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Title: Stephen Fienberg's influence on algebraic statistics, Special Volume in honor of memory of S.E.Fienberg
Creator: Petrović, Sonja, Slavkovic, Aleksandra, Yoshida, Ruriko
Date: 2019, 2019-04-12
Description: Stephen (Steve) E. Fienberg (1942-2016) was an eminent statistician, whose impact on research, education and the practice of statistics, and...
Show moreStephen (Steve) E. Fienberg (1942-2016) was an eminent statistician, whose impact on research, education and the practice of statistics, and many other fields is astonishing in its breadth. He was a visionary when it came to linking many different areas to address real scientific issues. He professed the importance of statistics in many disciplines, but recognized that true interdisciplinary work requires joining of the expertise across different areas, and it is in this spirit that he helped steer algebraic statistics toward becoming a thriving subject. Many of his favorite topics in the area are covered in this special issue. We are grateful to all authors for contributing to this volume to honor him and his influence on the field. During the preparation of this issue, we learned about the tragic killing of his widow, Joyce Fienberg, during the Tree of Life Synagogue massacre in Pittsburgh, PA on October 27, 2018. This issue is dedicated to their memory.
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Collection: Journal of Algebraic Statistics

Title: Sketchbook 4: Meetings 2001
Creator: Gordon, Robert Philip
Date: 2001
Description: Sketchbook containing sketches of various Mayor's Committee meetings, including the Streetscape Committee, Parks & Open Space Committee, and...
Show moreSketchbook containing sketches of various Mayor's Committee meetings, including the Streetscape Committee, Parks & Open Space Committee, and Landscape Task Force. The sketches date from February to July 2001, and include such projects as Soldier Field and the "Central Area," Jackson Park, Grant Park, and the 31st Street overpass. One sketch includes an unbuilt Santiago Calatrava design for a pedestrian bridge at Queen's Landing in Grant Park.
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Collection: Robert Philip Gordon papers, 1963-2010

Title: Mermel House
Creator: Gordon, Robert Philip
Date: 1976
Description: Full color architectural sketch of the Mermel House, in the Kenwood neighborhood of Chicago.
Collection: Robert Philip Gordon papers, 1963-2010

Title: Mermel House
Creator: Gordon, Robert Philip
Date: 1976
Description: Full color architectural sketch of the Mermel House, in the Kenwood neighborhood of Chicago.
Collection: Robert Philip Gordon papers, 1963-2010

Title: Alternatives for Planning - Kenwood Oakland
Creator: Gordon, Robert Philip
Date: 1968-03
Description: Spiral-bound facsimile of Alternatives For Planning, a booklet designed and compiled by Robert Gordon for the Kenwood-Oakland Community...
Show moreSpiral-bound facsimile of Alternatives For Planning, a booklet designed and compiled by Robert Gordon for the Kenwood-Oakland Community Organization (KOCO) in March, 1986, with plans by Robert Gordon. The page order in the facsimile copy does not match the order in the original booklet; the pages have been reordered here to match the order of the original booklet.
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Collection: Robert Philip Gordon papers, 1963-2010

Title: San Bar house - East elevation
Creator: Gordon, Robert Philip
Date: 1979-04-13
Description: Color sketch of the east elevation of a home designed for the San Bar Beach community of South Haven, Michigan.
Collection: Robert Philip Gordon papers, 1963-2010

Title: San Bar house - Plan
Creator: Gordon, Robert Philip
Date: 1979-04-13
Description: Floor plan of a home designed for the San Bar Beach community of South Haven, Michigan.
Collection: Robert Philip Gordon papers, 1963-2010

Title: San Bar house - East elevation
Creator: Gordon, Robert Philip
Date: 1979-04-16
Description: Color sketch of the east elevation of a home designed for the San Bar Beach community of South Haven, Michigan.
Collection: Robert Philip Gordon papers, 1963-2010

