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- Title
- IMPROVED SPATIAL-TEMPORAL RECONSTRUCTION FOR CARDIAC AND RESPIRATORY GATED SPECT
- Creator
- Qi, Wenyuan
- Date
- 2014, 2014-12
- Description
-
Myocardial perfusion single photon emission computed tomography (SPECT) is an important imaging technique for evaluating coronary artery...
Show moreMyocardial perfusion single photon emission computed tomography (SPECT) is an important imaging technique for evaluating coronary artery disease. It can provide information of both myocardial perfusion and ventricular function. However, SPECT images su er from both cardiac and respiratory motion blur. In order to reduce the motion degrading, cardiac and respiratory gated SPECT imaging is used. In gated SPECT imaging, due to the lowered counts, the gated images will be more noisy than the ungated ones. Spatiotemporal (4D) processing is often used to reduce the noise level in gated images. In this thesis, we aim to investigate spatial and temporal processing techniques for improving the quality in cardiac and respiratory gated SPECT imaging. First, we will investigate a piecewise spatial smoothing prior based on totalvariation (TV) in 4D cardiac SPECT image reconstruction. In previous studies, it was found that spatial smoothing could adversely a ect the accuracy of 4D reconstruction in cardiac gated SPECT when temporal smoothing was applied, even though it could suppress the noise level. Our goal is to explore whether a piecewise spatial smoothing prior will improve the image accuracy while reducing the noise. Toward this goal, we will compare TV based piecewise spatial smoothing with quadratic spatial smoothing with simulated imaging, in which we will evaluate the lesion detectability. Clinical data will also be used to compare the results as a preliminary test. Motion-compensated temporal smoothing is known to play a key role in 4D cardiac gated SPECT reconstruction. Next, we will investigate whether better motion estimation could further improve the accuracy of reconstructed images. We will consider two di erent motion estimation models and the known motion in simulated experiments. The motion estimation methods are the classic optical ow estimation (OFE) and a periodic motion estimation method. We will evaluate the reconstruction from di erent motion models using several numerical quanti cation metrics. Furthermore, we will demonstrate reconstruction with the two motion estimation models using clinical acquisitions. Respiratory motion is known to cause motion blur in SPECT image reconstruction, and respiratory gated SPECT imaging can be e ective to combat its e ect. We will develop reconstruction techniques in respiratory gated SPECT. We will consider two reconstruction schemes for respiratory gated SPECT. The rst scheme is a post motion compensated reconstruction, in which images at di erent respiratory phases are reconstructed seperately, and afterwards are averaged over all the respiratory gates by motion compensation. The second scheme is a model based motion compensated reconstruction approach, in which one reference gate is used to describe the acquisition data of all the respiratory gates. Due to irregular respiratory motion, the data acquisition in each respiratory gate is not uniformly distributed among the acquisition angles, which would lead to limited-angle artifacts. To correct such artifacts, we propose an angle compensation method in the reconstruction. In order to deal with both cardiac and respiratory motion, we will investigate a 4D reconstruction approach for dual cardiac-respiratory gated SPECT reconstruction. This approach can accommodate the acquired data simultaneously from di erent cardiac and respiratory gates. It can exploit the correlation in the signal component among both the cardiac and respiratory phases. Both simulated experiments and clinical reconstruction will be used for evaluating this reconstruction approach. Due to the radiation risk of myocardial perfusion imaging (MPI) scans, there is an urgent need to lower the radiation dose used in SPECT. However, lower radiation dose will lead to more noisy reconstruction, which is even more serious in gated SPECT. We would explore the potential of using 4D reconstruction for lowering the dose in dual cardiac-respiratory gated SPECT.
Ph.D. in Electrical and Computer Engineering, December 2014
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- Title
- Nibakure Children's Village School
- Creator
- May, Bryan
- Date
- 2010-07-13
- Title
- Sloan Valve Company (sequence unknown), IPRO 306 - Deliverables: IPRO 306 IPRO Day Presentation F09
- Creator
- Delahanty, Sean, Jaouen, Julien, Thakkar, Hetul, Jones, Santiago Guerrero, Kim, Sung, Toor, Hammad, Jalan, Arjun, Soleja, Sikander, Zhang, Yayan
- Date
- 2009-12
- Description
-
Sloan Valve manufactures and distributes commercial valves and plumbing fixtures globally. The IPRO team will work to improve the 'procure to...
