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Title: Novel Chelating Agents for Positron Emission Tomography Imaging and Theranostic Applications
Creator: Zhang, Shuyuan
Date: 2022
Description: Positron emission tomography (PET) is a molecular imaging technology that can be used to detect various diseases including cancer. Zirconium...
Show morePositron emission tomography (PET) is a molecular imaging technology that can be used to detect various diseases including cancer. Zirconium-89 (t1/2 = 78.4 h) is one of the positron-emitting radionuclides that has been widely explored for PET imaging because its half-life matches the long biological half-life of antibody. Research efforts have been devoted to the development of chelation chemistry for 89Zr, a bone-seeking radionuclide. Deferoxamine (DFO) is the most frequently used chelator for 89Zr in both clinical and preclinical trials. DFO can rapidly sequester 89Zr to form 89Zr-DFO complex. However, DFO is not an ideal ligand for 89Zr because 89Zr-labeled DFO-antibody conjugate showed high bone uptake in mice. We wanted to develop novel small molecule donors and novel chelators for 89Zr. We discovered N-methyl-N-(pyridin-2-yl)hydroxylamine (Py-HA) and 2,6-bis(N-methylhydroxylamino)pyridine (Py-BHA) as small molecule donors for 89Zr. Based on the new small molecule donors (Py-HA and Py-BHA), we have designed and synthesized a series of novel macrocyclic chelators containing TACN (1,4,7-triazacyclononane), CYCLEN (1,4,7,10-tetraazacyclododecane), and a diaza-crown ether backbone for 89Zr-based PET imaging applications. Moreover, bifunctional chelators (BFCs) structured on TACN and diaza-18-crown-6 were synthesized for conjugation to antibody. Theranostics contains a diagnostic agent and a therapeutic drug that can be used for simultaneous therapy and imaging of diseases. Radiotheranostics includes radiometal complexes for both therapy and imaging. 177Lu is a promising radiotheranostic metal because it can emit gamma radiation for single photon emission computed tomography (SPECT) imaging and emit β radiation for radiotherapy. A radioisotope pair with complementary emission such as 64Cu/67Cu and 86Y/90Y, can be used for PET imaging and radiotherapy. In this study, we synthesized nonfunctional TACN and diaza crown ether-backboned chelators containing different donor groups for 177Lu, 64Cu/67Cu, and 86Y/90Y. Finally, two bifunctional chelators were synthesized for coupling with hydroxamic acid-based small molecule as a potential histone deacetylase (HDAC) inhibitor to generate a small molecule ligand-chelator conjugate (SMLC) for theranostic applications.
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Title: Improvement and Validation of Multiyear Auroral Analysis to Categorize Scintillation Event Layer
Creator: English, Breanna R.
Date: 2022
Description: Ionospheric irregularities scintillate electromagnetic waves, such as Global Positioning System (GPS) signals, as they pass through the...
Show moreIonospheric irregularities scintillate electromagnetic waves, such as Global Positioning System (GPS) signals, as they pass through the ionosphere, especially in auroral zones. A previous method was developed to determine which layer of the ionosphere these scintillation events occurred in by analyzing optical all sky images (ASI). The results of determining the ionospheric scattering layer using the ratio of 630 nm (red) intensity to 428 nm (blue) intensity were compared to a radar-based method of determining the scintillation layer, and it was found that the results disagreed. In this work, the ASI method is critically analyzed to identify possible errors or sensitivities in the original method that might resolve the discrepancy. This is done by improving and validating the nighttime auroral cloud detection method by comparing to National Oceanic and Atmospheric Administration (NOAA) satellite cloud data. Then a sensitivity analysis is performed on the ASI method to determine which parameters of the method the results are sensitive to. The keogram cloud detection method is improved by automating the selection of the keogram time points that are used to calculate a flat-field gain correction, and by calculating the flat field gain for each year rather than calculatingit once and using it for all years of the study. Keogram cloud detection using the coefficient of variation is verified by comparing the keogram results to true sky conditions based on NOAA cloud mask data, and using detection theory to determine the optimal coefficient of variation threshold. We find that the ideal keogram threshold was 0.37 producing a disagreement rate of 22.4%. The ASI image analysis criteria tested are: the ASI azimuth and elevation mapping files, the magnetic zenith limit, the number of pixels of the ASI that are being analyzed, the duration of the scintillation event that is analyzed, and the red-to-blue ratio threshold. It is found that only changing the red-to-blue ratio threshold has a significant effect on the ASI method, with the red-to-blue ratio that minimizes the number of misattributed layers found to be 1.43.
