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Pages
- Title
- An Introduction to the Societal Roles of Ethics Codes
- Creator
- Laas, Kelly, Davis, Michael, Hildt, Elisabeth
- Date
- 2022, 2022-01-03
- Publisher
- Springer, Cham
- Description
-
In this collected volume, we are interested in the roles of ethics codes and ethical guidelines in professions in which research and...
Show moreIn this collected volume, we are interested in the roles of ethics codes and ethical guidelines in professions in which research and innovation play an important role and where emerging technologies bring about considerable, sometimes fast-paced change.
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- Codes of Ethics and Ethical Guidelines: Emerging Technologies and Changing Fields
- Title
- Informed Consent in Digital Data Management
- Creator
- Hildt, Elisabeth, Laas, Kelly
- Date
- 2022, 2022-01-03
- Publisher
- Springer, Cham
- Description
-
This article discusses the role of informed consent, a well-known concept and standard established in the field of medicine, in ethics codes...
Show moreThis article discusses the role of informed consent, a well-known concept and standard established in the field of medicine, in ethics codes relating to digital data management. It analyzes the significance allotted to informed consent and informed consent-related principles in ethics codes, policies, and guidelines by presenting the results of a study focused on 31 ethics codes, policies, and guidelines held as part of the Ethics Codes Collection. The analysis reveals that up to now, there is a limited number of codes of ethics, policies, and guidelines on digital data management. Informed consent often is a central component in these codes and guidelines. While there undoubtedly are significant similarities between informed consent in medicine and digital data management, in ethics codes and guidelines, informed consent-related standards in some fields such as marketing are weaker and less strict. The article concludes that informed consent is an essential standard in digital data management that can help effectively shape future practices in the field. However, a more detailed reflection on the specific content and role of informed consent and informed consent-related standards in the various areas of digital data management is needed to avoid the weakening and dilution of standards in contexts where there are no clear legal regulations.
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- Codes of Ethics and Ethical Guidelines: Emerging Technologies and Changing Fields
- Title
- Mary Henry painting an interior mural at Hewlett-Packard, Palo Alto, California, ca. 1958
- Date
- 1958
- Description
-
Photograph of Mary Henry painting an interior mural at Hewlett-Packard in Palo, Alto, California. Photographer unknown. Inscription on verso: ...
Show morePhotograph of Mary Henry painting an interior mural at Hewlett-Packard in Palo, Alto, California. Photographer unknown. Inscription on verso: "Mary Henry 2222 East White Fir Place Freeland, WA 98249 206-331-3404 / The artist shown working on the Hewlett-Packard murals. The plant is built in the Stanford Industrial Park, Palo Alto, California, 1958."
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- Mary Dill Henry Papers, 1913-2021
- Title
- Untitled manuscript
- Creator
- Henry, Mary Dill, 1913-2009
- Date
- 1973-12-04
- Description
-
Handwritten document by Mary Dill Henry describing her motivations, inspirations, and aspirations for painting.
- Collection
- Mary Dill Henry Papers, 1913-2021
- Title
- Letter from Frank T. Walsh to Mary Henry, May 27, 1966
- Creator
- Walsh, Frank T.
- Date
- 1966-05-27
- Description
-
Typescript letter with signature from Frank T. Walsh, Director of Corporate Industrial Design at the Ampex Corporation, to Mary Henry. The...
Show moreTypescript letter with signature from Frank T. Walsh, Director of Corporate Industrial Design at the Ampex Corporation, to Mary Henry. The letter was composed in response to the promotional material Henry provided Ampex in advance of her first solo exhibition, which opened in 1967 at the Ampex Corporation in Redwood City, California.
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- Mary Dill Henry Papers, 1913-2021
- Title
- Mary Henry at the opening of a solo exhibition at the Whatcom Museum, Bellingham, Washington, 1988
- Date
- 1988
- Description
-
Photograph of Mary Dill Henry taken at the opening of a solo exhibition at the Whatcom Museum, Bellingham, Washington, 1988. Inscription on...
