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- Title
- Two Essays on Cryptocurrency Markets
- Creator
- Fan, Lei
- Date
- 2022
- Description
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Understanding the dependence relationships among cryptocurrencies and equity markets is of interest to both academics and researchers. This...
Show moreUnderstanding the dependence relationships among cryptocurrencies and equity markets is of interest to both academics and researchers. This dissertation is comprised of two essays to add to this understanding. In the first essay, I investigate the interdependencies among the level of informational efficiency of four cryptocurrencies. I examine the correlations between the market efficiencies of cryptocurrencies using the rolling window method. I find that the correlations between those levels of market efficiencies are time-varying and influenced by the market condition and external events. I extend the study by employing Granger causality tests to analyze the causal relationships among these levels of market efficiency. I find that the Granger causalities among the levels of the cryptocurrency market efficiencies are time-varying and impacted by the level of the market efficiencies. In the second essay, I investigate the pairwise dependencies and causalities between the returns of the cryptocurrencies and six equity market indices. I examine the pairwise dependencies between the returns of cryptocurrencies and those of the equity indices by using the DCC-GARCH framework. I find the dynamic conditional correlations between the cryptocurrencies and equity indices are time-varying and generally weak. Furthermore, I study the causal relationship between cryptocurrencies and equity indices by employing the rolling Granger causality test. I find that the Granger causalities between cryptocurrencies and equity indices are time-varying, and more unidirectional Granger causalities are found from cryptocurrencies to equity indices. In addition, I examine the impact of cryptocurrency returns on the correlations between the equity market indices, and likewise, the impact of equity market returns on the correlations between the cryptocurrencies. I find that the cryptocurrency price fluctuations have minimal impact on the correlations between equity indices. Moreover, the dynamic conditional correlation between cryptocurrencies is unaffected by equity price innovations except for some extreme events. These findings could have implications for understanding the relationships among cryptocurrencies and equity markets and for investors wishing to incorporate these relationships in their portfolio choices.
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- Title
- PLAYER MOTIVATION AND TRAINING EFFECTIVENESS: INSIGHTS FROM A STRUCTURAL MODEL OF GAME-BASED LEARNING
- Creator
- Gandara, Daniel A.
- Date
- 2022
- Description
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Digital game-based learning (DGBL) delivers training through video games. Practitioners are using DGBL in attempts to increase motivation,...
Show moreDigital game-based learning (DGBL) delivers training through video games. Practitioners are using DGBL in attempts to increase motivation, promote learning, and increase transfer in training. Theory and models of DGBL aim to explain how motivation is created to yield these benefits, and studies have compared DGBL to traditional methods, yet the tenets of these theories remain largely unexamined. The present study tested the process-outcome link of Garris et al.’s (2002) input-process-outcome model, examined the effect of positive and negative user judgments on behavior and learning, and expanded the model to include trainee reactions and adaptive transfer. Participants (N = 254) learned about identifying misinformation online by playing Fake It to Make It, a social-impact game that teaches core critical thinking skills. Autoregressive cross-lagged (ARCL) panel analysis was used to analyze and compare models to test the hypothesized relationships among judgments and behavior scores across six game levels in predicting six learning outcomes, including adaptive transfer tasks evaluating online sources. Findings indicated that each judgment was predicted by its own lagged judgment and lagged behavior. Additionally, positive user judgments predicted reactions, post-training self-efficacy, and motivation to transfer, while frustration inhibited declarative knowledge. Results also demonstrated that behavior and declarative knowledge predicted performance on the adaptive transfer tasks. Research recommendations and practice implications are discussed relative to using games to deliver training with emphasis on motivational properties and targeted outcomes.
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- Title
- COMPUTATIONAL FLUID DYNAMICS SIMULATION OF CARBON CAPTURE UNIT USING AN AMINE-BASED SOLID SORBENT
- Creator
- Esmaeili Rad, Farnaz
- Date
- 2021
- Description
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Carbon capture and sequestration (CCS) is one of the key technologies to reduce the emission of carbon dioxide, including that from exiting...
Show moreCarbon capture and sequestration (CCS) is one of the key technologies to reduce the emission of carbon dioxide, including that from exiting flue gas of fossil fuel-fired power plants. The goal of this project is the development of a computational fluid dynamics (CFD) model to predict the extent of CO2 capture in a circulating fluidized bed carbon capture unit using novel amine-based solid sorbents.In this study, first the hydrodynamics of the carbonation section of the carbon capture unit was investigated. Then, the performance of the amine-based solid sorbents toward capturing carbon dioxide from flue gas and the extent of CO2 adsorption in the carbonation section were studied. At the second stage of the study, the regeneration of the sorbents and desorption of carbon dioxide from carbonated solid sorbents in the regeneration section of the carbon capture unit was investigated. At the third stage of the study, the hydrodynamics of the entire loop of the integrated carbonation and regeneration sections were simulated. Two-dimensional non-reactive CFD simulations of the entire loop, including the carbonator, regenerator, and two loop-seal fluidized beds, were performed to study the details of the solid circulation in the system in a stable operational condition. At the fourth stage of the study, the effect of the carbonated solids’ residence time in the regeneration section was investigated by extending the regenerator fluidized bed height and adding to the volume of the system. Heated surfaces, which resembled heating coils in the regenerator cylinder, were also added to the system to investigate the effect of the temperature. The heated surface of the immersed coils in the bed provided sufficient energy for the endothermic regeneration reaction to keep the temperature of the bed at the desired temperature. Finally, the verified models of the carbonation section, the regenerations section, and non-reactive simulation of the CFB loop were used to simulate the entire circulating fluidized bed carbon capture unit, with an integrated carbonator and regenerator system using amine-based solid sorbents. The extent of CO2 capture in the carbonation section and desorption of carbon dioxide in the regeneration section were predicted. Our study showed the potential of continuous carbon capture by amine-based solid sorbents through the circulating fluidized bed CO2 capture unit.
