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Title: Estimation of Future Glucose Concentrations with Subject-Specific Recursive Linear Models
Creator: Eren-oruklu, Meriyan, Cinar, Ali, Quinn, Lauretta, Smith, Donald
Date: 2009-04
Publisher: MARY ANN LIEBERT INC
Description: Background: Estimation of future glucose concentrations is a crucial task for diabetes management. Predicted glucose values can be used for...
Show moreBackground: Estimation of future glucose concentrations is a crucial task for diabetes management. Predicted glucose values can be used for early hypoglycemic/hyperglycemic alarms or for adjustment of insulin injections or insulin infusion rates of manual or automated pumps. Continuous glucose monitoring (CGM) technologies provide glucose readings at a high frequency and consequently detailed insight into the subject's glucose variations. The objective of this research is to develop reliable subject-specific glucose prediction models using CGM data. Methods: Two separate patient databases collected under hospitalized (disturbance-free) and normal daily life conditions are used for validation of the proposed glucose prediction algorithm. Both databases consist of glucose concentration data collected at 5-min intervals using a CGM device. Using time-series analysis, low-order linear models are developed from patients' own CGM data. The time-series models are integrated with recursive identification and change detection methods, which enables dynamic adaptation of the model to inter-/intra-subject variability and glycemic disturbances. Prediction performance is evaluated in terms of glucose prediction error and Clarke Error Grid analysis (CG-EGA). Results: Prediction errors are significantly reduced with recursive identification of the models, and predictions are further improved with inclusion of a parameter change detection method. CG-EGA analysis results in accurate readings of 90% or more. Conclusions: Subject-specific glucose prediction strategy has been developed. Including a change detection method to the recursive algorithm improves the prediction accuracy. The proposed modeling algorithm with small number of parameters is a good candidate for installation in portable devices for early hypoglycemic/hyperglycemic alarms and for closing the glucose regulation loop with an insulin pump.
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Title: Performance Addendum: Filing the Void
Creator: Edwards, David
Date: 2012-04-24, 2012-05
Description: This project was done as a response to the thriving public performance community at the northern side of Grant park in Chicago, IL. As a...
Show moreThis project was done as a response to the thriving public performance community at the northern side of Grant park in Chicago, IL. As a former resident of the South Loop a rift was readily perceived between the North and South ends of the park in both venues for entertainment as well as general amenities. This project looked to fill a void on the south end of the park to create both a more welcoming outdoor space for the public but also to create a performance venue that could help bring business and pedestrian traffic to the southern end of the loop.
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Title: DEPTH MAP PROCESSING FOR MULTI-VIEW VIDEO PLUS DEPTH
Creator: Vijayanagar, Krisha Rao
Date: 2014, 2014-05
Description: The world of multimedia and visual entertainment has grown in leaps and bounds in the past decade with 3-D television being one of the biggest...
Show moreThe world of multimedia and visual entertainment has grown in leaps and bounds in the past decade with 3-D television being one of the biggest technologies. Amongst several formats proposed for representing 3-D content, multi- view video plus depth (MVD) format has gained a lot of interest in the past few years. MVD requires that each view of a particular scene be accompanied by a per-pixel depth. This introduces new problems for compression and transmission of MVD content because a depth map has di erent characteristics from a color image. Keeping the MVD format and depth map characteristics in mind, we highlight three majors problems that plague the MVD format, namely, 1. depth map re nement. 2. depth map compression. 3. novel view synthesis using the depth map at the decoder side. In order to re ne a depth map, we propose a multi-resolution anisotropic di usion algorithm that is optimized to run in real-time thus ensuring that the encoder does not su er from additional latency. Next, we propose two unique solutions for compressing them. We rst propose a solution using the Layered Depth Video (LDV) concept using a rate-distortion optimized quadtree decomposition of the LDV using a novel two-mode block truncation code with improved prediction. We also propose a compression solution using compressive sensing (CS) concepts by creating a hybrid rate-optimized CS codec. This codec achieves two goals:- rstly, block classi cation to ensure lower decoder complexity and secondly, rate-distortion optimization of the measurement rate for each block that is to be compressively sensed. We then look at the view synthesis component of the MVD tool-chain which x is a time-sensitive process. Keeping decoding latency in mind, we propose a lookup- table based approach to the 3-D warping process with a simpli ed hole- lling algorithm that is not only competitive quality-wise with other schemes but is several times faster too. It is hopeful that the presented techniques can be used successfully to create MVD architectures for applications that need low-complexity encoding solutions.
