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Title: Contract Rollover and Volatility
Creator: Chen, Yue
Date: 2022
Description: In futures markets, approaching the expiration days, most market participants close out existing positions of front month contract and open...
Show moreIn futures markets, approaching the expiration days, most market participants close out existing positions of front month contract and open new positions of next month contract. The object of this dissertation is to evaluate the impact of contract rollover activities on unconditional volatility and conditional volatility modeling. First, two contract rollover measures, volume ratio and open interest ratio of front contract over next contract are created. Second, this study investigates the impact of contract rollover measures on both unconditional volatility estimation models and conditional volatility estimation models. Third, it examines the roles of contract rollover activities in unconditional volatility prediction models. Last, to further explore the relationship between contract rollover measures and unconditional volatilities, the vector autoregressive model is conducted to test granger causality. The findings show that the volume ratio and open interest ratio have significant impact on unconditional volatilities and conditional volatility in soybean, wheat, gold, copper, crude oil, and natural gas futures markets, except on conditional volatility in silver futures market. Alternative models that incorporate contract rollover measures outperform benchmark models that do not incorporate contract rollover measures in both estimation models and prediction models. Moreover, the findings provide the strong evidence that there is significant bidirectional granger causality among volume ratio, open interest ratio and unconditional volatilities in all investigated futures markets. The empirical results confirm the important role of contract rollover on volatility behavior and are beneficial to futures exchanges to set and monitor margins precisely for their customer’s trading accounts in commodity futures markets.
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Title: INFORMATION EFFICIENCY AND THE EFFECT OF HIGH FREQUENCY TRADING IN THE U.S. FUTURES MARKETS
Creator: CHA, SEUNG YOUN
Date: 2021
Description: The paper gives an empirical analysis with the U.S. futures market data on how High Frequency Trading, HFT can improve the information...
Show moreThe paper gives an empirical analysis with the U.S. futures market data on how High Frequency Trading, HFT can improve the information efficiency of asset prices. Various analyses were conducted to determine the degree of efficiency of information in futures high-frequency trading. The paper tries to explain the effect of high-frequency trading on the efficiency of the market in various ways and tries to propose stepping stones for developing a new market analysis measure.The research builds a coherent framework for analyzing both linear and non-linear market efficiency and applies it to a variety of futures contracts using high- frequency data. The major finding of this paper is that market efficiency levels vary widely over time depending on market characteristics. The paper also finds that HFT activities are higher when the market is inefficient. The paper analyzes the relationship between high frequency trading activities and market efficiency and discovers the mechanism. The story that HFT activity responds to market efficiency needs is especially strong in the E-mini, S&P500 futures contract.
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Title: Hedge Fund Replication With Deep Neural Networks And Generative Adversarial Networks
Creator: Chatterji, Devin Mathew
Date: 2022
Description: Hedge fund replication is a means for allowing investors to achieve hedge fund-like returns, which are usually only available to institutions....
Show moreHedge fund replication is a means for allowing investors to achieve hedge fund-like returns, which are usually only available to institutions. Hedge funds in total have over $3 trillion in assets under management (AUM). More traditional money managers would like to offer hedge fund-like returns to retail investors by replicating their performance. There are two primary challenges with existing hedge fund replication methods, difficulty capturing the nonlinear and dynamic exposures of hedge funds with respect to the factors, and difficulty in identifying the right factors that reflect those exposures. It has been shown in previous research that deep neural networks (DNN) outperform other linear and machine learning models when working with financial applications. This is due to the ability of DNNs to model complex relationships, such as non-linearities and interaction effects, between input features without over-fitting. My research investigates DNNs and generative adversarial networks (GAN) in order to address the challenges of factor-based hedge fund replication. Neither of these methods have been applied to the hedge fund replication problem. My research contributes to the literature by showing that the use of these DNNs and GANs addresses the existing challenges in hedge fund replication and improves on results in the literature.
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Title: A BIM-BASED LIFE CYCLE ASSESSMENT TOOL OF EMBODIED ENERGY AND ENVIRONMENTAL IMPACTS OF REINFORCED CONCRETE TALL BUILDINGS
Creator: Ma, Lijian
Date: 2022
Description: Today 55 percent of population in the world lives in urban areas which is expected to increase to 68 percent by the year 2050. In the cities,...
Show moreToday 55 percent of population in the world lives in urban areas which is expected to increase to 68 percent by the year 2050. In the cities, high-rise buildings as symbols of the modern cityscape are dominating the skylines, but the data to demonstrate their embodied energy and environmental impacts are scarce, compared to low- or mid-rise buildings. Reducing the embodied energy and environmental impacts of buildings is critical as about 42 percent of primary energy use and 39 percent of the global greenhouse gas (GHG) emissions come from the building sector. However, it is an overlooked area in embodied energy and environmental impacts of tall buildings. This doctoral research aims to investigate the effects of tall buildings on embodied energy and environmental impacts by using process-based life cycle assessment (LCA) methodology within Building Information Modelling (BIM) environment, which provides construction industry platform to incorporate sustainability information in architectural design. This doctoral research is carried out through a literature review on embodied energy of high-rise buildings. Current LCA methods of buildings are also discussed in the literature review. It then develops a framework for BIM-based assessment of the embodied energy and environmental impacts of tall buildings. To achieve that, a case study of tall reinforced concrete building is applied, by using ISO 14040 and 14044 guidelines with available database, Revit and Tally application in Revit. The author concentrates on embodied energy and environmental impacts of reinforced concrete tall buildings. Finally, the association between design and construction variables with embodied energy and environmental impacts is explored. This research will lead to significant contributions. A comprehensive study on embodied energy and environmental impacts of high-rise building will address a major gap in LCA literature. Researchers and environmental consultants can use the results of this research to create design tools to evaluate environmental impacts of high-rise buildings. Also, architects can use the results of this research to develop insight into the environmental performance of tall buildings in early design stage. Architects and engineers can also use the results to optimize tall building design for low embodied energy and environmental impacts. Finally, the results of this research will enable architects, engineers, planners, and policymakers develop more sustainable built environments.