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Title: GLOBAL ESTIMATION AND ANALYSIS OF IONOSPHERIC DRIVERS WITH A DATA ASSIMILATION ALGORITHM
Creator: López Rubio, Aurora
Date: 2022
Description: This dissertation studies a data assimilation algorithm that estimates the drivers of the ionosphere-thermosphere (IT) region of the Earth....
Show moreThis dissertation studies a data assimilation algorithm that estimates the drivers of the ionosphere-thermosphere (IT) region of the Earth. The algorithm, EMPIRE (Estimating Model Parameters from Ionospheric Reverse Engineering) can estimate 2 main drivers of the ionospheric behavior: neutral winds and electric potential by ingesting mainly ionospheric densities obtained through Global Satellite System (GNSS) measurements. Additionally, the algorithm can ingest FPI (Fabry-Perot interferometer) neutral wind measurements. The contributions include 1) Vector spherical harmonic basis function for neutral wind estimation, 2) Quantification of the representation error of the estimations of the algorithm EMPIRE, 3) Analysis of Nighttime Ionospheric Localized density Enhancement (NILE) events and 4) Ingestion of global ICON (Ionospheric Connection Explorer) neutral winds measurements. The IT region in the atmosphere is characterized by having a large concentration of free ions and electrons, electromagnetic radiation and Earth's magnetic field. The behavior of the region is dominated by the solar activity, that ionizes the free electrons of the region, forming ionospheric plasma and determining its density. Unusual solar activity or any atmospheric disturbance affects the distribution of the ionospheric plasma and the behavior of the IT region. The redistribution of the ionospheric density impacts technology widely used such as telecommunication or satellite navigation, so it is increasingly important to study the IT system response. The IT behavior can be characterized by what drives its changes. Two drivers that play a key role, the ones we focus on this dissertation, are electric potential, that directly affects the charged ions in the system, and neutral winds, that refers to the velocity of the neutral particles that form the thermosphere. To quantify these drivers, measurements and climate models are available. Measurements are limited as the IT region is vast and covers the entire globe. Climate models can provide information in all the region, but they are usually not as reliable during the unusual solar activity conditions or disturbances. In this dissertation we use a data assimilation algorithm, EMPIRE, that combines both sources of data, measurements and models, to estimate the IT drivers, neutral winds and electric potential. EMPIRE ingests measurements of the plasma density rate and models the physics of the region with the ion continuity equation. The drivers are represented with basis functions and their coefficients are estimated by fitting the expansions with a Kalman filter. In previous work and use of the algorithm, the neutral winds were expanded using power series basis function for each of the components of the vector. The first contribution of the dissertation is to use a vector spherical harmonic expansion to describe the winds, allowing a continuous expansion around the globe and self-consistent components of the vector. Before, EMPIRE estimated the correction of the drivers with respect climate model values. In this work, EMPIRE is also modified to directly estimate the drivers. Then, a study of the representation error, which is the discrepancy between the true physics and the discrete model that represents the physics of EMPIRE and its quantification is done. Next, EMPIRE is used to analyze two NILE events, using the global estimation of both winds, from the first contribution, and the electric potential, derived in previous work. Finally, global estimation of winds allows us to implement the ingestion of ICON global winds in EMPIRE, in addition to the plasma density rate measurements.
