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Title: DISRUPTION OF EPILEPTIC SEIZURES USING TARGETED MULTI-SITE ELECTRICAL STIMULATION
Creator: Sobayo, Tiwalade
Date: 2015, 2015-12
Description: Neuronal populations in the brain achieve levels of synchronous electrophysiological activity during both normal brain function and...
Show moreNeuronal populations in the brain achieve levels of synchronous electrophysiological activity during both normal brain function and pathological states such as epileptic seizures. Understanding how the dynamics of neuronal oscillators in the brain evolve from normal to diseased states is a critical component towards decoding such complex behaviors. In my studies, I assessed multi-site dynamics underlying seizure evolution in limbic epilepsy by analyzing oscillators in recordings of local field potentials from three brain structures (bilateral hippocampi and anteromedial thalamus) in a rat model of temporal lobe epilepsy extracted using the empirical mode decomposition (EMD) technique. The analysis revealed patterns of multi-site phase coherence during initiation and termination phases of seizures. The multi-site synchrony events as seizures naturally terminated were used to model electrical deep brain stimulation (DBS) protocols aimed at stopping ongoing epileptic seizures. The location and frequency of the natural termination synchrony varied between subjects but was stable in time within each animal. My studies reveal that DBS protocols were significantly more effective at rapidly stopping seizures when the frequency and location of multi-site stimulation reflected the endogenous synchrony dynamics observed in each subject. These results strongly suggest that tailoring DBS protocols to individual endogenous rhythms that may represent how brains naturally resolve epileptic seizures could play a critical role in vastly improving the overall efficacy of this important therapy.
Ph.D. in Biomedical Engineering, December 2015
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Title: High Performance Green Homes (sequence unknown), IPRO 317 - Deliverables: IPRO 317 Poster F09
Creator: Bhat, Adnan, Campbell, Brittanie, Cink, Jefferey, Gutstein, Yehuda, Hadi, Shuaib, Hafdi, Kamal, Hasan, Hasan, Kenig, Elezar, Lipski, Brian, Lollino, Luca, Margolis, Jordan, Nigamatzyanov, Tagir, Patel, Hiren, Patel, Neal, Shehada, Hazem, Toops, Melissa, Trauner, Crystal, Zgourdah, Mourad
Date: 2009-12
Description: The purpose of this project is to show how a team committed to helping people help save the world can leapfrog today's best designs. As...
Show moreThe purpose of this project is to show how a team committed to helping people help save the world can leapfrog today's best designs. As opposed to the tradition of minimum design standards that just meeting the building code, highest practical design standards are the focus. True sustainability is the goal of this project, including; Zero Carbon Emissions, Net Zero Energy, 100% Solar Power, 10 times the traditional design life, 1/10th the maintenance, rot proof, termite proof, fire proof, hurricane and earthquake resistant. The project team, using cutting edge technology, will develop all aspects of a start-up design and build company to promote High Performance Green Homes. This project will provide a great opportunity for IIT students to experience a challenging and interesting project and to significantly contribute to a better world.
Sponsorship: Jimmy Eng
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Title: Orthotics and Prosthetics in Latin America (sequence unknown), IPRO 309 - Deliverables: IPRO 309 Final Report F09
Creator: Ashley, Trevor, Claxton, Matt, Conover, Stephen, Gotanco, Francis, Mathai, Alexander, Nizich, Adam, Park, Yong, Quikr, Kerry, Ray, Monmayuri, Vasquez, Raul
Date: 2009-12
Description: The overall goal of our IPRO team is to create a program for delivering orthotics and prosthetics that is sustainable. This will be...
Show moreThe overall goal of our IPRO team is to create a program for delivering orthotics and prosthetics that is sustainable. This will be accomplished by improving the quality of the product by increasing availability of funding, improving cost effectiveness of prosthetics, and promoting awareness of treatment available.
Deliverables for IPRO 309: Orthotics and Prosthetics in Latin America for the fall 2009 semester.
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Title: Finding Uses for Alternative Fuels in Intermodal Transportation Hubs (sequence unknown), IPRO 307 - Deliverables: IPRO 307 Midterm Presentation F09
Creator: Balakirev, Konstantin, Beau‐luby, Ryan, Bouikidis, John, Cargill, Matthew, Dziuba, David, Kehoe, Matthew, Slonski, Bryan, Tesfaye, Melat, Wiese, Matthew, Wiseman, Christopher, Zook, Joel
Date: 2009-12
Description: Chicago, being the third largest freight hub in the world, needs an efficient movement of goods for the increasing freight shipments.
