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Title: Initiating Strategies for Urbanization and Housing Patterns
Creator: Rehan, Natale
Date: 2010-07-30

Title: Tests on Kerr steam turbine and direct-connected Worthington centrifugal pump
Creator: James, Sydney Vincent, Jackson, Irving Foster
Date: 2009, 1907
Publisher: Armour Institute of Technology
Description: http://www.archive.org/details/testsonkerrsteam00jame
Thesis (B.S.)--Armour Institute of Technology; Includes index

Title: CO2 CAPTURE AND HYDROGEN PRODUCTION IN SORBENT ENHANCED WATER-GAS SHIFT (SEWGS) PROCESS WITH REGENERABLE SOLID SORBENT
Creator: Zarghami Khanehsar, Shahin
Date: 2015, 2015-07
Description: Carbon dioxide emission from fossil fuel combustion and its impact on global warming is one of the most critical environmental issues nowadays...
Show moreCarbon dioxide emission from fossil fuel combustion and its impact on global warming is one of the most critical environmental issues nowadays. Coal as a main source of produce energy is the most CO2-intensive fossil fuel. Advanced power generation processes that use gasification technology, such as Integrated Gasification Combined Cycle (IGCC), which offer higher efficiency, are among the leading contenders for power generation in the 21st century. In an IGCC process, because of high pressure, carbon dioxide in the fuel gas is at higher concentration, which can be captured and sequestered at lower costs. Utilization of regenerable MgO-based sorbents has been shown to be an effective method for capturing CO2 from gasification-based processes at elevated temperatures and pressures (i.e. p > 20 atm and 330° < T < 450°C). Low cost MgO based sorbent can be prepared through modification of natural dolomite. The reactivity of the sorbent in carbonation/regeneration cycles has a significant impact on the economics of the proposed regenerable process. Although the sorbent can be regenerated in successive cycles, the sorbent reactivity and capacity gradually decline during the cyclic process. Therefore, it is crucial to develop a better understanding on the role of the key parameters affecting the reactivity of the sorbent going through the cyclic carbonation/regeneration process. In this work, a systematic study on the sorbent preparation parameters (i.e., calcination temperature, calcination duration, calcination temperature ramp, potassium concentration, impregnation duration, drying temperature, re-calcination temperature, and re-calcination duration) was conducted to understand the effect of each parameter on the overall capacity and reactivity of the sorbent. The concentration of potassium additive (as carbonation reaction promoter) has the most significant effect on the reactivity of the sorbent and the optimum K/Mg molar ratio appears to be in the range of 0.1-0.16. The reactivity of the sorbent toward carbon dioxide at various operating conditions (i.e. temperature, CO2 concentration and steam concentration) was experimentally evaluated. The presence of steam significantly improves the reactivity of the sorbent which is attributed to formation of more favorable pore structure as well as the existence of a parallel carbonation reaction pathway involving the formation of a transient MgO.H2O* compound. The optimum carbonation reaction temperature in the presence of steam is around 380˚C. The effect of cycling on CO2 capture capacity of MgO-based sorbent was also experimentally investigated in this work. Series of carbonation/regeneration cycles (up to 25) have been carried out in a dispersed bed reactor to determine the effect of various variables on long term durability of the sorbent. The gradual loss of CO2 sorption capacity appears to be mainly due to loss potassium (a carbonation reaction promoter) in the cyclic process. Durability of the sorbents improves in the presence of steam, which is likely due to the favorable changes in the pore structure of the sorbents. A kinetic model was developed to fit the reactivity curves obtained from the dispersed bed tests at different operating conditions which was needed to predict the sorbent/catalyst performance in the regenerative process. Model parameters were defined and discussed for each of the operating conditions, as well as dispersed bed cyclic tests. Furthermore, the thermal behavior and the kinetics of partial decomposition of dolomite were studied in a dispersed-bed reactor to improve the reactivity of the sorbent. The microstructure and the nature of the solid products were found to be strongly dependent on the CO2 partial pressure near the reacting interface and on the decomposition temperature. A significant increase in the rate of the dolomite decomposition reaction was found in the presence of steam. Steam improves the kinetics of decomposition, modifies the radial