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Title: PARENTAL RELATIONSHIP FACTORS, ACADEMIC EXPECTATIONS, AND MENTAL HEALTH OUTCOMES IN INDIVIDUALS WITH ADHD
Creator: Small, Eva E.
Date: 2022
Description: Individuals with Attention Deficit Hyperactivity Disorder (ADHD) are at a higher risk for developing comorbid psychological conditions...
Show moreIndividuals with Attention Deficit Hyperactivity Disorder (ADHD) are at a higher risk for developing comorbid psychological conditions including depression and anxiety by the time they reach adulthood. While there has been some research on potentially beneficial aspects of parent-child relationships that can help to improve the mental health of pediatric populations with ADHD, less work has been done to assess the long-term influence of the parent -child relationship in adults with ADHD. The purpose of this study was to add to previous research by utilizing the National Longitudinal Study of Adolescent to Adult Health (Add Health) to investigate how parenting relationship and family factors (i.e., parental warmth, behavioral autonomy, family cohesion, and parental academic expectations) predict symptoms of stress and depression in adults with ADHD. Using data from Waves I, III, and IV of the Add Health study, analyses examined whether positive parenting relationship factors were related to levels of depression symptoms and stress in a sample of participants with self-reported ADHD (N = 316). Results indicated that higher levels of family cohesion experienced in adolescence were associated with lower depression symptoms reported in adulthood, thus suggesting that family cohesion is a beneficial for individuals with ADHD. Future research should continue to examine the role that child-relationship factors can have on long term mental health outcomes in individuals with ADHD
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Title: Child and Family Outcomes Associated with Specific Maryland ASD Waiver Services and Choice and Control as Mediators of These Outcomes
Creator: Turchmanovych-Hienkel, Nataliya
Date: 2022
Description: Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects 1in 44 children and is characterized by impairments in cognitive...
Show moreAutism spectrum disorder (ASD) is a neurodevelopmental condition that affects 1in 44 children and is characterized by impairments in cognitive, behavioral, and social domains of functioning. Literature suggests that ASD not only impacts the quality of life of the individuals diagnosed with this condition, but also has a negative impact on family quality of life (FQoL). Interventions and services offered through the Medicaid 1915(c) Home and Community-Based Services waiver programs can enhance child and family outcomes. The present study looked at one specific waiver program, the Maryland ASD waiver, and examined the frequency at which families received different waiver services and the associations between those service frequencies and child (i.e., academic performance, independent living skills, social communication and interaction skills, stereotypic and repetitive behavior, and aggressive behavior) and family (i.e., FQoL) outcomes, as well as explored whether the family’s perception of choice and control mediate these child and family outcomes. Results suggest that frequencies of some waiver services are associated with progress in some child outcomes, but not in FQoL. This study also suggests that the choice and control that families have over services do not mediate the relation between frequency of waiver services and child and family outcomes. Overall, results suggest that the Maryland ASD waiver program may help improve some domains of child functioning.
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Title: DIAGNOSING AND TREATING ADHD: CLINICIAN CHARACTERISTICS, METHODS OF DIAGNOSIS, DIAGNOSTIC RATES, AND TREATMENT RECOMMENDATIONS
Creator: Haak, Christopher Luke
Date: 2019
Description: Attention-deficit/hyperactivity disorder (ADHD) is one of the top five most common referrals among all neuropsychologists (Sweet et al. 2015)...