PH.D in Electrical Engineering, May 2014
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Title: PHOTONASTIC Innovative Facade Technology: L.ROMERO_FINAL_BOARD_1
Creator: Romero, Loretta
Date: 2012-04-24, 2012-05
Description: PHOTONASTIC is a concept addressing the invention, design, production and potential implementation of a building integrated system. The system...
Show morePHOTONASTIC is a concept addressing the invention, design, production and potential implementation of a building integrated system. The system attempts to address the relationship between energy conservation and architectural facade innovation. The skin affects both the appearance and performance in such a way that these features promote new design concepts and stimulate technical developments for the architecture of the future.
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Title: Inspection System and Method
Creator: Hansen, Wilbur W.
Date: 1961-07-25
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: Selector System for Magnetic Wire Reproducers
Creator: Danisch, Marion S.
Date: 1949-09-06
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: COMPUTER MODELING OF BREAST LESIONS AND STUDIES OF ANALYZER-BASED X-RAY IMAGING
Creator: Garcia, Luis De Sisternes
Date: 2011-11, 2011-12
Description: Phase-contrast x-ray imaging is an emerging technique that promises to yield highly sensitive medical images of soft tissue, which is...
Show morePhase-contrast x-ray imaging is an emerging technique that promises to yield highly sensitive medical images of soft tissue, which is difficult to observe via conventional radiography given its low X-ray attenuation differences. One of these phase-contrast techniques, known as analyzer-based imaging, has demonstrated that highly detailed breast tissue images can be obtained using synchrotron radiation. However, synchrotron facilities are impractical for clinical use. This thesis introduces studies and exposure consideration towards the application of analyzer-based imaging in a clinical environment, particularly in the context of breast imaging. It also introduces a computational breast lesion model that generates randomized three-dimensional phantoms which follow realistically the characteristics observed in real lesions. Moving analyzer-based imaging to clinical application requires the consideration of photon noise, inherent from the use of a photon-limited conventional source. We summarize the statistical properties in the presence of photon noise of two popular analyzer-based imaging techniques, known as diffraction-enhanced imaging (DEI) and multiple-image radiography (MIR). The statistics for MIR have not been previously derived and are introduced in this thesis. Comparison of the resulting statistical predictions with results obtained by Monte Carlo simulation validated the analysis. An expression for the maximum-likelihood (ML) solution for analyzer-based imaging is presented as a way of minimizing the effects of photon noise in the reconstruction of the object’s absorption, refraction and ultra-small angle scattering properties, and more practical maximum-likelihood expectation-maximization (ML-EM) and maximum-a-posteriori expectation-maximization (MAP-EM) solutions are also introduced. The behavior of the ML-EM and MAP-EM solutions was compared to the results produced by the five best-known analyzer-based reconstruction methods using computer simulations. The ML-EM and MAP-EM reconstructions proved closer to the theoretical values as they do not rely on commonly known limitations and approximations introduced by the other techniques. We introduce the development and evaluation of a new computational breast lesion phantom model that can simulate either massess or microcalcifications. The proposed tool allows the generation of a large number of randomized three-dimensional breast lesion simulations following desired characteristics normally used to describe breast lesions in clinical practice. The initial motivation for the development of this new phantom model was to enable the proposed evaluations of analyzer-based imaging to be achieved. However, the model became a major focus of this thesis because it improves significantly upon those that can be found in previous literature. The proposed lesion model can be used for evaluation studies across different breast imaging techniques, as well as for training purposes, so it is our hope that it could become an important resource for the broader mammography research community. As part of the lesion modeling research, we also introduce methods to computationally modify experimental mammography and analyzer-based images of breast tissue so that they present the generated tumor simulations embedded within their parenchyma realistically. The realism of the simulated lesion images was evaluated by comparison of 83 real tumor cases observed in mammograms with 83 constructed hybrid images in which simulated tumors matching the characteristics observed in the real cases were embedded, with healthy tissue acting as background. As a quantitative comparison, extracted features describing tumor shape and density showed no statistically significant differences between real and simulated tumors. A known computational tumor classification technique based on their shape observed in mammography was implemented and showed no significant performance differences between real and simulated cases, as well