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Title: Active Load Control in a Synchronized and Democratized (SYNDEM) Smart Grid
Creator: Lv, Zijun
Date: 2021
Description: Smart grid is envisioned to take advantage of modern information and communication technologies in achieving a more intelligent grid in order...
Show moreSmart grid is envisioned to take advantage of modern information and communication technologies in achieving a more intelligent grid in order to facilitate: Integration of renewable resources; Integration of all types of energy storage; Two-way communication between the consumer and utility so that end users can actively participate. The Synchronized and Democratized (SYNDEM) smart grid is regarded as the next generation smart grid. The objective of the SYNDEM smart grid is for all active players in a grid, large or small, conventional or renewable, supplying or consuming, to be able to equally and laterally regulate the grid in a synchronous manner to enhance the stability, reliability, and resiliency of future power systems. In a SYNDEM smart grid, power electronic converters are controlled to behave as conventional synchronous machines. Such converters are called virtual synchronous machines (VSMs).Following the SYNDEM structure, this thesis mainly focuses on developing the VSM technology for the automatic grid regulation at the demand side. The major aim and objective is to achieve active or intelligent loads that can flexibly and automatically take part in grid regulation. Moreover, the active load is expected to have similar grid regulation behavior as other active players in the grid, for e.g., renewable generations. To achieve this, a droop-controlled rectifier is proposed that acts as a general interface for a load to grid. The rectifier is controlled as a VSM so that a load equipped with such a rectifier can take part in grid regulation continuously like a traditional synchronous machine. Such a rectifier has a built-in storage port, in addition to the normal AC and DC ports. The flexibility required by the AC port to support the grid is provided by the storage port. The DC-bus voltage of the storage port is able to fluctuate with in a wide range to exchange energy with the grid.In order to further take use of the energy in the storage port (DC-bus capacitor) of a rectifier more reasonably and increase the support time to grid, an adaptive droop mechanism is proposed. Under such a droop mechanism, the rectifier can automatically change the power consumed according to the grid voltage variations as well as its potential to provide grid support. To achieve this, a flexibility coefficient is introduced to indicate the power flexibility level of the DC-bus capacitor. Then this flexibility coefficient is embedded into the universal droop controller (UDC) to make it adaptive. Hence, the adaptive droop controller has a changing droop coefficient corresponding to the power flexibility of a rectifier, so it can take advantage of the energy stored in its DC-bus capacitor wisely to support the grid. This droop controller can also be applied into connection between two SYNDEM smart grids. To achieve this, a grid bridge (GB) that enables autonomous and equal regulation between two SYNDEM grids is proposed. The real power transferred through a GB has linear relationship with the voltage deviation between the two micro-grids connected. The micro-grid with a higher voltage will automatically provide power to the lower one. Moreover, the power direction of a GB is bidirectional and determined by the grid voltage difference, this makes the two micro-grids equal to each other. The GB is physically a back-to-back converter. In order to achieve autonomous and equal regulation, both sides of the back-to-back converter are controlled under droop controller with the same droop coefficients. The VSM control technology is also developed to control Modular multilevel converters (MMCs) for high voltage applications. Like active loads introduced above, the MMCs can take part in the grid regulation according to the droop mechanism designed. In order to eliminate the circulating current that exists in MMCs, proportional-resonant (PR) controllers are adopted to inject second-order harmonics to the MMCs to suppress the second order circulating current. The dynamics, implementation and operation of the VSM-like MMC are introduced and analyzed. Particularly, how the VSM control algorithm works with the circulating current control in MMCs is presented. An IIT SYNDEM Smart Grid Testbed is built in an aim of achieving a minimize realization of the SYNDEM system. Extensive experiments are done on the system to show the operational scenarios when the proposed active loads are integrated in the system. There are in total eight nodes in the IIT SYNDEM testbed, which contains two utility grids, one AC load, one DC load, two solar farms and two wind farms. All the nodes are connected to a local grid through VSMs, so that they can take part in the local grid regulations in similar ways. The IIT SYNDEM Smart Grid Testbed is described in details and experimental results are provided to show the dynamic and steady performance of the IIT SYNDEM smart grid.
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Title: Modeling, Analysis and Computation of Tumor Growth
Creator: Lu, Min-Jhe
Date: 2022
Description: In this thesis we investigate the modeling, analysis and computation of tumor growth.The sharp interface model we considered is to understand...
Show moreIn this thesis we investigate the modeling, analysis and computation of tumor growth.The sharp interface model we considered is to understand how the two key factors of (1) the mechanical interaction between the tumor cells and their surroundings, and (2) the biochemical reactions in the microenvironment of tumor cells can influence the dynamics of tumor growth. From this general model we give its energy formulation and solve it numerically using the boundary integral methods and the small-scale decomposition under three different scenarios.The first application is the two-phase Stokes model, in which tumor cells and the extracellular matrix are both assumed to behave like viscous fluids. We compared the effect of membrane elasticity on the tumor interface and the curvature-weakening one and found the latter would promote the development of branching patterns.The second application is the two-phase nutrient model under complex far-field geometries, which represents the heterogeneous vascular distribution. Our nonlinear simulations reveal that vascular heterogeneity plays an important role in the development of morphological instabilities that range from fingering and chain-like morphologies to compact,plate-like shapes in two-dimensions.The third application is for the effect of angiogenesis, chemotaxis and the control of necrosis. Our nonlinear simulations reveal the stabilizing effects of angiogenesis and the destabilizing ones of chemotaxisand necrosis in the development of tumor morphological instabilities if the necrotic core is fixed. We also perform the bifurcation analysis for this model.In the end, as a future work, we propose new models through Energetic Variational Approach (EnVarA) to shed light on the modeling issues.