Title: Walton Carpets Exterior, ca. 1976
Creator: Gordon, Robert Philip
Date: 1976
Description: Photograph of the exterior of Walton Carpets designed by Robert Gordon. Date of photograph is unknown. Date listed is approximate.
Collection: Robert Philip Gordon papers, 1963-2010

Title: Uptown Theater District painting, 1997
Creator: Gordon, Robert Philip
Date: 1997-03
Description: Watercolor painting completed as part of a proposal for the renovation of the Uptown Theatre and development of the Uptown theater district in...
Show moreWatercolor painting completed as part of a proposal for the renovation of the Uptown Theatre and development of the Uptown theater district in the Uptown neighborhood of Chicago.
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Collection: Robert Philip Gordon papers, 1963-2010

Title: Uptown Theater District painting, 1997
Creator: Gordon, Robert Philip
Date: 1997-03
Description: Watercolor painting completed as part of a proposal for the renovation of the Uptown Theatre and development of the Uptown theater district in...
Show moreWatercolor painting completed as part of a proposal for the renovation of the Uptown Theatre and development of the Uptown theater district in the Uptown neighborhood of Chicago.
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Collection: Robert Philip Gordon papers, 1963-2010

Title: San Bar Beach - Cottage
Creator: Gordon, Robert Philip
Date: 1980
Description: Watercolor painting of a cottage in the San Bar Beach community of South Haven, Michigan. Date listed is approximate.
Collection: Robert Philip Gordon papers, 1963-2010