distribution of the pores; and improves the connectivity of the pores inside the dolomite particles, which decreases the diffusion resistance of produced carbon dioxide inside the particle. A shrinking core model with variable product layer diffusivity was used to fit the experimental data and determine the kinetic parameters of the dolomite decomposition reaction. The results indicate that transport of CO2 across the reacting interface in the porous particle was the main limiting factor in the decomposition reaction at the experimental conditions investigated. A lab-scaled high-pressure/high-temperature packed-bed reactor was utilized to evaluate the performance of the sorbent in simultaneous water-gas shift reaction and sorbent carbonation environment. It was shown that the CO2 in the coal gas can be removed by regenerable MgO-based sorbents at temperatures around 350°C, and the CO2 removal can shift WGS reaction to enhance hydrogen production. Therefore, Sorbent Enhanced Water-Gas-Shift (SEWGS) can result in much higher hydrogen production without lowering the temperature, leading to higher overall process efficiency.
Ph.D. in Chemical Engineering, July 2015
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Title: The Odd Couple: FINAL POSTER
Creator: Bacheller, Tim
Date: 5/4/2011, 2011-05
Description: The socio-political structure of Belgium, a whole containing disparate parts, serves as the catalyst for The Odd Couple: two individual...
Show moreThe socio-political structure of Belgium, a whole containing disparate parts, serves as the catalyst for The Odd Couple: two individual secondary schools in Brussels, one Dutch-speaking, the other French-speaking, sharing the same site. The common element shared among the two schools is the public realm. Rather than shunning the public, the public is encouraged to actively engage in activities within the building. In this way the common spaces throughout the building take on the role of serving the needs and desires of both schools and the public, resulting in the necessity for dialogue and cooperation. By filtering program through a socio-political lens, a “school” typology emerges that emphasizes interaction and extramural learning.
Sponsorship: Conger-Austin, Susan
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Title: Laboratory Notebook 106
Creator: Cooper, Kerri, Lee, Alvin, Slade, Peter
Date: 2010-09-09T21:17:47Z
Description: Validating ozone's optimal conditions on a sucrose food matrix embedded with Bacillus Spores

Title: Criteria for the Existence of Helical Instabilities in Subsonic Inpinging Jets
Creator: Panickar, Praveen, Raman, Ganesh
Date: 2007-10
Publisher: American Inst Physics
Description: Understanding instability modes in impinging jets is important for the design of advanced vertical takeoff and landing aircraft. Our initial...
Show moreUnderstanding instability modes in impinging jets is important for the design of advanced vertical takeoff and landing aircraft. Our initial experimental observations of helical modes in subsonic impinging jets were contrary to expectations based on published stability theory results. This paper focuses on the curious phenomenon of the occurrence of these, hitherto unexpected, helical modes in subsonic impinging jets and provides, both experimental and analytical proof for their existence. Past results, based on linear stability analysis, that call for an absence of helical modes in cold, subsonic impinging jets have been re-examined to reconcile new experimental data. Based on this re-examination, a new threshold Mach number has been proposed, above which helical modes are permissible. The revised theory put forth in this paper indicates that the threshold Mach number for the existence of the helical mode depends on the jet temperature and that this threshold decreases as the jet temperature increases. This threshold Mach number has been experimentally verified for unheated jets. Additionally, the experimental results reveal that the threshold Mach number also depends on the stand-off distance. Finally, it has been shown that the experimentally obtained mean Strouhal numbers for the helical mode show excellent agreement with the Strouhal number of the least dispersive wave of the same mode calculated at various Mach numbers. The results presented here offer hope for better understanding of impinging jet instability modes. (C) 2007 American Institute of Physics.
http://dx.doi.org/10.1063/1.2798804
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Title: IMPACT OF MULTITASKING AND PHYSICAL CONTEXT ON SELF-REPORTED TRANSFER OF E-LEARNING
Creator: Brown, Anna Kirsten
Date: 2015, 2015-05
Description: The growth of e-learning is increasing in todays organizations; however the research to support its application is slow to catch up. Previous...
