A process and system for continuous crystallization of a compound using antisolvent addition in which a solution is prepared with an organic... Show moreA process and system for continuous crystallization of a compound using antisolvent addition in which a solution is prepared with an organic compound and a solvent. An antisolvent is added to the solution in a continuous plug flow system comprising at least one process module. The antisolvent can be added in multiple addition points such that the overall amount of antisolvent added to the continuous plug flow reactor remains fixed. The multiple addition point technique provides every process module with an equal volume of antisolvent. Finally, crystals are recovered from the slurry upon exiting the system. Preferably, the mean crystal size is less than 100 μm. Sponsorship: Illinois Institute of Technology United States Patent Primary US Patent Classification 117/68 US Patent Classification 117/69 US Patent Classification 117/70 International Patent Classification C30B29/54 Show less
