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Title: Advertisement for Saturday Morning Children's Club at Chicago School of Design, 1944
Creator: Chicago School of Design
Date: 1944
Description: Advertisement for Saturday Morning Children's Club, a multidisciplinary children's art workshop offered by the Chicago School of Design,...
Show moreAdvertisement for Saturday Morning Children's Club, a multidisciplinary children's art workshop offered by the Chicago School of Design, featuring artwork by two local children. The date listed is uncertain, but inferred from the pencil notation on recto.
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Collection: Institute of Design records, 1937-ca. 1962

Title: Retrospective Quantitative T1 Imaging to Examine Characteristics of Multiple Sclerosis Lesions
Creator: Young, Griffin James
Date: 2024
Description: Quantitative MRI plays an essential role in assessing tissue abnormality and diseaseprogression in multiple sclerosis (MS). Specifically, T1...
Show moreQuantitative MRI plays an essential role in assessing tissue abnormality and diseaseprogression in multiple sclerosis (MS). Specifically, T1 relaxometry is gaining popularity as elevated T1 values have been shown to correlate with increased inflammation, demyelination, and gliosis. The predominant issue is that relaxometry requires parametric mapping through advanced imaging techniques not commonly included in standard clinical protocols. This leaves an information gap in large clinical datasets from which quantitative mapping could have been performed. We introduce T1-REQUIRE, a retrospective T1 mapping method that approximates T1 values from a single T1-weighted MR image. This method has already been shown to be accurate within 10% of a clinically available reference standard in healthy controls but will be further validated in MS cohorts. We also further aim to determine T1-REQUIRE’s statistical significance as a unique biomarker for the assessment of MS lesions as they relate to clinical disability and disease burden. A 14-subject comparison between T1-REQUIRE maps derived from 3D T1 weighted turbo field echoes (3D T1w TFE) and an inversion-recovery fast field echo (IRFFE) revealed a whole-brain voxel-wise Pearson’s correlation of r = 0.89 (p < 0.001) and mean bias of 3.99%. In MS white matter lesions, r = 0.81, R2 = 0.65 (p < 0.001, N = 159), bias = 10.07%, and in normal appearing white matter (NAWM), r = 0.82, R 2 = 0.67 (p < 0.001), bias = 9.48%. Mean lesional T1-REQUIRE and MTR correlated significantly (r = -0.68, p < 0.001, N = 587) similar to previously published literature. Median lesional MTR correlated significantly with EDSS (rho = -0.34, p = 0.037), and lesional T1-REQUIRE exhibited xiii significant correlations with global brain tissue atrophy as measured by brain parenchymal fraction (BPF) (r = -0.41, p = 0.010, N = 38). Multivariate linear regressions between T1- REQUIRE NAWM provided meaningful statistical relationships with EDSS (β = 0.03, p = 0.027, N = 38), as well as did mean MTR values in the Thalamus (β = -0.27, p = 0.037, N = 38). A new spoiled gradient echo variation of T1-REQUIRE was assessed as a proof of concept in a small 5-subject MS cohort compared with IR-FFE T1 maps, with a whole brain voxel-wise correlation of r = 0.88, R2 = 0.77 (p < 0.001), and Bias = 0.19%. Lesional T1 comparisons reached a correlation of r = 0.75, R2 = 0.56 (p < 0.001, N = 42), and Bias = 10.81%. The significance of these findings means that there is the potential to provide supplementary quantitative information in clinical datasets where quantitative protocols were not implemented. Large MS data repositories previously only containing structural T1 weighted images now may be used in big data relaxometric studies with the potential to lead to new findings in newly uncovered datasets. Furthermore, T1-REQUIRE has the potential for immediate use in clinics where standard T1 mapping sequences aren’t able to be readily implemented.
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Title: Utilizing Image Processing in Evaluation of Fibroblast Stimulation for Collagen Remodeling
Creator: Yoon, Shin Hae
Date: 2023
Description: This research delves into the realm of image processing as a pivotal component in the evaluation of fibroblast stimulation for collagen...
Show moreThis research delves into the realm of image processing as a pivotal component in the evaluation of fibroblast stimulation for collagen remodeling. The study focuses on unraveling the intricate synergy between electrospun silk fibroin-carbon nanotube (SF-CNT) fibers and electrical stimulation, working in harmony to enhance tissue regeneration. Building upon our previous work, we successfully engineered SF-CNT fibers through the electrospinning process, yielding highly aligned structures reminiscent of natural extracellular matrix proteins. These fibers were fortified with water stability through post-treatment with ethanol vapor, while subtle additions of carbon nanotubes (CNTs) significantly improved fiber alignment, strength, and conductivity without compromising biocompatibility. This innovative platform served as a cell culture matrix for fibroblasts harvested from pelvic organ prolapse (POP) patients, facilitating electrical stimulation that triggered a