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(121 - 140 of 5,649)
Pages
- Title
- Rehabilitation of "Kumbharwada", Dharavi Slums, Mumbai
- Creator
- Purandare, Bhakti
- Date
- 2010-05-01, 2010-05-01
- Description
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Within the slums of India small and unventilated dwellings serve as multipurpose spaces where a families live as well as manufactures pottery...
Show moreWithin the slums of India small and unventilated dwellings serve as multipurpose spaces where a families live as well as manufactures pottery products. In terms of production mechanisms, potter’s depend on conventional kilns which are shared between families. They use cotton dust, rags /wastes and diesel & oil soaked cotton as firing fuel which is serious cause of population & health hazards.
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- Title
- Method and Apparatus for Producing Fibers from Molten Metals or Ceramics
- Creator
- Howes, Maurice A. H., Schwartzbart, Harry
- Date
- 4/24/2009, 1970-03-17
- Description
-
Sponsorship: IIT Research Institute
United States Patent
- Title
- ISOLATION OF MONOSPECIFIC ANTIBODY AGAINST SPLICED VARIANT OF DYSTROPHIN PROTEIN USING YEAST SURFACE DISPLAY TECHNIQUE
- Creator
- Saraswathi, Raj Prabu Vijayakumar
- Date
- 2011-05-04, 2011-05
- Description
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Dystrophin gene is the largest in the human genome with 79 exons covering greater than 0.1% of the total genome, located on the Xp21 locus of...
Show moreDystrophin gene is the largest in the human genome with 79 exons covering greater than 0.1% of the total genome, located on the Xp21 locus of the “X” chromosome resulting in a 427kDa protein, “Dystrophin”. Dystrophin is an important cytoskeletal protein which belongs to the β-Spectrin/α-actinin family of proteins. It comprises of an amino terminal domain, alpha helical coiled structure COOH domain, central rod region with 24 STRs and four proline rich hinge regions. It plays a vital role in localizing the Dystrophin glycoprotein complex (DGC) in the Sarcollema and is associated with the DGC in controlling the signaling events of certain proteins associated with DGC. The large size of the gene makes it more vulnerable to mutations resulting in partially functional or non-functional Dystrophin. The absence of Dystrophin results in disruption of sub sarcolemma-extracellular matrix linkage, loss of nitric oxide, progressive muscle weakening and muscle wasting leading to the death of patients typically before the end of their teenage. In certain cases alternatively spliced isoforms produce Dystrophin with reduced length yet stable and completely functionality. The main focus of this project was to select monospecific antibody against the more stable alternatively spliced variant D14 (15”16”) 17, which is functional and more stable compared to unspliced parent D14:17. The yeast surface display technique was used to effectively screen and select the yeast scFv clones containing the monospecific antibody against our target spliced variant D14 (15”16”) 17 protein and D2:3. The yeast scFv sub population was enriched by repeated MACS and FACS selection. Test colonies picked from the enriched scFv pool were confirmed via PCR and restriction digestion analysis. The scFv for the respective antigens were then sub cloned into pPnnl-9 secretion vector using YVH10 yeast cells via LiTRAFCO method. It was clear that by repeated MACS and FACS selection the scFv pool can be enriched and the yeast scFv clone sub population can be reduced to a significant level. The scFv sub cloned into Pnnl-9 secretion vector can be purified using affinity chromatography and the further affinity and avidity studies can be conducted.
M.S. in Biology, May 2011
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- Title
- Video Transducer System with Magnetic Transducer Head Having Output Winding Means Resonant at a Mid Band Resonance Frequency
- Creator
- Camras, Marvin
- Date
- 2009-05-04, 1975-03-11
- Description
-
A wideband transducer system including longitudinally recorded video, transversely recorded or multiplexed audio, channel shifting during...
Show moreA wideband transducer system including longitudinally recorded video, transversely recorded or multiplexed audio, channel shifting during blanking intervals, high frequency bias synchronized to audio carrier frequency or otherwise selected to avoid beat notes, head with plural windings switched to reduce inductance during recording and connected for wideband playback into an amplifier input with comparable or higher impedance than that of the winding.
