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- Title
- Developing Adaptive and Predictive Modules for the Second Generation of Multivariable Insulin Delivery System for People with Type-1 Diabetes
- Creator
- Askari, Mohammad Reza
- Date
- 2023
- Description
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In this research, we are developing the second generation of multivariable automated insulin delivery system (mvAID) for people with Type 1...
Show moreIn this research, we are developing the second generation of multivariable automated insulin delivery system (mvAID) for people with Type 1 diabetes (T1D). AID system is improved by integrating missing data from sensors into the system, reconciling outliers in the data, and eliminating the effects of artifacts in signals from wearable devices. Behavioral patterns of individuals with T1D are captured by data-driven models. The model predictive control algorithm of the mvAID uses these patterns for making decisions and predicting glucose concentrations in the future more accurately. A pipeline algorithm is developed for removing noise and motion artifacts from wristband signals. Then, energy expenditure, physical activity, and acute psychological stress (APS) are estimated from wearable device signals to detect and quantify disturbances affecting the concentration of blood glucose concentration. Additionally, different modules were designed for predicting risky glycemic episodes and are used to build the second generation of the mvAID system. The techniques developed are tested with historical data sets from various clinical experiments and free-living data, and with simulations made by using our multivariable glucose, insulin and physiological variables simulator (mGIPsim).
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- Title
- Transdiagnostic Emotional Factors as Mediators of the Relation between Obsessive-Compulsive Symptoms and Tobacco Use and Dependence in a Large Community Sample of Adolescents
- Creator
- Chang, Weilynn Christine
- Date
- 2023
- Description
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This study investigated the associations between obsessive compulsive disorder symptoms (OCS) and tobacco use and tobacco dependence in a...
Show moreThis study investigated the associations between obsessive compulsive disorder symptoms (OCS) and tobacco use and tobacco dependence in a large community sample of adolescents. Specifically, transdiagnostic emotional vulnerability factors (i.e., anhedonia, distress tolerance and anxiety sensitivity) were explored as potential mediators of the relation between OCS and tobacco use/dependence. Weighted logistic regression models found that OCS was significantly positively associated with likelihood of tobacco use in the past six months (when suppressor variables were excluded). Similarly, zero-inflated negative binomial regression models found a significant positive relation between OCS and tobacco dependence (when suppressor variables were excluded). There was no significant weighted indirect effect via anhedonia for the OCS-Tobacco Use association, which suggests that anhedonia was not a significant mediator in this case. However, the indirect effect via anhedonia for the OCS-Tobacco Dependence association was significant at the p < .05 level, but not the adjusted p < .001 threshold (when suppressor variables were removed). The weighted indirect effect via distress tolerance for the OCS-Tobacco Use association was significant at the p < .05 level, but not the p < .001 threshold (when suppressor variables were removed). There was no significant indirect effect via distress tolerance for the OCS-Tobacco Dependence association. There was a significant weighted indirect effect via anxiety sensitivity for the OCS-Tobacco Use association (when suppressor variables were removed). There were no significant indirect effects via anxiety sensitivity for the OCS-Tobacco Dependence association. When overlapping variance was accounted for by including all three mediators simultaneously, anhedonia was still not a significant mediator of the OCS-Tobacco Use association; there were still significant indirect effects via distress tolerance and anxiety sensitivity, under specific model parameters. Our results also revealed that while Asian adolescents demonstrated lower likelihood of tobacco use compared to those who were Hispanic/Latinae, Asian youth demonstrated more severe tobacco dependence symptoms.
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- Title
- Applications of Optimal Contract Theory in Brokerage
- Creator
- Alonso Alvarez, Guillermo
- Date
- 2023
- Description
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In this thesis we study optimal brokerage problems in different scenarios. The thesisis structured in two parts:...
Show moreIn this thesis we study optimal brokerage problems in different scenarios. The thesisis structured in two parts: In the first part of this thesis, corresponding to Chapter 2 and 3, we construct optimal brokerage contracts for multiple (heterogeneous) clients trading a single asset whose price follows the Almgren-Chriss model. The distinctive features of this work are as follows: (i) the reservation values of the clients are determined endogenously, and (ii) the broker is allowed to not offer a contract to some of the potential clients, thus choosing her portfolio of clients strategically. We find a computationally tractable characterization of the optimal portfolios of clients (up to a digital optimization problem, which can be solved efficiently if the number of potential clients is small) and conduct numerical experiments which illustrate how these portfolios, as well as the equilibrium profits of all market participants, depend on the price impact coefficients. In the second part of this thesis, corresponding to Chapter 4, we establish existence of a solution to the optimal contract problem in models where the state process is given by a multidimensional diffusion with linearly controlled drift. Then, under certain concavity assumptions, we show that the optimal contracts in the relaxed formulation also solve the associated strong optimal contract problem. The main advantages of this approach, relative to the existing methods, are due to the fact that it allows (i) to obtain the existence of an optimal contract (as a limit point of epsilon-optimal ones), and (ii) to include various additional constraints on the associated control problems (e.g., state constraints, difference in filtrations of the agent and of the principal, etc.). Finally, we apply our results to the problem of brokerage fees when the agent has access to a larger filtration.