as showing good correlation with previously published performance results in real tumors. To measure the realism for use in human observer studies, we conducted a reader study in which 5 experienced radiologists were asked to judge whether each of the 166 images was real or simulated by assigning a score on a 7-point scale. The results were analyzed in a multiple-reader multiple-case statistical framework. The conclusion of the study was that the readers’ accuracy in assessing whether the lesions were real or simulated was not significantly better than random chance. This thesis also incorporates a reader study to evaluate the degree to which photon-limited analyzer-based images may be effective for visualization of breast cancer features. Our motivation was to establish the x-ray intensity that would be required to make these methods feasible, the purpose being to serve as a guide in parameter selection for future design of imaging hardware. We conducted a series of observer studies that quantify the performance of analyzer-based refraction images at different noise levels for the task of identifying subtle details present in breast tumors which are relevant to clinical diagnosis. The cases shown to the readers consisted of hybrid images where simulated lesions of known characteristics were computationally embedded in real breast analyzer-based background images. The original phase-contrast data was obtained using synchrotron radiation and was later modified to simulate the noise and blurring effects produced from a photon-limited source with a 300μm aperture size, similar to those used in a laboratory environment. Results showed that the analyzer-based imaging techniques statistically outperformed conventional mammography for the given task with an average of just 128 recorded photons per pixel in background image regions
Ph.D. in Electrical Engineering, December 2011
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Title: FEASIBILITY OF INDICATOR MICROORGANISMS IN ASSESSING THE EFFICACY OF SANITIZERS IN FRESH PRODUCE WASHING
Creator: Zhong, Zeyan
Date: 2016, 2016-05
Description: Sanitizers have been widely used in controlling cross-contamination during fresh produce washing processes. It is important to identify...
Show moreSanitizers have been widely used in controlling cross-contamination during fresh produce washing processes. It is important to identify different approaches for monitoring the efficacy of sanitizer washing. In this study, our objective was to determine the feasibility of indicator microorganisms in assessing the efficacy of chlorine and peroxyacetic acid (PAA) in fresh-cut produce washing. In inactivation experiments, the survivals of inoculated indicator microorganisms [total viable count (TVC), Enterobacteriaceae and total coliforms] and E. coli O157:H7 were determined after exposure to different concentrations of chlorine or PAA in water with added organic load (TOC~200 mg/l). In small-scale washing experiments, bacterial transfer from lettuce leaves inoculated with indicators or E. coli O157:H7 to wash water containing chlorine or PAA with/without organic matters was evaluated. In the inactivation study, higher log reduction was observed for Enterobacteriaceae and total coliforms than for E. coli O157:H7 after chlorine treatment at an initial concentration of 30 ppm. In the bacterial transfer study [a inoculated leaf (~5 log CFU) in 30 ml of wash water], without additional organic matter, approximately 3.5 log total CFU of all bacteria groups was transferred into wash water. Less than 1.5 log total CFU were detected for Enterobacteriaceae, total coliforms and E. coli O157:H7 in 1 ppm chlorine washing. With introduced organic matter, similar microbial loads of Enterobacteriaceae, total coliforms and E. coli O157:H7 were detected on washed leaves and in wash water with initial chlorine concentration of 1 ppm; when initial chlorine level increased to 10 ppm, less than 2 log total CFU of Enterobacteriaceae and total coliforms was detected while about 3 log total CFU of E. coli O157:H7 transferred to wash water, suggesting that chlorine at an initial concentration of 10 ppm could not prevent cross-contamination in the presence of organic load. The indicators showed different levels of survival and transfer from E. coli O157:H7 in this study and were unreliable to effectively monitor the behavior of the pathogen during chlorine wash in fresh produce processes. Enterobacteriaceae and total coliforms were more vulnerable to 40 ppm PAA treatment than E. coli O157:H7 in PAA inactivation experiments. No survival, except for TVC, was observed after 80 ppm of PAA inactivation. In the bacterial transfer study, 40 ppm PAA in wash water was found unable to prevent cross-contamination of indicators and E. coli O157:H7 from leaves to water. Further investigation is needed to compare the bacterial transfer levels of E. coli O157:H7 and the indicators at higher PAA levels.
M.S. in Food Safety and Technology, May 2016
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Title: Nutrition and Diabetes: Pathophysiology and Management
Creator: Opara, Emmanuel C.
Date: 2006
Publisher: CRC, Taylor & Francis

Title: COOPERATIVE BATCH SCHEDULING FOR HPC SYSTEMS
Creator: Yang, Xu
Date: 2017, 2017-05
Description: The batch scheduler is an important system software serving as the interface between users and HPC systems. Users submit their jobs via batch...
