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Title: Development of a Model To Investigate Inflammation Using Peripheral Blood Mononucleated Cells
Creator: Geevarghese Alex, Peter
Date: 2023
Description: Our modern culture in our society is facing one of the biggest risks in health which is high-calorie diet-related postprandial inflammation....
Show moreOur modern culture in our society is facing one of the biggest risks in health which is high-calorie diet-related postprandial inflammation. Chronic diseases may be caused if the energy-dense food is the choice meaning if it is uncontrolled, clinical studies have demonstrated this with the body's post-meal inflammatory response. We aimed to find the causes of postprandial inflammation in response to various dietary treatments and provide a model to demonstrate. We aimed to make use of in vivo and in vitro techniques and statistics to create a model. The created model would help us to design specific treatments to minimize inflammation with response to dietary. In addition to figuring out vital dietary additives, the model additionally facilitates the layout of individualized interventions to reduce inflammation, thereby improving long-time period health outcomes. We aim to understand the clinical observations of diet-induced postprandial inflammation on the molecular level. We desire to make contributions to reduce the impact of chronic inflammatory disorders that is associated with postprandial inflammation.
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Title: Quantifying the Sorption Behavior of Polypropylene Toward Methyl Salicylate and Phenylcyclohexane Under FDA Surrogate Testing Protocol for Recycled Plastics Use in Food Contact Materials
Creator: Senthilkumaran, Senthamizh Kumaran
Date: 2024
Description: The increasing use of recycled polypropylene in food packaging raises concerns about chemical migration. FDA’s surrogate testing protocol...
Show moreThe increasing use of recycled polypropylene in food packaging raises concerns about chemical migration. FDA’s surrogate testing protocol using hexane or heptane as a diluent has evaluated the efficiency of industrial recycling processes in removing contaminants from reclaimed polyethylene terephthalate (PET). Different conditions to optimize surrogate testing of polypropylene (PP) may be needed due to the different sorption behavior of PP relative to PET. This study examines how the interaction between the surrogate contaminant, diluting solvent, and polymer impacts the sorption of surrogate contaminants into PP. Methyl salicylate (MS) and phenylcyclohexane (PCH) were selected as surrogate contaminants based on the current FDA testing protocol and solubility parameters. Swelling and sorption experiments were performed at 40°C for up to 14 days on different types of PP (monophasic homopolymer polypropylene (h-PP), monophasic random copolymer (r-PP), and/or heterophasic block copolymer (heco-PP)) in n-hexane, 2-propanol, and ethanol as diluting solvents. Sorption of 1% (v/v) MS and PCH from each diluting solvent into h-PP was quantified by GC-MS. Results showed that the PP polymers in n-hexane swelled 10%-155% more than the alcohols. Both MS and PCH sorption in n-hexane required a much shorter time, approximately 12 h, to reach equilibrium in comparison to the alcohols, which required 2–10 days. The equilibrium sorption concentration of 1% MS into h-PP from n-hexane was 55% and 136% higher, respectively, compared to sorption of MS from 2-propanol and ethanol. On the other hand, the equilibrium sorption concentration of 1% PCH into h-PP from 2-propanol and ethanol was 11-12% higher compared to the sorption of MS from n-hexane. Our data indicates that solvent swelling cannot be overlooked when determining realistic initial contamination levels in PP. This research will assist the FDA in updating the Recycled Plastics Guidance for Industry and enhance the FDA’s ability to fulfill its mission of protecting and promoting public health.
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: Eco-Life (URBAN REDEVELOPMENT following CATASTROPHE in nanjing, china): Yingqiu Wu_Master project_poster
Creator: Wu, Yingqiu
Date: 2011-05-04, 2011-05
Description: My project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The...
Show moreMy project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The project proposes a new urban plan to rebuild the neighborhood and restore the community. A powerful explosion at an abandoned plastics factory in Qixia district of Nanjing city has left several people dead and dozens injured. Buildings and vehicles within 100m of the factory destroyed, 3000 citizen got the key of the street and buildings suffered varying degrees of damage in the area 8 miles in circumference. The blast was caused by a leak from a gas pipeline inside the factory, the blast happened after workers dismantling the plant damaged a propylene pipeline. The leaked gas was then ignited when a car engine was started at the scene. There were a community college and several kindergartens in this area, fortunately, it was summer break at that time, no students hurt reported. It is a unique opportunity to develop a plan in an urban context when the prior years of development have been wiped away. The purpose of the project is giving condos return to 3000 people who lost their houses in the explosion and planing mix-used buildings of the community for next 20 years. At present, many old nerghbourhoods in China are being replaced by new ones. In the most cases, the existing urban patternes are erased and a town is built with out any links to what had previouly existed there. My ptoposal is reusing most of the existing tree line streets, river and bridges. The key of this proposal is sustainability, first idea is using existing river to develop a nice wetland park and the second idea is farming gradens.