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- Title
- The Peter Principle and Career Development in Construction Management
- Creator
- Bolisetty, Lakshmi Satya Bavya
- Date
- 2023
- Description
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The construction industry, like any other industry, may benefit from updating its working environment by adopting advances in technology,...
Show moreThe construction industry, like any other industry, may benefit from updating its working environment by adopting advances in technology, updating the qualifications of its workforce, and ensuring that the right professionals are employed at each level. Having effective career development programs, filling project management roles with competent professionals, and promoting competent professionals ensures a successful project delivery. Promotion typically ensures candidates are rewarded for their performance and motivates them towards achieving higher success. Promoting the wrong person or having an incompetent person at any management level has detrimental effects to the project’s success. However, according to the “Peter Principle” (Peter, 1969), incumbents in a hierarchy tend to rise to “a level of respective incompetence”. That is, they are promoted based on their success in their current role, rather than their ability to perform in the new one. Through a review of the literature and a critical analysis of the existing research, this study examines the strengths and weaknesses of the Peter Principle and its relevance to professionals employed by construction companies and construction management firms in contemporary management practice. It also explores the reasons why an incumbent is stuck in a position for a long time. The findings of this research suggest that while the Peter Principle may have some limitations, it remains an important concept for managers to consider when making decisions about employee promotion and development. It concludes that while the Peter Principle may have a significant effect in promotion decisions, there are also external circumstances unique to each individual that may affect their performance.
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- Title
- Qualitative Investigation of Stigma Experiences of Individuals Living with Hoarding Disorder
- Creator
- Bates, Sage
- Date
- 2023
- Description
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Hoarding disorder (HD) is characterized by significant difficulty discarding items, resulting in an accumulation of clutter. HD is a public...
Show moreHoarding disorder (HD) is characterized by significant difficulty discarding items, resulting in an accumulation of clutter. HD is a public health concern and is associated with treatment ambivalence (e.g., refusal to initiate treatment, dropout, and limited treatment compliance). While low insight and motivation may account for some of the treatment ambivalence, it also could be due to a number of other factors related to how HD is being perceived by others, such as stigma. Yet, there is very little research on the relationship between stigma and hoarding, and what these studies have shown is that HD is judged negatively by the general population (i.e., public stigma) in a variety of ways. However, despite these initial findings, there are no in-depth studies examining stigma of HD from the perspective of those with lived experience. Further, previous research of stigma and HD utilized stigma measures that were significantly modified from their original intent to measure severe mental illness, and it is possible that general measures of stigma may not capture the specific features of HD or public perceptions of HD. The present study is a qualitative analysis to investigate stigma pertinent to HD.
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- Title
- Organo-Functionalized Polyoxometalates
- Creator
- Alsaleh, Musaed Riyadh A
- Date
- 2023
- Description
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Polyoxometalates (POM) or transition metal oxide clusters are a sub-class of metal oxide-based materials of contemporary interest. POMs are...
Show morePolyoxometalates (POM) or transition metal oxide clusters are a sub-class of metal oxide-based materials of contemporary interest. POMs are molecular systems which contain highly symmetrical structures and are characteristics of group 5 and 6 metals, especially V, Mo, and W. Typical POM clusters have nuclearities ranging from 6 to 18 metal centers and are purely inorganic in their compositions. POMs can act as multielectron redox systems, while retaining their robust oxometallic framework structure. POMs have been receiving increasing attention, in part due to their potential as redox active materials for applications in various areas and their suitability as attractive molecular building units for making new functional materials of desirable properties and functions.In recent years, there has been a growing interest in the functionalization of polyoxometalates with organic moieties to synthesize organo-functionalized POMs. During the course of the work described in this thesis, we explored the synthesis of organo-functionalized polyoxometalates with special interest in polyoxovanadates incorporating heterometal center(s) in addition to vanadium in the structure. The focus of the work was on low nuclearity POMs. The thesis describes the synthesis and full characterization of a new organo-functionalized polyoxovanadate cluster - [(n-C4H9)4N]2[V6O13{(OCH2)3C (CH2CH3)}2]. The cluster compound has been characterized by a series of analytical techniques- FT-IR, Thermo Gravimetric Analysis, Bond Valence Sum calculations and complete single X-ray diffraction structure analysis. The hexavanadate cluster features {V6O19} oxometallate core composed of six edge sharing {VO6} octahedra defined by five bridging oxygen atoms and a terminal {V=Ot} oxo group. The {V6O19} oxometallic core of the cluster adopts the Lindqvist structure incorporating two 1,1,1-tris(hydroxymethyl)propane organic ligands. Six of the oxygens in the {V6O19} core come from the three alkoxy groups from two organic ligands. To the best of our knowledge, this organo-functionalized POM cluster has not been reported in the literature previously.
