The primary aim of this study is to address the neuropsychological functioning of adults with Sickle Cell Disease (SCD) by examining the... Show moreThe primary aim of this study is to address the neuropsychological functioning of adults with Sickle Cell Disease (SCD) by examining the association of illness-related and psychosocial factors with cognition. The neuropsychological functioning of adults with SCD will be compared to that of controls matched on gender, race, and age. There is considerable evidence for neuropsychological complications associated with SCD (Anie, 2005; Schatz, 2004). Much of the cognitive deficits are thought to be the result of cerebrovascular accidents commonly suffered by this population. Studies of cognition in children with SCD suggest that cognitive complications tend to increase with age. Particularly implicated are deficits in attention, concentration, and executive functioning. Although the specific neuropsychological morbidity is not as clearly understood for adults with SCD as it is for children, global cognitive impairment within this population has been documented. In addition, pain negatively affects cognitive functioning in both children and adults (Libon et al., 2010). The pattern of impairment was suggested to be the result of additional demands on attentional capacity. However, the relationship between pain and cognitive performance in adults with sickle cell disease is less clear. As a result of frequent pain, individuals with SCD often report a low evaluation of quality of life particularly as a result of health complaints (Anie, 2005). Thus, the inter-dynamic of health -related quality of life, pain , and cognitive dysfunction is not entirely clear within the sickle cell population and therefore warrants examination. PH.D in Psychology, July 2013 Show less
Query
(-) mods_name_creator_namePart_mt:"Vernale Iii, Michael A."
