Search results
(9,801 - 9,820 of 10,079)
Pages
- Title
- Spraying Process
- Creator
- Bradstreet, Samuel W., Griffith, James S.
- Date
- 1956-09-18
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- X-Ray Source
- Creator
- Reiffel, Leonard
- Date
- 1957-06-25
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Electromagnetic Transducer Head
- Creator
- Camras, Marvin
- Date
- 1957-08-20
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Magnetic Recorder
- Creator
- Camras, Marvin
- Date
- 1958-10-21
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Doing physics : a festschrift for Thomas Erber
- Date
- 2010, 2010
- Publisher
- IIT Press, Chicago, IL
- Description
-
Doing Physics is a festschrift (collection of articles, essays, and rememberances) published in honor of Illinois Tech Physics professor...
Show moreDoing Physics is a festschrift (collection of articles, essays, and rememberances) published in honor of Illinois Tech Physics professor Thomas Erber's 80th birthday. Selections were authored by Erber's colleagues, former stduents, and fellow scholars. This book was released in print form, this file was the original pdf assembled by editor Porter Johnson and submitted for printing with the front and rear covers added.
Show less
- Title
- Optimizing Cell-Free Protein Synthesis for Increased Yield and Activity of Colicins
- Date
- 2019,
- Publisher
- MDPI
- Description
-
Colicins are antimicrobial proteins produced by Escherichia coli that hold great promise as viable complements...
Show moreColicins are antimicrobial proteins produced by Escherichia coli that hold great promise as viable complements or alternatives to antibiotics. Cell-free protein synthesis (CFPS) is a useful production platform for toxic proteins because it eliminates the need to maintain cell viability, a common problem in cell-based production. Previously, we demonstrated that colicins produced by CFPS based on crude Escherichia coli lysates are e?ective in eradicating antibiotic-tolerant bacteria known as persisters. However, we also found that some colicins have poor solubility or low cell-killing activity. In this study, we improved the solubility of colicin M from 16% to nearly 100% by producing it in chaperone-enriched E. coli extracts, resulting in enhanced cell-killing activity. We also improved the cytotoxicity of colicin E3 by adding or co-expressing the E3 immunity protein during the CFPS reaction, suggesting that the E3 immunity protein enhances colicin E3 activity in addition to protecting the host strain. Finally, we con?rmed our previous ?nding that active colicins can be rapidly synthesized by observing colicin E1 production over time in CFPS. Within three hours of CFPS incubation, colicin E1 reached its maximum production yield and maintained high cytotoxicity during longer incubations up to 20 h. Taken together, our ?ndings indicate that colicin production can be easily optimized for improved solubility and activity using the CFPS platform.
Sponsorship: NIH R15AI130988
Show less
- Title
- Editorial, "Cell-Free Synthetic Biology": Synthetic Biology Meets Cell-Free Protein Synthesis
- Date
- 2019,
- Publisher
- MDPI
- Description
-
Sponsorship: NIH R15AI130988
- Title
- Leveraging the flexibility of Islandora to create a dual-use digital repository
- Date
- 2021, 2021
- Publisher
- Henry Stewart Publications
- Collection
- Journal of Digital Media Management
- Title
- German Spritzdekor Ceramics, 1928-1936: A Degenerate Art
- Date
- 2018
- Publisher
- IIT Press
- Description
-
An exhibition catalog for an exhibit housed in Galvin Library's Kemper Gallery from April to Septmeber, 2017. The exhibition was comprised of...
Show moreAn exhibition catalog for an exhibit housed in Galvin Library's Kemper Gallery from April to Septmeber, 2017. The exhibition was comprised of German airbrushed ceramics from the collection of Maral and Rolf Achilles. Ghazal Hashemi designed the Spritzdekor web site and this pdf catalog. All photographs are by Allen Bourgeois.
Sponsorship: Funding for this catalog was provided by grants from the Walter and Karla Goldschmidt Foundation and Richard H. Driehaus.
Show less
- Title
- Estimation for Dyadic-Dependent Exponential Random Graph Models
- Date
- 2014, 2014-04-30
- Description
-
Graphs are the primary mathematical representation for networks, with nodes or vertices corresponding to units (e.g., individuals) and edges...