Show moreAttention-deficit/hyperactivity disorder (ADHD) is one of the top five most common referrals among all neuropsychologists (Sweet et al. 2015) and continues to elicit public and professional concern about over-diagnosis in children (Sciutto & Eisenberg, 2007) and under-diagnosis in adults (Asheron et al., 2012; Kooji et al., 2010). In recent years, the prevalence of ADHD has increased (Polanczyk et al., 2007 & 2014, Thomas et al., 2015). It is unclear what is driving these changes though changes in criteria may be playing a role (van de Voort et al., 2014). Further, there has been little research on whether professional training, beliefs, and practice factors can influence the likelihood to diagnose ADHD. The purpose of this study was to examine the extent to which neuropsychologists’ professional characteristics, training, and beliefs about ADHD diagnosis and treatment influence their likelihood to diagnose ADHD. The study also evaluated whether there are differences in assessing and treating ADHD based upon the client population focus (child, lifespan, or adult) of neuropsychologists. Participants in this study were 106 neuropsychologists from across the United States and Canada who were recruited through neuropsychology listservs to participate in an online survey. Results indicated that population focus was associated with significant differences in approach to diagnosing and treating ADHD, with child- and lifespan-focused neuropsychologists reporting higher rates of ADHD diagnosis. Additionally, having a higher percent of clinical cases in which ADHD is a referral question and greater self-reported adherence to following full diagnostic criteria for making a diagnosis were associated with higher ADHD diagnostic rates, controlling for age, gender, ethnicity, and other professional characteristics. This study is among the first to examine specific clinician factors impacting diagnostic rates and its findings have several implications for practice and research.
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Title: High-latitude plasma drift structuring from a first principles ionospheric model
Creator: Kim, Heejin
Date: 2020
Description: In the high-latitude ionosphere dense plasma formations called polar cap patches are sometimes observed. These patches are often associated...
Show moreIn the high-latitude ionosphere dense plasma formations called polar cap patches are sometimes observed. These patches are often associated with ionospheric scintillation, a rapid fluctuation in the amplitude and phase of a radio signal that degrades communications and navigation systems. Predicting polar cap patch movement across the polar cap is an important subject for enabling forecasting of the scintillation.Lagrangian coherent structures (LCSs) are ridges indicating regions of maximum fluid separation in a time-varying flow. In previous studies, the Ionosphere-Thermosphere Algorithm for Lagrangian Coherent Structures (ITALCS) predicted the location of LCSs. These LCSs were shown to constrain polar cap patch source and transport regions for flow assumed to due to $\vec{E} \times \vec{B}$ plasma drift. The LCSs were predicted based on an empirical model of the high-latitude electric field for $\vec{E}$. In this thesis, the LCSs are generated using the first principles ionospheric model SAMI3 (SAMI3 is Another Model of the Ionosphere) as the model for electric field. The work relies on an understanding of various magnetic coordinate systems in space science, and includes three different approaches for attempting to generate the $\vec{E} \times \vec{B}$ drift as the flow fields that are to input to ITALCS. Finally, a representative LCS result is obtained with SAMI3 and shown to be at the high latitudes on the dayside, similar to prior work, but spanning a shorter longitudinal range.
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Title: The Development of a Measure of Public Stigma Towards Adults With Autism
Creator: Beedle, Robert Brian
Date: 2022
Description: Adults with autism (AwA) report experiences of stigma and discrimination. Yet, quantitative research suggests that public attitudes are...
Show moreAdults with autism (AwA) report experiences of stigma and discrimination. Yet, quantitative research suggests that public attitudes are relatively benign. This research discrepancy is compounded by the present lack of a stakeholder-informed, theoretically-guided measure of the stigma towards AwA. The objective of the present study was to develop a measure of stigma towards AwA following best practices survey methodology. First, existing related measures were reviewed for possible candidate items, yielding 36 draft questions related to the stigma of AwA. Next, seven stakeholders in the AwA community were recruited to provide feedback on their experiences of stigma and discrimination, as well as feedback on the draft items. Following stakeholder feedback, draft items were edited, added, or removed based on feedback from the participants with AwA and their lived experiences, resulting in a revised measure of 51 candidate items. Finally, these 51 items underwent a quantitative phase with participants recruited through MTurk (N = 357). Exploratory factor analyses were conducted in order to generate a data driven factor structure that reflected stigma theory. The end result was a 20-item, four factor solution measuring numerous components of stigma within factors including cognitive components of stigma, blame, positive and negative affect, and comfort with close contact. The resulting measurement tool was titled the Public Stigma towards Adults with Autism Scale (PSAWA) and demonstrated strong psychometric properties. The tool has utility for further studying stigma towards AwA and assessing stigma interventions.