Show moreSloan Valve manufactures and distributes commercial valves and plumbing fixtures globally. The IPRO team will work to improve the 'procure to pay' process and also assist in the development of a new warehouse management module.
Sponsorship: Sloan Valve Company
Deliverables for IPRO 306: Sloan Valve for the fall 2009 semester.
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- Title
- USING CONFIDENCE INTERVALS WITH A SMALL SAMPLE SIZE ADJUSTMENT TO ASSESS ADVERSE IMPACT
- Creator
- May, Jill L.
- Date
- 2012-03-27, 2012-05
- Description
-
With increased diversity in the U.S. workforce, there has become a greater need for organizations to defend against accusations of...
Show moreWith increased diversity in the U.S. workforce, there has become a greater need for organizations to defend against accusations of discrimination and thus a need to produce more accurate adverse impact statistics in discrimination cases. The purpose of the present study is to investigate two adjustments to a confidence interval procedure for calculating adverse impact to see if they give more adequate performance over the unadjusted Morris and Lobsenz (2000) confidence interval procedure. A Monte Carlo simulation revealed that using an adjustment for small sample sizes alleviates some of the problems found for the confidence interval procedure found in previous research. Specifically, adding a 0.5 adjustment to the confidence interval procedure increases the accuracy over the unadjusted procedure and the Agresti and Caffo (2000) procedure. Implications for practioners and researchers are included in the discussion.
M.S. in Psychology, May 2012
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- Title
- Smart Binoculars for Military & Civilian Use (sequence unknown), IPRO 350 - Project Plan: IPRO%20350%20Project%20Plan%20F09_redacted
- Creator
- Bubert, Casey, Fairall, Earl, Hopkins, Dong, Hutchins, Sarah, Kobayashi, Jonathan, Mccluskey, John, Pain, Muhammad, Patel, Purvag, Roa, Carlos, Spitler, Noah
- Date
- 2009-12
- Description
-
GPS modules and tracking devices have influenced many advances in modern technology. The data GPS provides has replaced the map and compass,...
Show moreGPS modules and tracking devices have influenced many advances in modern technology. The data GPS provides has replaced the map and compass, and can be crucial in many situations. Its current platform for use however requires the user to utilize a handheld device and direct his/her frame of view to a screen. In many situations there is a need to have eyes on and full awareness of surroundings, something that simply can't be done while holding and viewing a handheld device. To solve this dilemma, team Smart Specs has integrated ideas of GPS, heads-up displays, and datalink technology to form a design that will give the user full hands free capabilities. This device, worn like glasses, allows the user to track objects and even designate objects to be tracked, which are all shown through heads-up display.
Project plan for IPRO 350: Smart Binoculars for Military & Civilian Use for the fall 2009 semester
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- Title
- DIFFERENT EXPLORATION ACTIVITY AND DETECTION THRESHOLD TOWARDS ODOR SETS BETWEEN CONNEXIN 36 KNOCKOUT MICE AND WILD-TYPE MICE
- Creator
- Chai, Xiaomeng
- Date
- 2012-04-16, 2012-05
- Description
-
The sense of smell allows an organism to be aware of the chemical information of the external world. In most land animals, the olfactory...
Show moreThe sense of smell allows an organism to be aware of the chemical information of the external world. In most land animals, the olfactory system enables the perception of both volatile chemicals, as well as pheromones--chemicals released by animals that regulate their social activities. Among several factors that mediate olfaction, connexin 36 (Cx36), a subunit of gap junctions, has been suggested to play a crucial role in the olfactory system. In the research presented herein, I performed habituation/dishabituation studies on both Cx36 knockout (Cx36 KO) and wild-type mice to determine their exploration patterns towards four odorants. The results indicate that Cx36 KO and wild-type mice behaved differently when they were given defined odorants. In general, Cx36 KO mice spent more time exploring odorants. Cx36 KO and wild-type mice also exhibited different detection threshold towards given odorants. Moreover, cross-habituation between benzaldehyde and octaldehyde was established in Cx36 KO mice at the concentration of 10-4%, which was different from that in wild-type mice. These results may suggest important functions of Cx36 gap junctions in odor detection and integration in mammals. Keywords: Connexin 36, gap junction, olfactory system, habituation/dishabituation
M.S. in Biology, May 2012
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- Title
- A study of the "cracking" of petroleum
- Creator
- Heritage, Clark Cable, Hook, Frank William.