Show morePhotograph of Mary Dill Henry taken at the opening of a solo exhibition at the Whatcom Museum, Bellingham, Washington, 1988. Inscription on verso: "Mary Henry / Whatcom Museum, Bellingham, Wa / At the opening of her show." Photographer unknown.
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- Mary Dill Henry Papers, 1913-2021
- Title
- Photograph of Mary Henry in front of one of her paintings, ca. 1966-67
- Date
- 1966-1967
- Description
-
Photograph of Mary Dill Henry in front of one of her paintings (title unknown), ca. 1966-1967. Verso of photograph contains a stamp with...
Show morePhotograph of Mary Dill Henry in front of one of her paintings (title unknown), ca. 1966-1967. Verso of photograph contains a stamp with contact information for Art to Industry, a business that attempted to connect artists with corporate patrons: "ART TO INDUSTRY / ESTELLE GRUNEWALD / 4261 RUTHELMA PALO ALTO CALIF 94308 / PHONE 325-4167." Photographer unknown. Date of photograph is unknown. Date range listed is approximate.
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- Mary Dill Henry Papers, 1913-2021
- Title
- A Statement
- Creator
- Henry, Mary Dill, 1913-2009
- Date
- 1988-01
- Description
-
Typescript artist statement written by Mary Dill Henry in January, 1988. A Statement describes Henry's means of conceiving her geometric...
Show moreTypescript artist statement written by Mary Dill Henry in January, 1988. A Statement describes Henry's means of conceiving her geometric paintings and her thoughts on their size and impact.
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- Mary Dill Henry Papers, 1913-2021
- Title
- Contact print containing photographs of Mary Henry, ca. 1966-1967
- Date
- 1966-1967
- Description
-
Contact sheet of photographs of Mary Henry and her paintings, with some photographs including Estelle Grunewald, artist and founder of Art to...
Show moreContact sheet of photographs of Mary Henry and her paintings, with some photographs including Estelle Grunewald, artist and founder of Art to Industry, a business that attempted to connect artists with corporate patrons. The photographs are likely from Henry's solo exhibition in 1967 at the Ampex Corporation in Redwood City, California. Verso of photograph contains a stamp with contact information for Art to Industry: "ART TO INDUSTRY / ESTELLE GRUNEWALD / 4261 RUTHELMA PALO ALTO CALIF 94308 / PHONE 325-4167." Photographer unknown. Date of photographs is unknown. Date range listed is approximate.
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- Mary Dill Henry Papers, 1913-2021
- Title
- Mary Henry and her painting Giverny 2 at the opening of a solo exhibition at the Whatcom Museum, Bellingham, Washington, 1988
- Date
- 1988
- Description
-
Photograph of Mary Dill Henry and her painting Giverny 2, taken at the opening of a solo exhibition at the Whatcom Museum, Bellingham,...
Show morePhotograph of Mary Dill Henry and her painting Giverny 2, taken at the opening of a solo exhibition at the Whatcom Museum, Bellingham, Washington, 1988. Inscription on verso: "Mary Henry - Opening at the Whatcom Museum shown with Giverny #2 painting." Photographer unknown.
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- Mary Dill Henry Papers, 1913-2021
- Title
- Mary Henry, date unknown
- Description
-
Photograph of Mary Henry. Photographer unknown. Date of photograph is unknown
- Collection
- Mary Dill Henry Papers, 1913-2021
- Title
- Mary Henry and Estelle Grunewald in front of one of Henry's paintings, ca. 1966-1967
- Date
- 1966-1967
- Description
-
Photograph of Mary Henry in front of one of her paintings with Estelle Grunewald, artist and founder of Art to Industry, a business that...
