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Title: Undecanoic Acid, Lauric Acid, and N-Tridecanoic Acid Inhibit Escherichia coli Persistence and Biofilm Formation
Creator: Jin, Xing, Zhou, Jiacheng, Richey, Gabriella, Wang, Mengya, Hong, Sung Min Choi, Hong, Seok Hoon
Date: 2021
Description: Persister cell formation and biofilms of pathogens are extensively involved in the development of chronic infectious diseases. Eradicating...
Show morePersister cell formation and biofilms of pathogens are extensively involved in the development of chronic infectious diseases. Eradicating persister cells is challenging, owing to their tolerance to conventional antibiotics, which cannot kill cells in a metabolically dormant state. A high frequency of persisters in biofilms makes inactivating biofilm cells more difficult, because the biofilm matrix inhibits antibiotic penetration. Fatty acids may be promising candidates as antipersister or antibiofilm agents, because some fatty acids exhibit antimicrobial effects. We previously reported that fatty acid ethyl esters effectively inhibit Escherichia coli persister formation by regulating an antitoxin. In this study, we screened a fatty acid library consisting of 65 different fatty acid molecules for altered persister formation. We found that undecanoic acid, lauric acid, and N-tridecanoic acid inhibited E. coli BW25113 persister cell formation by 25-, 58-, and 44-fold, respectively. Similarly, these fatty acids repressed persisters of enterohemorrhagic E. coli EDL933. These fatty acids were all medium-chain saturated forms. Furthermore, the fatty acids repressed Enterohemorrhagic E. coli (EHEC) biofilm formation (for example, by 8-fold for lauric acid) without having antimicrobial activity. This study demonstrates that medium-chain saturated fatty acids can serve as antipersister and antibiofilm agents that may be applied to treat bacterial infections.
Sponsorship: NIH-R15AI130988; NSF REU-1757989
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Title: Priming Movie Product Placements: New Insights from a Cross-National Case Study
Creator: Balasubramanian,Siva K, Gistri, Giacomo
Date: 44354, 44327
Publisher: Taylor & Francis
Description: The paucity of research on priming product placements and insights from practitioners (Study 1) motivated our investigation into how and when...
Show moreThe paucity of research on priming product placements and insights from practitioners (Study 1) motivated our investigation into how and when priming works in movie placements. Study 2 explores the impact of media priming (a media story announcing a movie placement before the movie’s release) and ad priming (a similar ad announcement) on recall through contrasts with no priming (control). US students watched a movie in a theatre after such priming for a subtle or a prominent placement. When compared to no priming, both media priming and ad priming enhanced recall for the subtle placement; no difference in recall performance emerged between no priming and either type of priming for the prominent placement. Contrast tests comparing media priming and ad priming indicated no differences in recall for either subtle or prominent placement. Study 3 replicated these recall findings with Italian moviegoers, and supported additional hypotheses and propositions for brand attitude. For the subtle (prominent) placement, attitude did not change (decreased) when comparing either media priming or ad priming with no priming. Contrast tests comparing media priming and ad priming indicated no differences in attitude outcomes, for either subtle or prominent placement. Using no priming as a baseline for comparison, the converging conclusion is that any type of priming improves (does not change) recall and does not change (worsens) attitude for subtle (prominent) placements. Overall, results do not support priming for prominent placements; selective use of any type of priming for subtle placements appears appropriate to improve recall outcomes.
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Collection: International Journal of Advertising