- Date
- 2009, 1914
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/studyofcrackingo00heri
Thesis (B.S.)--Armour Institute of Technology, 1914 B.S. in Chemical Engineering, 1914
- Title
- Using Assessment Data to Improve Library Services : presented at ILA 2007 conference: 2007program
- Creator
- Stewart, Christopher, Uth, Charles
- Date
- 2007-10
- Description
-
IIT Libraries conducted LibQUAL+ service quality assessment in 2004 and 2006. This presentation will outline strategies we undertook to...
Show moreIIT Libraries conducted LibQUAL+ service quality assessment in 2004 and 2006. This presentation will outline strategies we undertook to address issues identified in the 2004 assessment, and evaluate their success based on assessment results in 2006. We will also discuss the importance of measuring academic library effectiveness in higher education’s emerging outcomes-based culture.
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- Title
- A Mixed Use High Rise in Mumbai: Board_MixedUse_Irshad_Saleji
- Creator
- Saleji, Irshad
- Date
- 2011-05, 2011-05
- Description
-
C-ward is the neighborhood (in Mumbai) that was designed and developed around 1940 and thereafter there has been no or very little improvement...
Show moreC-ward is the neighborhood (in Mumbai) that was designed and developed around 1940 and thereafter there has been no or very little improvement in infrastructure, which has led to narrow street, unsafe pedestrian and limited open space. C-ward in one of the most prime real-estate location considering it right next to financial district , close to major train station and close to Shoreline. ROMF (Remaking of Mumbai Federation) has taken the initiative to develop the C-ward and the project site part of ROMF development area. City centers have always been source of density because of scarcity of land. The sensible and effective use of such land would be to build vertical (high-rise) and also to have the possibility of expansion for the future development. A mixed use high rise development diversifies the use of space within a single building structure. Combination of living, entertainment, shopping and lodging in single urban structure, helps to utilize the full potential of an urban site.
Sponsorship: Durbrow, John
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- Title
- WIDESPAN: Masters Project
- Creator
- Ninan, Janice
- Date
- 2011-05, 2010-12
- Description
-
Widespan design.Investigating the integration of windmills into longspan structure and investigating the axial forces of tension to span...
Show moreWidespan design.Investigating the integration of windmills into longspan structure and investigating the axial forces of tension to span grater spans using virtual depth concepts with slender lightweight design.
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- Title
- ADVANCED TRACER KINETIC MODELS FOR IMPROVED TUMOR MARGIN DETECTION AND GUIDING THERAPY
- Creator
- Sinha, Lagnojita
- Date
- 2014, 2014-07
- Description
-
Cancer continues to be the second leading cause of death in the world with one in two individuals suffering from some form of cancer within...
Show moreCancer continues to be the second leading cause of death in the world with one in two individuals suffering from some form of cancer within their lifetimes [1]. The main objective in most cancer therapies is to achieve a complete resection of the cancerous cells, which in surgical approaches is evident from the diagnosis of positive resection margins during postoperative pathology. However, pathological analysis is performed after the patient has been discharged. Thus technologies capable of identifying tumor margins in resected samples intraoperatively could substantially reduce the psychological and economical burden of “call-back” surgeries. As a step in this direction, a wide-field Raman spectroscopy system was employed, which has the capacity to discriminate between tumor and healthy tissue through a “dual-tracer” staining approach within the surgical window. The approach entails dipping the resected tissue in two tracers: one targeted to a cancer specific cell-surface receptor, and another left “untargeted”. In this experiment human glioma (U251) and human epidermoid (A431) tumors were grown subcutaneously in ten nude athymic mice. The data obtained from the Raman spectra of different tissue specimens were then analyzed through tracer kinetic modeling to quantify cancer molecule abundance as a surrogate of cancer presence. The salient finding in this study was that the model was able to predict the expected differences in EGFR concentration amongst the healthy tissue, U251, and A431. Kinetic model estimation of the ratio of EGFR concentration in U251 and A431 cell lines were in the ratio of 2:1, which correlates, with the expected ratio of EGFR concentration determined by flow cytometry which was close to 4:1. This technology not only promises to xii highlight tumor margins on a molecular level but can also be leveraged to analyze the molecular environment of the tumor to guide adjuvant precision therapies. Tracer kinetic modeling approaches were also applied to a guided precision therapy called Photodynamic therapy. Not only could the analysis of data provide parameter values for the tracer kinetics but an approach was also developed which with only a few initial data points could predict the time optimal for therapy in advance of the drug concentration maximum.