Title: USING COMPUTATIONAL MOLECULAR MODELING TO STUDY TRANSPORT PROCESSES OF INTEREST IN SEPARATIONS
Creator: Wang,Xiaoyu
Date: 2020, 2020
Publisher: ProQuest
Description: Separation processes are widely used in chemical productions. The further development of membrane-based separation processes, compared with...
Show moreSeparation processes are widely used in chemical productions. The further development of membrane-based separation processes, compared with thermal separations, can lead to significant energy savings in chemical process industries. However, the main obstacle of experiments is that many separation processes are not well understood at the fundamental molecular level. In this dissertation, we use computational molecular modeling tools, mainly classical molecular dynamics (MD), to clarify molecular forces and provide detail at a molecular level, which can aid in the understanding of transport process and designing materials for a proposed application. In the first study, we investigated separation of water/alcohol vapor using zeolite membranes. Experimentally, the separation of water/isopropanol (IPA) mixtures shows a dramatic decrease in selectivity due to increase of IPA flux as the feed water concentration decrease when using the sodium A zeolite membrane. We used molecular dynamics simulations to help our experimental collaborators understand these puzzling results. The MD results reveal that the water molecules gather around the defect pores on the zeolite membrane, which stops the IPA from going through the membrane and has a positive effect on separation. Then, we studied the HPLC used to separate chiral drug mixtures. One popular chiral stationary phase, amylose tris(3,5-dimethylphenyl carbamate) (ADMPC), has been investigated using both experimental and computational methods; however, the dynamic nature of the interaction between enantiomers and ADMPC, as well as the solvent effects on the ADMPC-enantiomer interaction, are currently absent from the chiral recognition mechanism. We used MD simulations to model the ADMPC in different solvents to elucidate the chiral recognition mechanism from a new dynamic perspective. The ADMPC is found to hold the left-handed helical structure in both methanol and heptane/IPA (90/10); however, the ADMPC has a more extended average structure in heptane/IPA. We developed a model where the ADMPC atoms were restricted in the MD simulation. To better understand the molecular dynamic chiral recognition that provides the retention factor and the elution order in HPLC, we examined hydrogen bonding lifetimes, and mapped out ring-ring interactions between the drugs and the ADMPC. We discover several MD metrics related to hydrogen-bonding lifetimes and correlate them with HPLC results. One metric provides a prediction of the correct elution order 90%, and the ratios of these quantities for the enantiomers provide linear correlation (0.85 coefficient) with experimental retention factors. In the following study, we presented an improved model wherein multiple ADMPC polymer strands are coated on an amorphous silica slab. Using various MD techniques, we successfully coated ADMPCs onto the surface without losing the structural character of the backbone in the solvent. This model provides more opportunities for chiral molecules interacting with ADMPC, resulting in a better agreement compared with experiment when using the overall average metric. The new model also provides the possibility for drug molecules to interact with two polymer strands simultaneously, which is not possible in the previous single-strand model. For a better understanding of why some metrics are better predictors than others, we used charts of the distribution of hydrogen bonding lifetimes to display the information for various donor-acceptor pairs. The results are more consistent than the previous models and resolves the problematic cases of thalidomide and valsartan. Besides the membrane-based separations, immiscible liquid-liquid equilibrium states were also studied. We successfully predicted results based on MD simulations and showed comparable accuracy with experimental data. This method has applications in liquid-liquid extraction which is widely used in industrial separation process.
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Title: Modeling enantiomeric separations as an interfacial process using amylose tris(3,5-dimethylphenyl carbamate) (ADMPC) polymers coated on amorphous silica
Creator: Wang,Xiaoyu, Jameson, Cynthia, Murad, Sohail
Date: 2020, 2020-01-20
Publisher: ACS Langmuir
Description: In the present study, we present a model to predict the chiral separation results for drug enantiomers by ADMPC chiral stationary phase in...
Show moreIn the present study, we present a model to predict the chiral separation results for drug enantiomers by ADMPC chiral stationary phase in high performance liquid chromatography (HPLC) wherein multiple ADMPC polymer strands are coated on an amorphous silica slab. Both reactive and classical MD are used to prepare the surface. Using various MD techniques, we successfully coat ADMPCs onto the surface without losing the structural character of the backbone in the presence of the solvent system. Not only is this model more representative of the polymer surface on a solid support that is encountered by the enantiomers, it also provides more opportunities for chiral molecules interacting with ADMPC, resulting in a better agreement compared with experiment when we use overall average quantities as the metric. In our previous studies, we had used a single polymer strand of amylose tris(3,5-dimethylphenyl carbamate) (ADMPC) in the solvent system. The new model provides the possibility for large drug molecules to interact with two polymer strands at the same instant, which was not possible to model with only a single polymer strand in the solvent. For a better understanding of why some metrics are better predictors than others, we use charts of the distribution of hydrogen bonding lifetimes in this work to display the hydrogen-bonding information for various donor-acceptor pairs that contribute to the interaction events determining the relative retention times for the enantiomers. We also examine the contribution of the ring-ring interactions to the molecular recognition process and ultimately to differential retention of S and R enantiomers. The results using the new model are more consistent than the previous models and resolves the problematic case of two drugs, thalidomide and valsartan.
Sponsorship: The National Science Foundation (CBET 1545560)
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Title: Leveraging the flexibility of Islandora to create a dual-use digital repository
Creator: Esquivel, Alicia, Fluhr, Tim, Strohm, Adam
Date: 2021, 2021
Publisher: Henry Stewart Publications
Collection: Journal of Digital Media Management

