X-ray, angiography etc. Over the last 25 years many researchers have shown that phase-contrast X-ray imaging is capable of obtaining a better contrast then classical absorption-contrast imaging. This is especially true in soft tissue imaging like mammography or at higher Xrays energies. During the past five years a significant effort has made in development of a tabletop analyzer-based phase-contrast system. In this system a perfect crystal is used to generate a quasi-monochromatic beam, which after interacting with an object is analyzed by a second perfect crystal called analyzer. The need of quasi-monochromatic beam and the low brilliance of conventional X-ray sources (CXS) has been the major limiting factor for tabletop systems. The work presents in this thesis aims to develop novel reconstruction methods for tabletop analyzer-based phase-contrast imaging (ABI) systems. The presented reconstruction methods goal is to minimize the impact of CXS low brilliance by utilizing phase-contrast image formation model and maximum or maximum-a-posteriori Poisson likelihood approach. Finally, a fast-convergent conjugate gradient optimization algorithm has been derived specifically for Poisson likelihood function maximization.
M.S. in Electrical Engineering, July 2014
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Title: Magnetic Recorder and Reproducer for Video
Creator: Camras, Marvin
Date: 1959-08-18
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: Combating Underage Drinking and Driving (Semester Unknown) EnPRO 351: CombatingUnderageDrinkingandDrivingEnPRO351AbstractSp10
Creator: Burnett, Shana, Choi, Minsung, Garfinkle, Faye, Howe, Phaedra, Jin Kim, Hyo, Macon, Briana, Perez, Alicia, Salem, Stephanie
Date: 2010, 2010-05
Description: The purpose of IPRO 351 is to create a product that discourages minors driving under the influence of alcohol that will act as an unbiased...
Show moreThe purpose of IPRO 351 is to create a product that discourages minors driving under the influence of alcohol that will act as an unbiased mediator that takes the decision of driving drunk out of the driver‟s hands. Our goal is to determine the most efficient, cost effective means to achieve this and to obtain, through surveys and continued research, a possible market that would be interested in the design.
Deliverables
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Title: Conceptual Design and Planning for the Environment of Chicago Area Health Clinics by Access Community Health (Semester Unknown) IPRO 340: Design of a “Green” Community IPRO 340 Ethics F08
Creator: Bellamy, Ernest, Bo, Loren, Chung, Lawrence, Dipego, Danielle, Gala, Pankti, Glover, Crystal, Howe, Phaedra, Khanna, Omaditya, Park, Jongpil, Wahlstrom Helgren, Sarah, Yu, Mary, Ziswa, Sungano
Date: 2008, 2008-12
Description: In the 21st century, medical technology is advancing at a rapid rate, thus allowing people to benefit from new treatments being developed....
Show moreIn the 21st century, medical technology is advancing at a rapid rate, thus allowing people to benefit from new treatments being developed. However, much of the underserved and underinsured public are not benefiting from the breakthroughs as one might expect. In order for the existing facilities to better serve the public, gradual transformations and upgrades must be made. This is the challenge being tackled by our IPRO: How can we realistically suggest a renovation model for existing Access Community Health Network facilities which would promote cost efficiency and technological advancement in both environmental and operational capacities? - The primary objective of this session of IPRO 340 is to deliver a five-year model for which existing Access Community Healthcare facilities can be shaped into more environmentally and operationally efficient centers for medical treatment. - In designing such a model, secondary goals include familiarization with cutting edge medical technology, modernized building flow, spatial relations, as well as the development of business process models. In addition, we plan to investigate ways in which Access Community Healthcare can enhance the level of patient experience by making peoples’ visit to their facilities more enjoyable and informative.
Deliverables
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