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Title: STUDIES ON SYNTHETIC APPLICATIONS OF STEREOSELECTIVE AND REGIOSELECTIVE RING OPENING REACTIONS OF AZIRIDINIUM IONS
Creator: Chen, Yunwei
Date: 2014, 2014-12
Description: Aziridinium ions are valuable reactive intermediates in organic synthesis. Regioselective and stereoselective ring opening reactions of...
Show moreAziridinium ions are valuable reactive intermediates in organic synthesis. Regioselective and stereoselective ring opening reactions of aziridinium ions can provide various useful building blocks including optically active vincinal amines, amino alcohols and amino esters. Aziridinium ions are also involved in the biological process of anti-cancer agents. However, aziridinium ions are under-utilized in organic synthesis. In this thesis, we utilize stereoselective and regioselective ring opening reactions of aziridinium ions for synthesis of enantiomerically enriched compounds. Ring opening reactions of aziridinium ions were utilized in intramolecular Friedel-Crafts (FC) reactions for stereoselective and regioselective synthesis of 4-substituted tetrahydroisoquinoline. A series of β-haloamine were prepared as precuresors of aziridinium ions. The reaction conditions for ring opening of aziridinium ions for the FC reactions including temperature, catalysts, and solvents were optimized. Further, the reaction mechanism was studied to prove that the aziridinium ions were formed as the key intermediates during the intramolecular FC reaction. Intermolecular nucleophilic ring opening reaction of aziridinium ions was studied as a convenient method of carbon-carbon formation. Regioselective and stereoselective nucleophilic substitution reactions of aziridinium ions with indole analogues were carried out for the synthesis of optically active tryptamine analogues. The reactions proceeded smoothly to provide the tryptamine analogues in high yield in the presence of halo-sequestering agents, while the reaction provided the tryptamine products in significantly low yield in the absence of halo-sequestering agents. Ring opening reactions of aziridinium ions with malonic esters and Grignard reagents were carried out for the respective synthesis of optically active tryptamine analogues, γ-aminobuyric acid (GABA), and α-amine derivatives. The regiospecific ring opening reactions of aziridinium ions was directly applied for the synthesis of bifunctional ligands which have a potential use in targeted therapy and imaging of cancers. The novel bifunctional chelates with a shorter alkyl spacer C-NETA and 2E-C-NETA as well as the chelates with a longer alkyl spacer 5p-C-NETA were prepared. 5p-C-NETA was conjugated to a cyclic peptide c(RGDyK) as a targeting moiety for use in targeted radiation therapy. In addition, 2E-C-NETA was conjugated to a fluorescent dye Cy5.5 for theranostic applications. The experimental results indicated that the new bifunctional ligands have promising applications in the biomedical field. In summary, stereoselective and regioselective ring opening reactions of aziridinium ions have been successfully applied for the synthesis of optically active compounds such as 4-substituted tetrahydroisoquinolines, tryptamines, γ-aminobuyric acid, α-amine derivatives and the bifunctional chelators. We demonstrated that ring opening of versatile aziridinium intermediates is a strightforward and convenient method for the synthesis of various optically active compounds.
Ph.D. in Chemistry, December 2014
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Title: Test of slender wooden struts for aeroplanes
Creator: Smith, M. A,, Kellener, W. A., Stevens, W. A.
Date: 2009, 1910
Publisher: Armour Institute of Technology
Description: http://www.archive.org/details/testofslenderwoo00smit
Thesis (B.S.)--Armour Institute of Technology