Title: Some Paradoxes of Whistleblowing
Creator: Davis, Michael
Date: 2006, 1996
Publisher: Philosophy Documentation Center
Description: By "paradox" I mean an apparent- and in this case, real-inconsistency between theory (our systematic understanding of whistleblowing) and the...
Show moreBy "paradox" I mean an apparent- and in this case, real-inconsistency between theory (our systematic understanding of whistleblowing) and the facts (what we actually know, or think we know, about whistleblowing). What concerns me is not a few anomalies, the exceptions that test a rule, but a flood of exceptions that seem to swamp the rule. This paper has four parts. The first states the standard theory of whistleblowing. The second argues that the standard theory is paradoxical, that it is inconsistent with what we know about whistleblowers. The third part sketches what seems to me a less paradoxical theory of whistleblowing. The fourth tests this new theory against one classic case of whistleblowing, Roger Boisjoly's testimony before the presidential commission investigating the Challenger disaster (the "Rogers Commission"). I use that case because the chief facts are both uncontroversial enough and well-known enough to make detailed exposition unnecessary. For the same reasons, I also use that case to illustrate various claims about whistleblowing throughout the paper.
Business and Professional Ethics Journal, Vo. 15, No.1. pp.3-19.
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Title: “Broader Impacts” or “Responsible Research and Innovation”? A Comparison of Two Criteria for Funding Research in Science and Engineering
Creator: Davis, Michael, Laas, Kelly
Date: 2013-10, 2013-10
Publisher: Springer
Description: Our subject is how the experience of Americans with a certain funding criterion, “broader impacts” (and some similar criteria) may help in...
Show moreOur subject is how the experience of Americans with a certain funding criterion, “broader impacts” (and some similar criteria) may help in efforts to turn the European concept of Responsible Research and Innovation (RRI) into a useful guide to funding Europe’s scientific and technical research. We believe this comparison may also be as enlightening for Americans concerned with revising research policy. We have organized our report around René Von Schomberg’s definition of RRI, since it seems both to cover what the European research group to which we belong is interested in and to be the only widely accepted definition of RRI. According to Von Schomberg, RRI: “… is a transparent, interactive process by which societal actors and innovators become mutually responsive to each other with a view to the (ethical) acceptability, sustainability and societal desirability of the innovation process and its marketable products (in order to allow a proper embedding of scientific and technological advances in our society).” While RRI seeks fundamental changes in the way research is conducted, Broader Impacts is more concerned with more peripheral aspects of research: widening participation of disadvantaged groups, recruiting the next generation of scientists, increasing the speed with which results are used, and so on. Nevertheless, an examination of the broadening of funding criteria over the last four decades suggests that National Science Foundation has been moving in the direction of RRI.
Sponsorship: European Community’s Seventh Framework Programme grant number 321400.
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Title: The City in the Landscape: Alfred Caldwell's Broader Perspective on Urban Design
Creator: Jones, Kristin, Garcia-Requejo, Zaida
Date: 2020, 2020
Publisher: Editorial Universitat Politècnica de València
Description: Alfred Caldwell was among the first full- time American professors Mies van der Rohe hired at the Illinois Institute of Technology (IIT). Many...
Show moreAlfred Caldwell was among the first full- time American professors Mies van der Rohe hired at the Illinois Institute of Technology (IIT). Many have admired Mies’s architecture since the 1920s, and know that his ideas were also transmitted as a professor, first at the Bauhaus in Europe and then as Director of the Department of Architecture at IIT. Caldwell, a practicing landscape architect and protégé of Jens Jensen, is perhaps less widely known, but was a major influence on IIT’s program especially in the areas of construction, landscape, and architectural history. Caldwell completed a Master of Science in City Planning with a thesis entitled The City in the Landscape: A Preface for Planning, which can be considered a manifesto of both his professional ideas and IIT’s planning pedagogy. In addition to his own works, Caldwell collaborated with Mies and architect Ludwig Hilberseimer, Director of City and Regional Planning at IIT and former Head of Building Theory at the Bauhaus, on the design of built works which left behind artifacts representing the ideal of “the city in the landscape.” This communication examines the broader perspective on urban design influenced by the symbiotic disciplines of architecture, city-regional planning and landscape as manifested in the individual and collaborative built work and pedagogy of Caldwell, Hilberseimer, and Mies.
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Collection: EAAE-ARCC International Conference & 2nd Valencia International Biennial

Title: From positivism to conventionalism: Comte, Renouvier, and Poincaré
Creator: Schmaus, Warren
Date: 2019, 2019
Publisher: Elsevier

Title: A Gröbner Basis Database
Creator: Mojsilović, Jelena
Date: 2022

Title: Stephen Fienberg's influence on algebraic statistics, Special Volume in honor of memory of S.E.Fienberg
Creator: Petrović, Sonja, Slavkovic, Aleksandra, Yoshida, Ruriko
Date: 2019, 2019-04-12
Description: Stephen (Steve) E. Fienberg (1942-2016) was an eminent statistician, whose impact on research, education and the practice of statistics, and...
Show moreStephen (Steve) E. Fienberg (1942-2016) was an eminent statistician, whose impact on research, education and the practice of statistics, and many other fields is astonishing in its breadth. He was a visionary when it came to linking many different areas to address real scientific issues. He professed the importance of statistics in many disciplines, but recognized that true interdisciplinary work requires joining of the expertise across different areas, and it is in this spirit that he helped steer algebraic statistics toward becoming a thriving subject. Many of his favorite topics in the area are covered in this special issue. We are grateful to all authors for contributing to this volume to honor him and his influence on the field. During the preparation of this issue, we learned about the tragic killing of his widow, Joyce Fienberg, during the Tree of Life Synagogue massacre in Pittsburgh, PA on October 27, 2018. This issue is dedicated to their memory.
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Collection: Journal of Algebraic Statistics