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Title: GLOBAL ESTIMATION AND ANALYSIS OF IONOSPHERIC DRIVERS WITH A DATA ASSIMILATION ALGORITHM
Creator: López Rubio, Aurora
Date: 2022
Description: This dissertation studies a data assimilation algorithm that estimates the drivers of the ionosphere-thermosphere (IT) region of the Earth....
Show moreThis dissertation studies a data assimilation algorithm that estimates the drivers of the ionosphere-thermosphere (IT) region of the Earth. The algorithm, EMPIRE (Estimating Model Parameters from Ionospheric Reverse Engineering) can estimate 2 main drivers of the ionospheric behavior: neutral winds and electric potential by ingesting mainly ionospheric densities obtained through Global Satellite System (GNSS) measurements. Additionally, the algorithm can ingest FPI (Fabry-Perot interferometer) neutral wind measurements. The contributions include 1) Vector spherical harmonic basis function for neutral wind estimation, 2) Quantification of the representation error of the estimations of the algorithm EMPIRE, 3) Analysis of Nighttime Ionospheric Localized density Enhancement (NILE) events and 4) Ingestion of global ICON (Ionospheric Connection Explorer) neutral winds measurements. The IT region in the atmosphere is characterized by having a large concentration of free ions and electrons, electromagnetic radiation and Earth's magnetic field. The behavior of the region is dominated by the solar activity, that ionizes the free electrons of the region, forming ionospheric plasma and determining its density. Unusual solar activity or any atmospheric disturbance affects the distribution of the ionospheric plasma and the behavior of the IT region. The redistribution of the ionospheric density impacts technology widely used such as telecommunication or satellite navigation, so it is increasingly important to study the IT system response. The IT behavior can be characterized by what drives its changes. Two drivers that play a key role, the ones we focus on this dissertation, are electric potential, that directly affects the charged ions in the system, and neutral winds, that refers to the velocity of the neutral particles that form the thermosphere. To quantify these drivers, measurements and climate models are available. Measurements are limited as the IT region is vast and covers the entire globe. Climate models can provide information in all the region, but they are usually not as reliable during the unusual solar activity conditions or disturbances. In this dissertation we use a data assimilation algorithm, EMPIRE, that combines both sources of data, measurements and models, to estimate the IT drivers, neutral winds and electric potential. EMPIRE ingests measurements of the plasma density rate and models the physics of the region with the ion continuity equation. The drivers are represented with basis functions and their coefficients are estimated by fitting the expansions with a Kalman filter. In previous work and use of the algorithm, the neutral winds were expanded using power series basis function for each of the components of the vector. The first contribution of the dissertation is to use a vector spherical harmonic expansion to describe the winds, allowing a continuous expansion around the globe and self-consistent components of the vector. Before, EMPIRE estimated the correction of the drivers with respect climate model values. In this work, EMPIRE is also modified to directly estimate the drivers. Then, a study of the representation error, which is the discrepancy between the true physics and the discrete model that represents the physics of EMPIRE and its quantification is done. Next, EMPIRE is used to analyze two NILE events, using the global estimation of both winds, from the first contribution, and the electric potential, derived in previous work. Finally, global estimation of winds allows us to implement the ingestion of ICON global winds in EMPIRE, in addition to the plasma density rate measurements.
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Title: Machine learning applications to video surveillance camera placement and medical imaging quality assessment
Creator: Lorente Gomez, Iris
Date: 2022
Description: In this work, we used machine learning techniques and data analysis to approach two applications. The first one, in collaboration with the...
Show moreIn this work, we used machine learning techniques and data analysis to approach two applications. The first one, in collaboration with the Chicago Police Department (CPD), involves analyzing and quantifying the effect that the installation of cameras had on crime, and developing a predictive model with the goal of optimizing video surveillance camera location in the streets. While video surveillance has become increasingly prevalent in policing, its intended effect on crime prevention has not been comprehensively studied in major cities in the US. In this study, we retrospectively analyzed the crime activities in the vicinity of 2,021 surveillance cameras installed between 2005 and 2016 in the city of Chicago. Using Difference-in-Differences (DiD) analysis, we examined the daily crime counts that occurred within the fields-of-view of these cameras over a 12-month period, both before and after the cameras were installed. We also investigated their potential effect on crime displacement and diffusion by examining the crime activities in a buffer zone (up to 900 ft) extended from the cameras. The results show that, collectively, there was an 18.6% reduction in crime counts within the direct viewsheds of all of the study cameras (excluding District 01 where the Loop -Chicago's business center- is located). In addition, we adapted the methodology to quantify the effect of individual cameras. The quantified effect on crime is the prediction target of our 2-stage machine learning algorithm that aims to estimate the effect that installing a videocamera in a given location will have on crime. In the first stage, we trained a classifier to predict if installing a videocamera in a given location will result in a statistically significant decrease in crime. If so, the data goes through a regression model trained to estimate the quantified effect on crime that the camera installation will have. Finally, we propose two strategies, using our 2-stage predictive model, to find the optimal locations for camera installations given a budget. Our proposed strategies result in a larger decrease in crime than a baseline strategy based on choosing the locations with higher crime density.The second application that forms this thesis belongs to the field of model observers for medical imaging quality assessment. With the advance of medical imaging devices and technology, there is a need to evaluate and validate new image reconstruction algorithms. Image quality is traditionally evaluated by using numerical figures of merit that indicate similarity between the reconstruction and the original. In medical imaging, a good reconstruction strategy should be one that helps the radiologist perform a correct diagnosis. For this reason, medical imaging reconstruction strategies should be evaluated on a task-based approach by measuring human diagnosis accuracy. Model observers (MO) are algorithms capable of acting as human surrogates to evaluate reconstruction strategies, reducing significantly the time and cost of organizing sessions with expert radiologists. In this work, we develop a methodology to estimate a deep learning based model observer for a defect localization task using a synthetic dataset that simulates images with statistical properties similar to trans-axial sections of X-ray computed tomography (CT). In addition, we explore how the models access diagnostic information from the images using psychophysical methods that have been previously employed to analyze how the humans extract the information. Our models are independently trained for five different humans and are able to generalize to images with noise statistic backgrounds that were not seen during the model training stage. In addition, our results indicate that the diagnostic information extracted by the models matches the one extracted by the humans.