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Title: Deep Learning Methods For Wireless Networks Optimization
Creator: Zhang, Shuai
Date: 2022
Description: The resurgence of deep learning techniques has brought forth fundamental changes to how hard problems could be solved. It used to be held that...
Show moreThe resurgence of deep learning techniques has brought forth fundamental changes to how hard problems could be solved. It used to be held that the solutions to complex wireless network problems require accurate mathematical modeling of the network operation, but now the success of deep learning has shown that a data-driven method could generate powerful and useful representations such that the problem could be solved efficiently with surprisingly competent performance. Network researchers have recognized this and started to capitalize on the learning methods’ prowess. But most works follow the existing black-box learning paradigms without much accommodation to the nature and essence of the underlying network problems. This thesis focuses on a particular type of classical problem: multiple commodity flow scheduling in an interference-limited environment. Though it does not permit efficient exact algorithms due to its NP-hard complexity, we use it as an entry point to demonstrate from three angles how the learning-based methods can help improve the network performance. In the first part, we leverage the graphical neural network (GNN) techniques and propose a two-stage topology-aware machine learning framework, which trains a graph embedding unit and a link usage prediction module jointly to discover links that are likely to be used in optimal scheduling. The second part of the thesis is an attempt to find a learning method that has a closer algorithmic affinity to the traditional DCG method. We make use of reinforcement learning to incrementally generate a better partial solution such that a high quality solution may be found in a more efficient manner. As the third part of the research, we revisit the MCF problem from a novel viewpoint: instead of leaning on the neural networks to directly generate the good solutions, we use them to associate the current problem instance with historical ones that are similar in structure. These matched instances’ solutions offer a highly useful starting point to allow efficient discovery of the new instance’s solution.
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Title: Promoting Healthy Lifestyle Behaviors for African Americans with Serious Mental Illness and Weight Concerns
Creator: Nieweglowski, Katherine
Date: 2022
Description: People with serious mental illness face greater rates of chronic illness and obesity compared to those without mental illness. These rates are...
Show morePeople with serious mental illness face greater rates of chronic illness and obesity compared to those without mental illness. These rates are disproportionately higher for those who are part of racially minoritized groups. For example, African Americans are more likely to be obese compared to their white counterparts. This study sought to test a diet and exercise program—developed through community-based participatory research—called “Behaviors for Healthy Lifestyles” (BHL) for African Americans with serious mental illness and weight concerns. The impact of this program, also combined with peer health navigation (PHN), was tested on various physical and mental health outcomes. Participants were randomly assigned to either integrated-care treatment as usual (IC-TAU), BHL, or BHL+PHN. Data was collected at baseline, 4-month, 8-month, and 12-month follow up for outcomes measuring general health, bodily pain, physical functioning, emotional well-being, depression, recovery, quality of life, weight efficacy, and emotional eating. Monthly data collection was also conducted on frequency of healthy lifestyle behaviors related to diet and physical activity. Findings from group by trial analyses of variance on these outcomes did not show any significant impact. Implications for testing diet and exercise interventions combined with PHN for this population are discussed along with future research considerations related to increasing attendance and participation for greater health improvements.
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Title: Stochastic dynamical systems with non-Gaussian and singular noises
Creator: Zhang, Qi
Date: 2022
Description: In order to describe stochastic fluctuations or random potentials arising from science and engineering, non-Gaussian or singular noises are...