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- Title
- Efficacy of Power Ultrasound Technology on the Reduction of Listeria monocytogenes and Salmonella enterica on Produce Matrices
- Creator
- Biswas, Priya
- Date
- 2023
- Description
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Fresh produces are considered as ready-to-eat (RTE) and are minimally processed before the distribution to retailers and consumers. Fresh...
Show moreFresh produces are considered as ready-to-eat (RTE) and are minimally processed before the distribution to retailers and consumers. Fresh produce recalls are frequently linked with pathogenic bacteria like Salmonella enterica and Listeria monocytogenes because of minimal processing. This study evaluated the use of power ultrasound coupled with organic acids like citric, acetic, and lactic acid which are generally recognized as safe and often helps to maintain the quality and prolong the shelf life of fresh RTE fruits and vegetables.All the produce matrices which include cucumbers, romaine lettuce, tomatoes, and strawberry were inoculated with four-strain cocktails of rifampicin-resistant S. enterica or L. monocytogenes at approximately 8 log CFU/ matrix. The produce matrices were dried for 1 h and treated for 2 minutes using 2 % or 5 % citric, lactic, or malic acid. This treatment was conducted with or without power ultrasound treatment at 40 kHz. Samples were taken in sets of three and placed into a stomacher bags. The bag contained 225 ml of water or acid. Following a 2 min treatment period, the samples were placed in separate stomacher bags, each containing 225ml of BPB or BLEB, for S. enterica or L. monocytogenes respectively. Followed serial dilutions, samples were then plated on BHIARif plates. For each condition, triplicate samples were taken, and three separate trials were conducted. The use of Student's t-test allowed for the evaluation of population differences, with a significance level of p<0.05 being deemed significant. Cucumber, romaine lettuce, tomatoes, and strawberries treated with 5 % concentration of citric, lactic, and malic acids, with addition of ultrasound showed a greater result in reductions of S. enterica to populations of 5.54 ± 0.47, 4.54 ± 0.83, and 4.69 ± x 0.36, log CFU/cucumber, 6.66 ± 0.51, 4.12 ± 0.32, and 5.51 ± 0.68, log CFU/ lettuce, 4.38 ± 0. 47, 3.12, and 5.04 ± 0.37 log CFU/ tomato, 4.66 ± 0.49, 4.69 ± 0.06, and 6.22 ± 0.39, log CFU/ strawberries, respectively. For L. monocytogenes, 5 % concentration of acids with the addition of ultrasound resulted in populations of 7.69 ± 0.35, 6.04 ± 0.24, and 6.96 ± 0.41, log CFU/ cucumbers, 7.57 ± 0.12, 5.49 ± 0.55, and 5.78 ± 0.73 log CFU/ lettuce, 6.44 ± 0.13, 5.08 ± 0.12, and 6.04 ± 0.22 log CFU/ tomato, 6.16 ± 0.37, 5.18 ± 0.22, and 5.64 ± 0.50, log CFU/ strawberries, respectively. The most effective acid was lactic when compared with citric and malic acids. The objective of this study is to investigate the effectiveness of power ultrasound as a novel non-thermal processing technology, in order to contribute to the existing knowledge base on this topic.
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- Title
- Critical Understanding of Multi-Mode Luminescence Properties of Eu3+ Doped LaAlO3
- Creator
- Alolayan, Abdulelah Abdulaziz H
- Date
- 2023
- Description
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Fluorescent anti-counterfeit materials with multi-luminescent modes under different external excitation sources are always advantageous over...
Show moreFluorescent anti-counterfeit materials with multi-luminescent modes under different external excitation sources are always advantageous over the conventional anti-counterfeit techniques. In the present thesis, our aim is to develop efficient Eu3+ doped LaAlO3 phosphor materials with different modes of luminescence properties such as down conversion-luminescence (DCL), persistent-luminescence (PersL), and optically stimulated luminescence (OSL), Thermo-luminescence (TL), radioluminescence (RL) Although, there are many reports on persistent-luminescence and optically stimulated luminescence based on Eu3+ doped matrices but the red persistent luminescence of Eu3+ ion on those matrices is not very long and the OSL intensities are also low. Herein, we report a long red persistent luminescence which lasted for 17 hrs. and the OSL intensity is very high. Furthermore, we have observed that the OSL property can be achieved even after 35 days of UV excitation and indicating its potential application for optical storage phosphor. From carrying out TSL studies we have found that three different types of traps namely Trap 1, Trap 2 and Trap 3 with trap depth 0.63 eV, 0.82 eV, 1.02 eV respectively are responsible for the persistent and OSL properties. It has been concluded that Trap 1 is mostly responsible for the persistent luminescence in short term while Trap 2 and Trap 3 are responsible for intermediate and long persistent luminescence. Further, Trap 2 and Trap 3 were also found to be present even after 35 days and responsible for the OSL properties. Anti-counterfeiting PersL composite has been developed in which AC real-life application is demonstrated.
