Search results
(3,921 - 3,940 of 4,297)
Pages
- Title
- Linear Systems Analysis of Molecular Dynamics
- Creator
- Nicholson, Stanley Anselm
- Date
- 2023
- Description
-
Most proteins reduce the complexity of atomic motion to stable and coherent structures. Molecular dynamics (MD) has provided swaths of...
Show moreMost proteins reduce the complexity of atomic motion to stable and coherent structures. Molecular dynamics (MD) has provided swaths of trajectory data of proteins. We analyze these trajectories using classical stochastic signal analysis, well established and utilized by engineers. Linear systems analysis operates to uncover linearities given an input and output signal. The coherence function says an input and output are linearly related if and only if the coherence equals one. Analyzing protein motion in the frequency domain allows us to extract a frequency function relating the modes of motion as determined by atomic power spectra. Motivated by biochemistry, we analyze classical interactions like hydrogen bonds and salt bridges and find they act like a linear system, or effective spring. We test our analysis on two protein systems: crambin and the Mu Opioid Receptor (MOR). We extend our results to all pairwise interaction and determine coherent communities of atoms within the MOR. We present various community detection algorithms and demonstrate their validity using common metrics in MD. Identifying rigid and tightly correlated regions of the protein offers great potential in coarse graining protein structure and understanding protein motion.
Show less
- Title
- A Novel Explainability Approach For Spectrum Measurement Insight
- Creator
- Nagpure, Vaishali
- Date
- 2023
- Description
-
Spectrum is an extremely valuable natural resource in high demand. Although the spectrum has been fully allocated, there is no comprehensive...
Show moreSpectrum is an extremely valuable natural resource in high demand. Although the spectrum has been fully allocated, there is no comprehensive method for understanding about how it’s being used. Spectrum measurements are highly complex spatiotemporal data sets that play a key role in understanding spectrum use and require very specialized domain information for understanding. To leverage existing and future spectrum measurements to the fullest extent, it is necessary to have a systematic way to connect them to the contextual information that helps provide meaning to the data. To analyze and interpret the measurements, a variety of contextual information is needed. This research develops a novel approach for spectrum measurement understanding that unifies five years of wideband spectrum measurement summary data together with relevant contextual information from a variety of sources in a spectrum knowledge graph. Both quantitative and qualitative information is modeled and implemented on a Neo4j graph database platform. This modeling formalizes the relationships that help spectrum stakeholders “connect the dots” and provide deeper understanding of RF spectrum utilization. The knowledge graph can be queried to extract a wide variety of insights thus making spectrum knowledge more widely accessible to a variety of stakeholders.
Show less
- Title
- Pain and Life Satisfaction: The Role of Emotional Support and Social Participation in Adults with Pediatric-Onset Spinal Cord Injury
- Creator
- Oh, Alison J.
- Date
- 2023
- Description
-
Individuals who acquire a spinal cord injury (SCI) during their pediatric years are unique from individuals who acquire an SCI during...
Show moreIndividuals who acquire a spinal cord injury (SCI) during their pediatric years are unique from individuals who acquire an SCI during adulthood due to the heightened risks for developing secondary health conditions and chronic pain. These concerns may significantly impede developmental milestones and experiences, such as social participation, that may decrease life satisfaction. Thus, research on pain characteristics (e.g., frequency of pain, duration of pain, level of current pain, and level of general pain) alongside the role of emotional support and social participation on life satisfaction in adults with pediatric-onset SCI is needed. This study sample consisted of 205 individuals with pediatric-onset SCI who were former patients at pediatric hospitals in three metropolitan cities. Participants were individuals who were 19 years of age or older at the time of the interview, with the age of injury at 18 years or prior. Associations between demographic, pain, and injury characteristics, emotional support, social participation, and life satisfaction were assessed via bivariate Pearson correlations and a 3-block hierarchical multiple linear regression with LS as the primary outcome. Although pain characteristics and emotional support were not associated with life satisfaction among adults who sustained a pediatric-onset SCI, social participation was positively associated with life satisfaction. These findings suggest that clinicians should evaluate various pain characteristics and highlight the role of social participation when treating individuals with SCI.
Show less
- Title
- Examination of Power Ultrasound and Organic Acid-based Hurdle Technology in the Reduction of Salmonella Enterica on Peaches and Apples
- Creator
- Mathias, Hina Valida
- Date
- 2023
- Description
-
Fresh produce includes fruit matrices like whole peaches and apples that are minimally processed and are a popular choice among different...