Sponsorsh...
Show moreChicago, being the third largest freight hub in the world, needs an efficient movement of goods for the increasing freight shipments.
Sponsorship: Mi-Jack
Deliverables for IPRO 307: Finding Uses for Alternative Fuels in Intermodal Transportation Hubs for the fall 2009 semester.
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Title: Innovative Mapping (sequence unknown), IPRO 303 - Deliverables: IPRO 303 Final Report F09
Creator: Komoroski, Aaron, Mora, Andres, Sarraf, Basel, Kemp, Brandon, Duong, Cindy, Woodward, Frank, Suwada, Jerry, Michael, Mark, Sinha, Piyush, Glover, Richard, Mandrekar, Urba
Date: 2009-12
Description: The team worked to target the majority of mobile device users and give them an outlet to report any changes, mistakes or developments that...
Show moreThe team worked to target the majority of mobile device users and give them an outlet to report any changes, mistakes or developments that have been overlooked by NAVTEQ in the company's mobile mapping solutions. The team also worked to develop a solution that enables the average map user – men and women ages 18-35, students and tourists – to address these alterations in a simple, hassle-free way.
Sponsorship: NAVTEQ
Deliverables for IPRO 303: Innovative Mapping for the fall 2009 semester.
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Title: Rehabilitation of "Kumbharwada", Dharavi Slums, Mumbai
Creator: Purandare, Bhakti
Date: 2010-05-01, 2010-05-01
Description: Within the slums of India small and unventilated dwellings serve as multipurpose spaces where a families live as well as manufactures pottery...
Show moreWithin the slums of India small and unventilated dwellings serve as multipurpose spaces where a families live as well as manufactures pottery products. In terms of production mechanisms, potter’s depend on conventional kilns which are shared between families. They use cotton dust, rags /wastes and diesel & oil soaked cotton as firing fuel which is serious cause of population & health hazards.
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Title: Devices that Assist Blind & Visually-Impaired Individuals in Swimming and Other Exercise Activities (sequence unknown), IPRO 310 - Deliverables: IPRO 310 Brochure F09
Creator: Dykeman, Kimberly, Healton, Michaela, Lipman, Timothy, Ludwig, Ross, Park, Jay, Reilly, Jeffrey, Sarkar, Smita, Sirk, Phillip, Toro, Branden
Date: 2009-12
Description: The objective is to develop, test, and implement assistive technology with the community that promotes safety and improves independence of...
Show moreThe objective is to develop, test, and implement assistive technology with the community that promotes safety and improves independence of blind and visually impaired (BVI) swimmers.
Sponsorship: Chicago Lighthouse for the Blind & Visually-Impaired. Notre Dame University
Deliverables for IPRO 310:Devices that Assist Blind & Visually-Impaired Individuals in Swimming and Other Exercise Activities for the fall 2009 semester.
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Title: Multivariable MPC system performance assessment, monitoring, and diagnosis
Creator: Schaffer, J., Cinar, A.
Date: 2004-03
Publisher: ELSEVIER SCI LTD
Description: This study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a...
Show moreThis study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a benchmark and monitor model predictive control performance on-line. A performance measure based on the ratio of historical and achieved performance is used for monitoring and a ratio of design and achieved performance is used for diagnosis. Performance monitoring and diagnosis of causes for poor performance are integrated. A real-time knowledge-based system is developed to supervise monitoring and diagnosis activities. Case studies with linear and nonlinear models of an evaporator illustrate the methodology and limitations of linearity assumptions.
Endnote format citation for DOI:10.1016/j.jprocont.2003.07.003
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Title: Multivariate statistical methods for monitoring continuous processes: Assessment of discrimination power of disturbance models and diagnosis of multiple disturbances
Creator: Raich, A. C., Cinar, A.
Date: 1995-11
Publisher: ELSEVIER SCIENCE BV
Description: A new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine...
Show moreA new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine out-of-control status of a continuous process and to diagnose the source causes for abnormal behavior. Most of the disturbances were identified with good rates of success, with a higher success rate for step or ramp type of disturbances. Quantitative tools that evaluate overlap and similarity between high-dimensional PCA models are proposed in this communication, and their implications on determining the discrimination power of PCA models of processes operating under disturbances are discussed. Diagnosis of several disturbances occurring simultaneously is also investigated. The criterion developed provide upper limits of discrimination power of various single and multiple process disturbances. The techniques developed are illustrated by assessing the process described by the Tennessee Eastman Control Challenge problem [3].