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Ethics Statement
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Final Presentation
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Final Report_redacted
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Midterm Presentation
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Poster
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Project Plan_redacted
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: waterWORKS
Creator: Webster, Reed
Date: 5/3/2011, 2011-05
Description: Water shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United...
Show moreWater shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United States it will soon become our most valuable natural resource. In re-defining urban relationships to the Great Lakes a healthy, ecologically stable, and regenerative water system can become our greatest national asset. Providing a prototype solution for one of these urban areas (Traverse City, MI) may set a precedent for long term protection of the Great Lakes.
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Title: waterWORKS: RW_MastersBoardFinal
Creator: Webster, Reed
Date: 5/3/2011, 2011-05
Description: Water shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United...
Show moreWater shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United States it will soon become our most valuable natural resource. In re-defining urban relationships to the Great Lakes a healthy, ecologically stable, and regenerative water system can become our greatest national asset. Providing a prototype solution for one of these urban areas (Traverse City, MI) may set a precedent for long term protection of the Great Lakes.
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Title: waterWORKS: Reed Webster Final Book
Creator: Webster, Reed
Date: 5/3/2011, 2011-05
Description: Water shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United...
Show moreWater shortages will be a global problem by the year 2025. With the Great Lakes Basin accounting for 95% of the fresh water in the United States it will soon become our most valuable natural resource. In re-defining urban relationships to the Great Lakes a healthy, ecologically stable, and regenerative water system can become our greatest national asset. Providing a prototype solution for one of these urban areas (Traverse City, MI) may set a precedent for long term protection of the Great Lakes.
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Title: Discover. Action. Change.
Creator: Antea, Ruxandra
Date: 4/27/2011, 2011-05
Description: The project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover...
Show moreThe project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover. Action. Change. summarizes the intervention and the effect of this architectural project. The developed project wants to activate and change this deteriorate site into a place where people can came together and be aware of the new discoveries for green technologies and also can beneficiate of the outdoor space that incorporate lots of activities year-round. A bike and a pedestrian path are proposed to link two existent streets from the opposite neighborhoods and also to activate the site. The building, composed of two structures, is anchored along the path to reinforce it and also to create a reference point to everything ales on the site. The two proposed buildings represent a Research Center for Green Technologies with a training center and an Exhibit / Community space. These two structures are linked together through the RED TWIST element which guides the interested eye from the entrance at the south side, all the way to the North side. The twist serves as a floor for the first building and then chances and becomes the roof of the second building. In the end through all this elements implemented on the site, the project hopes to be a success for bringing people together into a pleasant environment, to an interesting / interactive building that allows visitors to be explored .
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Title: Discover. Action. Change.: Discover. Action. Change. Ruxandra Antea- May 2011
Creator: Antea, Ruxandra
Date: 4/27/2011, 2011-05
Description: The project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover...
Show moreThe project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover. Action. Change. summarizes the intervention and the effect of this architectural project. The developed project wants to activate and change this deteriorate site into a place where people can came together and be aware of the new discoveries for green technologies and also can beneficiate of the outdoor space that incorporate lots of activities year-round. A bike and a pedestrian path are proposed to link two existent streets from the opposite neighborhoods and also to activate the site. The building, composed of two structures, is anchored along the path to reinforce it and also to create a reference point to everything ales on the site. The two proposed buildings represent a Research Center for Green Technologies with a training center and an Exhibit / Community space. These two structures are linked together through the RED TWIST element which guides the interested eye from the entrance at the south side, all the way to the North side. The twist serves as a floor for the first building and then chances and becomes the roof of the second building. In the end through all this elements implemented on the site, the project hopes to be a success for bringing people together into a pleasant environment, to an interesting / interactive building that allows visitors to be explored .
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Title: Discover. Action. Change.: Discover.Action. Change. Poster- Ruxandra Antea- May 2011
Creator: Antea, Ruxandra
Date: 4/27/2011, 2011-05
Description: The project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover...