Show moreThe growth of e-learning is increasing in todays organizations; however the research to support its application is slow to catch up. Previous research has focused on the factors relating to training and transfer of training, there appears to be a dearth on what trainees are actually engaging in during e-learning itself. This study focused on the relationship between di erent types of multitasking on transfer of e-learning and the interrelation of physical distractors in the training environment. Archival data was utilized in the study with 399 participants. The ndings indicate that the number of additional tasks engaged in during training negatively relate to reported transfer of e-learning. Temperature also related to transfer of e-learning. Participants who reported training in a room where they considered the temperature comfortable also noted higher levels of transfer of e-learning. Limitations and suggestions for future research are presented.
M.S. in Psychology, May 2015
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Title: ISOLATION OF TRANSPOSON MEDIATED TRANSGLUTAMINASE MUTANTS OF DROSOPHILA MELANOGASTER
Creator: Yang, Hua
Date: 2016, 2016-05
Description: Transglutaminase, Tg, catalyzes the formation of isopeptide bonds crosslinking and stabilizing protein complexes. The best-known factor XIII...
Show moreTransglutaminase, Tg, catalyzes the formation of isopeptide bonds crosslinking and stabilizing protein complexes. The best-known factor XIII crosslinks fibrin in clots. Paradoxically, there is an unexpected and counterintuitive correlation between factor XIII levels and heart attack mortality. Since factor XIII strengthens fibrin and resists fibrinolysis, higher XIII activity would be expected to lead to more stable fibrin clots and so more fatal atherosclerotic plaques; but it actually results in reduced mortality. One hypothesis to explain this is that Tg activity may also stabilize cardiac muscle tissue. Studies have shown that Tg is expressed in human embryonic myoblasts. Therefore, we suggest that muscular attachments may be strengthened by Tg, and play a vital unrecognized role in the muscular attachment. Humans have 9 Tg genes, complicating studies. However Drosophila melanogaster, D.m., has only one Tg gene, and is an attractive model system. We isolated 39 mutant D.m. lines gene produced by transposon mobilization in locus in a "dirty" fashion expected to create random deletions within the Tg locus. We then characterized them by PCR and sequencing, as well as functional assays, in an attempt to develop a Tg null line to test this hypothesis. The aim is to identify a line with all of Tg removed, but with neighboring genes unperturbed. Once the approximate break points were identified by PCR, we did DNA sequencing to fully characterize the genomic breakpoint. According to the DNA sequencing results, one line is specific for Tg exon1, and eliminates one of the two known Tg transcripts. Another line eliminated almost the entire catalytic domain. We also did RT-qPCR for two lines that were sequenced to determine their genomic characteristics. Both of these lines are viable but with subtle developmental defects, showing that Tg deficiency is not lethal in D.m.
M.S. in Biology, May 2016
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Title: Delta Shelter (sequence unknown), IPRO 311 - Deliverables: IPRO 311 Poster F09
Creator: Schug, Timothy, Bradley, Joshua, Cahan, Noah, Dobbin, Dan, Hallenbeck, Jeff, Jordan, Davyd, Strandquist, Brad, Dohm, Jacob, Hoffman, Kent, Lee, Woong-kyo, Waisath, Nathan
Date: 2009-12
Description: The Delta Tau Delta fraternity wants to make their current house as energy efficient and green as possible. The team will look at all aspects...