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- Title
- Algorithms for Discrete Data in Statistics and Operations Research
- Creator
- Schwartz, William K.
- Date
- 2021
- Description
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This thesis develops mathematical background for the design of algorithms for discrete-data problems, two in statistics and one in operations...
Show moreThis thesis develops mathematical background for the design of algorithms for discrete-data problems, two in statistics and one in operations research. Chapter 1 gives some background on what chapters 2 to 4 have in common. It also defines some basic terminology that the other chapters use.Chapter 2 offers a general approach to modeling longitudinal network data, including exponential random graph models (ERGMs), that vary according to certain discrete-time Markov chains (The abstract of chapter 2 borrows heavily from the abstract of Schwartz et al., 2021). It connects conditional and Markovian exponential families, permutation- uniform Markov chains, various (temporal) ERGMs, and statistical considerations such as dyadic independence and exchangeability. Markovian exponential families are explored in depth to prove that they and only they have exponential family finite sample distributions with the same parameter as that of the transition probabilities. Many new statistical and algebraic properties of permutation-uniform Markov chains are derived. We introduce exponential random ?-multigraph models, motivated by our result on replacing ? observations of a permutation-uniform Markov chain of graphs with a single observation of a corresponding multigraph. Our approach simplifies analysis of some network and autoregressive models from the literature. Removing models’ temporal dependence but not interpretability permitted us to offer closed-form expressions for maximum likelihood estimators that previously did not have closed-form expression available. Chapter 3 designs novel, exact, conditional tests of statistical goodness-of-fit for mixed membership stochastic block models (MMSBMs) of networks, both directed and undirected. The tests employ a ?²-like statistic from which we define p-values for the general null hypothesis that the observed network’s distribution is in the MMSBM as well as for the simple null hypothesis that the distribution is in the MMSBM with specified parameters. For both tests the alternative hypothesis is that the distribution is unconstrained, and they both assume we have observed the block assignments. As exact tests that avoid asymptotic arguments, they are suitable for both small and large networks. Further we provide and analyze a Monte Carlo algorithm to compute the p-value for the simple null hypothesis. In addition to our rigorous results, simulations demonstrate the validity of the test and the convergence of the algorithm. As a conditional test, it requires the algorithm sample the fiber of a sufficient statistic. In contrast to the Markov chain Monte Carlo samplers common in the literature, our algorithm is an exact simulation, so it is faster, more accurate, and easier to implement. Computing the p-value for the general null hypothesis remains an open problem because it depends on an intractable optimization problem. We discuss the two schools of thought evident in the literature on how to deal with such problems, and we recommend a future research program to bridge the gap those two schools. Chapter 4 investigates an auctioneer’s revenue maximization problem in combinatorial auctions. In combinatorial auctions bidders express demand for discrete packages of multiple units of multiple, indivisible goods. The auctioneer’s NP-complete winner determination problem (WDP) is to fit these packages together within the available supply to maximize the bids’ sum. To shorten the path practitioners traverse from from legalese auction rules to computer code, we offer a new wdp formalism to reflect how government auctioneers sell billions of dollars of radio-spectrum licenses in combinatorial auctions today. It models common tie-breaking rules by maximizing a sum of bid vectors lexicographically. After a novel pre-solving technique based on package bids’ marginal values, we develop an algorithm for the WDP. In developing the algorithm’s branch-and-bound part adapted to lexicographic maximization, we discover a partial explanation of why classical WDP has been successful in using the linear programming relaxation: it equals the Lagrangian dual. We adapt the relaxation to lexicographic maximization. The algorithm’s dynamic-programming part retrieves already computed partial solutions from a novel data structure suited specifically to our WDP formalism. Finally we show that the data structure can “warm start” a popular algorithm for solving for opportunity-cost prices.
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- Title
- THE IMPACT OF SHARED RECRUITMENT INFORMATION ON APPLICANT OUTCOMES AND THE INFLUENCE OF MODERATING VARIABLES
- Creator
- Savage, Catherine M.
- Date
- 2022
- Description
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Organizations are currently experiencing one of the most challenging environments when it comes to recruiting talent. What started in the...