Title: Investigation of Novel Solid Polymer Electrolytes and Lithium Salts for Rechargeable Lithium Batteries
Creator: Zhao, Wendy
Date: 2021
Description: Lithium-ion batteries (LIBs) are extensively used in many consumer electronic products. LIBs have great potential for application in electric...
Show moreLithium-ion batteries (LIBs) are extensively used in many consumer electronic products. LIBs have great potential for application in electric vehicles by virtue of their high power density and charge cycles. Research and development in this area has been focused on all around the globe. The major challenges include high cost, safety issues of the solvent based electrolytes, and low conductivities at ambient temperature of the solid polymer electrolytes (SPEs).This dissertation describes four novel electrolyte systems and a series of low lattice energy lithium salts synthesized and characterized for applications in LIBs. First, a new SPE has been derived from oligomeric poly(ethylene oxide) (PEO)-grafted crosslinked polystyrene (XPS) microspheres containing 1-2 lithium sulfonate moieties. This SPE possesses amorphous character with a glass transition temperature (Tg) around 135 ºC, displayed a good electrochemical stability with excellent ionic conductivity in excess of 10^-4 S/cm at 25ºC, and no significant thermal decomposition until 420 ºC. Second, a hybrid composite polymer electrolyte (CPE) was constructed with a gel matrix formed through hydrogen bonding by incorporating nanoparticles of fumed silica into the nanoscale network of PEO-XPS. Fumed silica with large surface modification group like polysiloxane formed an ideal gel structure offering significant high mechanical strength above 10^4 Pa, and a good ionic conductivity at 25°C. Third, a nonvolatile x-linked gel membrane electrolyte was synthesized with amino methacrylate, to introduce hemi-labile ligands as ionic liquid, into the polymer network. This new material exhibited improved salt solubility and ionic conductivity, due to the fast ligand exchange that facilitates the lithium ion structural transport, and also displayed an excellent electrochemical stability(4.8 V vs, Li/Li+). Fourth, a self-healing and thermal reversible polymer electrolyte designed based on Diels-Alder conjugation between multi-maleimides (2M-3M) and multi-furans (2F-4F) was synthesized. The reversible x-linking was realized through Diels-Alder (DA) and Retro-DA reactions by applying heating (>130°C)/cooling (<90°C) cycles. Last, new lithium salts with star and branch structures containing 1-4 of imide or methide moieties were synthesized and evaluated in PEO electrolyte system. These salts demonstrated good ambient temperature ionic conductivity at low concentrations, and the electrochemical stabilities were equal to or better than the most commonly used lithium salt, lithium bis(trifluoromethanesulfonyl)imide (LiTFSI). Synthesis and characterization, including electrochemical properties, thermal and electrochemical stabilities, mechanical behaviors and surface morphologies of these new materials are described and discussed.
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Title: BLOCKCHAIN FOR TRANSACTIVE ENERGY MARKET WITH NETWORKED MICROGRIDS
Creator: Yan, Mingyu
Date: 2021
Description: Transactive energy, which allows and incentivizes microgrids (MGs) to trade energy with each other, is regarded as the next-generation energy...
Show moreTransactive energy, which allows and incentivizes microgrids (MGs) to trade energy with each other, is regarded as the next-generation energy management scheme to accommodate the penetration of distributed energy resources (DERs). Blockchain provides an effective and decentralized strategy, which can address the operational challenges introduced by the transactive energy market. This thesis is aimed at providing effective transactive energy markets for incentivizing MGs to trade energy and utilizing blockchain technologies to provide a secure and efficient energy trading environment for all participants.First, this thesis offers a centralized transactive market for networked MGs to transact energy through the centralized distribution system operator (DSO) while ensuring the power network limits. All MGs cooperate in this market and the cooperative behaviors are captured using the cooperative game with externalities. A two-level problem is studied to allocate the total payoff to all participating MGs. Numerical results for a 4-MG system and the IEEE 33-bus show the validity of the centralized transactive energy model. Second, this thesis proposes a two-level network-constrained peer-to-peer (P2P) transactive energy for multi-MGs, which guarantees the distribution power network security and allows MGs to trade energy with each other flexibly. At the lower level, a P2P