Endnote format citation
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Title: NEUTRON PRODUCTION IN THE M2 MUON BEAM LINE AT CERN
Creator: Draeger, Emily
Date: 2014, 2014-05
Description: Spallation neutrons produced from cosmic ray muons are a major source of backgrounds in underground physics experiments. Experiments have been...
Show moreSpallation neutrons produced from cosmic ray muons are a major source of backgrounds in underground physics experiments. Experiments have been done to study spallation neutron production and yield, but our understanding of these processes is still limited. There are various interactions that can produce spallation neutrons. Most of these production mechanisms are fairly well understood; much of the uncertainty in our understanding of spallation neutrons lies in mechanisms such as virtual photon exchange and the assumptions used to calculate the photonuclear cross section. Even the experiments that have been carried out do not agree with each other or theoretical calculations. Spallation neutron production mechanisms are discussed, as well as a new experiment to study spallation neutrons. The impact of this study on current and future underground physics experiments is also explored.
PH.D in Physics, May 2014
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Title: INTELLIGENT PROCESS-CONTROL WITH SUPERVISORY KNOWLEDGE-BASED SYSTEMS
Creator: Kendra, S. J., Basila, M. R., Cinar, A.
Date: 1994-06
Description: The integration of a supervisory knowledge-based system (KBS) with a multivariable control system is examined to provide robust multivariable...
Show moreThe integration of a supervisory knowledge-based system (KBS) with a multivariable control system is examined to provide robust multivariable control of a chemical reaction process. The supervisory KBS is capable of monitoring the process to detect system faults as well as assessing control system performance. If a control system performance deficiency is detected, the KBS formulates and implements the necessary corrective controller tuning. This adaptive capability reduces the conservatism of the robust control system. The underlying mechanisms are discussed and the re-tuning ability of the KBS is illustrated by using rigorous simulations of a chemical reaction process
Endnote format citation
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Title: Planning the 21st Century Urban Farm: From High Rise to Neighborhood (sequence unknown), IPRO 336 - Deliverables: IPRO 336 Final Report F09
Creator: Bhatti, Talha, Binet, Adrien, Bredau, Jason, Chen, Emily, Davis, Jacob, Gaonkar, Gaurav, Garcia, Raul, Guerrero, Fernando, Gulling, Richard, Kagehiro, Michael, Moshfeghian, Elnaz, Nunez-gimeno, Jose, Phillips, Zachary, Plumb, Isaac, Ryan, Emily, Skaggs, Jake, Sobon, Konrad, Valmores, Travis
Date: 2009-12
Description: The purpose of this IPRO is to establish a strong foundation for the future of urban agriculture. The growing problems regarding the...
Show moreThe purpose of this IPRO is to establish a strong foundation for the future of urban agriculture. The growing problems regarding the traditional methods of agriculture, and the rate of growth of the world population, the team plans to design a method to grow food more efficiently and economically in urban areas. The team is looking at large, industrial warehouse-type buildings that have outlived their primary use, and creating a plan that utilizes these buildings to grow enough food for the surrounding communities.
Sponsorship: John Edel of Bubbly Dynamics, LLC
Deliverables for IPRO 336: Planning the 21st Century Urban Farm: From High Rise to Neighborhood for the fall 2009 semester
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Title: Planning for Human Implantation of a Cortical Visual Prosthesis (sequence unknown), IPRO 334 - Deliverables
Creator: Bern, David, Chen, Shanyl, Deroo, Mary, Gorski, David, Kelly, Thomas, Leasenby, Alex, Li, Zhi, Pyrkh, Hanna, Subhani, Maham, Taneja, Aanchal
Date: 2009-12
Description: The Intracortical Visual Prosthesis is based upon that concept that by implanting a large number of subminiature electrodes within the human...
Show moreThe Intracortical Visual Prosthesis is based upon that concept that by implanting a large number of subminiature electrodes within the human visual cortex, coordinated temporal-spatial image information can be artificially communicated to the human visual cortex in the form of electrical currents, acting as a sensory substitute for normal vision.