Title: Inclusive measurements at HERA from low to high x, Proceedings of the XLIII International Symposium on Multiparticle Dynamics
Creator: Behnke, Olaf
Date: 2013-09-15, 2013-09-15
Publisher: IIT Press
Description: New inclusive Deep Inelastic Scattering (DIS) measurements are presented, obtained with the H1 and ZEUS detectors at HERA. The results...
Show moreNew inclusive Deep Inelastic Scattering (DIS) measurements are presented, obtained with the H1 and ZEUS detectors at HERA. The results comprise (flavour) inclusive DIS cross sections as well as inclusive charm production. In the area of inclusive DIS, both H1 and ZEUS completed last year their high Q2 Neutral and Charged current measurements exploiting the large statistics from the HERA II running period. For inclusive charm production, H1 and ZEUS published a combination of numerous existing measurements based on various tagging methods. Among other things a precise determination of the running charm quark mass mc(mc) was obtained from the combined data.
Sponsorship: IIT College of Science, High Energy Physics Division of Argonne National Laboratory
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Title: Hierarchical Structured Data Organization System
Creator: Frieder, Ophir, Kapoor, Sanjiv
Date: 2015-09-09, 2015-09-08
Description: A method in a data processing system and apparatus for organizing files or web pages, structured or unstructured, of multiple users stored...
Show moreA method in a data processing system and apparatus for organizing files or web pages, structured or unstructured, of multiple users stored across one or more server computers into hierarchical file structures on a recordable medium of a data processing system. A user-defined metalabel is assigned to each of the electronic files or web pages. The electronic files or web pages are organized as a function of the metalabels into the hierarchical file structures.
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: A CONCEPTUAL SOLAR CHIMNEY PLANT AND FLORAL FARM USING ETFE AND BAMBOO
Creator: De Vita, Niels
Date: 2012-11-20, 2012-12
Description: Motivated by a desire to create an architectural response to the environmental and social challenges of today, the following thesis project...
Show moreMotivated by a desire to create an architectural response to the environmental and social challenges of today, the following thesis project attempts to offer new paths for the future development of the solar chimney energy plant concept originally developed by the German engineer Jӧrg Schlaich in the early 1980s. The starting point of this thesis was to analyze the solar chimney prototype completed in the Manzanares desert in 1982 in order to understand the parameters guiding the design. The analysis allowed me to better understand the potential of the concept and to recognize the opportunity that existed to push the technological boundaries to craft a new design that reflects the current socio-political, economical and environmental context we live in. In the following pages, I attempt to demonstrate that the concept could be made even more appealing through the use of technology and locally available resources. By doing this, I seek to reinvigorate the idea, opening paths for a new conversation about the potential of the project as a social agent for progress. Throughout this thesis, I remain respectful and aware of the accomplishments of the pioneers before me, simply taking cues from their work to suggest new alternatives and solutions to a problem that has been made even more pressing due to the world’s energy crisis and economic uncertainty.
M.S. in Architecture, December 2012
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Title: Constant Speed Drive for Magnetic Recorders
Creator: Camras, Marvin
Date: 1945-04-03
Description: Sponsorship: Armour Research Foundation
United States Patent

Title: THE CHANGE OF KURTOSIS IN IMPORTANCE SAMPLING FOR MONTE CARLO
Creator: Zhang, Xiaodong
Date: 2013, 2013-12
Description: The Mont e Carlo (II IC) Method is commonly used to approximat e mult ivariat e integrals, which can be interpreted as means of random variab...
Show moreThe Mont e Carlo (II IC) Method is commonly used to approximat e mult ivariat e integrals, which can be interpreted as means of random variab les. The IIIC method uses th e sample mean to estimate the tr ue mean. In this thesis, we focus on minimizing th e sample size in MC simulat ion needed to sat isfy the specified error tolerance. Based on t he algorithm proposed by [5], we explain that t he cost of reliable IIIe est imat ion depends not only on variance but also on kurtosis. T herefore, when we try to improve th e efficiency of MC simulation by reducing variance, such as with Importance Sampling (IS), we need also look into the change of kurtosis. We analyze the change of cost in terms of the change of kur tosis and the change of variance. For a special case of IS we explore how to find th e optimal density in order to reduce variance.
M.S. in Applied Mathematics, December 2013
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Title: Wellness and Education
Creator: Mason, Laurie
Date: 2012, 2012-05
Description: What if the school were more like a playground; a laboratory for exploration and discovery? What if the place itself actually inspired the...
Show moreWhat if the school were more like a playground; a laboratory for exploration and discovery? What if the place itself actually inspired the students within it? My proposal for a new primary school in Chicago attempts to become such a place. With an emphasis on wellness and ecologically based practices the school becomes a teaching tool. Featuring a diverse range of flexible interior and exterior spaces, the building supports different learning environments. The school also encourages community involvement through shared resources and volunteer opportunities. The project becomes more than a school; an integral part of the neighborhood and place to experience learning.
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Title: Method and Apparatus for Detecting Collisions on and Controlling Access to a Communications Channel
Creator: Campbell, Graham M., Wu, Chien-ting
Date: 2009-05-14, 2002-06-18
Description: A nodal apparatus for sending and receiving digital data in multiple data slots has a transmitter for transmitting a request for multiple data...
Show moreA nodal apparatus for sending and receiving digital data in multiple data slots has a transmitter for transmitting a request for multiple data slots during a control minislot. A conflict resolution queue representative of nodal apparatus sending substantially simultaneous requests for transmission resulting in a collision in a minislot is maintained and stored in a memory. A transmission queue representative of nodal apparatus that have successfully transmitted in a minislot and can be queued for data slot transmission is stored in memory. The transmitter sends multiple data slots signals comprising multiple slots of digital data in response to the transmission queue. A receiver receives multiple data slots signals comprising digital data. A high priority transmission queue may also be stored in memory.
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: Juvenile Treatment Center
Creator: Cueva, Hernan
Date: 2010-07-29