Show morePhotograph of Mary Henry in front of one of her paintings with Estelle Grunewald, artist and founder of Art to Industry, a business that attempted to connect artists with corporate patrons, likely from Henry's solo exhibition in 1967 at the Ampex Corporation in Redwood City, California. Photographer unknown. Date of photograph is unknown. Date range listed is approximate. Inscription on verso, in addition to stamp, reads: "Please return to ART TO INDUSTRY / ESTELLE GRUNEWALD / 4261 RUTHELMA PALO ALTO CALIF 94308 / PHONE 325-4167 / 60 x 60 Square - black + white / Estelle Grunewald, Director, Art-to-Industry / Mary Henry, Artist." A stamp from the Ampex Corporation's Photographic Department, including the identifier X261-12, is also found on the verso.
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- Mary Dill Henry Papers, 1913-2021
- Title
- The Cycle, 1935
- Creator
- Armour Institute of Technology
- Date
- 1935
- Description
-
Volume 23 of The Cycle, the 1935 yearbook for the Armour Institute of Technology. The Armour Institute of Technology yearbooks was known by...
Show moreVolume 23 of The Cycle, the 1935 yearbook for the Armour Institute of Technology. The Armour Institute of Technology yearbooks was known by three different titles: Integral (1898-1910), Senior Class Book (1911-1912), and The Cycle (1913-1940). A 1902 volume of Integral is not a part of Galvin Library collections; it is uncertain of a yearbook was published that year. Publication of the Armour Institute ceased in 1941, when the Armour Institute of Technology merged with the Lewis Institute to form Illinois Institute of Technology.
Sponsorship: Scanning of the Armour Institute of Technology yearbooks was supported in part by an award from the Illinois State Historical Records Advisory Board, through funding from the National Historical Publications and Records Commission, National Archives and Records Administration.
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- Armour Institute of Technology yearbooks, 1898-1940
- Title
- Simulation and Experimental Testing of High-Gradient Dielectric Disk Accelerating Cavities
- Creator
- Weatherly, Sarah K.
- Date
- 2022
- Description
-
Structure-based wakefield acceleration can be accomplished using either Collinear Wakefield Acceleration (CWA) where the drive beam and the...
Show moreStructure-based wakefield acceleration can be accomplished using either Collinear Wakefield Acceleration (CWA) where the drive beam and the witness beam are located on the same beamline or Two Beam Acceleration (TBA) where the RF power generated by the drive beam is extracted and transferred to the witness beam line. A Dielectric Disk Accelerator (DDA) is an accelerating structure that is utilized by TBA that uses dielectric disks to improve the structure's shunt impedance and accelerate the witness beam. Dielectric based accelerators studied in this thesis are X-Band structures (have a working frequency between 8 and 12 GHz) that can use any pulse length but in this study utilize short (<20 ns) traveling wave pulses. Short pulse lengths are used to decrease breakdown probability and allow for a large gradient. DDAs have a higher group velocity and a larger shunt impedance compared to traditional metallic accelerating structures while maintaining a large accelerating gradient. DDAs are a strong candidate for use in the Argonne Wakefield Accelerator’s 500 MeV Demonstrator. Recent experimental results of a clamped single cell structure demonstrated a >100 MV/m accelerating gradient with no evidence of breakdown in the RF volume. Additional structures, including a brazed single cell model and a multicell structure, have been designed and are now being fabricated for high power testing.
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- Title
- A SCALABLE AND CUSTOMIZABLE SIMULATION PLATFORM FOR ACCURATE QUANTUM NETWORK DESIGN AND EVALUATION
- Creator
- Wu, Xiaoliang
- Date
- 2021
- Description
-
Recent advances in quantum information science enabled the development of quantum communication network prototypes and created an opportunity...