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Title: EXAMINING PERFORMANCE DEGRADATION OF LI-ION BATTERIES WITH SILICON-BASED ANODE AND POSSIBLE SOLUTIONS TO IMPROVE THE SILICON ANODE BEHAVIOR
Creator: Luo, Mei
Date: 2022
Description: Si has been investigated as a promising alternative to conventional graphite because of its high specific capacity and wide operating voltage;...
Show moreSi has been investigated as a promising alternative to conventional graphite because of its high specific capacity and wide operating voltage; however, technical challenges related to volume change in the silicon anode have hampered their practical application. In this work, the effects of silicon volume change on electrochemical performance has been studied in NMC532/Si full cells. First, different area specific capacity ratios of the negative to positive electrode (N:P ratio) were investigated using three-electrode cells. With individual electrode potentials monitored by a reference electrode, different depths of lithiation/delithiation at the anode and cathode were found to play an important role on cell performance; the cell with higher N:P ratio displays superior electrochemical performance due to its smaller silicon volume change. Further, calendar-life aging and cycle-life aging of NMC532/Si cells were compared with their electrode potentials monitored using a reference electrode. The observation of larger capacity decay and impedance growth of cycle-life aging cells illustrates the important effect of silicon volume change; significant capacity decay of calendar-life aged cell was observed as well, revealing an essential role of chemical effect of ongoing side reactions at Si anode. Specially-designed silicon with different protocols and electrolyte additives were investigated to address the intrinsic challenges of Si anodes for lithium-ion batteries.
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Title: ARCHITECTURE FOR COLLABORATIVE CREATIVITY - SPACE WE-Q: SPACE INTELLIGENCE EMPOWERING CREATIVE WE CULTURE IN LEARNING-DRIVEN ENVIRONMENTS
Creator: Mor-Avi, Anat
Date: 2020
Description: Changes in societal culture, along with research on how we learn, challenge current architectural solutions. Education’s shifting paradigms...
Show moreChanges in societal culture, along with research on how we learn, challenge current architectural solutions. Education’s shifting paradigms align with these changes and move teaching strategies from teacher-centered to learner-centered, and from formal and passive, to informal and active modes. Another shift emphasizes collaboration and participatory creativity, which evolve the idea of the “collective,” or “We” versus “I” scenarios. In addition, studies show that creativity flourishes in specific contradictory performances. Supporting these reported changes, new knowledge, and paradigm shifts, this research studied how an active, adaptive architectural design approach might emerge into the learning and creative processes. Evidence indicates that “design and space do matter,” particularly in learning- and working-driven domains. Empirical research has been weak in addressing this understanding relative to architectural solutions, affordances, behaviors, and emotions, promoting collaborative creativity. This research aimed to investigate patterns of architectural affordances believing to impact and empower collaborative cultures and behaviors in learning environments (“WE CULTURE”), specifically motions and emotions. A Mixed-method research design was conducted, using two techniques: (a) a content analysis of awarded learning and working environments, and (b) a post-occupancy evaluation using ethnographic techniques to study the Kaplan Innovation Institute at the Illinois Institute of Technology in Chicago, Illinois, USA. In an effort to provide an applied design study, a visual pattern language related to cultures of learning, environment behavior, and emotions was developed. The pattern language is the platform for designing intelligent spaces, SPACE WE-Q, promoting collaborative behaviors, and creativity through adaptive and behavior-based systems of active affordances. SPACE WE-Q offers a planned adaptive system for unplanned creative processes that emerges into learning and suggesting a new relationship between architecture and education, between architects and users, and between users and space.
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Title: Promoting Healthy Lifestyle Behaviors for African Americans with Serious Mental Illness and Weight Concerns
Creator: Nieweglowski, Katherine
Date: 2022
Description: People with serious mental illness face greater rates of chronic illness and obesity compared to those without mental illness. These rates are...
Show morePeople with serious mental illness face greater rates of chronic illness and obesity compared to those without mental illness. These rates are disproportionately higher for those who are part of racially minoritized groups. For example, African Americans are more likely to be obese compared to their white counterparts. This study sought to test a diet and exercise program—developed through community-based participatory research—called “Behaviors for Healthy Lifestyles” (BHL) for African Americans with serious mental illness and weight concerns. The impact of this program, also combined with peer health navigation (PHN), was tested on various physical and mental health outcomes. Participants were randomly assigned to either integrated-care treatment as usual (IC-TAU), BHL, or BHL+PHN. Data was collected at baseline, 4-month, 8-month, and 12-month follow up for outcomes measuring general health, bodily pain, physical functioning, emotional well-being, depression, recovery, quality of life, weight efficacy, and emotional eating. Monthly data collection was also conducted on frequency of healthy lifestyle behaviors related to diet and physical activity. Findings from group by trial analyses of variance on these outcomes did not show any significant impact. Implications for testing diet and exercise interventions combined with PHN for this population are discussed along with future research considerations related to increasing attendance and participation for greater health improvements.