Show moreOrganizations are currently experiencing one of the most challenging environments when it comes to recruiting talent. What started in the 1990s as the “War for Talent,” in which organizations faced fierce competition when hiring and retaining employees, has persisted, and grown more competitive, post-pandemic. As a result, organizations must re-evaluate their recruitment strategies and find ways to connect with job candidates that will increase the probability that they will pursue open job positions. Thus, we examined how sharing different information regarding pay, diversity statements, and mentoring benefits with 250 potential job applicants, based in the US, may influence their attraction to an organization, perceived person-organization fit, and their intention to pursue the job that was posted. We also examined how ethnicity, gender, and age can influence the job candidates’ perception of the information provided. Results from this research partially supported our hypothesized outcomes. Presenting more information to participants (rather than less) generally had a positive impact on organization attraction and intentions to pursue the position posted in the job advertisement. However, the amount of information shared to participants did not influence perceptions of person-organization fit. Additionally, while ethnicity did not moderate the relationship between amount of information shared and the outcome variables, gender and age were found to influence participants’ reaction to the information provided and their subsequent level of organizational attraction and intention to pursue. Implications and avenues for future research are discussed.
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- Title
- Control and Operation of Microgrids and Networked Microgrids
- Creator
- Sheikholeslami, Mehrdad
- Date
- 2022
- Description
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This dissertation presents the practical operation and control of microgrids and networked microgrids, particularly, the networked IIT Campus...
Show moreThis dissertation presents the practical operation and control of microgrids and networked microgrids, particularly, the networked IIT Campus Microgrid (ICM) and Bronzeville Community Microgrid (BCM). Microgrids (MGs) provide a potential solution to accommodating renewable and distributed energy resources (DERs). MGs and the networked form of MGs, i.e., networked microgrids or NMGs, have received significant attention in the past two decades. However, several details are often neglected in the literature that need to be considered for the practical operations of MGs and NMGs. First, there is a need for a step-by-step sequence of operations (SOO) that clearly defines the procedures for changing the operation modes of MGs and NMGs for their reliable and resilient operation. Second, there is a need to develop new control strategies for the centralized and distributed control of MGs and NMGs that are resilient to extreme events and are also more sustainable than the ones available in the literature. Third, there is a need for developing the model of MGs and NMGs in a real-time simulator to safely evaluate the performance of the control and operation of MGs and NMGs. Finally, to close the engineering loop, there is a need to connect the digital and physical layers which are known as digital twins. This dissertation proposes solutions for these four requirements and presents results to evaluate the performance of the proposed solutions. First, an SOO is proposed to enable the reliable and safe transition between different microgrid operation modes. The proposed SOO is adaptable to any MG and NMG with minor modifications. Second, for the centralized control, a DER control model is proposed that allows for the regulated power exchange between networked MGs to ensure information privacy and respect the electrical boundary of each MG. For the distributed control, two control schemes are proposed that are resilient to extreme cases, allow the integration of renewable energy resources (RES), and require the minimum intervention of the operators. Third, several techniques are proposed that can be adopted for developing the real-time models of MGs and NMGs. Finally, as a proof of concept, a digital twin of a microgrid with connections between the physical and digital layers is implemented and tested. The IIT Campus Microgrid (ICM) and Bronzeville Community Microgrid (BCM), as well as their networked form (networked ICM-BCM), are selected as the practical testbeds and are modeled in Real-time Digital Simulator (RTDS). The RTDS model is interfaced with microgrid master controllers (MMC) for real-time data exchange and the performance of the MMCs and the distributed control strategies are tested to illustrate the importance of adopted methods in the real-time control of MGs and NMGs. Finally, a proof of concept for the digital twin of ICM is presented.
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- Title
- WHAT IMPACT DO NUMBER TALKS HAVE ON ELEMENTARY CLASSROOM MATHEMATICAL DISCOURSE AND STUDENT AND TEACHER ATTITUDES TOWARD MATHEMATICS?
- Creator
- Sleezer, Meghan V
- Date
- 2021
- Description
-
Number Talks, created in the early 1990s by Ruth Parker and Kathy Richardson, have gained popularity in the mathematics education community...
Show moreNumber Talks, created in the early 1990s by Ruth Parker and Kathy Richardson, have gained popularity in the mathematics education community over the past decade with the publication of the book series Number Talks (Parrish, 2010, 2014), and especially since the publication of Making Number Talks Matter (Humphreys & Parker, 2015). All in all, the authors contend Number Talks can bring joy into the classroom (Humphreys and Parker, 2015, p. 6), improving student attitudes about mathematics and ultimately allowing for a more productive disposition. The characteristic that separates Number Talks from other pedagogical tools is the disconnectedness from the rest of the lesson: Number Talks need not build up to or build upon the day’s objective. Thus, what the authors argue is that the activity of Number Talks itself – albeit disconnected from the day’s objective – improves all of the aforementioned skills, regardless of what occurs during the remainder of each class session.Eight teachers from five different Chicago-area private grade schools implemented Number Talks in their 3rd-5th grade classrooms for four to six weeks in the early part of the year 2020. Student attitudes toward mathematics and toward mathematical discourse were assessed by way of survey and classroom observation before and after implementation. Classroom interactions and levels of mathematical discourse during the normal class time (outside of the Number Talk session) were assessed before and during implementation. No significant changes (positive or negative) relating to any measure were found. Teachers noticed that students who enjoyed math before the implementation also enjoyed Number Talks, while students who struggled with math were mostly disenchanted with Number Talks. Future research includes exploring whether tailoring Number Talks to relate to the upcoming lesson improves the positive effects advertised by the authors. Teacher professional development related to ambitious teaching practices (NCTM, 2017) and growth mindset (Boaler, 2016b) may complement the use of Number Talks to result in improved attitudes and discourse.