Show moreRecent advances in quantum information science enabled the development of quantum communication network prototypes and created an opportunity to study full-stack quantum network architectures. The scale and complexity of quantum networks require cost-efficient means for testing and evaluation. Simulators allow for testing hardware, protocols, and applications cost-effectively before constructing experimental networks. This work develops SeQUeNCe, a comprehensive, customizable quantum network simulator. We have explored SeQUeNCe for quantum communication network evaluation. We use SeQUeNCe to study the performance of the quantum network with different hardware and applications. Additionally, we extend SeQUeNCe to a parallel discrete-event simulator by using the message passing interface (MPI). We comprehensively analyze the benefit and overhead of parallelization. The parallelization technique significantly increases the scalability of SeQUeNCe. In the future, we would like to improve SeQUeNCe in three aspects. First, we plan to continue reducing overhead from parallelization and increasing the scalability of SeQUeNCe. Second, we plan to investigate means to model quantum memory, entanglement protocols, and control protocols to enrich simulation models in the SeQUeNCe library. Third, we plan to integrate hardware with SeQUeNCe to enable high-fidelity analysis.
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- Title
- Development of MIITRA T1w, DTI and FOD templates of the older adult brain in a common space
- Creator
- Wu, Yingjuan
- Date
- 2022
- Description
-
Human brain atlases play an important role in neuroimaging studies and are commonly used as references for spatial normalization, tissue...
Show moreHuman brain atlases play an important role in neuroimaging studies and are commonly used as references for spatial normalization, tissue segmentation, automated brain parcellation, seed selection for functional connectivity analyses and fiber-tracking, or standards for algorithm evaluation. A brain atlas typically consists of brain templates of different imaging modalities in a common space and semantic labels that delineate brain regions according to the characteristics of the underlying tissue.High-quality T1-weighted (T1w) and diffusion tensor imaging (DTI) brain templates that are representative of the individuals under study enhance the accuracy of template-based neuroimaging investigations, and when they are also located in a common space they facilitate optimal integration of information on brain morphometry and diffusion characteristics. However, such multimodal templates have not been constructed for the brain of older adults. This thesis introduced an iterative method for construction of multimodal T1w and DTI templates that aims at maximizing the quality of each template separately as well as the spatial matching between templates. The performance of the proposed method was evaluated across iterations and was compared to the performance of state-of-the-art multimodal template construction approaches based on multichannel registration. Using the proposed method, along with other recently developed techniques, high-quality T1w and DTI templates of the older adult brain were developed in a common space at 0.5mm resolution for the MIITRA atlas. In this thesis, the new templates were compared to other available templates in terms of the image quality, inter-subject and inter-modality spatial normalization accuracy achieved when used as a reference, and the representativeness of the older adult brain. Furthermore, as fiber orientation distribution (FOD) model is capable of resolving intravoxel heterogeneity, which overcomes the limitations of the DTI model especially in regions with complex neuronal microarchitecture, FOD template is in high demand to facilitate FOD-based, fixel-based analyses, white matter connectivity studies and white matter parcellations. In this thesis, several FOD template construction methods were compared and a FOD template was developed at 0.5mm resolution for the MIITRA atlas. Overall, the present work brought new insights into multimodal template construction, conducted a thorough, quantitative evaluation of available multimodal template construction methods, and generated much-needed high quality T1w, DTI and FOD templates of the older adult brain in a common space with 0.5mm resolution.
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- Title
- AN EXPLORATION INTO THE EFFECTS OF CHROMATIN STRUCTURAL PROTEINS ON THE DYNAMICS AND ENERGETIC LANDSCAPE OF NUCLEOSOME ARCHITECTURES
- Creator
- Woods, Dustin C
- Date
- 2022
- Description
-
Comprised of eight core histones wrapped around at least 147 base pairs of DNA, nucleosomes are the fundamental unit the chromatin fiber from...