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Title: Development and evaluation of high resolution MRI templates and labels of the MIITRA atlas
Creator: Niaz, Mohammad Rakeen
Date: 2022
Description: A digital human brain atlas consisting of MRI-based multi-modal templates and semantic labels delineating brain regions are commonly used as...
Show moreA digital human brain atlas consisting of MRI-based multi-modal templates and semantic labels delineating brain regions are commonly used as references for spatial normalization in a wide range of neuroimaging studies. Magnetic resonance imaging (MRI) studies of the aging brain is of significant interest in recent times to explore the role of brain characteristics associated with cognitive functions. The introduction of advanced image reconstruction techniques, and the recent trend in MRI acquisitions at submillimeter in-plane resolution have resulted in an easier availability of MRI data on older adults at high spatial resolution. An atlas with a comprehensive set of high-resolution templates representative of the older adult brain and detailed labels accurately mapping brain regions can increase the sensitivity and specificity of such neuroimaging studies. Additionally, most neuroimaging studies can benefit from a high-resolution atlas with templates where fine brain structures are resolved and, where the transition between different tissue can be more accurately defined. However, such an atlas is not publicly available for older adults. Hence the goal of this thesis is to develop a comprehensive, high-resolution digital human brain atlas for older adults termed as Multi-channel Illinois Institute of Technology and Rush University Aging (MIITRA) atlas.This dissertation aims a) to develop a new technique based on the principles of super-resolution for the construction of high-resolution structural and diffusion tensor templates, and evaluate the templates for use in studies on older adults, b) to construct and evaluate high-resolution structural and diffusion tensor templates constructed using the method developed in (a) for the MIITRA atlas using MRI data collected on 400 nondemented older adults, c) to investigate and develop a technique for the construction of high-resolution labels and evaluate the performance of gray matter labels constructed using this technique in segmenting the gray matter of older adults, and d) to develop and evaluate a comprehensive set of high-resolution labels using the technique developed in (c) for the MIITRA atlas using data on 400 non-demented older adults. Based on the aforementioned points, the thesis is structured as follows: Firstly, this thesis presents a novel approach for the construction of a high-resolution T1-weighted structural template based on the principles of super resolution. This method introduced a forward mapping technique to minimize signal interpolation, and a weighted averaging method to account for residual misregistration. The new template was shown to resolve finer brain structures compared to a lower resolution template constructed using the same data. It was demonstrated through systematic comparison of this new template to several other standardized templates of different resolutions that a) it exhibited high image sharpness, b) was free of image artifacts, c) allowed for high spatial normalization accuracy and detection of smaller inter-group morphometric differences compared to other standardized templates, d) was highly representative of the older adult brain. This novel approach was further modified for the construction of a high spatial resolution diffusion tensor imaging template. The new DTI template is the first high spatial resolution population-based DTI template of the older adult brain and exhibits high image quality, high sharpness, is free of artifacts, resolves fine white matter structures, and provides higher spatial normalization accuracy of older adult DTI data compared to other available DTI templates. Secondly, the aforementioned techniques were utilized in the development of high resolution T1-weighted and DTI templates, and tissue probability maps for the MIITRA atlas using high quality MRI images on 400 diverse, community cohort of non-demented older adults. Thirdly, a novel approach for generating high resolution gray matter labels is presented that involves a) utilization of the super resolution technique to ensure sharp delineation of structures, and b) a multi atlas based correction technique to reduce errors due to misregistration. High-resolution gray matter labels were constructed using the super resolution technique. When used for regional segmentation of the gray matter of older adults, the new gray matter labels of the showed high overlap, high geometric correlation, and low dissimilarity with the manually edited reference labels, demonstrating that there is a high agreement between the new labels and the manually edited Freesurfer labels. Finally, this thesis presents the development of a comprehensive array of gyral-based, cytoarchitecture-based, and functional connectivity-based gray matter labels in MIITRA space utilizing the aforementioned techniques. These labels include gyral-based, cytoarchitecture-based, and functional connectivity-based labels which will enhance the functionality of the MIITRA atlas. The new labels will also enhance the interoperability of MIITRA with the source atlases.
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Title: The Detection of Emerging Pathogenic Arcobacter Species In Poultry and Poultry By-Products
Creator: Nguyen, Paul
Date: 2022
Description: Arcobacter species are emerging foodborne pathogens that are associated with human gastrointestinal illness. Typical symptoms of Arcobacter...
Show moreArcobacter species are emerging foodborne pathogens that are associated with human gastrointestinal illness. Typical symptoms of Arcobacter infection that have been reported include diarrhea, abdominal cramps, nausea, vomiting, and in severe cases, bacteremia. Consumption of contaminated food and water is the most common transmission source that leads to human infection. When consumed, pathogenic Arcobacter spp. pass through the stomach and establishes themselves in the host intestinal tract, where they cause gastroenteritis. Currently, there is no standard isolation method to detect pathogenic Arcobacter spp. from food and environment sample matrices. The research detailed in this thesis describes the development of the Nguyen-Restaino-Juárez Arcobacter detection system (NRJ) comprised of a selective enrichment broth and a chromogenic agar plate used to isolate three pathogenic species: Arcobacter butzleri, Arcobacter cryaerophilus, and Arcobacter skirrowii. Results revealed that NRJ yielded 97.8% inclusivity and 100.0% exclusivity when evaluating against select bacterial strains found in foods. Our research group internally validated the novel chromogenic detection system by comparing its efficacy against the modified Houf reference method (HB). Method-performance evaluations determined the NRJ method was significantly more sensitive and specific than modified HB when isolating the three Arcobacter species from ground chicken samples. Furthermore, 16S amplicon sequencing data identified that greater than 97% of bacterial isolates recovered using the NRJ detection system were Arcobacter species. This thesis presents the development and validation of a new gold standard method for isolating these emerging pathogens in food, clinical and environmental sampling.