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- Title
- Do Numeric Performance Ratings Have Any Merit?
- Creator
- Sanders, Emily Kathleen
- Date
- 2022
- Description
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Numeric performance ratings have been a component of performance evaluation for decades (Prowse & Prowse, 2009; Pulakos, Mueller-Hanson & Arad...
Show moreNumeric performance ratings have been a component of performance evaluation for decades (Prowse & Prowse, 2009; Pulakos, Mueller-Hanson & Arad, 2019). Yet, in recent years their necessity has been questioned (Adler, Campion, Colquitt, Grubb, Murphy, Ollander-Krane, & Pulakos, 2016), with some organizations going so far as to remove numeric ratings entirely (Capelli & Tavis, 2016; Rock, Davis & Jones, 2014; Burkus, 2016). Unfortunately, this practice has been largely unexamined in an empirical manner. The present study tested whether the claim – that numeric ratings do not matter – holds up in all cases. This is done by exploring whether the presence or absence of numeric ratings, impacts employee perceptions of fairness associated with the appraisal. As numeric ratings are argued to be a mechanism for communicating a fair, standard, and consistent practice, the study aimed to understand if the mere presence of numeric ratings may offset some of the negative reaction employees have toward performance appraisal when they have poor-quality relationships with their supervisors. Findings indicated that while employee-manager relationship quality (assessed via Leader-Member Exchange) has a direct relationship with perceptions of fairness associated with the appraisal, the presence of numeric ratings did not moderate this relationship. Practical implications and future research recommendations are discussed.
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- Title
- Stimulation-Responsive Materials for the Treatment of Disordered Tissues
- Creator
- Clutter II, Elwin Dean
- Date
- 2022
- Description
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Microenvironments offer physical and chemical cues to cells that affect their behavior. These cues can be bioactive chemicals such as drugs...
Show moreMicroenvironments offer physical and chemical cues to cells that affect their behavior. These cues can be bioactive chemicals such as drugs and cytokines, matrix cues like stiffness and composition, and electrical signals as seen in membrane potentials and epithelial wound healing. Controlling these cues can drive cell behavior toward apoptosis, proliferation, or changes in protein expression. In this thesis research, three components were used to model changes in cell behavior: the near infrared dye indocyanine green (ICG), silk fibroin (SF) from Bombyx mori silkworm cocoons, and carbon nanotubes (CNT). The mechanism of ICG photobleaching was studied for the efficacy to kill neuroblastoma cancer cells. ICG was twice as effective at killing neuroblastoma than fibroblast cells. Albumin stabilized monomeric ICG to enhance photobleaching by improving light interaction, and photodegradation of ICG into α,β-unsaturated aldehydes led to significant reduction of proliferation in neuroblastoma cells by targeting cell signaling components such as protein transcription factors. SF-ICG composite materials were developed into films and electrospun fibers. These composite materials were examined as light-activated wound coverings to control bleeding in hemorrhage, using ICG’s photothermal effect. ICG added an absorbance peak to SF at 805 nm. Irradiation decreased this peak, produced a new absorbance peak at 352 nm, and an increased fluorescence peak around 490 nm, showing photochemical changes that may be useful in sensor design. Increased heat production from irradiation of SF-ICG occurred in the films with 0.2% w/w ICG in SF during 1 min irradiation, whereas SF-ICG fibers required improvement of processing by ethanol vapor treatment (EVT) to reduce loss of ICG during preparation. EVT improved ICG retention in SF fibers during sterilization with 70% ethanol solution thus improving heat generation in the SF-ICG fibers. Heat evolved from SF-ICG 0.2% film solidified bovine blood within 42 s, with visible changes after the first 6 s. SF electrospun fibers were investigated to optimize silk preparation to reduce diameters and increase alignment to mimic local native cell environments with and without CNT to add conductivity for enhancement of electrical stimulation. CNT reduced SF fiber diameters below 1% and effected alignment differently as the concentration increased. Longer degumming times decreased SF fiber diameters and alignment of the same concentration. The optimized conditions were 1 h degumming time with 1.5 ml/h flow rate at a concentration of 100 mg/ml spinning solution with 0.25% CNT to form fibers with 1.36 (± 0.09) µm diameter and 0.31 (± 0.01) a.u. alignment. Additionally, SF fibers were used as a long-term cell growth scaffold to compare with decellularized native tissue. Decellularized tissue decreased fibroblast mRNA expression of collagen type 1, lysyl oxidase-like 1 and matrix metalloproteinase 9, while all other genes expression was the same as cells on plastic. The SF fiber scaffold reduced fibroblast expression of collagen type 3 compared to growth on plastic, and both collagen types 1 and 3 increased over growth time on SF. Immunofluorescence staining showed both collagens newly deposited on the SF scaffold and improved over time. In conclusion, proteins stabilized ICG monomers to improve light interaction, efficacy of photobleaching, and heat evolution to induce apoptosis in neuroblastoma and agglutination of blood in SF composites. Irradiation of ICG enhanced changes in optical properties and may have sensor applications. The decrease of genes may be due to each scaffold having lower stiffness compared to plastic. ICG and SF are both materials with applications as biological scaffolds in pelvic organ prolapse and treatment of neuroblastoma and hemorrhage.