Show moreThe batch scheduler is an important system software serving as the interface between users and HPC systems. Users submit their jobs via batch scheduling portal and the batch scheduler makes scheduling decision for each job based on its request for system resources and system availability. Jobs submitted to HPC systems are usually parallel applications and their lifecycle consists of multiple running phases, such as computation, communication and input/output data. Thus, the running of such parallel applications could involve various system resources, such as power, network bandwidth, I/O bandwidth, storage, etc. And most of these system resources are shared among concurrently running jobs. However, Today's batch schedulers do not take the contention and interference between jobs over these resources into consideration for making scheduling decisions, which has been identified as one of the major culprits for both the system and application performance variability. In this work, we propose a cooperative batch scheduling framework for HPC systems. The motivation of our work is to take important factors about jobs and the system, such as job power, job communication characteristics and network topology, for making orchestrated scheduling decisions to reduce the contention between concurrently running jobs and to alleviate the performance variability. Our contributions are the design and implementation of several coordinated scheduling models and algorithms for addressing some chronic issues in HPC systems. The proposed models and algorithms in this work have been evaluated by the means of simulation using workload traces and application communication traces collected from production HPC systems. Preliminary experimental results show that our models and algorithms can effectively improve the application and the system overall performance, HPC facilities' operation cost, and alleviate the performance variability caused by job interference.
Ph.D. in Computer Science, May 2017
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Title: APPLICABILITY OF THE INTERVAL ANALYSIS METHOD TO RELIABILITY ASSESSMENT OF STRUCTURES
Creator: Taha, Raguez A.
Date: 2012-11-26, 2012-12
Description: The scope of this study is focused on the applicability of the interval method to the reliability analysis of structures. The study includes...
Show moreThe scope of this study is focused on the applicability of the interval method to the reliability analysis of structures. The study includes using the traditional probability methods in several applications and comparing the results with the interval analysis. Accordingly, the interval arithmetic rules are applied in several examples and the results are compared with those from the traditional probability theory concepts. Specifically, the procedure for using the interval methods was applied to the development of the probability of failure for a simple structural member; and for a link in a network system. Through three simple examples, the research shows that the interval method offers comparable results with those from the traditional first-order reliability method. The procedure based on the interval method, however, may offer advantages, especially in cases where the uncertainties in various parameters describing the reliability of a system are large. In the presence of large uncertainties, the traditional methods of reliability analysis, based on the first order approximation, may lose their accuracy. In these cases, the interval method may offer a simple method yet with more accurate results.
M.S. in Civil Engineering, December 2012
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Title: Cobalt Alloys
Creator: Levinson, David W., Mcandrew, Joseph B., Metcalfe, Arthur G.
Date: 1961-05-09
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: Magazine for Magnetic Recording Apparatus
Creator: Greenleaf, Leland B.
Date: 1950-08-15
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: Magnetic Pick-up Head
Creator: Wiegand, David E.
Date: 1959-12-22
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: Integrator and Hysteresis Loop Tracer
Creator: Wiegand, David E.
Date: 1952-09-09
Description: Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent

Title: A FAT home: Boards_aFAThome_01
Creator: Szajna, Conrad
Date: 2012, 2012-05
Description: The aim of this thesis is to revitalize suburban subdivisions not by destroying existing typology but by using the typical cookie cutter homes...
Show moreThe aim of this thesis is to revitalize suburban subdivisions not by destroying existing typology but by using the typical cookie cutter homes as a basis for re-envisioning subdivisions. By creating key room components, existing homes can expand outward to provide additional rooms for current family members, for older generations moving back home and/or for additional rental spaces as a way to supplement income. The end result creates unique spaces and courtyards that places the resident much closer to nature.
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Title: STUDY OF VITREOSCILLA HEMOGLOBIN VARIANTS PRODUCED BY RANDOM MUTAGENESIS
Creator: Lin, Xiaodan
Date: 2015, 2015-05
Description: This study is focused on comparing the wild type and mutated versions of the Vitreoscilla hemoglobin gene (vgb). The purpose of this focus is...