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Title: Non-Hermitian Phononics
Creator: Mokhtari, Amir Ashkan
Date: 2021
Description: Non-Hermitian and open systems are those that interact with their environment by the ﬂows of energy, particles, and information. These systems...
Show moreNon-Hermitian and open systems are those that interact with their environment by the ﬂows of energy, particles, and information. These systems show rich physical behaviors such as unidirectional wave reflection, enhanced transmission, and enhanced sensitivity to external perturbations comparing to a Hermitian system. To study non-Hermitian and open systems, we first present key concepts and required mathematical tools such as the theory of linear operators, linear algebra, biorthogonality, and exceptional points. We first consider the operator properties of various phononic eigenvalue problems. The aim is to answer some fundamental questions about the eigenvalues and eigenvectors of phononic operators. These include questions about the potential real and complex nature of the eigenvalues, whether the eigenvectors form a complete basis, what are the right orthogonality relationships, and how to create a complete basis when none may exist at the outset. In doing so we present a unified understanding of the properties of the phononic eigenvalues and eigenvectors which would emerge from any numerical method employed to compute such quantities. Next, we apply the mentioned theories on the phononic operators to the problem of scattering of in-plane waves at an interface between a homogeneous medium and a layered composite. This problem is an example of a non self-adjoint operator with biorthogonal eigenvectors and a complex spectrum. Since this problem is non self-adjoint, the degeneracies in the spectrum generally represent a coalescing of both the eigenvalues and eigenvectors (exceptional points). These degeneracies appear in both the complex and real domains of the wavevector. After calculating the eigenvalues and eigenvectors, we then calculate the scattered fields through a novel application of the Betti-Rayleigh reciprocity theorem. Several numerical examples showing rich scattering phenomena are presented afterward. We also prove that energy flux conservation is a restatement of the biorthogonality relationship of the non self-adjoint operators. Finally, we discuss open elastodynamics as a subset of non-Hermitian systems. A basic concept in open systems is effective Hamiltonian. It is a Hamiltonian that acts in the space of reduced set of degrees of freedom in a system and describes only a part of the eigenvalue spectrum of the total Hamiltonian. We present the Feshbach projection operator formalism -- traditionally used for calculating effective Hamiltonians of subsystems in quantum systems -- in the context of mechanical wave propagation problems. The formalism allows for the direct formal representation of effective Hamiltonians of finite systems which are interacting with their environment. This results in a smaller set of equations which isolate the dynamics of the system from the rest of the larger problem that is usually infinite size. We then present the procedure to calculate the Green's function of effective Hamiltonian. Finally we solve the scattering problem in 1D discrete systems using the Green's function method.
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Title: TWO ESSAYS IN SUSTAINABILITY AND ASSET RETURN PREDICTABILITY
Creator: Nguyen, Lanh Vu Thuc
Date: 2021
Description: Our paper consists of two chapters in Financial Modeling for Sustainability and Asset Return Predictability. Recent developments in data...
Show moreOur paper consists of two chapters in Financial Modeling for Sustainability and Asset Return Predictability. Recent developments in data scraping and analytical methods have enhanced the possibility to construct the data and modeling required to examine the topics in each chapter. Chapter 1 proposes a simple yet strategic model involving a personal financial system to achieve a sustainable and prosperous future. The proposed model emphasizes the optimization of carbon footprints of one person at a time through the decentralization of the electricity use. While describing steps to develop a decentralized system considering electricity as a credit product, the model also underlines the importance of geographic economic dimensions and energy market prices due to their anticipated impact on the effectiveness of designing strategies for optimizing individuals’ energy use habits. Geographical conditions as well as market electricity prices can be used to signal individual energy use scores over time, therefore could also be instrumental in customizing energy use habits as the users realize variations in their energy use scores resulting from hourly electricity price changes at their locations. In other words, not only the changes in the individual’s behavior, but also the changes in the geographical conditions and community of users will affect the improvement of energy use behaviors of an individual over time using our model. We believe that the proposed model can be efficiently adopted to take on challenges threatening the future sustainability. While describing the basic characteristics of the model, we also open the possibility for future studies its capabilities to reduce carbon footprints from other societal choices, for example, using water, managing waste, or designing sustainable transportation systems. In Chapter 2, we examine asset return predictability, which is an important topic in finance with rich literature. Much of the current literature considers dividend yield as the main predictor for expected returns, and the main discussion centers around confirming or rejecting the predictive power of dividend yield with mixed evidence. However, dividend payments have been consistently declining and public firms have been increasingly using stock repurchase as the alternative to return values to shareholders. We aim to contribute to the literature by investigating a panel data of total equity payout, which takes into account not only dividend payout but also other forms of payment such as stock repurchase, as the main predictor for expected returns. In the asset return predictability literature, existing studies gather stock repurchase data from financial statements. In this paper, we manually construct our database of returns and payouts of public companies from various sources to create precise firm-level total equity payout dataset without relying on approximations from annual financial statements. This study adds to understanding of total equity payout and stock returns by analyzing a finer granularity than an annum and cross section of stock returns.
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Title: DEEP LEARNING IMAGE-DENOISING FOR IMPROVING DIAGNOSTIC ACCURACY IN CARDIAC SPECT
Creator: Liu, Junchi
Date: 2022
Description: Myocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) is a noninvasive imaging modality widely utilized...