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- Title
- SOLID-STATE SMART PLUG DEVICE
- Creator
- Deng, Zhixi
- Date
- 2022
- Description
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Electrical faults are a leading cause of residential fire, and flexible power cords are particularly susceptible to metal or insulation...
Show moreElectrical faults are a leading cause of residential fire, and flexible power cords are particularly susceptible to metal or insulation degradation that may lead to a variety of electrical faults. Smart Plugs are a type of plug-in device controlling electrical loads via wireless communication for consumer market. However, there is lack of circuit protection features in existing Smart Plug products. Moreover, there is no previous product or research on Smart Plug with circuit protection features. This thesis introduces a new Smart Plug 2.0 concept which offers all-in-one protection against over-current, arc, and ground faults in addition to the smart features in Smart Plug products. It aims at preventing fire and shock hazards caused by degraded or damaged power cords and electrical connections in homes and offices. It offers microsecond-scale time resolution to detect and respond to a fault condition, and significantly reduces the electrothermal stress on household electrical wires and loads. A new arc fault detection method is developed using machine learning models based on load current di/dt events. The Smart Plug 2.0 concept has been validated experimentally. A 120V/10A solid-state Smart Plug 2.0 prototype using power MOSEFTs is designed and tested. It has experimentally demonstrated the comprehensive protection features against all types of electrical faults.
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- Title
- Fatigue Life Prediction for Structures with Interval Uncertainty
- Creator
- Desch, Michael R.
- Date
- 2022
- Description
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A new method for reliable fatigue life prediction in metal structural components is developed where uncertainties are quantified using...
Show moreA new method for reliable fatigue life prediction in metal structural components is developed where uncertainties are quantified using interval variables. Using this crack-initiation-based method, first, the uncertainties in laboratory test data for the fatigue failure of a structural detail are enumerated. This uncertainty quantification is performed through an interval-based enveloping procedure that relates the interval stress ranges to the number of cycles to failure, leading to the construction of an interval S-N relationship. Next, the uncertainties in field test data are enumerated in the extremum values of each stress range, as intervals, leading to the construction of interval stress ranges. For both the laboratory and field data uncertainty analyses, the mean stress effects are considered. Next, the interval damage accumulated over the duration of the field data is determined using the constructed interval S-N relationship and the obtained interval stress ranges. Then, the interval existing damage and interval remaining life are determined. Finally, as a conservative measure, the minimum remaining fatigue life is obtained in which all uncertainties are considered. Three numerical examples illustrating the developed method are presented, and the results are compared with results obtained by both Monte Carlo simulation and optimization. Using this method, for the numerical examples considered, it is shown that the results for bounds on the existing damage and the remaining fatigue life are sharp. Moreover, due to its set-based approach, the method is significantly more computationally efficient when compared with iterative procedures.
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- Title
- Stress-Induced Habitual Responding as a Maintenance Factor in Bulimia Nervosa Spectrum Disorders
- Creator
- Dougherty, Elizabeth Nash
- Date
- 2022
- Description
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Individuals with bulimia nervosa spectrum disorders often compulsively engage in binge eating and purging, despite life threatening...
Show moreIndividuals with bulimia nervosa spectrum disorders often compulsively engage in binge eating and purging, despite life threatening consequences. Little is known about factors that contribute to compulsivity in these conditions. The purpose of this study was to investigate whether stress and habitual control over bulimic behaviors play a role in maintaining symptoms in these disorders, using ecological momentary assessment. Women with bulimia nervosa spectrum disorders (N = 81) completed self-report baseline questionnaires and a 14-day EMA protocol which involved daily assessments of stress, negative affect, bulimic behaviors, and contextual antecedents to bulimic behaviors. The results indicated that baseline habitual control over binge eating and purging were not associated with global eating pathology or eating disorder-related clinical impairment. However, exploratory analyses revealed that habitual control over binge eating and purging were associated with more frequent engagement in these behaviors during the previous four weeks. Neither stress appraisal nor stressor frequency were associated with habitual control over bulimic behavior during the EMA period. In terms of affect trajectories surrounding bulimic behaviors, negative affect increased in the hours leading up to these behaviors, decreased in the hours following these behaviors, and was higher immediately after these behaviors compared to before. Habitual control over binge eating and purging did not moderate temporal relations between negative affect and bulimic behaviors during the EMA period. Overall, the findings suggest that habit may play a role in maintaining binge eating and purging.
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- Title
- ENGAGEMENT FRAMEWORK FOR SERIOUS THERAPEUTIC GAMES FOR HEALTH
- Creator
- Damarjian, Alex G.
- Date
- 2022
- Description
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The conventional treatment of amblyopia in pediatric patients routinely experience low patient compliance due toits limitations. Therapeutic...