M.S. in Electrical Engineering, July 2014
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- Title
- IN-PACKAGE DECONTAMINATION OF SALMONELLA MONTEVIDEO ON BLACK PEPPER USING PULSED LIGHT TECHNOLOGY
- Creator
- Xu, Xinran
- Date
- 2016, 2016-07
- Description
-
This study evaluated the efficacy of three pulsed light systems (1.8, 3 and 100 Hz) for inactivation of Salmonella Montevideo on the surface...
Show moreThis study evaluated the efficacy of three pulsed light systems (1.8, 3 and 100 Hz) for inactivation of Salmonella Montevideo on the surface of black pepper. The impact of frequency, treatment time and distance from the lamp on the rate of inactivation was studied. A reduction of 4.21 1og10 CFU/g was achieved with a 35 s treatment at 16.6-cm from lamp at 1.8 Hz. Similarly, reductions of 4.72 CFU/g and 4.70 CFU/g were obtained at 14.1-cm after 35 s treatment at 3 Hz and 100 Hz, respectively. Temperature measurement of packed and unpacked black pepper indicated that packaging material absorbed a small amount of energy. Measurement of surface and internal temperature suggested that temperature below the surface increased far less than surface temperature. For instance, temperature on the surface of the black pepper can go up to 200 °C as measured by the infrared camera within 30 to 40 s treatment. However, the temperature at 1 mm below the surface was up to 100 °C depending upon the distance from the lamp. The color of the black pepper did not change after pulsed light treatment (p>0.05). These results suggest that pulsed light can potentially be used to inactivate pathogens on black pepper surface without adversely affecting its quality.
M.S. in Food Safety and Technology, July 2016
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- Title
- Sloan Valve Company (sequence unknown), IPRO 306 - Deliverables: IPRO 306 Abstract F09
- Creator
- Delahanty, Sean, Jaouen, Julien, Thakkar, Hetul, Jones, Santiago Guerrero, Kim, Sung, Toor, Hammad, Jalan, Arjun, Soleja, Sikander, Zhang, Yayan
- Date
- 2009-12
- Description
-
Sloan Valve manufactures and distributes commercial valves and plumbing fixtures globally. The IPRO team will work to improve the 'procure to...
Show moreSloan Valve manufactures and distributes commercial valves and plumbing fixtures globally. The IPRO team will work to improve the 'procure to pay' process and also assist in the development of a new warehouse management module.
Sponsorship: Sloan Valve Company
Deliverables for IPRO 306: Sloan Valve for the fall 2009 semester.
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- Title
- TASK/STAFFING-TECHNOLOGY FIT IN CONSTRUCTION SCHEDULING
- Creator
- Yang, Juneseok
- Date
- 2015, 2015-07
- Description
-
Construction managers use scheduling methods such as the critical path method (CPM) and linear scheduling methods (LSM) to improve the outcome...