substantial increase in collagen production. In this study, we harnessed the power of various image-processing software tools, including ImageJ and Python, to analyze immunostained images of fibroblasts obtained from POP patients. Under carefully tailored electrical stimulation conditions, the stimulated cells exhibited an astonishing up to 11.97-fold increase in alpha-smooth muscle actin (α-SMA) expression, unequivocally signifying the successful activation of myofibroblasts. Additionally, in an animal model employing LOX-knockout mice to mimic collagen disorders associated with POP, the application of optimized electrical stimulation conditions for patient 003 led to a remarkable surge in collagen production and structural enhancement, underlining the potential of electrical stimulation in expediting tissue remodeling. Intriguingly, fibroblasts from patient 005 and patient 006 exhibited a distinct response, shedding light on the influence of POP severity on cellular behavior. This study firmly reinforces the imperative of personalized therapeutic approaches, emphasizing the need to customize treatment strategies to align with individual patient characteristics through innovative biological image analysis techniques.
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Title: Effect of organic acid treatment in reducing Salmonella on six types of sprout seeds
Creator: Yang, Dachuan
Date: 2023
Description: Fresh sprouts present a special food safety concern as their growing conditions also favor the growth of pathogens such as Salmonella....
Show moreFresh sprouts present a special food safety concern as their growing conditions also favor the growth of pathogens such as Salmonella. Contamination in sprouts often originates from the seeds used for sprouting. The Produce Safety Rule requires that seeds used to grow sprouts be treated to reduce pathogens. The treatments may be applied by sprout growers or by seed suppliers. Although 20,000 ppm calcium hypochlorite is the most used seed treatment method, the high chlorine level can be hazardous to workers and the environment. Alternative seed treatment methods that are safe and environmentally friendly are needed. In addition, a post-treatment drying step is needed when seed suppliers are using chemical seed treatment methods. This study evaluated the efficacy of an organic acid solution for reducing Salmonella on six types of seeds (alfalfa, clover, radish, mung bean, onion, and broccoli). The impact of treatment on seed germination and sprout yield was also examined. Ten grams of seeds inoculated with a five-serotype cocktail of Salmonella were pre-rinsed with 40 ml of water twice and treated with 75.7 ml of the organic acid solution for 1 hour. The treated seeds were either not rinsed or rinsed with 40 ml of water twice before being dried in the biological safety cabinet for 24 hours. The Salmonella level, germination percentage, and sprout yield of seeds treated with water, seeds treated with the organic acid solution, seeds treated with organic acid, dried, and rinsed, and seeds treated with organic acids, dried, and not rinsed were compared. Salmonella reductions that could be achieved with this organic acid solution treatment were less than 0.5 log CFU/g without drying, 0.6-2.0 log CFU/g with drying and rinse, or 1.6-2.9 log CFU/g with drying and no rinse. Drying significantly enhanced the treatment efficacy (p < 0.05 ) on alfalfa, radish, mung bean, and onion seeds. If seeds were not rinsed after treatment, the log reductions achieved on mung bean and onion seeds were significantly higher (p < 0.05). If seeds were treated and rinsed, the germination rates of six types of seeds were not affected (p > 0.05) regardless of whether the seeds were dried or not. All treatments significantly decreased the sprout yield of clover seeds by 13% (p < 0.05 ). If seeds were not rinsed after treatment, the germination rates of clover and broccoli seeds were reduced by 7 and 9%, respectively, and the sprout yield of alfalfa seeds was reduced by 35%. Overall, the organic acid solution was ineffective when compared with 20,000 ppm calcium hypochlorite in reducing Salmonella on sprout seeds, although the drying step after treatment could improve the treatment efficacy.
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Title: Grace Gospel Mission, Chicago, Illinois, ca. 1945
Creator: Illinois Institute of Technology
Date: 1943-1948
Description: Photograph of the front of Grace Gospel Mission, 3138(?) South State Street. This storefront church was demolished ca. 1950. Date of...
Show morePhotograph of the front of Grace Gospel Mission, 3138(?) South State Street. This storefront church was demolished ca. 1950. Date of photograph is unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Grand View Blvd...Los Angeles Jan 91
Creator: Gordon, Robert Philip
Date: 1991-01
Description: Watercolor painting of the intersection of an unknown street with Grand View Boulevard in Los Angeles, California.
Collection: Robert Philip Gordon papers, 1963-2010

Title: New Object
Creator: Zhang, He

Title: Ink and Pastel Drawing, undated
Creator: Henry, Mary Dill, 1913-2009
Description: Untitled ink and pastel drawing by Mary Henry of a hand, possibly her own. Drawing is undated.
Collection: Mary Dill Henry Papers, 1913-2021