Sponsorship: IIT Laboratory of Neural Prosthetic Research
Deliverables for IPRO 334: Planning for Human Implantation of a Cortical Visual Prosthesis for the fall 2009 semester
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Title: NOVEL FAULT DIAGNOSTIC TECHNIQUE AND UNIVERSAL SENSOR FOR PERMANENT MAGNET ELECTRIC MACHINES USING SEARCH COILS
Creator: Da, Yao
Date: 2012-04-23, 2012-05
Description: Over the past decade, permanent magnet synchronous machines (PMSMs) have gained significant popularity in industry, such as wind turbines and...
Show moreOver the past decade, permanent magnet synchronous machines (PMSMs) have gained significant popularity in industry, such as wind turbines and electric vehicles, owing to their high efficiency, high output power to volume ratio, and high torque to current ratio. In these mission critical applications, an unexpected fault or failure of the machine could lead to very high repair or replacement cost, or even catastrophic system failure. Therefore a robust and reliable health monitoring and fault diagnostic approach is desired, which could help in scheduling preventive maintenance to lengthen their lifespan and avoid machine failure. This dissertation presents a novel multi-faults diagnostic approach using search coils. These search coils are wound around armature teeth, so they typically need to be installed during manufacturing. But its immunity to high frequency harmonics makes it suitable for inverter/rectifier fed motors or generators, such as wind turbines and automotive systems. In addition, this method does not require the knowledge of proprietary constructional details of the machine. Since the electromagnetic flux is directly measured in this method, it provides much more information than any other scheme: the direction of eccentricity and the location of shorted windings. Furthermore, this method is also capable of evaluating the severity of each fault, which is of significant importance in mission critical applications such as automotive, aerospace and military applications. In addition to these uses, the search coils can be used as a universal sensor to estimate phase current or rotor position, which are critical information in a PMSM close-loop control, which allow it to work as a backup sensor for fault tolerant operation. The proposed fault detection scheme and universal sensor concept have been tested under several scenarios with Finite Element Analysis and experimentally validated.
Ph.D. in Electrical Engineering, May 2012
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Title: CELL-MATRIX INTERACTIONS IN ADIPOSE TISSUE FUNCTION
Creator: Vaicik, Marcella K.
Date: 2015, 2015-07
Description: The overall goal of this work is to apply in vivo and in vitro models to study the basement membrane protein laminin α4 (lama4) in adipocyte...
Show moreThe overall goal of this work is to apply in vivo and in vitro models to study the basement membrane protein laminin α4 (lama4) in adipocyte function. Adipose tissue accumulation, lipogenesis, and structure were examined in mice with a null mutation of the lama4 gene (Lama4−/−) and compared to wild-type animals (Lama4+/+). The Lama4−/−mice phenotype was investigated to evaluate if the differences were due specifically to the adipose tissue function. Physical activity and food intake does not differ between Lama4+/+ and Lama4−/− mice. However, Lama4−/− mice have a significantly increased metabolic rate at 25°C and 16°C compared to Lama4+/+ mice. In contrast, in thermoneutral conditions at 30°C both Lama4+/+ and Lama4−/− mice exhibit equivalent metabolic rates. Interestingly, when room temperature housed mice fat pads were evaluated with immunohistochemistry, Lama4−/− mice exhibit significantly increased UCP-1 expression in subcutaneous adipose. These results suggest that beiging, white to brown adipocytes, in subcutaneous adipose tissue in Lama4−/− mice may lead to decreased adipose tissue accumulation and improved metabolic function. While animal models indicate the absence of lama4 results in more beiging in subcutaneous adipose tissue, an in vitro tissue engineered model was developed to study the adipocyte function in a controlled microenvironment. Primary cell spheroids developed from Lama4+/+ and Lama4−/− were incorporated into synthetic poly(ethylene glycol) (PEG) hydrogels within a range of stiffnesses. When the cells were given the same chemical cues their functions differed depending upon microenvironment stiffness. Beige function in adipocyte cells in 3D can be influenced by matrix stiffness. In conclusion, the laminin alpha 4 basement membrane protein absence in adipose tissue results in adipocyte functional changes in vivo. The Lama4−/− mice have resistance to diet induced weight gain and increased metabolic rate at room temperature and when cold challenged. The Lama4−/− mice had increased beiging in the subcutaneous depot. Additionally, a tissue engineered model was developed to further study cell-ECM interactions first identified in an animal model. These in vivo findings and the engineered model of adipose tissue have great potential for studying obesity and other adipose related diseases. Future work will require continued interdisciplinary collaboration towards the successful identification and screening of novel therapeutics using engineered tissue models.