Show moreGraphs are the primary mathematical representation for networks, with nodes or vertices corresponding to units (e.g., individuals) and edges corresponding to relationships. Exponential Random Graph Models (ERGMs) are widely used for describing network data because of their simple structure as an exponential function of a sum of parameters multiplied by their corresponding sufficient statistics. As with other exponential family settings the key computational difficulty is determining the normalizing constant for the likelihood function, a quantity that depends only on the data. In ERGMs for network data, the normalizing constant in the model often makes the parameter estimation intractable for large graphs, when the model involves dependence among dyads in the graph. One way to deal with this problem is to approximate the likelihood function by something tractable, e.g., by using the method of pseudo-likelihood estimation suggested in the early literature. In this paper, we describe the family of ERGMs and explain the increasing complexity that arises from imposing different edge dependence and homogeneous parameter assumptions. We then compare maximum likelihood (ML) and maximum pseudo-likelihood (MPL) estimation schemes with respect to existence and related degeneracy properties for ERGMs involving dependencies among dyads.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Generic Identification of Binary-Valued Hidden Markov Processes
- Date
- 2014, 2014-04-30
- Description
-
The generic identification problem is to decide whether a stochastic process (X_t) is a hidden Markov process and if yes to infer its...
Show moreThe generic identification problem is to decide whether a stochastic process (X_t) is a hidden Markov process and if yes to infer its parameters for all but a subset of parametrizations that form a lower-dimensional subvariety in parameter space. Partial answers so far available depend on extra assumptions on the processes, which are usually centered around stationarity. Here we present a general solution for binary-valued hidden Markov processes. Our approach is rooted in algebraic statistics hence it is geometric in nature. We find that the algebraic varieties associated with the probability distributions of binary-valued hidden Markov processes are zero sets of determinantal equations which draws a connection to well-studied objects from algebra. As a consequence, our solution allows for algorithmic implementation based on elementary (linear) algebraic routines.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Binary hidden Markov models and varieties, AS2012 Special Volume, part 2: This issue includes a second series of papers from talks, posters and collaborations resulting from and inspired by the Algebraic Statistics in the Alleghenies Conference at Penn State, which took place in July 2012.
- Date
- 2013, 2013
- Description
-
This paper closely examines HMMs in which all the hidden random variables are...
Show moreThis paper closely examines HMMs in which all the hidden random variables are binary. Its main contributions are (1) a birational parametrization for every such HMM, with an explicit inverse for recovering the hidden parameters in terms of observables, (2) a semialgebraic model membership test for every such HMM, and (3) minimal dening equations for the 4-node fully binary model, comprising 21 quadrics and 29 cubics, which were computed using Grobner bases in the cumulant coordinates of Sturmfels and Zwiernik. The new model parameters in (1) are rationally identiable in the sense of Sullivant, Garcia-Puente, and Spielvogel, and each model's Zariski closure is therefore a rational projective variety of dimension 5. Grobner basis computations for the model and its graph are found to be considerably faster using these parameters. In the case of two hidden states, item (2) supersedes a previous algorithm of Schonhuth which is only generically dened, and the dening equations (3) yield new invariants for HMMs of all lengths 4. Such invariants have been used successfully in model selection problems in phylogenetics, and one can hope for similar applications in the case of HMMs.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Learning Coefficient in Bayesian Estimation of Restricted Boltzmann Machine, AS2012 Special Volume, part 2: This issue includes a second series of papers from talks, posters and collaborations resulting from and inspired by the Algebraic Statistics in the Alleghenies Conference at Penn State, which took place in July 2012.
- Date
- 2013, 2013
- Description
-
We consider the real log canonical threshold for the learning model in Bayesian estimation. This threshold corresponds to a learning...
Show moreWe consider the real log canonical threshold for the learning model in Bayesian estimation. This threshold corresponds to a learning coefficient of generalization error in Bayesian estimation, which serves to measure learning efficiency in hierarchical learning models [30, 31, 33]. In this paper, we clarify the ideal which gives the log canonical threshold of the restricted Boltzmann machine and consider the learning coefficients of this model.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- The precision space of interpolatory cubature formulæ
- Date
- 2015, 2015-06-11
- Description
-
Methods from Commutative Algebra and Numerical Analysis are combined to address a problem common to many disciplines: the estimation of the...
