Human exposure to ambient pollutants such as particulate matter, ozone, and oxides of nitrogen are associated with a variety of adverse health... Show moreHuman exposure to ambient pollutants such as particulate matter, ozone, and oxides of nitrogen are associated with a variety of adverse health effects in epidemiology studies. However, much of human exposure to outdoor pollutants occurs inside residential buildings where people spend the majority of their time. One important determinant of indoor exposures to pollutants of outdoor origin is the “penetration factor” of the building envelope, which characterizes the ability of the building enclosure assembly to filter outdoor air as it infiltrates indoors. To date, measurements of envelope penetration factors for various outdoor pollutants in real indoor environments remain extremely limited, in part because current methods suffer from high costs, high uncertainty, and high levels of invasiveness presented to building occupants. Therefore, the research objectives in this dissertation aims to (1) develop and/or refine (as applicable) methods to measure the penetration of outdoor particulate matter, ozone, and nitrogen oxides in buildings and (2) apply them to characterize a diverse sample of residential buildings in Chicago, IL, including single-family homes, multi-family homes, and homes before and after they undergo energy efficiency retrofits. Results from this research will provide refined methods that others can use in field measurements and novel data for modelers to better assess indoor exposures to outdoor pollutants, which can then be used to improve exposure assessments for epidemiology studies. Show less