Sponsorship: IIT Research Institute
United States Patent
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- Title
- Multivariable MPC system performance assessment, monitoring, and diagnosis
- Creator
- Schaffer, J., Cinar, A.
- Date
- 2004-03
- Publisher
- ELSEVIER SCI LTD
- Description
-
This study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a...
Show moreThis study focuses on performance assessment and monitoring of model predictive control systems. A methodology is proposed to determine a benchmark and monitor model predictive control performance on-line. A performance measure based on the ratio of historical and achieved performance is used for monitoring and a ratio of design and achieved performance is used for diagnosis. Performance monitoring and diagnosis of causes for poor performance are integrated. A real-time knowledge-based system is developed to supervise monitoring and diagnosis activities. Case studies with linear and nonlinear models of an evaporator illustrate the methodology and limitations of linearity assumptions.
Endnote format citation for DOI:10.1016/j.jprocont.2003.07.003
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- Title
- Dry Alkali Chlorotitanates and Method of Making the Same
- Creator
- Schossberger, Frederic V.
- Date
- 1958-10-21
- Description
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Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Multivariate statistical methods for monitoring continuous processes: Assessment of discrimination power of disturbance models and diagnosis of multiple disturbances
- Creator
- Raich, A. C., Cinar, A.
- Date
- 1995-11
- Publisher
- ELSEVIER SCIENCE BV
- Description
-
A new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine...
Show moreA new methodology was reported [1,2] for integrated use of principal components analysis (PCA) and discriminant analysis in order to determine out-of-control status of a continuous process and to diagnose the source causes for abnormal behavior. Most of the disturbances were identified with good rates of success, with a higher success rate for step or ramp type of disturbances. Quantitative tools that evaluate overlap and similarity between high-dimensional PCA models are proposed in this communication, and their implications on determining the discrimination power of PCA models of processes operating under disturbances are discussed. Diagnosis of several disturbances occurring simultaneously is also investigated. The criterion developed provide upper limits of discrimination power of various single and multiple process disturbances. The techniques developed are illustrated by assessing the process described by the Tennessee Eastman Control Challenge problem [3].
Endnote format citation
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- Title
- PARAMETRIC IMAGE ESTIMATION IN ANALYZER-BASED PHASE CONTRAST IMAGING
- Creator
- Caudevilla, Oriol
- Date
- 2014, 2014-07
- Description
-
Since the discovery of X-rays, by W.E. Roentgen in 1895, absorption-contrast imaging has been widely used in medical diagnostic, for example:...
Show moreSince the discovery of X-rays, by W.E. Roentgen in 1895, absorption-contrast imaging has been widely used in medical diagnostic, for example: mammography, chest X-ray, angiography etc. Over the last 25 years many researchers have shown that phase-contrast X-ray imaging is capable of obtaining a better contrast then classical absorption-contrast imaging. This is especially true in soft tissue imaging like mammography or at higher Xrays energies. During the past five years a significant effort has made in development of a tabletop analyzer-based phase-contrast system. In this system a perfect crystal is used to generate a quasi-monochromatic beam, which after interacting with an object is analyzed by a second perfect crystal called analyzer. The need of quasi-monochromatic beam and the low brilliance of conventional X-ray sources (CXS) has been the major limiting factor for tabletop systems. The work presents in this thesis aims to develop novel reconstruction methods for tabletop analyzer-based phase-contrast imaging (ABI) systems. The presented reconstruction methods goal is to minimize the impact of CXS low brilliance by utilizing phase-contrast image formation model and maximum or maximum-a-posteriori Poisson likelihood approach. Finally, a fast-convergent conjugate gradient optimization algorithm has been derived specifically for Poisson likelihood function maximization.
M.S. in Electrical Engineering, July 2014
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- Title
- Magnetic Recorder and Reproducer for Video
- Creator
- Camras, Marvin
- Date
- 1959-08-18
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- An Alternative Car Show: An Alternateive Vehicle Insfrastructure
- Creator
- Hopkins, Kyle
- Date
- 2010-07-29
- Title
- NEUTRON PRODUCTION IN THE M2 MUON BEAM LINE AT CERN
- Creator
- Draeger, Emily
- Date
- 2014, 2014-05
- Description
-
Spallation neutrons produced from cosmic ray muons are a major source of backgrounds in underground physics experiments. Experiments have been...