Title: Bronzeville, Chicago, Illinois, 1961
Date: 1961
Description: Color photograph depicting the Bronzeville neighborhood in 1961. Coverage includes the 3400 south blocks of Michigan Avenue, Indiana Avenue,...
Show moreColor photograph depicting the Bronzeville neighborhood in 1961. Coverage includes the 3400 south blocks of Michigan Avenue, Indiana Avenue, Prairie Avenue, and Calumet Avenue in Chicago, Illinois. One newer white commercial building at the left is the former Chicago Defender building. Photographer unknown.
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Collection: Bronzeville photo, 1961

Title: Gospel Mission Baptist Church, Chicago, Illinois, ca. 1945
Creator: Illinois Institute of Technology
Date: 1943-1948
Description: Photograph of the front of the Gospel Mission Baptist Church. Date of photograph is unknown. Date range listed is approximate.
Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Design on a Hill
Creator: Henry, Mary Dill, 1913-2009, Ziegler, William
Description: Photograph of Design on a Hill (1940), a stone lithograph by Mary Dill Henry, completed as a part of her studies with Ray Bertrand....
Show morePhotograph of Design on a Hill (1940), a stone lithograph by Mary Dill Henry, completed as a part of her studies with Ray Bertrand. Handwritten inscription on verso: "Lithograph #2, 1940 Federal Art Project, litho pencil on stone. Ray Bertrand, San Francisco Art Project, was my teacher." Typewritten inscription on verso: "Mary Henry: Design on a Hill, 1940. Stone lithograph, 12" x 16". Courtesy of the artist, Freeland, WA. Photo: Wm. Ziegler." Photograph by William Ziegler. Date of photograph unknown.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: Federal Arts Project mosaic, Monterey, California
Description: Photograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s,...
Show morePhotograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s, described on the inscription of a similar photograph as "Mary Dill's first mosaic for the Federal Art Project - the first governor's house in Monterey, Calif." Photographer unknown. Date of photograph unknown.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: Federal Arts Project mosaic, Monterey, California
Description: Photograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s,...
Show morePhotograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s, described on the inscription of a similar photograph as "Mary Dill's first mosaic for the Federal Art Project - the first governor's house in Monterey, Calif." Photographer unknown. Date of photograph unknown.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: Federal Arts Project mosaic, Monterey, California
Description: Photograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s,...
Show morePhotograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s, described on the inscription of a similar photograph as "Mary Dill's first mosaic for the Federal Art Project - the first governor's house in Monterey, Calif." Photographer unknown. Date of photograph unknown.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: Federal Arts Project mosaic, Monterey, California
Description: Photograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s....
Show morePhotograph of a mural completed in Monterey, California as part of a the Federal Arts Project by Mary Dill, likely in the late 1930s. Inscription on verso: "Mary Dill's first mosaic for the Federal Art Project - the first governor's house in Monterey, Calif." Photographer unknown. Date of photograph unknown.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: An architectural and structural study of multi-storied skeleton building
Creator: Lempp Kerbis, Gertrude 1926-2016
Date: 1954

Title: Plate 5
Creator: Henry, Mary Dill, 1913-2009
Date: 1936-1939
Description: Untitled ink drawing identified on recto as "Plate 5." Date of drawing is unknown. Date range listed is approximate.
Collection: Mary Dill Henry Papers, 1913-2021

Title: Ink Drawings, 1981
Creator: Henry, Mary Dill, 1913-2009
Date: 1981-02-17
Description: Untitled ink drawings by Mary Henry. Inscription on verso reads "8' x 6' Feb 17 81" and also contains what appear to be mathematical...
Show moreUntitled ink drawings by Mary Henry. Inscription on verso reads "8' x 6' Feb 17 81" and also contains what appear to be mathematical calculations.
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Collection: Mary Dill Henry Papers, 1913-2021

Title: Students building a snowman, Illinois Institute of Technology, Chicago, Illinois, 1980s
Creator: Lightfoot, Robert M., III
Date: 1980-1989
Description: Photograph of students building a snowman on present day Siegel Field, north of S.R. Crown Hall on the Illinois Tech campus. Date of...
Show morePhotograph of students building a snowman on present day Siegel Field, north of S.R. Crown Hall on the Illinois Tech campus. Date of photograph is unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Spring Thing tricycle race, Illinois Institute of Technology, Chicago, Illinois, ca. 1968-1971
Date: 1968-1971
Description: Photograph of the tricycle race during the Spring Thing. Spring Thing, sponsored by the Union Board, occurred during the fall semester,...
Show morePhotograph of the tricycle race during the Spring Thing. Spring Thing, sponsored by the Union Board, occurred during the fall semester, usually in October. The tricycle race, first held in 1968, was a highlight of the annual festivities. Photographer unknown. Date of photograph is unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

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