Show moreThe Delta Tau Delta fraternity wants to make their current house as energy efficient and green as possible. The team will look at all aspects of the DTD house and their operations to create a more energy efficient fraternity. During the term, the team will consider possible alternatives to many issues including but not limited to: mechanical heating system, building envelope, thermal properties of buildings perimeter, roofing materials, air infiltration, ventilation, and occupancy trends.
Deliverables for IPRO 311: Delta Shelter for the fall 2009
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Title: INCORPORATING REACTIVE POWER MARKET INTO THE DAY-AHEAD ELECTRICITY MARKET
Creator: Al Ghamdi, Mohammed
Date: 2012-05-29, 2012-07
Description: The research work presented in this thesis proposes the incorporation of the reactive power market into the day-ahead electricity market in...
Show moreThe research work presented in this thesis proposes the incorporation of the reactive power market into the day-ahead electricity market in order to compensate generation companies (GENCOs) and independent power producers (IPPs) for providing any additional reactive power support, which varies on an hourly basis based on the load demand, transmission network configuration, and any contingencies that might occur. This proposal would minimize the total payment burden on the independent system operator (ISO), which is related to the reactive power dispatch. The proposed model achieves the main objective of an ISO in a competitive electricity market, which is to provide the required reactive power support from generators at minimum cost while ensuring the secure operation of the power system. In this research, the reactive power price is the bidding-based price that is submitted by the GENCOs and IPPs to the ISOs during the day-ahead market. The proposal takes into the account both the technical and economic aspects associated with the active power and reactive power dispatch in the context of the new operating paradigms in competitive electricity markets. In this research, the Security Constrained Unit Commitment (SCUC) based on AC power flow modeling is considered as the drive engine for clearing the day-ahead electricity market based on the amount of information provided by the market participants. This proposed framework would provide appropriate reactive power support from service providers at minimum cost, while ensuring the secure and reliable operation of the electrical power system. In the research, the PQ capability curves of the generating units are modeled to ensure the practically of the SCUC solutions that are obtained. This proposal would be an essential step toward a fair electricity market while increasing the security of the power system and reducing transmission congestions. Also, it would pave the road for various renewable energy resources since the penetration of renewable energy resources would impact the commitment of the generating units. This would impact the available reactive power reserve margin and security of the network. In addition, incorporating the reactive power market into the day-ahead market would provide a clear signal for optimal private investment in the reactive power capacity. The framework that has been developed is general in nature and can be used for any electricity market structure.
Ph.D. in Electrical Engineering, July 2012
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Title: A study of the corrosion of locomotive boiler tubes
Creator: Congdon, Charles C.
Date: 2009, 1915
Publisher: Armour Institute of Technology
Description: http://www.archive.org/details/studyofcorrosion00cong
Thesis (B.S.)--Armour Institute of Technology; Bibliography: leaves 36-37

Title: INVESTIGATION OF NIOBIUM SURFACE STRUCTURE AND COMPOSITION FOR IMPROVEMENT OF SUPERCONDUCTING RADIO-FREQUENCY CAVITIES
Creator: Trenikhina, Yulia
Date: 2014, 2014-12
Description: Nano-scale investigation of intrinsic properties of niobium near-surface is a key to control performance of niobium superconducting radio...
Show moreNano-scale investigation of intrinsic properties of niobium near-surface is a key to control performance of niobium superconducting radio-frequency cavities. Mechanisms responsible for the performance limitations and their empirical remedies needs to be justified in order to reproducibly control fabrication of SRF cavities with desired characteristics. The high field Q-slope and mechanism behind its cure (120◦C mild vacuum bake) were investigated by comparison of the samples cut out of the cavities with high and low dissipation regions. Material evolution during mild field Q-slope nitrogen treatment was characterized using the coupon samples as well as samples cut out of nitrogen treated cavity. Evaluation of niobium near-surface state after some typical and novel cavity treatments was accomplished. Various TEM techniques, SEM, XPS, AES, XRD were used for the structural and chemical characterization of niobium near-surface. Combination of thermometry and structural temperature-dependent comparison of the cavity cutouts with different dissipation characteristics revealed precipitation of niobium hydrides to be the reason for medium and high field Q-slopes. Step-by-step effect of the nitrogen treatment processing on niobium surface was studied by analytical and structural characterization of the cavity cutout and niobium samples, which were subject to the treatment. Low concentration nitrogen doping is proposed to explain the benefit of nitrogen treatment. Chemical characterization of niobium samples before and after various surface processing (Electropolishing (EP), 800◦C bake, hydrofluoric acid (HF) rinsing) showed the differences that can help to reveal the microscopic effects behind these treatments as well as possible sources of surface contamination.