Show moreIn order to describe stochastic fluctuations or random potentials arising from science and engineering, non-Gaussian or singular noises are introduced in stochastic dynamical systems. In this thesis we investigate stochastic differential equations with non-Gaussian Lévy noise, and the singular two-dimensional Anderson model equation with spatial white noise potential. This thesis consists of the following three main parts. In the first part, we establish a linear response theory for stochastic differential equations driven by an α-stable Lévy noise (1<α<2). We first prove the ergodic property of the stochastic differential equation and the regularity of the corresponding stationary Fokker-Planck equation. Then we establish the linear response theory. This result is a general fluctuation-dissipation relation between the response of the system to the external perturbations and the Lévy type fluctuations at a steady state.In the second part, we study the global well-posedness of the singular nonlinear parabolic Anderson model equation on a two-dimensional torus. This equation can be viewed as the nonlinear heat equation with a random potential. The method is based on paracontrolled distribution and renormalization. After splitting the original nonlinear parabolic Anderson model equation into two simpler equations, we prove the global existence by some a priori estimates and smooth approximations. Furthermore, we prove the uniqueness of the solution by classical energy estimates. This work improves the local well-posedness results in earlier works.In the third part, we investigate the variation problem associated with the elliptic Anderson model equation in a two-dimensional torus in the paracontrolled distribution framework. The energy functional in this variation problem is arising from the Anderson localization. We obtain the existence of minimizers by a direct method in the calculus of variations, and show that the Euler-Lagrange equation of the energy functional is an elliptic singular stochastic partial differential equation with the Anderson Hamiltonian. We further establish the L2 estimates and Schauder estimates for the minimizer as weak solution of the elliptic singular stochastic partial differential equation. Therefore, we uncover the natural connection between the variation problem and the singular stochastic partial differential equation in the paracontrolled distribution framework.Finally, we summarize our results and outline some research topics for future investigation.
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Title: Development of a Model To Investigate Inflammation Using Peripheral Blood Mononucleated Cells
Creator: Geevarghese Alex, Peter
Date: 2023
Description: Our modern culture in our society is facing one of the biggest risks in health which is high-calorie diet-related postprandial inflammation....
Show moreOur modern culture in our society is facing one of the biggest risks in health which is high-calorie diet-related postprandial inflammation. Chronic diseases may be caused if the energy-dense food is the choice meaning if it is uncontrolled, clinical studies have demonstrated this with the body's post-meal inflammatory response. We aimed to find the causes of postprandial inflammation in response to various dietary treatments and provide a model to demonstrate. We aimed to make use of in vivo and in vitro techniques and statistics to create a model. The created model would help us to design specific treatments to minimize inflammation with response to dietary. In addition to figuring out vital dietary additives, the model additionally facilitates the layout of individualized interventions to reduce inflammation, thereby improving long-time period health outcomes. We aim to understand the clinical observations of diet-induced postprandial inflammation on the molecular level. We desire to make contributions to reduce the impact of chronic inflammatory disorders that is associated with postprandial inflammation.
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Title: Quantifying the Sorption Behavior of Polypropylene Toward Methyl Salicylate and Phenylcyclohexane Under FDA Surrogate Testing Protocol for Recycled Plastics Use in Food Contact Materials
Creator: Senthilkumaran, Senthamizh Kumaran
Date: 2024
Description: The increasing use of recycled polypropylene in food packaging raises concerns about chemical migration. FDA’s surrogate testing protocol...