Show moreComprised of eight core histones wrapped around at least 147 base pairs of DNA, nucleosomes are the fundamental unit the chromatin fiber from which long arrays are built to compact genetic information into the cell nucleus. Structural proteins, such as linker histones (LH) and centromere proteins (CENP), interact with the DNA to dictate the exact architecture of the fiber which can directly influence the regulation of epigentic processes. However, the mechanisms by which structural proteins affect these processes are poorly understood. In this thesis, I will explore the various way in which LHs and CENP-N affect nucleosome and, by extension, chromatin fiber dynamics. First, I present a series of simulations of nucleosomes bound to LHs, otherwise known as chromatosomes, with the globular domain of two LH variants, generic H1 (genGH1) and H1.0 (GH1.0), to determine how their differences influence chromatosome structures, energetics and dynamics. These simulations highlight the thermodynamic basis for different LH binding motifs, and details their physical and chemical effects on chromatosomes. Second, I examine how well the findings above translate from mono-nucleosomes to poly-nucleosome arrays. I present a series of molecular dynamics simulations of octa-nucleosome arrays, based on a cryo-EMstructure of the 30-nm chromatin fiber, with and without the globular domains of the H1 LH to determine how they influence fiber structures and dynamics. These simulations highlight the effects of LH binding on the internal dynamics and global structure of poly- nucleosome arrays, while providing physical insight into a mechanism of chromatin compaction. Third, I took a brief departure from LHs to study the effects that the centromere protein N (CENP-N) has on the poly-nucleosome systems. I present a series of molecular dynamics simulations of CENP-N and di-nucleosome complexes based on cryo- EM and crystal structures provided by Keda Zhou and Karolin Luger. Simulations were conducted with nucleosomes in complex with one, two, and no CENP-Ns. This work, in collaboration with the Karolin Luger Group (University of Colorado – Boulder) and the Aaron Straight Group (Stanford University), represents the first atomistic simulations of this novel complex, providing the foundation for a plethora of future research opportunities exploring centromeric chromatin the effect that its structure and dynamics have on epigenetics. Lastly, I return to the chromatosome to study how DNA sequence affects the free energy surface and detailed mechanism of LH transitions between binding modes. I used umbrella sampling simulations to produce PMFs of chromatosomes wrapped in three different DNA sequences: Widom 601, poly-AT, and poly-CG. This work, my final in the series, represents a culmination of my studies furthering the understanding of biophysical phenomena surrounding LHs and how they can be extrapolated towards epigentic mechanisms. I was able to report on the first PMFs illustrating a previously unknown transition and describe the transition mechanism as it depends on DNA sequence.
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- Title
- The Studio Practice for Sustainable (Craft) Production
- Creator
- Werdhaningsih, Hendriana
- Date
- 2022
- Description
-
Craft market demand globally is rising. On the other hand, the domination of economic goals in craft production is threading the social system...
Show moreCraft market demand globally is rising. On the other hand, the domination of economic goals in craft production is threading the social system and the environment. Craft production facts do not represent the sustainable development principles that should be a central concept for this age. Design as practice and method had not yet correctly facilitated craft production to embrace the harmony of the social, environmental, and economic systems. Believing that studio is a core design practice, this research investigated studio practice through interviews, field research, and action research conducted in Indonesia and the US. It developed a model called Studio Practice for Sustainable (Craft) Production, the SP2 Model. The Model helps designers, the crafts community, and stakeholders ensure their role in the studio practice and determine their goals for sustainable development. The SP2 Model offers alternative practical solutions in craft production, contributes to polycentric discourse, and designs interventions in sustainable development models.
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- Title
- ESTIMATING PM2.5 INFILTRATION FACTORS FROM REAL-TIME OPTICAL PARTICLE COUNTERS DEPLOYED IN CHICAGO HOMES BEFORE AND AFTER MECHANICAL VENTILATION RETROFITS
- Creator
- Wang, Mingyu
- Date
- 2021
- Description
-
PM2.5 are fine inhalable particles that are 2.5 micrometers or smaller in size. Indoor PM2.5 consists of outdoor PM2.5 (ambient PM2.5) that is...