Title: Safety Timing Mechanism for Magnetic Recorders
Creator: Camras, Marvin
Date: 1945-08-07
Description: Sponsorship: Armour Research Foundation
United States Patent

Title: ELIASHBERG ANALYSIS OF CUPRATE OXIDE SUPERCONDUCTORS
Creator: Ahmadi, Omid
Date: 2011-11, 2011-12
Description: In this thesis, evidence for antiferromagnetic spin uctuations as the pairing glue in high temperature superconductors is presented through a...
Show moreIn this thesis, evidence for antiferromagnetic spin uctuations as the pairing glue in high temperature superconductors is presented through a modi ed Eliashberg analysis of experimental tunneling data of Bi2212 over a wide range of doping. In particular, the normalized conductance data of the junctions, from optimal to overdoped, will be tted at T=0K using d-wave Eliashberg equations where the spectral function is modeled after spin uctuation spectra seen in experiments. The corresponding real and imaginary diagonal and anomalous self-energy curves are extracted and compare well to photoemission experiments. This is followed by a temperature dependent Eliashberg analysis where the spectral function is now temperature dependent, based on trends seen in inelastic neutron scattering experiments. New results for temperature dependent self energy curves are also compared to experiment with slight deviations. Finally, the Josephson product is calculated as an independent check of the tunneling matrix used in tting the data.
Ph.D. in Physics, December 2011
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Title: Reel Lock
Creator: Camras, Marvin, Galus, Stanley A.
Date: 4/23/2009, 1966-10-11
Description: Sponsorship: IIT Research Institute
United States Patent

Title: Hafnium Base Alloy (CR-Al)
Creator: Hill, Vernon L., Nichols, Harry R.
Date: 2009-04-27, 1971-07-27
Description: Sponsorship: IIT Research Institute
United States Patent

Title: Investigation of Fresh Produce Washing on E. Coli O157:H7 and Murine Norovirus with Peroxyacetic Acid and High Power Ultrasound
Creator: Yuan, Wen
Date: 2011-12-05, 2011-12
Description: E. coli O157:H7 and norovirus have each been responsible for outbreaks of foodborne illness involving fresh leafy green vegetables....
Show moreE. coli O157:H7 and norovirus have each been responsible for outbreaks of foodborne illness involving fresh leafy green vegetables. Peroxyacetic acid (POAA) has the potential to be an effective sanitizer during commercial fresh-cut produce washing. The addition of high power ultrasound (HPU) to the washing system may enhance the POAA efficacy. The purpose of this study was to reduce E. coli O157:H7 and norovirus contamination during commercial fresh-cut lettuce washing using POAA and HPU. Fresh-cut romaine lettuce leaves were inoculated with E. coli O157:H7 or murine norovirus (MNV, a surrogate for the human norovirus) and washed by POAA and HPU. Cross-contamination was tested by washing clean leaves in contaminated processing water where pre-inoculated leaves were washed previously. A high level of cross-contamination (4.5-log CFU/g E. coli) occurred after uninoculated leaves were rinsed in contaminated wash water for 2 min. A subsequent 2 min wash in POAA alone or in combination with HPU reduced counts by approximately 1.2-log and 2.3-log, respectively. More than 2-log norovirus was removed from washing 2 min in either DI water or POAA. However infectious MNV washed from leaves was not detected in wash water containing POAA. Those results implied a high possibility of cross-contamination during freshproduce washing, and indicate that adding POAA and HPU in addition to washing water in wash water can reduce cross-contamination rate.
M.S. in Food Safety and Technology, December 2011
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Title: Video Recording System and Method
Creator: Camras, Marvin
Date: 2009-04-27, 1971-06-28
Description: Sponsorship: IIT Research Institute
United States Patent