Show moreThe conventional treatment of amblyopia in pediatric patients routinely experience low patient compliance due toits limitations. Therapeutic games that utilize VR technology have the potential to open new avenues of medical research and treatment. A review of the prevailing literature shows the effectiveness of VR based games for therapeutic applications and the potential for increased patient compliance. A strong component of the literature is grounded in the medical humanities, specifically the way in which thought patterns, cognitive development, and perceived social rejection affect patient engagement and treatment efficacy. In order to increase the effectiveness of therapeutic games and streamline their development, a new framework has been created using existing research into therapeutic games. This framework ensures that all therapeutic games meet certain criteria within ethics, immersion, active learning, universal accessibility, aesthetics, and medicine. When applied to game development, specifically virtual and extended reality games, it can be used to transform existing therapeutic or diagnostic models into games operating as health care tools. The result is a more effective, lower cost, more accessible treatment option with increased patient compliance and greater overall outcomes.
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- Title
- DOES FAMILY QUALITY OF LIFE MEDIATE THE RELATION BETWEEN AUTISM WAIVER SERVICES AND CHILD PROGRESS?
- Creator
- Desai, Shivani S.
- Date
- 2022
- Description
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Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder that affects a child’s language, social, and behavioral development,...
Show moreAutism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder that affects a child’s language, social, and behavioral development, and also is associated with difficulty with academics, independent completion of daily living skills, and emotion regulation. Diagnosed individuals often require comprehensive, long-term, and family-based intervention that is costly. Several states, including Maryland, have adopted Medicaid Home and Community Based Services (HCBS) waiver services that specifically serve children and young adults with ASD at no out-of-pocket cost to families. The Maryland autism waiver (AW) also includes services to support diagnosed individuals’ family members, including family consultation and respite services. Family factors, such as specific parenting behaviors and parental mental health, contribute significantly to symptom improvement in children with ASD and child development more broadly, highlighting the importance of studying family systems and targeting them in treatment. Prior research has found that AW services have a positive impact on family quality of life (FQoL), which is a multidimensional concept of family functioning. The aim of the present study was to examine if the several domains of FQoL are mediators in the relation between receipt of Maryland HCBS AW services and caregivers’ perception of their child’s improvement in several domains of functioning. The participants in this study consisted of 460 families who were enrolled in a larger study examining effects of Maryland AW services. Half of these families (n = 230) received the Maryland Medicaid AW services (n = 230) and the other half were on a registry to receive services (n = 230). Deidentified survey data were collected between 2013-2016 from caregiver informants who had a child under the age of 21 who exhibited symptoms of ASD. The survey included questions about demographics, FQoL, and their child’s progress in the areas of academics, independent living skills, social communication skills, stereotypic and repetitive behaviors, and aggressive behaviors over the past 6 months. Results of the mediation analyses revealed that FQoL in the domains of parenting, emotional well-being, and disability support services (but not in the domains of family interaction and physical/material well-being) each mediated the relations between AW services and caregiver report of improvement in all measured domains of child functioning (academics, independent living skills, social communication skills, stereotypic and repetitive behaviors, and aggressive behaviors). These findings highlight the significant role of FQoL as a mediator in the relation between waiver serves and child outcome. They also reveal the importance of increasing family quality of life when providing treatment services to children with symptoms of autism and their families.
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- Title
- WIDE BANDGAP FRACTIONAL POWER PROCESSING
- Creator
- Kundu, Aritra
- Date
- 2022
- Description
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The adoption of wide bandgap (WBG) power semiconductors can improve the performance of power converters at the expense of significantly higher...
Show moreThe adoption of wide bandgap (WBG) power semiconductors can improve the performance of power converters at the expense of significantly higher cost than Si at present time. In this thesis, an innovative Wide bandgap Fractional Power Processing (WFPP) design concept is introduced where silicon devices process the base power at a low switching frequency (2kHz or lower) while WBG devices are judiciously used to process only a fraction of the total power at a much higher frequency (tens of kHz). WFPP inverter is a design concept that splits the power processing into a low frequency Si base power processor and a high-frequency WBG fractional power processor. WBG devices are therefore judiciously used to process only a fraction of the total power to achieve both high-efficiency and lower cost than a full-WBG converter design. This thesis investigates an optimization strategy to minimize the total power loss while maintaining a reasonable THD and cost for a hybrid inverter design with comprehensive power loss analysis and calculation on fundamental and harmonics currents. Optimal selection of power sharing between the Si and WBG inverters and switching frequency are discussed in the thesis. The circulating current paths in topology with hybrid switching frequencies are also analyzed and presented in this thesis. Experimental results on a 9kW SiC/Si hybrid inverter prototype with isolated and non-isolated DC power supplies are presented to validate the design concept.
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- Title
- STRUCTURE AND DYNAMICS OF MODIFIED NUCLEOSOMES UNDER EPIGENETIC REGULATION
- Creator
- Kohestani, Havva
- Date
- 2022
- Description
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Epigenetic regulations are critical in inducing heritable phenotype changes in biological systems without alternating their core genetic DNA...