Ph.D. in Physics, December 2014
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Title: Chicago Politicians on Twitter
Creator: Hemphill, Libby, Shapiro, Matthew A., Otterbacher, Jahna
Date: 2012-03-12, 2012-03-12
Description: This paper uses data from 1,042 tweets posted by or mentioning Chicago Aldermen or Mayor Rahm Emanuel to examine how Chicago politicians use...
Show moreThis paper uses data from 1,042 tweets posted by or mentioning Chicago Aldermen or Mayor Rahm Emanuel to examine how Chicago politicians use social media. Twitter provides a public communication medium in which constituents and their representatives can have two-way conversations that others can witness and record, and we used qualitative and social network methods to examine conversations between Chicagoans and representatives in city government. We coded the contents of each tweet over the two-week time period (e.g., official business, fundraising) and created representations of the social networks created by the users’ following behaviors. These networks indicate who receives politicians’ tweets and help identify the audiences for political messaging in social media. Our analysis indicates that Chicago’s Aldermen and Mayor use Twitter for social conversations more often than political ones, and that only a small number of Aldermen dominate the resulting conversation networks.
Sponsorship: Social Network Research Group at IIT, IIT Graduate College
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Title: A HARDWARE-IN-THE-LOOP SOFTWARE-DEFINED NETWORKING TESTING AND EVALUATION FRAMEWORK
Creator: Yang, Qi
Date: 2017, 2017-05
Description: The transformation of innovative research ideas to production systems is highly dependent on the capability of performing realistic and...
Show moreThe transformation of innovative research ideas to production systems is highly dependent on the capability of performing realistic and reproducible network experiments. Simulation testbeds o↵er scalability, reproducibility but lack fidelity due to model abstraction and simplification, while physical testbeds o↵er high fidelity but lack reproducibility and often technically challenging and economically infeasible to perform large-scale experiments. In this work, we present a hybrid testbed consisting of container-based network emulation and physical devices to advocate high fidelity and reproducible networking experiments. In particular, the testbed integrates network emulators (Mininet) [5], a distributed control environment (ONOS) [1], physical switches (Pica8) and end-hosts (Raspberry Pi and commodity servers). The testbed (1) o↵ers functional fidelity through unmodified code execution on an emulated network, (2) supports large-scale network experiments using lightweight OS-level virtualization techniques and capable of running across distributed physical machines, (3) provides the topology flexibility, and (4) enhances the repeatability and reproducibility of network experiments. We validate the fidelity of the hybrid testbed through extensive experiments under di↵erent network conditions (e.g., varying topology and traffic pattern), and compare the results with the benchmark data collected on physical devices.
M.S. in Computer Science, May 2017
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Title: EXPLOITING NETWORK CODING IN DIFFERENT WIRELESS NETWORKS
Creator: Guo, Bin
Date: 2012-07-06, 2012-07
Description: Wireless communication networks have been incorporated into our daily life and provide convenience anytime and anywhere. However, the wireless...