Ph.D. in Biomedical Engineering, July 2015
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Title: Financial Incubators, India: panel copy
Creator: Shah, Shruti
Date: 2010-05-01, 2010-05

Title: Developing Web Applications for the Northern Illinois Hockey League (sequence unknown), IPRO 308 - Deliverables: IPRO 308 Midterm Presentation F09
Creator: Lucchesi, Kristin, Barksdale, Dustin, Hays, Julian, Bartus, Kryzystof, Perkins, William, Savage, Christopher, Scheer, Colin, Semenov, Vladimir, Vidutis, Mantas
Date: 2009-12
Description: The NIHL is the largest hockey league in Illinois. It is also the largest youth all star hockey league in the US, serving over 300 youth teams...
Show moreThe NIHL is the largest hockey league in Illinois. It is also the largest youth all star hockey league in the US, serving over 300 youth teams and over 4,000 players. The team's purpose is to make the NIHL a web-based scheduling and scoring applications that can support their annual operations.
Sponsorship: Northern Illinois Hockey League(NIHL)
Deliverables for IPRO 308: Developing Web Applications for the Northern Illinois Hockey League for the fall 2009 semester
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Title: BOUNDING ESTIMATION INTEGRITY RISK FOR LINEAR SYSTEMS WITH STRUCTURED STOCHASTIC MODELING UNCERTAINTY
Creator: Langel, Steven Edward
Date: 2014, 2014-05
Description: Safety critical estimation applications require quantification of integrity risk, which is the probability of the state estimate error...
Show moreSafety critical estimation applications require quantification of integrity risk, which is the probability of the state estimate error exceeding predefined bounds of acceptability. Integrity risk can only be evaluated when the state estimate error probability density function is precisely known, necessitating stochastic models that exactly describe measurement noise and disturbance inputs. Uncertainty in these models directly results in inaccurate assessments of integrity risk. This dissertation develops the first implementable methods to upper bound integrity risk when the autocorrelation functions of stochastic inputs reside between upper and lower bounding functions. The first part of this work considers real-valued estimation applications that use the Kalman filter or batch weighted least squares estimator. Explicit relations are developed between the estimate error variance and autocorrelation functions using a new generalized covariance matrix derived in this dissertation. From these expressions, two methods are provided to upper bound integrity risk. The first method enables fast computation of a conservative bound, and the second method produces the minimum upper bound via semi-definite optimization. Mixed real/integer estimation applications utilizing integer bootstrapping are the focus of the second part of this work. The integrity risk bound is formally defined as the global solution to a non-convex optimization problem over a polytope. Determination of the polytopic region is difficult, and two bounding approaches are initially developed for a circumscribing hyper-rectangular feasible region. Using an innovative method to define the polytope together with linear programming, a third method is derived to upper bound integrity risk over the true polytopic feasible region.
PH.D in Mechanical and Aerospace Engineering, May 2014
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Title: PA 508 Student Computer Usage Survey: PA508 Student Survey 2010 Results
Creator: Ahrens, Aric G.
Date: 2010-01-19, 2010-01-19
Description: Included are a survey, and the results in graphic form. The survey was designed to find out how and where the Chinese contingent of Master of...
Show moreIncluded are a survey, and the results in graphic form. The survey was designed to find out how and where the Chinese contingent of Master of Public Administration students used computers. The focus was to determine whether they preferred to use computers on the Downtown Campus, where classes were taught, or on Main Campus, where most of the students lived.
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Title: Teacher Knowledge Share (Semester Unknown) IPRO 320: Teacher Knowledge Share IPRO 320 MidTerm Presentation F08
Creator: Bern, David, Bochantin, Marike, Hartline, Julian, Mccall, Ian, Mick, Emily, Peake, Andrew, Pierce, Alison, Pindrik, Dmitriy, Quinn, Michael, Stanford, Carly, Tilatti, Michael
Date: 2008, 2008-12
Description: The goal of IPRO 320 is to create an online professional network for school teachers at the kindergarten through twelfth grade level to allow...
Show moreThe goal of IPRO 320 is to create an online professional network for school teachers at the kindergarten through twelfth grade level to allow for the sharing of ideas, lesson plans and other professionally relevant information. This is a continuing project which saw limited success in the previous semester in that a functioning web site was constructed based on surveys of public school teachers but it saw very little use. This semester, the planned approach is to build on the research generated last semester by performing additional market research with teachers. Following that, IPRO 320 will rework much of the previous web site by refining some of the features, adding additional ones as the research indicates and improving the website in general, both functionally and aesthetically.
Deliverables
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