Show moreMyocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) is a noninvasive imaging modality widely utilized for diagnosis of coronary artery diseases (CAD) in nuclear medicine. Because of the concern of potential radiation risks, the imaging dose administered to patients is limited in SPECT-MPI. Due to the low count statistics in acquired data, SPECT images can suffer from high levels of noise. In this study, we investigate the potential benefit of applying deep learning (DL) techniques for denoising in SPECT-MPI studies. Owing to the lack of ground truth in clinical studies, we adopt a noise-to-noise (N2N) training approach for denoising in full-dose studies. Afterwards, we investigate the benefit of applying N2N DL on reduced-dose studies to improve the detection accuracy of perfusion defects. To address the great variability in noise level among different subjects, we propose a scheme to account for the inter-subject variabilities in training a DL denoising network to improve its generalizability. In addition, we propose a dose-blind training approach for denoising at multiple reduced-dose levels. Moreover, we investigate several training schemes to address the issue that defect and non-defect image regions are highly unbalanced in a data set, where the overwhelming majority by non-defect regions tends to have a more pronounced contribution to the conventional loss function. We investigate whether these training schemes can effectively improve preservation of perfusion defects and yield better defect detection accuracy. In the experiments we demonstrated the proposed approaches with a set of 895 clinical acquisitions. The results show promising performance in denoising and improving the detectability of perfusion-defects with the proposed approaches.
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Title: Evolution and adaptations to host plants in the beetle genus Diabrotica
Creator: Lata, Dimpal
Date: 2022
Description: Corn rootworms (Diabrotica spp.) are among the most destructive pests impacting agriculture in the U.S and are an emerging model for insect...
Show moreCorn rootworms (Diabrotica spp.) are among the most destructive pests impacting agriculture in the U.S and are an emerging model for insect-plant interactions. We have a limited understanding of the genome-scale level difference between specialist and generalist corn rootworm species and their interaction with their host plants. Genome sizesof several species in the genus Diabrotica and an outgroup were estimated using flow cytometry. Results indicated that there has been a recent expansion in genome size in the common ancestor of the virgifera group leading to Diabrotica barberi, Diabrotica virgifera virgifera, and Diabrotica virgifera zeae. Comparative genomic studies between the fucata and virgifera groups of Diabrotica revealed that repeat elements, mostly miniature inverted-transposable elements (MITEs) and gypsy-like long terminal repeat (LTR) retroelements, contributed to genome size expansion. The initial transcriptional profile in western corn rootworm neonates when fed on different potential host plants demonstrated a strong association between western corn rootworm and maize, which was very distinct from other possible hosts and non-host plants. The results also showed presence of several larval development related transcripts unique to host plants and the presence of several muscle development and stress response related transcripts unique to non-host plants. The effect of the maize defensive metabolite DIMBOA on corn rootworms was studied using a novel plant-free system. The survival of both southern and western corn rootworms was not affected at a low concentration of DIMBOA. However, the concentration above the physiological dose found in plants affected the survival of corn rootworms. DIMBOA had no plant independent effect on these corn rootworms weight gain.
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Title: SYNTHESIS AND APPLICATION OF ORGANOMETALLIC PRECURSORS FOR TUNGSTEN AND MOLYBDENUM SULFIDE
Creator: Liu, Bo
Date: 2021
Description: Transition metal chalcogenides (TMCs) have unique properties. They are promising materials for the next generation electrical devices due to...
Show moreTransition metal chalcogenides (TMCs) have unique properties. They are promising materials for the next generation electrical devices due to their suitable band gap, outstanding electron mobility, and controllable atomic thickness. In the last few decades, atomic layer deposition (ALD) has been one of the hottest research frontiers for the fabrication of TMCs films. Signification progress has been made on the varieties of material grown by ALD and the improvement of ALD equipment. However, the fast-evolving microelectronic industry set higher requirements for the ALD application. In the potential electronic fabrication process, low-temperature preparation and non-corrosive procedure are critical for the advanced device architecture. Thus the novel precursor development and the investigation of reaction mechanism are necessary. In addition, as the comprehensive research of film deposition, the prevailing crystallographic defects on the as-prepared films are another appealing thing for us to think about and try to eliminate for better film quality. Therefore, this dissertation will describe the precursor ligand design and its effect on the morphology, the development of W/Mo precursors for tungsten/molybdenum disulfide, and the defect passivation of tungsten diselenide films.In chapter 2, a series of heteroleptic tungsten precursors of tetrathiotungstates (WS42-) were prepared through the facile ligand transfer method. Ligand variation has a significant effect on the crystallinity of the resulting tetrathiotungstate products. Crystalline tetrathiotungstates with preferred orientation were prepared from the reaction of synthesized precursors with H2S at room temperature. Results indicated the morphologies and crystallinities of the tetrathiotungstates can be well controlled by their ligand behaviors which give us a better understanding of the growth mechanism. Chapters 3 and 4 focus on the development of W and Mo precursors for W/Mo disulfide and their performance in wet chemistry reactions and ALD. WS2 can be synthesized at the ambient temperature in solution by the non-redox reaction. WS2 film growth can be achieved at the exciting low temperature of 125°C by ALD. Based on the performance of the tungsten precursor, a new molybdenum dimer precursor with improved reactivity was synthesized, and MoSx can be prepared at the ambient temperature in seconds. X-ray absorption spectroscopy (XAS) was also utilized to investigate the interaction between the organometallic precursor and the SiO2 surface. Chapter 5 will focus on the defect passivation of WSe2 films for the improvement of their electrical performance. Precursors were synthesized, and the wet chemistry method was designed for oxidation removal and vacancy healing. Raman spectroscopy was used as the express characterization method to reveal the treatment results. A promising healing reagent was screened out, and the repaired films were fabricated to field-effect transistors (FETs) for electrical measurements. The final results showed the electrical performance of the WSe2 films was improved after the convenient chemical treatment.
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Title: DO GENERAL EDUCATION HIGH SCHOOL STUDENTS IN A BASIC PHYSICAL SCIENCE COURSE IMPROVE UPON ATTITUDES TOWARD SCIENCE LEARNING AND CONTENT MASTERY FOLLOWING VIRTUAL/REMOTE FLIPPED INSTRUCTION OR VIRTUAL/REMOTE NON – FLIPPED INQUIRY – BASED INSTRUCTION?