Show moreConstruction managers use scheduling methods such as the critical path method (CPM) and linear scheduling methods (LSM) to improve the outcome of their project. CPM is a popular scheduling method that is mostly based on precedence relationships and the identification of the longest path through a network. LSMs are based on a continuous flow of resources and are used mostly on projects that exhibit repetitive characteristics. Despite the many obvious advantages of CPM, its use in construction has been limited. LSMs are much less frequently used than CPM, although the general consensus is that LSMs are quite effective in projects composed of activities of repetitive nature. Understanding the reasons why these methods are not used as extensively as expected could improve their level of acceptance in the construction industry. The link between construction scheduling methods and the tasks expected to be performed by schedulers has been an on-going concern in the construction industry. The link between construction scheduling methods and the capabilities of the scheduling staff has also been an important issue. This study proposes a combined task/staffing-technology fit model to understand why CPM and LSM are not used as extensively as expected in construction scheduling: (1) a task-technology fit model that aims to measure the extent to which a construction scheduling method functionally matches the tasks expected to be performed by the scheduling staff; (2) a staffing-technology fit model that aims to measure the extent to which a construction scheduling method matches the staff`s experience, know-how and capabilities. The models that are proposed are an answer to the lack of proper instruments for evaluating the extent to which scheduling methods are used in the industry. A questionnaire survey was administered to professionals listed in the directory of the Construction Management Association of America (CMAA) who have many years of experience in construction scheduling. Statistical analyses were performed to determine statistical significance of the differences between the level of agreement concerning task-technology fit and staffing-technology fit for CPM and LSM applications. Findings indicate that there are significant differences between the opinions of CPM users and LSM users. This means that task-technology fit is much different in CPM and LSM applications. Similarly, staffing-technology fit is also quite different in CPM and LSM applications.
M.S. in Civil Engineering, July 2015
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- Title
- Oil Rig Eco Hotel
- Creator
- Marcan, Stephanie
- Date
- 2011, 2011-05
- Description
-
By refashioning the design and programmatic use of an offshore oil rig into a luxury hotel for ecotourists, a new age of responsible travel...
Show moreBy refashioning the design and programmatic use of an offshore oil rig into a luxury hotel for ecotourists, a new age of responsible travel may emerge. By twisting the symbol of oil dependency into an ecologically preserved, environmentally accountable and revenue-producing prototype, the ideals of reuse, energy and environment can be viewed through a new lens. This design creates interesting and innovative living spaces and environments aided by sustainable integrations to create a “living machine” that establishes connections between all building systems as well as inhabitant inputs and outputs resulting in an energy independent habitat.
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- Title
- COMPUTATIONAL ACCESS FLOW REDUCTION EFFECT ON WALL SHEAR STRESS IN BRACHIOCEPHALIC FISTULAE
- Creator
- Wlodarczyk, Marta P.
- Date
- 2017, 2017-05
- Description
-
The population of patients with end stage renal disease (ESRD) is growing at a rate higher than the global population. The only viable...
Show moreThe population of patients with end stage renal disease (ESRD) is growing at a rate higher than the global population. The only viable treatment for these patients is a kidney transplant. However, in the absence of a suitable kidney donor, renal patients are left with hemodialysis as a renal replacement therapy. Hemodialysis is facilitated through arteriovenous fistula (AVF), and the particular interest in this investigation is brachiocephalic fistula (BCF). The survival of dialysis patients depends on maintaining patency of fistula over a prolonged period of time. The extreme hemodynamic environment that is created by BCF triggers the onset of neointimal hyperplasia (NH) in most renal dialysis patients, which leads to access failure via stenosis. This is because the hemodynamics in AVF are well outside the normal physiological range. Computational fluid dynamics (CFD) along with shape optimization allows for the study of the hemodynamic parameters such as wall shear stress that have been shown to be detrimental in the future occurrence of cephalic arch stenosis. In this study, CFD modeling and identification of hemodynamic patterns was possible in three dimensions due to advanced post processing of IVUS patient-specific geometries. A method utilizing 3D CFD and shape optimization has been developed to implement Miller’s banding method used in clinical practice to evaluate its impact on WSS and onset of neointimal hyperplasia. The level of banding represented by a constriction is in fact a patient specific value and is not a trivial solution of minimum flow rate necessary to conduct hemodialysis; hence suggesting that even restoring the inlet velocity to the velocity pre-fistula creation might not reduce incidence of cephalic arch stenosis. The findings of this study support the previous hypothesis that non-homeostatic WSS distributions trigger neointimal hyperplasia and resulting venous stenosis. The important outcome is that the presented computational framework allows for evaluation of Miller's banding method for reducing the blood flow rate via surgical constriction and identification of a patient-specific banding level that restores the WSS to the normal physiological range.