Show moreEpigenetic regulations are critical in inducing heritable phenotype changes in biological systems without alternating their core genetic DNA sequences. In vivo, reversible epigenetic mechanisms engage various molecular structures from RNAs to larger proteins. The present thesis investigates the influence of epigenetic regulatory factors such as histone protein variants and small non-coding RNAs on the dynamics and structure of nucleosome core particles. Our results show that a histone substitution is an efficient tool in increasing or decreasing the exposure of DNA to post-translational modification (PTMs) factors or larger molecular assembly elements. Substitution of canonical H2A with H2A.B alters DNA-dimer interface resulting in increased breathing and accessibility of DNA. Replacement of canonical H3 with CENP-A variant impacts the overall core-DNA dynamics with flexibility of DNA entry/ exit sites and more rigid tetramer structure. Histone substitution also affects the micro to macro level molecular communication in the nucleosome system. The long-range correlated motions are weakened in H2A.B compared to canonical NCP. We observed a reduction in effective long-range DNA-DNA and DNA-core allosteric pathways in CENP-A NCP compared to canonical and Widom NCPs. Non-coding RNAs increase the tendency of the H3 tail histones to interact with DNA and induce the structural changes in the initial ideal B-DNA of NCP. Overall, the interaction of epigenetic regulatory factors in the form of protein or nucleic acids shifts the energetic and structural properties of the original nucleosome system. As a result, the chromatin structure is prepared to generate the proper biological response throughout spermatogenesis, chromosome segregation, or PTMs assembly.
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- Title
- PREDICTING AND SIMULATING OUTDOOR THERMAL COMFORT-BASED HUMAN BEHAVIOR IN URBAN ENVIRONMENTS
- Creator
- Khan, Zahida Marzaban
- Date
- 2022
- Description
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Rapid urban growth due to a constant rise in world population has amplified the need for sustainable design development of cities. Human...
Show moreRapid urban growth due to a constant rise in world population has amplified the need for sustainable design development of cities. Human behavior, a key performance metric of sustainable design, can be rewarding for urban policies and city planning. Due to its complex nature, human behavior prediction and simulation are increasingly challenging. Complexity is associated with multiple factors, among which social and environmental factors are critical, especially in urban conditions with tall buildings that create unique microclimates. Human behavior in this study referred to human spatial behavior. This research hypothesized that the microclimatic variations at seasonal and diurnal levels affect people’s behavior in outdoor urban environments. Additionally, interdisciplinary crossover studies on novel methodologies to predict human behavior is becoming popular. Moreover, architects and urban designers are interested in human behavior simulation tools that can help them make informed design decisions through ‘what-if’ scenarios and assess their designs before execution. This doctoral research investigated the inter-relationship between Outdoor Thermal Comfort (OTC), human behavior, and urban morphology for Plazas in urban conditions with tall buildings and within a specific climate zone. The study focused on two overarching objectives: (1) to present a novel research methodology to investigate and predict OTC-based human behavior in urban conditions; and (2) to develop HuBeSIM - a human behavior simulation framework using an agent-based model (ABM) to simulate OTC integrated human behavior in outdoor spaces. Daley Plaza – an urban public space built-in 1965 in downtown Chicago — was used as (1) a case study to test the feasibility of this research methodology and (2) a pilot study to demonstrate the HuBeSIM framework. The outcome of this study shows a significant impact in the outdoor urban environments with design goals that use human behavior as a key performance indicator. The research contributes to the modeling and simulation of OTC-based human behavior in urban environments to nurture livable communities and sustainable cities. The first part of the dissertation presented a novel research methodology involving data collection through an on-site observational study for behavioral mapping, and microclimatic CFD simulations for OTC index - Physiological Equivalent Temperature (PET). The sample data consisted of two seasons, namely summer and fall, with more than 600 observations collected during the three-hour lunchtime period. The second part of the dissertation involved developing a Human Behavior SIMulation (HuBeSIM) framework in the popular computer aided design platform Rhino® and Grasshopper® (GH). This part integrated OTC using physics-based modeling and human behavior using mathematical agent-based modeling to develop a simulation framework for outdoor urban space design. The findings from the observational study revealed a moderate relationship between microclimate and human behavior in the fall, and a weak correlation in summer. The results showed that people’s behavior is not affected by PET values above 35°C. The proposed Human Behavior SIMulation framework has a high potential to develop into a comprehensive model by incorporating other behavioral factors. This study contributes to the sustainable built environment design that leads to the environmental, social, and economic upliftment of a city.
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- Title
- The Feasibility of Double-Skin Façades to Provide Natural Ventilation in Tall Office Buildings
- Creator
- Kim, Yohan
- Date
- 2022
- Description
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Many tall office buildings (i.e., buildings of or taller than 656 ft (200 m)) are on the rise around the world. The energy efficiency and...