Creator: Martino, Robert S.
Date: 2022
Description: As we progress further into the 21st Century, high school science is being challenged on how to best deliver instruction to students. Teacher ...
Show moreAs we progress further into the 21st Century, high school science is being challenged on how to best deliver instruction to students. Teacher – centered instruction has long been de – emphasized in favor of inquiry – based instruction, although teacher – centered instruction still exists to a noticeable extent. Inquiry – based instruction, while more student – centered in its common practice, still involves the teacher as a guide during classroom direct instruction. Research has been ongoing to identify new and dynamic forms of science concept delivery that serve the needs of diversified science instruction (Keys & Bryan, 2001; Saldanha, 2007). Virtual instruction has become more commonplace, and it was fully implemented during this study. It has become incumbent upon science education researchers to explore and identify the most effective means of virtual instruction, means that are student – centered, engaging, interesting, and that both improve student science content understanding and attitudes toward science. Flipped instruction is a more recently – incorporated form of student – centered instruction that has students experiencing classroom routines at home and homework routines in class, and that is why this instruction is referred to as being “flipped.” Hunley (2016) examined teacher and student perception of flipped instruction in a science classroom, while Howell (2013) explored it in a ninth – grade physical science honors classroom. At the onset of this study, relatively few studies were available about this newer form of instruction within high school science instruction, no studies were available that involved high school general education physical science courses, and certainly no studies were available that compared virtual/flipped and non – flipped general education physical science instruction at the onset of this study. This study researched the effect of virtually – implemented flipped instruction on high school students’ understanding and attitude toward science. Instruction was completely virtual/remote (online), and at home, for all students in this study. In investigating the effect of this type of instruction, this study examined student academic performance and attitudes (and intentions and beliefs) toward science in two units of a high school Integrated Chemistry and Physics (Physical Science) course. Sixty – six students from Southlake High School, a midwestern U.S. high school, took part in the study. Sixty – four of those students took the unit assessments. Half of the students (test group) were instructed via virtual/remote flipped instruction and the other half (control group) were instructed via virtual/remote non – flipped, inquiry – based instruction during the first unit. During the second unit, the test group students who were instructed via virtual/remote flipped instruction switched with the control group and were instructed via virtual/remote non-flipped inquiry – based instruction, while the control group students who were instructed via virtual/remote non-flipped instruction were instructed via virtual/remote flipped instruction. The students in both groups were surveyed three times, using the Behaviors, Related Attitudes, and Intentions Toward Science (BRAINS) (Summers, 2016) instrument student questionnaire and survey for their attitudes (and beliefs and intentions) toward science (once prior to the first unit, once after the first unit, and once following the second unit). Student test results and survey responses were then analyzed to identify which instructional style was more effective for student learning and whether student attitudes (and intentions, and beliefs) favored one instructional style over the other. Student science attitudes (and beliefs and intentions) and academic performance were evaluated throughout the study. There was an increase in control group student science attitudes (and beliefs and intentions), from the pre – study survey to the post – unit 1 survey following their receipt of non – flipped virtual/remote instruction in the first unit. There was a lower increase in test group student science attitudes (and beliefs and intentions), from lower pre – study attitudes (compared with the control group) following the test group’s receipt of flipped virtual/remote instruction in the first unit,. Following the second unit, both the control group and test group again showed increases in attitude (and beliefs and intentions) compared with the pre – study survey results, with the control group again showing greater increases than the study group. Student academic performance favored the control group as it outperformed the test group in both the first unit and the second unit, even when the test group received the virtually – delivered flipped instruction in the first unit. The findings of the study showed that virtually implemented flipped instruction resulted in no advantage for the test group in terms of greater improvement in attitudes (or beliefs or intentions) toward science and no advantage for the test group in terms of learning science content in general education Integrated Chemistry and Physics (Physical Science). These results indicate that this form of teaching may not be effective in improving general education Physical Science student learning and student attitudes (and beliefs and intentions) toward science. Therefore, the use of virtually implemented flipped instruction in this general education science course will need to be further studied to determine its effect on student learning and student attitudes (or even beliefs and intentions) toward science.
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Title: Sensemaking for Power Asymmetries in Anti-Oppressive Design Practice
Creator: Meharry, Jessica J
Date: 2022
Description: Within professional design practice in capitalist market contexts, the goals of user-centered and human-centered design methodologies is to...
Show moreWithin professional design practice in capitalist market contexts, the goals of user-centered and human-centered design methodologies is to make algorithmically-based technologies understandable for users, satisfy customer needs and desires, and thereby increase corporate profitability. However, there is growing concern that the computational methods, data management, and business models that drive these technologies are leading to global asymmetries of knowledge, information, and power. The asymmetries of power generated by these designed interactions can be considered the kind of wicked problem that design seeks to address. Yet the dominant goals and methods of professional design practice limit their ability to design ethically within market contexts. These methodologies fail to adequately consider systemic context and power relations, potential for bias in algorithmic computation, and specific forms of systemic oppression. These gaps then lead to inadequate design solutions. This study explores these gaps in design methodologies that could be transferable to a range of professional (and non-professional) practices by looking at potential new levers within familiar design methods and their effectiveness as facilitating problem reframing towards equitable solutions. This dissertation advances knowledge in design by exploring how professional designers can better understand how to use sensemaking processes for salience of power asymmetries, algorithmic materiality, and systemic oppression. It proposes an anti-oppressive design framework that is rooted in a critically-informed design praxis. These orientations rethink and recreate design knowledge by helping professional designers shift the market-focused paradigm for which they are designing.
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