Show morePM2.5 are fine inhalable particles that are 2.5 micrometers or smaller in size. Indoor PM2.5 consists of outdoor PM2.5 (ambient PM2.5) that is infiltrated into the indoor environment and indoor generated PM2.5 (non-ambient PM2.5). As people spend nearly 90% of their lifetimes indoors, with most of that time in their homes, PM2.5 exposure in homes results in severe health effects such as asthma. One strategy increasingly being used to dilute air pollutants generated indoors and improve indoor air quality (IAQ) in homes is the introduction of mechanical ventilation systems. However, mechanical ventilation systems also have the potential to introduce more ambient PM2.5 than relying on infiltration alone, although limited data exist to demonstrate the magnitude of impacts in occupied homes. The objective of this paper is to estimate the infiltration factor (Finf) of PM2.5 before and after installing mechanical ventilation systems in a subset of occupied homes. The data source utilized comes from the Breathe Easy Project, a more than 2-year-long study conducted in 40 existing homes in Chicago, IL aiming to explore the effects of three different types of mechanical ventilation system retrofits on IAQ and asthma. An automated algorithm was developed to remove indoor PM2.5 peaks in time-series data collected from optical particle counters deployed inside and outside of each home. The Finf was estimated using the resulting indoor/outdoor ratio with indoor peaks removed. Before mechanical ventilation retrofits, the weekly median Finf was 0.29 (summer median = 0.41, fall median = 0.26, winter median = 0.29, spring median = 0.30); after mechanical ventilation retrofits, the median Finf was 0.34 (winter median= 0.28, spring median = 0.45, summer median = 0.54, fall median = 0.20). Differences in Finf between pre- and post-intervention periods were not statistically significant (p = 0.23 from Wilcoxon signed rank tests). The median PM2.5 infiltration factor increased ~22% (from 0.27 to 0.33) with the installation of balanced ventilation systems with energy recovery ventilators (ERV), although differences were not statistically significant (Wilcoxon signed rank p = 0.35). The median PM2.5 infiltration factor decreased ~4% (from 0.28 to 0.27) after installing intermittent CFIS systems, which intermittently supply ventilation air through the existing central air handling units and associated filters (which were upgraded to a minimum of MERV 10 in all CFIS homes), although differences were not statistically significant (Wilcoxon signed rank p = 0.24). The median PM2.5 infiltration factor increased ~26% (from 0.35 to 0.44) with the installation of continuous exhaust-only systems, and differences were significant (Wilcoxon signed rank p = 0.04). These results suggest that the filtration mechanisms used on the CFIS and balanced systems were adequate for maintaining similar distributions of Finf values pre- and post-interventions whereas the increased delivery of outdoor air via the building envelope by exhaust-only systems significantly increased Finf following retrofits.
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- Title
- Architecture as a Communicator of Values and Identity Spaces for Public Safety and Community Benefits
- Creator
- Waidele Arteaga, Nicolas
- Date
- 2022
- Description
-
Urban segregation, violence, and crimes are linked to drug trafficking. El Castillo Social Factory is an urban strategy that aims to recover...
Show moreUrban segregation, violence, and crimes are linked to drug trafficking. El Castillo Social Factory is an urban strategy that aims to recover the El Castillo neighborhood and prevent drug trafficking from advancing, understanding that police action is necessary but insufficient.This neighborhood is located on the southern periphery of Santiago in a commune called La Pintana and aspires to make its neighborhoods “more livable, healthy, and economically viable.” This proposal explores how investing in civic commons can make these goals a reality. First, it is essential to increase the presence of the State, strengthening existing services and adding new ones, with a focus on the care of children and young people. The second is to recover vacant lots and public spaces in poor condition or deteriorated through an “urban acupuncture” strategy based on the construction of many small or medium-sized projects. Art and sports are fundamental, allowing us to protect children and young people and offer them horizons of recreation and hope. The public buildings, institutions, land, water bodies, and infrastructure inherited from earlier generations are ready for us to see anew—as a robust network of civic assets ready to be activated for the current needs, desires, and dreams of all the people who share and shape them. El Castillo Social Factory offers a fresh look at our community anchors and the vibrant hubs our public spaces can become when we invest in collective urban life. Its vision focuses on positive transformation at the architectural scale—where personal experience and aspirations meet broad, long-range planning efforts—to spark the imagination and spur us to work together toward realizing the abundant potential of what we hold in common.
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