Show moreThe increasing use of recycled polypropylene in food packaging raises concerns about chemical migration. FDA’s surrogate testing protocol using hexane or heptane as a diluent has evaluated the efficiency of industrial recycling processes in removing contaminants from reclaimed polyethylene terephthalate (PET). Different conditions to optimize surrogate testing of polypropylene (PP) may be needed due to the different sorption behavior of PP relative to PET. This study examines how the interaction between the surrogate contaminant, diluting solvent, and polymer impacts the sorption of surrogate contaminants into PP. Methyl salicylate (MS) and phenylcyclohexane (PCH) were selected as surrogate contaminants based on the current FDA testing protocol and solubility parameters. Swelling and sorption experiments were performed at 40°C for up to 14 days on different types of PP (monophasic homopolymer polypropylene (h-PP), monophasic random copolymer (r-PP), and/or heterophasic block copolymer (heco-PP)) in n-hexane, 2-propanol, and ethanol as diluting solvents. Sorption of 1% (v/v) MS and PCH from each diluting solvent into h-PP was quantified by GC-MS. Results showed that the PP polymers in n-hexane swelled 10%-155% more than the alcohols. Both MS and PCH sorption in n-hexane required a much shorter time, approximately 12 h, to reach equilibrium in comparison to the alcohols, which required 2–10 days. The equilibrium sorption concentration of 1% MS into h-PP from n-hexane was 55% and 136% higher, respectively, compared to sorption of MS from 2-propanol and ethanol. On the other hand, the equilibrium sorption concentration of 1% PCH into h-PP from 2-propanol and ethanol was 11-12% higher compared to the sorption of MS from n-hexane. Our data indicates that solvent swelling cannot be overlooked when determining realistic initial contamination levels in PP. This research will assist the FDA in updating the Recycled Plastics Guidance for Industry and enhance the FDA’s ability to fulfill its mission of protecting and promoting public health.
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: Eco-Life (URBAN REDEVELOPMENT following CATASTROPHE in nanjing, china): Yingqiu Wu_Master project_poster
Creator: Wu, Yingqiu
Date: 2011-05-04, 2011-05
Description: My project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The...
Show moreMy project is an urban redevelopment following catastrophe. A catastrophic explosion in 2010 left a portion of Nanjing city destroyed. The project proposes a new urban plan to rebuild the neighborhood and restore the community. A powerful explosion at an abandoned plastics factory in Qixia district of Nanjing city has left several people dead and dozens injured. Buildings and vehicles within 100m of the factory destroyed, 3000 citizen got the key of the street and buildings suffered varying degrees of damage in the area 8 miles in circumference. The blast was caused by a leak from a gas pipeline inside the factory, the blast happened after workers dismantling the plant damaged a propylene pipeline. The leaked gas was then ignited when a car engine was started at the scene. There were a community college and several kindergartens in this area, fortunately, it was summer break at that time, no students hurt reported. It is a unique opportunity to develop a plan in an urban context when the prior years of development have been wiped away. The purpose of the project is giving condos return to 3000 people who lost their houses in the explosion and planing mix-used buildings of the community for next 20 years. At present, many old nerghbourhoods in China are being replaced by new ones. In the most cases, the existing urban patternes are erased and a town is built with out any links to what had previouly existed there. My ptoposal is reusing most of the existing tree line streets, river and bridges. The key of this proposal is sustainability, first idea is using existing river to develop a nice wetland park and the second idea is farming gradens.
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Ethics Statement
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Final Presentation
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Final Report_redacted
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Midterm Presentation
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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Title: IIT Creating Access to Remote Electronic Support (Summer 2011) IPRO 345: IIT Creating Access to Remote Electronic Support IPRO345 Summer2011 Poster
Creator: Kos, Carolyn, Valio, Nicole, Michael, Hazel, Chinzorig, Unubold, Johnson, Kendra
Date: 2011, 2011-07
Description: The purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project...
Show moreThe purpose of IPRO 345 is to improve and mobilize the data and remote health care system for Mount Sinai Hospital. Specifically, this project aims to create a data support to aid diabetic patients within 500 meters of the hospital in order to decrease cost of operation and time and increase the quality of care. We will develop the groundwork for future IPRO 345 teams that will eventually implement the new data collection program.
Sponsorship: Mount Sinai Hospital and Medical Center
Project Plan for IPRO 345: IIT Creating Access to Remote Electronic Support for the Summer 2011 semester
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