Show moreThe project is located in Chicago IL, between Bridgeport and Pilsen neighborhood, on an abandoned industrial site named Bubbly Creek. Discover. Action. Change. summarizes the intervention and the effect of this architectural project. The developed project wants to activate and change this deteriorate site into a place where people can came together and be aware of the new discoveries for green technologies and also can beneficiate of the outdoor space that incorporate lots of activities year-round. A bike and a pedestrian path are proposed to link two existent streets from the opposite neighborhoods and also to activate the site. The building, composed of two structures, is anchored along the path to reinforce it and also to create a reference point to everything ales on the site. The two proposed buildings represent a Research Center for Green Technologies with a training center and an Exhibit / Community space. These two structures are linked together through the RED TWIST element which guides the interested eye from the entrance at the south side, all the way to the North side. The twist serves as a floor for the first building and then chances and becomes the roof of the second building. In the end through all this elements implemented on the site, the project hopes to be a success for bringing people together into a pleasant environment, to an interesting / interactive building that allows visitors to be explored .
Show less

Title: Eco-Life (URBAN REDEVELOPMENT following CATASTROPHE in nanjing, china)
Creator: Wu, Yingqiu
Date: 2011-05-04, 2011-05
Description: My project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The...
Show moreMy project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The project proposes a new urban plan to rebuild the neighborhood and restore the community. A powerful explosion at an abandoned plastics factory in Qixia district of Nanjing city has left several people dead and dozens injured. Buildings and vehicles within 100m of the factory destroyed, 3000 citizen got the key of the street and buildings suffered varying degrees of damage in the area 8 miles in circumference. The blast was caused by a leak from a gas pipeline inside the factory, the blast happened after workers dismantling the plant damaged a propylene pipeline. The leaked gas was then ignited when a car engine was started at the scene. There were a community college and several kindergartens in this area, fortunately, it was summer break at that time, no students hurt reported. It is a unique opportunity to develop a plan in an urban context when the prior years of development have been wiped away. The purpose of the project is giving condos return to 3000 people who lost their houses in the explosion and planing mix-used buildings of the community for next 20 years. At present, many old nerghbourhoods in China are being replaced by new ones. In the most cases, the existing urban patternes are erased and a town is built with out any links to what had previouly existed there. My ptoposal is reusing most of the existing tree line streets, river and bridges. The key of this proposal is sustainability, first idea is using existing river to develop a nice wetland park and the second idea is farming gradens.
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Title: Eco-Life (URBAN REDEVELOPMENT following CATASTROPHE in nanjing, china): Yingqiu Wu_Master project_May 2011++
Creator: Wu, Yingqiu
Date: 2011-05-04, 2011-05
Description: My project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The...
Show moreMy project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The project proposes a new urban plan to rebuild the neighborhood and restore the community. A powerful explosion at an abandoned plastics factory in Qixia district of Nanjing city has left several people dead and dozens injured. Buildings and vehicles within 100m of the factory destroyed, 3000 citizen got the key of the street and buildings suffered varying degrees of damage in the area 8 miles in circumference. The blast was caused by a leak from a gas pipeline inside the factory, the blast happened after workers dismantling the plant damaged a propylene pipeline. The leaked gas was then ignited when a car engine was started at the scene. There were a community college and several kindergartens in this area, fortunately, it was summer break at that time, no students hurt reported. It is a unique opportunity to develop a plan in an urban context when the prior years of development have been wiped away. The purpose of the project is giving condos return to 3000 people who lost their houses in the explosion and planing mix-used buildings of the community for next 20 years. At present, many old nerghbourhoods in China are being replaced by new ones. In the most cases, the existing urban patternes are erased and a town is built with out any links to what had previouly existed there. My ptoposal is reusing most of the existing tree line streets, river and bridges. The key of this proposal is sustainability, first idea is using existing river to develop a nice wetland park and the second idea is farming gradens.
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Title: A NOVEL SWITCHED RELUCTANCE MOTOR BASED PROPULSION DRIVE FOR ELECTRIC AND PLUG-IN HYBRID ELECTRIC VEHICLES
Creator: Bilgin, Berker
Date: 2011-07, 2011-07
Description: Hybrid and Plug-in hybrid electric vehicles (HEVs and PHEVs) have received increasing attention from the automotive industry over the recent...