M.S. in Mechanical and Aerospace Engineering, May 2017
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- Title
- Overlap Overlay: Overlap Overlay Board
- Creator
- Wankel, Jordan
- Date
- 5/4/2011, 2011-05
- Description
-
The purpose of this overlay is to provide the proper mechanics which allows a new type of home ownership while addressing current urban...
Show moreThe purpose of this overlay is to provide the proper mechanics which allows a new type of home ownership while addressing current urban vacancy. The overlay attempts to be democratic. It establishes basic rules based on the existing block requirements, while also providing flexibility within. Residents voluntarily participate in the system, benefiting from the whole. Social interactions, block orientated activities, and housing arrangements expand and contract over time.
Sponsorship: Goodman, David
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- Title
- DISPARITY ESTIMATION WITH SEGMENT-BASED MULTI-STEP DISPARITY REFINEMENT
- Creator
- Anand, Bhaskar
- Date
- 2012-07-20, 2012-07
- Description
-
Stereo Vision is one of the fundamental problems of computer vision and one of the oldest and heavily investigated areas of 3D Vision. Recent...
Show moreStereo Vision is one of the fundamental problems of computer vision and one of the oldest and heavily investigated areas of 3D Vision. Recent advances in stereo matching methodologies have allowed researchers to develop several stereo vision techniques. But it has been observed that most of these methodologies mainly focus on only one aspect, either the execution time or the quality of the generated depth map. While attempts to maximize the quality of the depth map have been successfully achieved, it is however observed that the execution time has increased signi cantly, thereby rendering them un t for real time implementation. In this thesis, an attempt to solve the above said problem is presented, in which we combine the e ects of two important stereo matching concepts, one attempting to increase the depth map quality, while the other being that of having an algorithmic structure so that in future, it can be used for real-time implementation. By applying hardware-friendly methods to the framework of segment based stereo matching, the method is said to achieve a good quality depth map. This work also discusses the various challenges which it takes care of plus the study of performance compared to existing methods.
M.S. in Electronical Engineering, July 2012
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- Title
- Finding Uses for Alternative Fuels in Intermodal Transportation Hubs (sequence unknown), IPRO 307 - Deliverables: IPRO 307 IPRO Day Presentation F09
- Creator
- Balakirev, Konstantin, Beau‐luby, Ryan, Bouikidis, John, Cargill, Matthew, Dziuba, David, Kehoe, Matthew, Slonski, Bryan, Tesfaye, Melat, Wiese, Matthew, Wiseman, Christopher, Zook, Joel
- Date
- 2009-12
- Description
-
Chicago, being the third largest freight hub in the world, needs an efficient movement of goods for the increasing freight shipments.
Sponsorsh...
Show moreChicago, being the third largest freight hub in the world, needs an efficient movement of goods for the increasing freight shipments.
Sponsorship: Mi-Jack
Deliverables for IPRO 307: Finding Uses for Alternative Fuels in Intermodal Transportation Hubs for the fall 2009 semester.
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- Title
- DESIGN OF A SECURE WIRELESS HEALTH DATA MANAGEMENT SYSTEM FOR PERSONAL BODY SENSOR NETWORKS
- Creator
- Wu, Pingping
- Date
- 2016, 2016-07
- Description
-
In this research, we have explored and verified the data security and real-time performance of a Secure Wireless Health Data Management (SWHDM...
Show moreIn this research, we have explored and verified the data security and real-time performance of a Secure Wireless Health Data Management (SWHDM) system applied to personal body sensor networks. Security must be considered critical for any healthrelated information system. The SWHDM examined for this study consists of multiple wireless health-related sensors, one central data coordinator called the Wireless Intelligent Personal Communication Node (W-iPCN), a custom application designed for an Android smartphone, and a remotely located central medical server. There are two major communication channels involved in wireless data transmission. We extensively studied the body sensor data for wireless data transmission. We also focused on applying cryptographic algorithms in order to provide data confidentiality, integrity and authentication. This security assessment aims to observe the performance of data encryption and decryption, and feasibility to remotely monitor patients' health in realtime. The test result based on ECG examples is favorable towards the real-time processing requirements of the system.
M.S. in Electrical Engineering, July 2016
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