Show moreWireless communication networks have been incorporated into our daily life and provide convenience anytime and anywhere. However, the wireless medium is unreliable and unpredictable. Current wireless networks suffer from low throughput, low reliability, etc. Network coding, an alternative approach, has attracted more interests and has emerged as an important technology in wireless networks. It can provide significant potential throughput improvements and a high degree of robustness. This dissertation is built on the theory of network coding. In this dissertation, different network coding protocols are designed in varied wireless networks. The first part of this dissertation proposes a novel coding-ware routing protocol in wireless mesh networks. In particular, a generalized coding condition is formally established to identify the coding opportunities. Based on general coding conditions analysis, a novel routing metric FORM (Free-ride Optimal Routing Metric) and the corresponding routing protocol are developed with the objective to exploit the coding opportunities and maximize the benefit of “free-ride” in order to reduce the total number of transmissions and consequently to increase the network throughput. The results show the proposed protocol achieves significant throughput gain than existing approaches. The second part of this dissertation exploits network coding in wireless cooperative networks. Firstly, a Decode-and-Forward Network Coded (DFNC) protocol is proposed for multi-user cooperative communication system. In particular, DFNC develops an efficient construction method for coding coefficients and a novel decoding algorithm that combines network coding and channel coding. DFNC exploits both temporal and spatial diversities through multiple channels by allowing all the users to generate redundant network-coded packets in a distributed manner and it helps fully explore the redundancy provided by network coding to realize error correction. Theoretical analysis and simulation results demonstrate that DFNC outperforms other transmission schemes in terms of Symbol Error Rate (SER) and achieves higher diversity order. Secondly, the idea of DFNC is extended and Modified-DFNC (M-DFNC) is introduced for a more practical scenario: not all the users will be able to dedicate their resources to provide assistance for others. The throughput analysis shows that M-DFNC outperforms the conventional cooperative protocol in the low-SNR regime and it implies that an adaptive cooperation system should be adopted to optimize the performance. The simulation results validate the theoretical analysis.
Ph.D. in Electrical Engineering, July 2012
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Title: Eco-Life (URBAN REDEVELOPMENT following CATASTROPHE in nanjing, china): Yingqiu Wu_Master project_poster
Creator: Wu, Yingqiu
Date: 2011-05-04, 2011-05
Description: My project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The...
Show moreMy project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The project proposes a new urban plan to rebuild the neighborhood and restore the community. A powerful explosion at an abandoned plastics factory in Qixia district of Nanjing city has left several people dead and dozens injured. Buildings and vehicles within 100m of the factory destroyed, 3000 citizen got the key of the street and buildings suffered varying degrees of damage in the area 8 miles in circumference. The blast was caused by a leak from a gas pipeline inside the factory, the blast happened after workers dismantling the plant damaged a propylene pipeline. The leaked gas was then ignited when a car engine was started at the scene. There were a community college and several kindergartens in this area, fortunately, it was summer break at that time, no students hurt reported. It is a unique opportunity to develop a plan in an urban context when the prior years of development have been wiped away. The purpose of the project is giving condos return to 3000 people who lost their houses in the explosion and planing mix-used buildings of the community for next 20 years. At present, many old nerghbourhoods in China are being replaced by new ones. In the most cases, the existing urban patternes are erased and a town is built with out any links to what had previouly existed there. My ptoposal is reusing most of the existing tree line streets, river and bridges. The key of this proposal is sustainability, first idea is using existing river to develop a nice wetland park and the second idea is farming gradens.
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Title: Control of grade transitions in distributed chemical reactor networks - An agent-based approach
Creator: Tetiker, M. Derya, Artel, Arsun, Teymour, Fouad, Cinar, Ali
Date: 2008-09-26
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Description: Supervision of distributed manufacturing processes producing different grades of a product requires intelligent reconfiguration strategies...