Show moreHybrid and Plug-in hybrid electric vehicles (HEVs and PHEVs) have received increasing attention from the automotive industry over the recent years. They are typically more efficient and they produce lower emissions than similar ICE-based vehicles, which significantly reduces their negative impact on the environment. In this study, design considerations of two fundamental parts of plug-in vehicles, traction motor and battery charger circuit, have been investigated toward the drivetrain applications in a solar assisted plug-in electric auto rickshaw. Switched reluctance motors (SRM) have been seen as potential candidates for propulsion systems over the last few years. They are robust, capable of performance in harsh operating conditions and have a wide speed range. Conventional SRM configurations have a higher number of stator poles than rotor poles. This PhD. dissertation presents the advantages of a novel SRM configuration with the number of rotor poles greater than number of stator poles and investigates the challenges in its design. Practical design considerations have been proposed and by using them a 3 phase 5 hp 6/10 SRM is designed, constructed and tested. A PHEV is a series or parallel hybrid electric vehicle equipped with a high energy density battery to extend the mileage and get better fuel efficiency. Since the capacity of the battery is higher than the sum of the energy that can be supplied by the internal combustion engine and regained from the regenerative braking, external charging from the grid is necessary. This research also investigates the requirements of the battery charger circuit and proposes low cost topology composed of a PWM boost rectifier cascaded with a bidirectional DC/DC converter. Operation of the circuit has been x xvii analyzed by deriving its mathematical model. Feedback controller requirements to control the input and output current and DC bus voltage have been studied. Critical issues to be considered in parameter selection of the voltage and current controller are explained in terms of universal input operation. In order to verify the analysis presented, an experimental hardware setup has been built and tested.
Ph.D. in Electrical Engineering, July 2011
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Title: IMPROVED METHODS FOR DETECTING PARTIALLY HYDROLYZED GLUTEN IN FOOD
Creator: Cao, Wanying
Date: 2016, 2016-07
Description: Celiac disease is an autoimmune disorder in susceptible individuals caused by the consumption of gluten, a class of storage proteins present...
Show moreCeliac disease is an autoimmune disorder in susceptible individuals caused by the consumption of gluten, a class of storage proteins present in wheat, barley and rye. There is no cure for celiac disease, and the only effective treatment is strict adherence to a gluten-free diet. Manufacturers who label their products as “gluten-free” must ensure that these products contain < 20 ppm gluten. Analytical methods currently exist for detecting and quantifying gluten in foods. However, quantifying gluten in fermented or hydrolyzed foods presents an analytical challenge. In order to develop reliable and accurate gluten analytical methods, a better understanding is needed with respect to gluten hydrolysis reactions that occur in fermented and hydrolyzed foods. In addition, research is needed to determine ways to control gluten in food production facilities that produce gluten-containing and gluten-free products on the same processing line. The objectives of this project were to: 1) evaluate the effectiveness of different cleaning procedures on removing gluten from a pilot-scale beer brewing line, 2) assess gluten cross-contact from a shared beer brewing line, 3) track the changes in gluten detection in traditionally brewed soy sauce at different stages of production using five commercial gluten ELISA kits and 4) evaluate the effects of an enzyme (a prolyl endopeptidase- Brewers Clarex®) on detecting gluten in beer brewed with barley malt as an ingredient. A pilot-plant scale beer brewing line located at the University of Wisconsin-Madison (UW-Madison) was used to produce sorghum beer (gluten-free beer), barley malt-containing beer and Clarex®-treated barley malt beer. Three cleaning methods (a push-through cleaning treatment, a hot water rinse, and a full cleaning procedure involving the use of an alkaline detergent) were evaluated for effectiveness at removing gluten residue from the pilot-scale brewing line at UW-Madison. Cleaning study results indicated that a hot water rinse and a push-through cleaning treatment with sorghum beer were less effective in removing gluten from equipment in the brewing line than a full cleaning procedure that included use of an alkaline detergent solution followed by a final hot water rinse. Gluten-free sorghum beer samples used to evaluate cross-contact from an inadequately cleaned brewing line were analyzed, and up to 105.1± 9.3 ppm (μg/mL) gluten was detected using the RIDA Competitive ELISA test kit which is designed to detect hydrolyzed gluten. Model soy sauce products were produced in a pilot-plant at Kikkoman R&D Center in Japan, and samples were obtained at different stages of production. Studies that traced gluten in soy sauce products found that high levels of gluten could be detected at the early stages of production prior to fermentation. However, gluten concentrations in soy sauces after fermentation were below the limit of quantitation (LOQ) for all of the gluten ELISA kits evaluated in the study. Use of Clarex® during the production of barley malt beer resulted in substantial reductions in the amount of gluten (intact and partially hydrolyzed) detected in beer compared to the control treatment without added enzyme. Although, gluten was detected at levels >20 ppm in some Clarex®-treated beer samples, filtration treatment further reduced gluten concentrations in these beer samples below 20 ppm gluten. Results of this project indicate that use of adequate cleaning procedures is needed to control gluten in food production facilities that have shared processing lines. Some fermentation and hydrolysis reactions that occur in food result in substantial reductions in gluten content as measured by ELISA. However, more work is needed to determine if celiac-reactive peptides still remain in these products.
M.S. in Food Safety and Technology, July 2016
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