transactive energy is employed for multi-MGs to trade energy with each other. A multi-leader multi-follower (MLMF) Stackelberg game approach is utilized to model the energy trading process among MGs. At the upper level, the DSO reconfigures the distribution network based on the P2P transactive energy trading results by applying the AC optimal power flow considering the distribution network reconfiguration. If there are any network violations, the DSO requests energy trading adjustments at the lower level for network security. Numerical results for a 4-MG system, the modified IEEE 33-bus, and the 123-bus distribution power systems show the effectiveness of the proposed transactive energy model and its solution technique. Third, this thesis adopts the blockchain for the peer-to-peer transactive energy market among MGs. A two-level integrated blockchain-power system is provided, in which all MGs and the DSO are equipped with blockchain. At the lower level, MGs trade energy with each other through the lower-level MG blockchain, while the DSO manages the network security through the upper level DSO blockchain. We illustrate how to utilize blockchain technologies, i.e., public and private keys and smart contracts, to provide an efficient and secure energy trading environment for all MGs. Last, this thesis applies the blockchain for transacting energy and carbon right for networked MGs. MGs transact energy and carbon right through the centralized DSO while ensuring the power network limits. The introduction of blockchain achieves secure and decentralized market settlements in this centralized market. Numerical results for a 4-MG system and modified IEEE 33-bus systems show the effectiveness of the proposed transactive energy and carbon market.
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Title: IMPROVING DEEP LEARNING BASED SEMANTIC SEGMENTATION USING CONTEXT INFORMATION
Creator: Xia, Zhengyu
Date: 2021
Description: Semantic segmentation is an important but challenging task in computer vision because it aims to assign each pixel a category label accurately...
Show moreSemantic segmentation is an important but challenging task in computer vision because it aims to assign each pixel a category label accurately. Nowadays, applications such as autonomous driving, path navigation, image search engine, or augmented reality require accurate semantic analysis and efficient segmentation mechanisms. In this thesis, we propose multiple models to improve the performance of semantic segmentation. In the first part, we focus on the single-task network, which aims to improve the performance of semantic segmentation. Our research includes exploiting context information using mixed spatial pyramid pooling to extract dense context-embedded features in FCN-based semantic segmentation. We also propose a GAF module to generate a global context-based attention map to guide the shallow-layer feature maps for better pixel localization. In the second part, we focus on a multi-task network that incorporates semantic segmentation to improve other computer vision tasks such as object detection. Specifically, a multi-task network, along with a learning strategy is designed to let semantic segmentation and object detection assist each other since they are highly correlated. Also, we include weakly-supervised multi-label semantic segmentation learning to deal with the shortage of high-quality training examples and to improve the performance of cross-domain object detection. In the third part, we focus on improving the performance of video panoptic segmentation, which is a unified network that incorporates semantic segmentation and instance segmentation using video streams. We design a new ConvLSTM pyramid to transmit spatio-temporal contextual information in our video panoptic segmentation network. Specifically, we propose a modified ConvLSTM to generate temporal contextual information. Also, we design an MSTPP module to obtain mixed spatio-temporal context-embedded feature maps. Experimental results on different datasets show that our proposed method achieves better performance compared with the state-of-the-art methods.
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Title: ANALYTIC STUDY OF THE CELLULAR FUNCTIONS OF UBL4A
Creator: Zhang, Huaiyuan
Date: 2021
Description: Ubiquitin-like protein 4A (Ubl4A) is a small protein encoded by a “housekeeping” gene that locates on the X chromosome. As a multi-functional...