Show moreSpallation neutrons produced from cosmic ray muons are a major source of backgrounds in underground physics experiments. Experiments have been done to study spallation neutron production and yield, but our understanding of these processes is still limited. There are various interactions that can produce spallation neutrons. Most of these production mechanisms are fairly well understood; much of the uncertainty in our understanding of spallation neutrons lies in mechanisms such as virtual photon exchange and the assumptions used to calculate the photonuclear cross section. Even the experiments that have been carried out do not agree with each other or theoretical calculations. Spallation neutron production mechanisms are discussed, as well as a new experiment to study spallation neutrons. The impact of this study on current and future underground physics experiments is also explored.
PH.D in Physics, May 2014
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- Title
- INTELLIGENT PROCESS-CONTROL WITH SUPERVISORY KNOWLEDGE-BASED SYSTEMS
- Creator
- Kendra, S. J., Basila, M. R., Cinar, A.
- Date
- 1994-06
- Description
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The integration of a supervisory knowledge-based system (KBS) with a multivariable control system is examined to provide robust multivariable...
Show moreThe integration of a supervisory knowledge-based system (KBS) with a multivariable control system is examined to provide robust multivariable control of a chemical reaction process. The supervisory KBS is capable of monitoring the process to detect system faults as well as assessing control system performance. If a control system performance deficiency is detected, the KBS formulates and implements the necessary corrective controller tuning. This adaptive capability reduces the conservatism of the robust control system. The underlying mechanisms are discussed and the re-tuning ability of the KBS is illustrated by using rigorous simulations of a chemical reaction process
Endnote format citation
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- Title
- Thermal conductivity
- Creator
- Bauer, W. Ernest, Jr
- Date
- 2009, 1917
- Publisher
- Armour Institute of Technology
- Description
-
http://www.archive.org/details/thermalconductiv00baue
Thesis (B.S.)--Armour Institute of Technology; Includes folded leaves in back pocket
- Title
- Multiple Recorder
- Creator
- Leedy, Haldon A., Camras, Marvin
- Date
- 1950-10-31
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Tape Reel Support
- Creator
- Camras, Marvin
- Date
- 1955-07-19
- Description
-
Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
- Title
- Video Transducing Apparatus
- Creator
- Camras, Marvin
- Date
- 2009-05-04, 1974-06-28
- Description
-
Sponsorship: IIT Research Institute
United States Patent
- Title
- POWER ANALYSIS AND CONTROL OPTIMIZATION OF A HIGH GAIN RESONANT DC-DC CONVERTER
- Creator
- Wu, Haowen
- Date
- 2017, 2017-05
- Description
-
Applications of DC-DC converter require a high power, high efficiency performance, especially for automotive applications and renewable energy...
Show moreApplications of DC-DC converter require a high power, high efficiency performance, especially for automotive applications and renewable energy applications. A desired converter should have a fast response, stable output in different conditions. This thesis studies a novel high gain DC-DC resonant converter and its control. Based on the circuit analysis and operation evaluation, feed-forward and feedback control methods are proposed in order to achieve stability under variety of changes. Moreover, circuit topology is investigated in response to the efficiency improvement. Simulations in PSIM, PLECS and MATLAB Simulink have been carried out to validate the controller design and topology development. The simulation results are in consistence to the theoretical analysis. The overall high efficiency at nominal operating point is further increased.
M.S. in Electrical Engineering, May 2017
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- Title
- NOVEL FAULT DIAGNOSTIC TECHNIQUE AND UNIVERSAL SENSOR FOR PERMANENT MAGNET ELECTRIC MACHINES USING SEARCH COILS
- Creator
- Da, Yao
- Date
- 2012-04-23, 2012-05
- Description
-
Over the past decade, permanent magnet synchronous machines (PMSMs) have gained significant popularity in industry, such as wind turbines and...