Show moreSupervision of distributed manufacturing processes producing different grades of a product requires intelligent reconfiguration strategies during grade transition phases to minimize off-spec production. Agent-based approaches are ideal for such problems and they provide flexible, robust, and emergent solutions during dynamically changing process conditions. Three different multi-layered multi-agent, frameworks are proposed for the supervision of grade transitions in autocatalytic reactor networks. The first framework is the centralized framework and it is useful for small-scale grade transitions where only a small region of the network needs to be reconfigured. Alternatively, the other two frameworks use a decentralized approach. The first decentralized framework implements genetic algorithms and the second one uses self-organizing heuristics and auctions for large-scale grade transitions. The case studies demonstrate that as the complexity of the reconfiguration problem increases, decentralized solutions perform more efficiently.
Endnote format citation for DOI:10.1016/j.compchemeng.2008.02.008
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Title: A COMPARATIVE-STUDY OF TOOLS FOR ASSESSING THE EFFECTS OF FORCED PERIODIC OPERATION OF CATALYTIC REACTORS
Creator: Ozgulsen, F., Rigopoulos, K. R., Cinar, A.
Date: 1992
Publisher: GORDON BREACH SCI PUBL LTD
Description: Two methods for assessing the effects of forced periodic catalytic reactor operation are presented. The vibrational control method is an...
Show moreTwo methods for assessing the effects of forced periodic catalytic reactor operation are presented. The vibrational control method is an analytical technique which evaluates the effects of high frequency forcing of system parameters by the method of averaging. The second technique is a numerical tool based on a shooting algorithm. These methods are capable of handling multiple input forcing and various shapes of forcing functions. Both methods are applied to isothermal, adiabatic and nonadiabatic operation of an internal recycle reactor in which the catalytic oxidation of ethylene takes place. The basic features of both techniques are discussed and the results obtained by using these methods are compared. Effects of single and multiple input parameter forcing are investigated. Experimental verification of the theoretical results is also performed for the isothermal case.
Endnote format citation
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Title: INVESTIGATION OF THE EFFICACY OF REACTIVE OXYGEN SPECIES GENERATED BY BOVINE AORTIC ENDOTHELIAL CELLS FOR INITIATING FREE-RADICAL POLYMERIZATION
Creator: Lu, Chenlin
Date: 2013, 2013-12
Description: Reactive oxygen species are reported to be generated by bovine aortic endothelial cells during ischemia followed by reperfusion. This...
Show moreReactive oxygen species are reported to be generated by bovine aortic endothelial cells during ischemia followed by reperfusion. This biological response, believed to be the cause of post-ischemic reperfusion injury, inspired us to investigate the possibility of coupling it with the initiation of free-radical polymerization to produce polymer hydrogels for cell encapsulation. In this work, the generation of reactive oxygen species during ischemia and reperfusion was examined by fluorescence detection and the feasibility of initiating free-radical polymerization by generated reactive oxygen species was investigated in two sets of experiments. The generation of reactive oxygen species by bovine aortic endothelial cells when subjected to anoxia followed by reoxygenation was investigated in both attached and suspended cells. Both intracellular and extracellular generations of ROS appeared to occur in the experiments of attached cells. Cell viability experiments demonstrated that the generation of ROS was sufficient to cause cell damage and death. The feasibility of initiating free-radical polymerization by reactive oxygen species generated by bovine aortic endothelial cells subjected to anoxia followed by reoxygenation was investigated in two sets of experiments. One set involved the linear polymerization of NVP which allowed us to quantify the extent of polymerization and characterization of the weight conversion of PVP polymer. The other set involved the formation of PEGDA hydrogels which were characterized by imaging and staining methods. To our knowledge this is the first evidence of cell induced polymerization initiated by reactive oxygen species and gelation which can be used for a variety of biomedical applications.
M.S. in Chemical and Biological Engineering, December 2013
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Title: Water power development at Iowa Falls, Iowa
Creator: Dowdell, Charles O.
Date: 2009, 1907
Publisher: Armour Institute of Technology
Description: http://www.archive.org/details/waterpowerdevelo00dowd
Thesis (B.S.)--Armour Institute of Technology; Bibliography: leaf 12

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