Show moreUbiquitin-like protein 4A (Ubl4A) is a small protein encoded by a “housekeeping” gene that locates on the X chromosome. As a multi-functional protein, it has roles in a variety of cellular events including anti-tumorigenesis, response to DNA damage, inhibiting the fusion between autophagosome and lysosome, and docking of the tail-anchored proteins to the endoplasmic reticulum. We have previously reported that the newborns from Ubl4A-deficient mice had a high rate of mortality due to defect of AKT-dependent glucose metabolism. At the molecular level, Ubl4A directly binds with the actin related protein (Arp) 2/3 complex to accelerate the building up of the actin branching network, which further promotes the translocation and activation of the Akt, a key kinase for multiple cellular processes, from the cytosol to the plasma membrane.In further exploration of the molecular basis of Ubl4A in cell survival, here, we demonstrated that Ubl4A is critical for mitochondrial fusion and cell survival under nutrient depletion. In WT (wild-type) cells, the association of Ubl4A and the Arp2/3 complex serves as a primed “pool” of the actin branching network near mitochondria and enables mitochondria to fuse quickly for energy conservation upon starvation insult. However, such a “ready-to-go pool” of mitochondria was significantly decreased in the Ubl4A-deficient cells. As the result, the mitochondria became fragmentated, exhibited decreased trans-membrane potential, and accumulated ROS (reactive oxygen species), consequently, initiated mitochondria-mediated apoptosis. In this study, we also observed that Ubl4A-deficient mice displayed type II diabetic phenotype under a high-fat diet feeding. The preliminary results showed that these Ubl4A-deficient mice were more sensitive to glucose intolerance than their WT littermates, most likely owing to a delay in glucose uptake, and/or insulin secretion, both of which require the Arp2/3-actin branching network. We speculated that Ubl4A might be involved in cellular vesicle formation and/or secretion, but further investigation is needed to approve this hypothesis. Taken together, these findings provide a novel function of Ubl4A and further insight into the multi-functional roles of Ubl4A in mammalian cells, as well as the molecular basis for understanding the clinical relevance of Ubl4A in related human diseases.
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Title: Fate of Listeria Monocytogenes on Hard-cooked Eggs Treated With Citric Acid
Creator: Zeng, Hui
Date: 2021
Description: Commercially-prepared hard-cooked eggs are available for foodservice and to the public in retail grocers. Potential contamination with...
Show moreCommercially-prepared hard-cooked eggs are available for foodservice and to the public in retail grocers. Potential contamination with Listeria monocytogenes during or after the cooking and peeling steps is of concern since this pathogen can proliferate at refrigeration temperatures. Citric acid is a common preservative used in the food industry to treat hard-boiled eggs (HBEs). The purpose of this project was to evaluate the efficacy of citric acid treatment of HBEs to reduce the population levels of L. monocytogenes during 24 h (treatment trials) and 28 d storage (storage trials) at 5 or 25°C. Fresh eggs were boiled for 12 min, cooled to 4°C, peeled, and stored at 5°C for 24 h prior to experiments. In treatment trials, HBEs were dip inoculated with a 4-strain cocktail of rifampicin-resistant L. monocytogenes resulting in either 4 (low) or 7 (high) log CFU/egg. Eggs were air-dried 10 min, followed by treatment with pH 2.5 citric acid (PHCA) or 0.2 M citric acid (calculated as the molarity resulting in pH 2.5: MCA) at 5 or 25°C for 24 h. In treatment-storage trials, citric acid treatment of HBEs occurred before or after inoculation, followed by 28-d storage at 5 or 25°C. L. monocytogenes populations were enumerated by homogenization of eggs with BLEB and cultivation on BHI/rifampicin agar. Enrichment in BLEB was conducted if the pathogen was below the level of enumeration. Significant differences in the populations of L. monocytogenes due to temperature of the acid treatment (5 or 25°C) or the two citric acids (MCA and PHCA) were determined using Student’s T-test and ANOVA with Tukey’s post-test, p ≤ 0.05. Overall, the largest L. monocytogenes reduction occurred after 6 h treatment of HBEs with PHCA at 25°C (1.59 ± 0.00 log CFU/egg) and after 24 h with MCA at 5°C (1.23 ± 0.54 log CFU/egg) when the pathogen was inoculated at the low and high levels, respectively. In treatment-storage trials, citric acid treatment after HBE contamination resulted in a fewer number of samples where the pathogen was detected compared to when treatment occurred before contamination. Citric acid treatment for 24 h also resulted in a greater number of samples where L. monocytogenes was not detected than the 1 h treatment. The results of this study determined that L. monocytogenes could survive on HBEs treated with citric acid, regardless of treatment or storage temperature and acid concentration (PHCA or MCA).
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