Show moreOver the past decade, permanent magnet synchronous machines (PMSMs) have gained significant popularity in industry, such as wind turbines and electric vehicles, owing to their high efficiency, high output power to volume ratio, and high torque to current ratio. In these mission critical applications, an unexpected fault or failure of the machine could lead to very high repair or replacement cost, or even catastrophic system failure. Therefore a robust and reliable health monitoring and fault diagnostic approach is desired, which could help in scheduling preventive maintenance to lengthen their lifespan and avoid machine failure. This dissertation presents a novel multi-faults diagnostic approach using search coils. These search coils are wound around armature teeth, so they typically need to be installed during manufacturing. But its immunity to high frequency harmonics makes it suitable for inverter/rectifier fed motors or generators, such as wind turbines and automotive systems. In addition, this method does not require the knowledge of proprietary constructional details of the machine. Since the electromagnetic flux is directly measured in this method, it provides much more information than any other scheme: the direction of eccentricity and the location of shorted windings. Furthermore, this method is also capable of evaluating the severity of each fault, which is of significant importance in mission critical applications such as automotive, aerospace and military applications. In addition to these uses, the search coils can be used as a universal sensor to estimate phase current or rotor position, which are critical information in a PMSM close-loop control, which allow it to work as a backup sensor for fault tolerant operation. The proposed fault detection scheme and universal sensor concept have been tested under several scenarios with Finite Element Analysis and experimentally validated.
Ph.D. in Electrical Engineering, May 2012
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- Title
- CELL-MATRIX INTERACTIONS IN ADIPOSE TISSUE FUNCTION
- Creator
- Vaicik, Marcella K.
- Date
- 2015, 2015-07
- Description
-
The overall goal of this work is to apply in vivo and in vitro models to study the basement membrane protein laminin α4 (lama4) in adipocyte...
Show moreThe overall goal of this work is to apply in vivo and in vitro models to study the basement membrane protein laminin α4 (lama4) in adipocyte function. Adipose tissue accumulation, lipogenesis, and structure were examined in mice with a null mutation of the lama4 gene (Lama4−/−) and compared to wild-type animals (Lama4+/+). The Lama4−/−mice phenotype was investigated to evaluate if the differences were due specifically to the adipose tissue function. Physical activity and food intake does not differ between Lama4+/+ and Lama4−/− mice. However, Lama4−/− mice have a significantly increased metabolic rate at 25°C and 16°C compared to Lama4+/+ mice. In contrast, in thermoneutral conditions at 30°C both Lama4+/+ and Lama4−/− mice exhibit equivalent metabolic rates. Interestingly, when room temperature housed mice fat pads were evaluated with immunohistochemistry, Lama4−/− mice exhibit significantly increased UCP-1 expression in subcutaneous adipose. These results suggest that beiging, white to brown adipocytes, in subcutaneous adipose tissue in Lama4−/− mice may lead to decreased adipose tissue accumulation and improved metabolic function. While animal models indicate the absence of lama4 results in more beiging in subcutaneous adipose tissue, an in vitro tissue engineered model was developed to study the adipocyte function in a controlled microenvironment. Primary cell spheroids developed from Lama4+/+ and Lama4−/− were incorporated into synthetic poly(ethylene glycol) (PEG) hydrogels within a range of stiffnesses. When the cells were given the same chemical cues their functions differed depending upon microenvironment stiffness. Beige function in adipocyte cells in 3D can be influenced by matrix stiffness. In conclusion, the laminin alpha 4 basement membrane protein absence in adipose tissue results in adipocyte functional changes in vivo. The Lama4−/− mice have resistance to diet induced weight gain and increased metabolic rate at room temperature and when cold challenged. The Lama4−/− mice had increased beiging in the subcutaneous depot. Additionally, a tissue engineered model was developed to further study cell-ECM interactions first identified in an animal model. These in vivo findings and the engineered model of adipose tissue have great potential for studying obesity and other adipose related diseases. Future work will require continued interdisciplinary collaboration towards the successful identification and screening of novel therapeutics using engineered tissue models.
Ph.D. in Biomedical Engineering, July 2015
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