Show moreThis study is focused on comparing the wild type and mutated versions of the Vitreoscilla hemoglobin gene (vgb). The purpose of this focus is to find out whether any of the vgb mutations provides an advantage regarding cell growth rate, as well as on the expression level of Vitreoscilla hemoglobin protein (VHb). A negative control Escherichia coli DH5α (E. coli DH5α) bearing no pUC plasmid, as well as seven E. coli DH5α strains bearing different pUC-based plasmids were tested in the experiments. Among these were one vector-only negative control (pUC18), one wild type positive control (pUC8:16, which carries wild type vgb) and five different types of pUC-bearing vgb mutants (pUC-vgb M1, M2, M3, M4 and pUC18-vgb M3). In order to compare cell growth rate among these strains, the growth rate assay was carried out under three different conditions: (1) Luria-Bertani (LB) medium, aerobic conditions; (2) Terrific Broth (TB) medium, low oxygen conditions; and (3) TB medium, microaerobic conditions. In addition, the carbon monoxide (CO) difference spectra assay was conducted to measure functioning VHb protein expression levels for the strains grown under aerobic conditions. In contrast to the results obtained by our Australian collaborators, our growth rate assay and CO difference spectra assay showed no growth advantage or higher expression level of functioning VHb protein due to any of the vgb mutations. For the further study of the vgb mutants, four different recombinant plasmids were constructed by cloning three types of mutated vgb (vgb M1, M3 and M4) as well as wild type vgb into the prokaryotic expression vector pUC8 with ampicillin (Amp) resistance. After being transformed into competent E. coli DH5α cell, these resulting xii strains, as well as the plasmid-free negative control (E. coli DH5α) and vector-only negative control (E. coli DH5α bearing plasmid pUC8) were tested by the CO difference spectra assay. Except strain E. coli DH5α [pUC8-vgb M3], which showed a slight increase in the VHb expression level, the strain bearing other mutated vgbs did not demonstrate any elevation in VHb protein expression level, compared to the positive control containing wild type vgb.
M.S. in Biology, May 2015
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Title: FUNCTIONAL ANALYSIS OF POTENTIAL PHOSPHORYLATION SITES IN BAXΔ2 UNIQUE OLIGOPEPTIDE
Creator: Tsai, Yu-tseng
Date: 2014, 2014-07
Description: The tumor suppressor gene, Bax, plays a critical role in tumor progression through regulating cell apoptosis. Mutations on the BAX gene often...
Show moreThe tumor suppressor gene, Bax, plays a critical role in tumor progression through regulating cell apoptosis. Mutations on the BAX gene often result in silencing its expression and the loss of pro-death ability. However, there is a unique Bax isoform, BaxΔ2, recently discovered in these Bax mutated cancer cells. BaxΔ2 isoform shows higher pro-apoptotic activity than Baxα. Unlike the parental Baxα, BaxΔ2 does not target mitochondria and forms aggregates in cytosol. There is a unique 10-amino-acid peptide in the N-terminus of BaxΔ2 protein possible function as a special signal. Two serines in this region are predicted as potential phosphorylation sites for regulation of the protein activity. To test this hypothesis, we mutated both serines (SS) into non-phosphorylatable alanines (AA) by site-directed mutagenesis approach. Both BaxΔ2 wild type (BaxΔ2-SS) and mutants (BaxΔ2-AA) were tagged with GFP, which allows us to monitor the protein expression and cellular localization in live cells. Here, we found that the distribution patterns of BaxΔ2-AA and BaxΔ2-SS were similar and appeared as aggregates in cytosol. BaxΔ2-AA mutant also possessed the similar pro-apoptotic activity with BaxΔ2-SS wild type. These results suggested that the two serines in BaxΔ2 unique oligopeptide might not play a critical role in BaxΔ2 localization and pro-death activity under the current ectopic expression conditions. Further study is needed to have better understanding of phosphorylation in contribution to unique behavior of BaxΔ2.
M.S. in Biology, July 2014
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Title: Synthesis of Therapeutic and Diagnostic Drugs Centered on Regioselective and Stereoselective Ring Opening of Aziridinium Ions
Creator: Chong, Hyun-soon
Date: 2016-09-21, 2016-09-20
Description: Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in...
Show moreStereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in steroselective and regioselective synthesis of therapeutic and diagnostic compounds
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: The utilization of sunflower stalks in paper manufacture
Creator: Zavertnik, J.
Date: 2009, 1914
Publisher: Armour Institute of Technology
Description: http://www.archive.org/details/utilizationofsun00zave
Thesis (B.S.)--Armour Institute of Technology

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