Show moreMany tall office buildings (i.e., buildings of or taller than 656 ft (200 m)) are on the rise around the world. The energy efficiency and healthy environment of tall office buildings has become an important concern, given the current environmental challenges and health considerations. Natural ventilation has proven to be an effective passive strategy in improving energy efficiency and providing healthy environments given environmental challenges. However, such a strategy has not been commonly adopted to tall office buildings that traditionally rely on single-skin façades (SSFs), due to the high wind pressure that creates excessive air velocities and occupant discomfort at upper floors. Double-skin façades (DSFs) can provide an opportunity to facilitate natural ventilation in tall office buildings, as the fundamental components such as the additional skin and openings create a buffer to regulate the direct impact of wind pressure and the airflow around the buildings. Wind-driven natural ventilation has not been fully studied in DSFs as most previous studies focused on the stack effect. Moreover, the studies assumed that the indoor spaces are mechanically ventilated without regard to airflow behavior between the air cavities and the indoor spaces. This study investigates the impact of modified multi-story type DSFs on indoor airflow in a 60-story, 780-foot (238 m) naturally ventilated tall office building under isothermal conditions. Therefore, the performance of wind effect related components was assessed based on the criteria (e.g., air velocity and airflow distribution), with respect to opening size, number of openings per floor, cavity depth, and cavity segmentation. Computational fluid dynamics (CFD) software was utilized to simulate outdoor airflow around the tall office building, and indoor airflow at various heights in case of various DSF configurations. Two sequential CFD simulations were carried out not only to reduce computational time, but also to comprehensively analyze the impact of DSFs responding to positive and negative wind pressures on indoor airflow behavior. The CFD simulation results indicate that the outer skin opening is the more influential parameter than the others on indoor airflow behavior. On the other hand, variations of inner skin opening size help improve the indoor airflow, with respect to the desired air velocity and distributions. Despite some air vortexes observed in the indoor spaces, cross ventilation can occur as positive pressure on the windward side and negative pressure on the other sides generate a productive pressure differential. The results also demonstrate that DSFs with smaller openings suitably reduce not only the impact of wind pressure, but also the concentration of high air velocity near the windows on the windward side, compared to single-skin façades. Further insight on indoor airflow behaviors depending on various DSF configurations leads to a better understanding of the DSF design strategies for effective natural ventilation in tall office buildings. This study aims to develop a performance-based DSF design guideline to assist architects in their design of DSF components in the early design stage.
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- Title
- THE RELATIONSHIP BETWEEN SLUGGISH COGNITIVE TEMPO AND PERFORMANCE ON TASKS OF PROCESSING SPEED: INFLUENCE OF DEPRESSION
- Creator
- Kim, Jeong Hye
- Date
- 2021
- Description
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Sluggish cognitive tempo (SCT) is often associated with reported difficulties in various functional areas, including daily activities,...
Show moreSluggish cognitive tempo (SCT) is often associated with reported difficulties in various functional areas, including daily activities, emotional functioning, cognitive functioning, academic performance, and sleep. However, there are only a handful of research studies on SCT and neurocognitive functioning in adult populations, and the neuropsychological profile of SCT in adults is unclear.The purpose of this research is to investigate the effect of depression on the relationship between a self-reported measure of SCT and objective measures of SCT in adults by focusing on processing speed performance. The result of this research supports the previous notion that SCT is a novel and independent condition distinct from ADHD, and there are significantly positive relationships between symptoms of SCT and Inattention and Hyperactivity/Impulsivity. Furthermore, SCT and depression are also positively associated indicating the people who experience more symptoms of SCT report more symptoms of depression. However, results did not support the hypothesis that SCT significantly contribute to differences in performance on various types of neuropsychological tasks (WAIS PSI, Trail Making Test, and CPT-II Reaction Time) assessing processing speed after controlling for symptoms of ADHD (inattention and hyperactivity/impulsivity) and symptoms of depression. It is notable that the significant model beta weights for SCT in the final regression model suggests that the relationship between SCT and processing speed is worthy of additional investigation.
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- Title
- MULTICRITERIA DECISION-MAKING METHODOLOGY WITH TRADEOFF ANALYSIS FOR TRANSPORTATION BUDGET ALLOCATION
- Creator
- Truong, Tung Quoc
- Date
- 2022
- Description
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Transportation agencies in the United States nowadays rely on tax dollars for maintaining surface transportation infrastructure, which mainly...
Show moreTransportation agencies in the United States nowadays rely on tax dollars for maintaining surface transportation infrastructure, which mainly comes from fuel tax. However, travel behaviors are changing every day. People and businesses demand better and safer roads. Yet, consumers travel in more fuel-efficient vehicles and buy less gas, which means less revenue for fixing aging roads and highways. Meanwhile, new construction and repair costs increase for our overburdened transportation systems. Transportation agencies, therefore, must use their limited funding more wisely to optimize the service performance and minimize risks (Li, 2018). The budget allocation problem in transportation is not an easy task. The consequences of an ineffective decision in allocating resources are multi-facet both in the short- and long-term, including degrading in the condition of transportation facilities, losing public trust, and increasing backlogs in maintenance and repair. Therefore, transportation agencies are seeking more robust and comprehensive data-driven strategies that take into account of agency’s strategic goals and regulatory requirements, user expectations, nature of the asset, availability of resources, and lifecycle cost analysis in determining the optimal allocation of resources and making the best use of available funds (Li and Sinha, 2004; Sinha and Labi, 2007). The proposed research aims to utilize the concept of multicriteria decision making coupled with a holistic asset management framework to support performance-based allocations of transportation budgets and help transportation agencies achieve the future vision of the nation’s strategic planning requirements to enable sustainable management of the system. A computational study for the real-world dataset obtained by a state Department of Transportation (DOT) is conducted using the proposed budget allocation method. The results from the computational study reveal that the proposed method can derive optimal decision solutions for transportation budget allocation problems and can be utilized by transportation agencies on different scales – urban and rural, in other sectors – public and private, to effectively manage the transportation infrastructure sustainably, by effectively spending transportation budget to maximize service performance and minimize operating costs.
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