Title: Highrise
Creator: Ma, Shasha
Date: 5/4/2011, 2011-05
Description: Highrise structure study
Sponsorship: Land, Peter

Title: Agricultural Rehabilitation Tower: RGG-JYL Final Boards 050111
Creator: Garcia, Rodrigo, Lee, Jennifer
Date: 5/4/2011, 2011-05
Description: to create a vertical community bound together by two key issues/requirements in Korean society: urban agriculture and mental health care to...
Show moreto create a vertical community bound together by two key issues/requirements in Korean society: urban agriculture and mental health care to create a ‘vertical façade farm’ capable of producing 156 tons of vegetables (predominantly lettuce, tomatoes, peppers, and strawberries) and 200 tons of fish per year to create a mental health sanctuary (or sanatorium) that provides short term (days), midterm (months) and long term (years) residence and care for people with mental health issues that may require physical operations and/or psychological care. to actively engage the mental health residents in aspects of the agricultural production to draw on research showing that engagement with plants/nature assists in mental healing. to create a large multi-purpose space at the ground floor of the building which will largely serve as a farmer’s market for sale of the agricultural produce and engagement between the community residents and the public to create a series of gardens/green spaces at height within the complex, as well as vertical green walls, for healing (residents and urban issues) to use the double-skin ‘façade farm’ for assisting in passive natural ventilation of internal spaces
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Title: DEVELOPMENT OF A NEW EMERGENCY EVACUATION SYSTEM FOR MINES
Creator: Qian, Qingyi
Date: 2011-08, 2011-07
Description: Underground mining is a very high risk industry. There are many potential hazards in the underground mining these include fire, explosion,...
Show moreUnderground mining is a very high risk industry. There are many potential hazards in the underground mining these include fire, explosion, inundation, roof collapse, toxic gases, chemical pollution, etc. Over past centuries, in US alone, more than 100,000 miners lost their life in different accidents. The primary safety methods used in underground mines concentrate on the monitoring of the hazardous gases, fire detection and ventilation. Using advanced instruments and monitoring techniques have significantly reduced the accidents in the modern mines. However despite the advancement of these monitoring facilities, accidents still occur in underground mining annually around the world, and many miners were killed because they were trapped and unable to escape due to blocked of exit access. This thesis describes a new development of an emergency evacuation system in underground mines and analyzes the advantages and disadvantages of the system. It is expected that the new system will greatly improve the emergency exit methods and save more lives in the future. The new emergency evacuation system consists of vertical concrete mineshaft, high capacity mineshaft elevators, surface terminal and underground support structures. In addition, the study of numerical simulation was carried out to observe the ground response during excavation. A typical ground profiles for underground mining in south part of China was used in this analysis. The results selected from shaft excavation simulation indicate that fluid drilling method effectively prevents the soil around mineshaft from collapse hazard. Compared to soil strength, soil stiffness has a significant influence on the soil response induced by excavating shafts.
Ph.D. in Civil Engineering, July 2011
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Title: Tension Indicating Fastener
Creator: Liber, Theodore
Date: 2009-04-30, 1973-02-27
Description: A bolt having a shank and integral head has a strip of photoelastic material mounted in the head for manifesting in the form of photoelastic...
Show moreA bolt having a shank and integral head has a strip of photoelastic material mounted in the head for manifesting in the form of photoelastic fringes linearly related to bolt tension the bending stresses created in the head during loading of the bolt. To determine the tension in the bolt during or after loading, polarized light is directed toward the photoelastic strip and reflected light from the strip is analyzed to measure fringe order. The fringe order is related to the amount of bending stresses in the head of the bolt by a predetermined calibration curve, the bending stresses being linearly related to bolt tension.
Sponsorship: IIT Research Institute
United States Patent
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