Show moreMethods from Commutative Algebra and Numerical Analysis are combined to address a problem common to many disciplines: the estimation of the expected value of a polynomial of a random vector using a linear combination of a finite number of its values. In this work we remark on the error estimation in cubature formulæ for polynomial functions and introduce the notion of a precision space for a cubature rule.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- The degeneration of the Grassmannian into a toric variety and the calculation of the eigenspaces of a torus action
- Date
- 2015, 2015-06-11
- Description
-
Using the method of degenerating a Grassmannian into a toric variety, we calculate formulas for the dimensions of the eigenspaces of the...
Show moreUsing the method of degenerating a Grassmannian into a toric variety, we calculate formulas for the dimensions of the eigenspaces of the action of an n-dimensional torus on a Grassmannian of planes in an n-dimensional space.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Varieties with maximum likelihood degree one
- Date
- 2014, 2014-04-30
- Description
-
We show that algebraic varieties with maximum likelihood degree one are exactly the images of reduced A-discriminantal varieties under...
Show moreWe show that algebraic varieties with maximum likelihood degree one are exactly the images of reduced A-discriminantal varieties under monomial maps with finite fibers. The maximum likelihood estimator corresponding to such a variety is Kapranov’s Horn uniformization. This extends Kapranov’s characterization of A-discriminantal hypersurfaces to varieties of arbitrary codimension.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Maximum Likelihood for Matrices with Rank Constraints
- Date
- 2014, 2014-04-30
- Description
-
Maximum likelihood estimation is a fundamental optimization problem in statistics. We study this problem on manifolds of matrices with bounded...
Show moreMaximum likelihood estimation is a fundamental optimization problem in statistics. We study this problem on manifolds of matrices with bounded rank. These represent mixtures of distributions of two independent discrete random variables. We determine the maximum likelihood degree for a range of determinantal varieties, and we apply numerical algebraic geometry to compute all critical points of their likelihood functions. This led to the discovery of maximum likelihood duality between matrices of complementary ranks, a result proved subsequently by Draisma and Rodriguez.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- Uncovering Proximity of Chromosome Territories using Classical Algebraic Statistics
- Date
- 2015, 2015-11-09
- Description
-
Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments...
Show moreExchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with fragments from other chromosomes or from other regions within the same chromosome. ETCAs are commonly observed in cancer cells and in cells exposed to radiation. The frequency of these chromosome rearrangements is correlated with their spatial proximity, therefore it can be used to infer the three dimensional organization of the genome. Extracting statistical significance of spatial proximity from cancer and radiation data has remained somewhat elusive because of the sparsity of the data. We here propose a new approach to study the three dimensional organization of the genome using algebraic statistics. We test our method on a published data set of irradiated human blood lymphocyte cells. We provide a rigorous method for testing the overall organization of the genome, and in agreement with previous results we find a random relative positioning of chromosomes with the exception of the chromosome pairs {1,22} and {13,14} that have a significantly larger number of ETCAs than the rest of the chromosome pairs suggesting their spatial proximity. We conclude that algebraic methods can successfully be used to analyze genetic data and have potential applications to larger and more complex data sets.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- A linear-algebraic tool for conditional independence inference
- Date
- 2015, 2015-11-09
- Description
-
In this note, we propose a new linear-algebraic method for the implication problem among conditional independence statements, which is...
Show moreIn this note, we propose a new linear-algebraic method for the implication problem among conditional independence statements, which is inspired by the factorization characterization of conditional independence. First, we give a criterion in the case of a discrete strictly positive density and relate it to an earlier linear-algebraic approach. Then, we extend the method to the case of a discrete density that need not be strictly positive. Finally, we provide a computational result in the case of six variables.
Show less - Collection
- Journal of Algebraic Statistics
- Title
- A Family of Quasisymmetry Models
- Date
- 2015, 2015-06-11
- Description
-
We present a one-parameter family of models for square contingency tables that interpolates between the classical quasisymmetry model and its...
Show moreWe present a one-parameter family of models for square contingency tables that interpolates between the classical quasisymmetry model and its Pearsonian analogue. Algebraically, this corresponds to deformations of toric ideals associated with graphs. Our discussion of the statistical issues centers around maximum likelihood estimation.
Show less - Collection
- Journal of Algebraic Statistics