Show moreFresh produce includes fruit matrices like whole peaches and apples that are minimally processed and are a popular choice among different types of demographics because of their nutrition content and health benefits. However, there have been increasing pathogen outbreaks in these matrices over the past few decades, which are majorly rooted in cross contamination either due to poor handling pre and post processing or the insufficient reduction of the pathogen at processing by the applied hurdle technology. While chemical sanitizers are a popular option in the food industry, the awareness and demand for green consumerism and sustainability have created a need for research to determine the efficacies of organic acids and non-thermal technologies like power ultrasound in the reduction of different pathogens on different food matrices. This study focusses on the S. enterica reduction capabilities of three organic acids – citric, malic, and lactic alone and in combination with 40 kHz power ultrasound at 1, 2 and 5% for treatment times of 2, 5 and 10 min on whole yellow peaches and gala apples. Peaches and apples were spot inoculated with a four-strain cocktail of S. enterica, resulting in 9 log CFU/fruit. Post air drying for 1 h, the fruits were treated with water, 1, 2, or 5% citric, lactic, or malic acid for 2, 5 or 10 min with and without power ultrasound treatment at 40 kHz. The population of S. enterica on the fruits was enumerated before and after treatment. Three independent trials with triplicate samples were performed for each condition. Population differences were evaluated via Student's t-test and ANOVA; p<0.05 was considered significant. The initial level of inoculum ranged from 8.67 ± 0.41 to 8.20 ± 0.26 log CFU/peach and 7.28 ± 0.60 to 8.17 ± 0.37 log CFU/apple in peaches and apples, respectively. Water treatments showed pathogen reduction as high as 1.22 log CFU/peach and 1.02 log CFU/apple. Citric acid treatments on peaches showed significant pathogen reduction at higher time increments at 5% with a reduction of S. enterica as high as 2.24 log CFU/peach after 10 min. Malic acid showed the highest recorded log reduction in peaches at 5% and 10 min being 4.20 log CFU/peach (n=1/9, samples above the enumeration limit) and apples at 5% and 5 min being 3.71 log CFU/apple (n=4/9, samples above the enumeration limit) both in combination with an ultrasound. Lactic acid, unlike the other two organic acids, showed a pathogen reduction of over 3 log CFU/fruit at 2% after 10 min, with the highest pathogen reductions of 3.76 log CFU/peach and >3.62 log CFU/apple at 5% and10 min. There was no particular trend with significant enhancement of pathogen reduction either with time increment or the addition of ultrasound and varied with the varying acids, treatment conditions and fruit matrices.
Show less
- Title
- Cities on the Move: Envisioning Cityscape in the Autonomous Vehicle Era
- Creator
- Lee, Hyo Eun
- Date
- 2023
- Description
-
As cities have developed in response to a rapidly changing environment since the industrial revolution, a variety of circumstances and issues...
Show moreAs cities have developed in response to a rapidly changing environment since the industrial revolution, a variety of circumstances and issues have arisen. In cities, technological development and the rise of private automobiles have been related to urban sprawl, traffic congestion, environmental degradation, and mobility inequalities. Currently, autonomous vehicles are bringing a paradigm shift in mobility as technological innovations accompany the fourth industrial revolution. As cities undergo renewal through new mobility, recent developments in driverless technologies should be considered for their long-term impact on the built environment. The purpose of this thesis is to propose a design, along with a set of scenarios, for a transportation hub in the era of autonomous vehicles to address today's complex mobility requirements. Through bringing together existing case studies, research on autonomous vehicles, and drawing conclusions regarding the relationship between mobility and urban landscapes, this thesis explores how autonomous vehicles will affect the future built environment in a set of timelines. Considering the future transportation hub will require programs and infrastructure to support autonomous vehicles, this thesis also provides a vision of the future of transportation modes and how they interact. Finally, a transportation hub design model and an automation city model for the AV era will be proposed.
Show less
- Title
- Krastof, Mark, Oral History Interview, 2011
- Creator
- Krastof, Mark, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Mark Krastof, who received an MS in Design from the Institute of Design in 1971. Krastof recounts his experience as a...
Show moreVideo interview with Mark Krastof, who received an MS in Design from the Institute of Design in 1971. Krastof recounts his experience as a student under Arthur Siegel, Aaron Siskind, and Garry Winogrand. Krastof shows copies of his photographs. Running time is 15:13 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Grimes, John, Oral History Interview, 2011
- Creator
- Grimes, John, 1945-, Walker, Dale, Kuruna, Daniel
- Date
- 2011-06
- Description
-
Video interview with John Grimes, who received an MS in Design from the Institute of Design (ID) in 1974. Grimes recounts his experiences as a...
Show moreVideo interview with John Grimes, who received an MS in Design from the Institute of Design (ID) in 1974. Grimes recounts his experiences as a student under Arthur Siegel and Garry Winogrand (adjunct faculty in 1972), as well as his time as an ID faculty member and acting director in the late 1970s. Also addressed is the history of photography at ID and photographic education in general. Running time is 1:17:39 minutes. This interview was conducted c. June 2011 in John Grimes' home office in Chesterton, Indiana.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Bulucos, Don, Oral History Interview, 2011
- Creator
- Bulucos, Don, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Don Bulucos, who received an MS in Design from the Institute of Design in 1967. Bulucos recounts his experience as a...
Show moreVideo interview with Don Bulucos, who received an MS in Design from the Institute of Design in 1967. Bulucos recounts his experience as a student under Harry Callahan, Aaron Siskind, and Kenneth Josephson. Running time is 18:09 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Hansen, Glenn, Oral History Interview, 2011
- Creator
- Hansen, Glenn, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Glenn Hansen, who received his MS in Photography/Design from the Institute of Design in 1984. Running time is 7:11 minutes.
- Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Hocker, Thomas, Oral History Interview, 2011
- Creator
- Hocker, Thomas, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Thomas Hocker, who received an MS in Design from the Institute of Design in 1969. Running time is 5:42 minutes.
- Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Krejci, Donald, Oral History Interview, 2011
- Creator
- Krejci, Donald, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Donald Krejci, who received an MS in Design from the Institute of Design in 1974. Krejci recounts his experience as a...
Show moreVideo interview with Donald Krejci, who received an MS in Design from the Institute of Design in 1974. Krejci recounts his experience as a student under Arthur Siegel and the details of his master's thesis. Running time is 5:59 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Kostiner, Lewis, Oral History Interview, 2011
- Creator
- Kostiner, Lewis S., 1950-, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Lewis Kostiner, who received an MS in Design from the Institute of Design in 1974. Kostiner recounts his experiences as...
Show moreVideo interview with Lewis Kostiner, who received an MS in Design from the Institute of Design in 1974. Kostiner recounts his experiences as an undergraduate student at the Rhode Island School of Design under Harry Callahan and Aaron Siskind, as well as at ID as a graduate student under Arthur Siegel. Running time is 13:12 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Sterling, Deborah Oral History Interview, 2011
- Date
- 2011-05-01
- Description
-
Video interview with Deborah Sterling, speaking on behalf of her deceased husband Joseph Sterling, who received his MS in Design from the...
Show moreVideo interview with Deborah Sterling, speaking on behalf of her deceased husband Joseph Sterling, who received his MS in Design from the Institute of Design in 1962. Running time is 7:36 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Josephson, Kenneth, Oral History Interview, 2011
- Creator
- Josephson, Kenneth, 1932-, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Kenneth Josephson, who received an MS in Design from the Institute of Design in 1960. Josephson recounts his experience...
Show moreVideo interview with Kenneth Josephson, who received an MS in Design from the Institute of Design in 1960. Josephson recounts his experience as a student under Harry Callahan, Aaron Siskind, and Art Sinsabaugh, as well as an ID faculty member in the mid 1960s. Running time is 19:27 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Mosher, Robert, Oral History Interview, 2011
- Creator
- Mosher, Robert, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Robert (Bob) Mosher, who received an MS in Design from the Institute of Design in 1972. Mosher recounts his experience as...
Show moreVideo interview with Robert (Bob) Mosher, who received an MS in Design from the Institute of Design in 1972. Mosher recounts his experience as a student under Garry Winogrand. Running time is 7:30 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Lutch, Michael, Oral History Interview, 2011
- Creator
- Lutch, Michael, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Michael Lutch, who received an MS in Design from the Institute of Design in 1974. Lutch recounts his experience as a...
Show moreVideo interview with Michael Lutch, who received an MS in Design from the Institute of Design in 1974. Lutch recounts his experience as a student under Arthur Siegel, and how ID informed his vision as a present-day commercial photographer. Running time is 9:13 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Leinwohl, Steffens, Oral History Interview, 2011
- Creator
- Leinwohl, Steffens, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Steffens (Stef) Leinwohl, who received a B.S. in Design from the Institute of Design in 1963. Leinwohl recounts his...
Show moreVideo interview with Steffens (Stef) Leinwohl, who received a B.S. in Design from the Institute of Design in 1963. Leinwohl recounts his experiences as an undergraduate photography student at ID and how the faculty and fellow students influenced him. Leinwohl displays some of his own photographs created while at ID. Running time is 32:12 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Burd, Richard, Oral History Interview, 2011
- Creator
- Burd, Richard, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Richard (Dick) Burd, who received an MS in Design from the Institute of Design in 1970. Burd recounts his experiences as...
Show moreVideo interview with Richard (Dick) Burd, who received an MS in Design from the Institute of Design in 1970. Burd recounts his experiences as a photography student at ID and how his education informs his current photography work. Running time is 10:42 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Langston, Judy Oral History Interview, 2011
- Creator
- Langston, Judy A., Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Judy Langston, who received an MS in Photography from the Institute of Design in 1982. Langston describes the photography...
Show moreVideo interview with Judy Langston, who received an MS in Photography from the Institute of Design in 1982. Langston describes the photography facilities at ID during her time as a student, as well as other experiences. Running time is 8:35 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011
- Title
- Swedlund, Charles, Oral History Interview, 2011
- Creator
- Swedlund, Charles, Walker, Dale, Kuruna, Daniel
- Date
- 2011-05-01
- Description
-
Video interview with Charles Swedlund, who received a B.S. in Photography from the Institute of Design in 1958 and an M.S. in Design shortly...
Show moreVideo interview with Charles Swedlund, who received a B.S. in Photography from the Institute of Design in 1958 and an M.S. in Design shortly thereafter. Swedlund recounts his experiences as a student and faculty member at ID (both on Clark St. and when ID moved to IIT campus in south Chicago) and elsewhere. Running time is 21:30 minutes.
Show less - Collection
- Institute of Design Photography Oral History Project, 2011