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- Title
- Towards Utility-Driven Data Analytics with Differential Privacy
- Creator
- Wang, Han
- Date
- 2023
- Description
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The widespread use of personal devices and dedicated recording facilities has led to the generation of massive amounts of personal information...
Show moreThe widespread use of personal devices and dedicated recording facilities has led to the generation of massive amounts of personal information or data. Some of them are high-dimensional and unstructured data, such as video and location data. Analyzing these data can provide significant benefits in real-world scenarios, such as videos for monitoring and location data for traffic analysis. However, while providing benefits, these complicated data always raise serious privacy concerns since all of them involve personal information. To address privacy issues, existing privacy protection methods often fail to provide adequate utility in practical applications due to the complexity of high-dimensional and unstructured data. For example, most video sanitization techniques merely obscure the video by detecting and blurring sensitive regions, such as faces, vehicle plates, locations, and timestamps. Unfortunately, privacy breaches in blurred videos cannot be effectively contained, especially against unknown background knowledge. In this thesis, we propose three different differentially private frameworks to preserve the utility of video and location data (both are high-dimensional and unstructured data) while meeting the privacy requirements, under different well-known privacy settings. Specifically, to our best knowledge, wepropose the first differentially private video analytics platform (VideoDP) which flexibly supports different video queries or query-based analyze with a rigorous privacy guarantee. Given the input video, VideoDP randomly generates a utility-driven private video in which adding or removing any sensitive visual element (e.g., human, and object) does not significantly affect the output video. Then, different video analyses requested by untrusted video analysts can be flexibly performed over the sanitized video with differential privacy. Secondly, we define a novel privacy notion ϵ-Object Indistinguishability for all the predefined sensitive objects (e.g., humans, vehicles) in the video, and then propose a video sanitization technique VERRO that randomly generates utility-driven synthetic videos with indistinguishable objects. Therefore, all the objects can be well protected in the generated utility-driven synthetic videos which can be disclosed to any untrusted video recipient. Third, we propose the first strict local differential privacy (LDP) framework for location-based service (LBS) (“L-SRR”) to privately collect and analyze user locations or trajectories with ε-LDP guarantees. Specifically, we design a novel LDP mechanism “staircase randomized response” (SRR) and extend the empirical estimation to further boost the utility for a diverse set of LBS Apps (e.g., traffic density estimation, k nearest neighbors search, origin-destination analysis, and traffic-aware GPS navigation). Finally, we conduct experiments on real videos and location dataset, and the experimental results demonstrate all frameworks can have good performance.
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- Title
- Latent Price Model for Market Microstructure: Estimation and Simulation
- Creator
- Yin, Yuan
- Date
- 2023
- Description
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This thesis focuses on exploring and solving several problems based on partiallyobserved diffusion models. The thesis has two parts....
Show moreThis thesis focuses on exploring and solving several problems based on partiallyobserved diffusion models. The thesis has two parts. In the first part we present a tractable sufficient condition for the consistency of maximum likelihood estimators (MLEs) in partially observed diffusion models, stated in terms of stationary distributions of the associated test processes, under the assumption that the set of unknown parameter values is finite. We illustrate the tractability of this sufficient condition by verifying it in the context of a latent price model of market microstructure. Finally, we describe an algorithm for computing MLEs in partially observed diffusion models and test it on historical data to estimate the parameters of the latent price model. In the second part we provide a thorough analysis of the particle filtering algorithm for estimating the conditional distribution in partially observed diffusion models. Specifically, we focus on estimating the distribution of unobserved processes using observed data. The algorithm involves several steps and assumptions, which are described in detail. We also examine the convergence of the algorithm and identify the sufficient conditions under which it converges. Finally, we derive an explicit upper bound of the convergence rate of the algorithm, which depends on the set of parameters and the choice of time frequency. This bound provides a measure of the algorithm’s performance and can be used to optimize its parameters to achieve faster convergence.
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- Title
- Electric Machine Windings with Reduced Space Harmonic Content
- Creator
- Tang, Nanjun
- Date
- 2023
- Description
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The reduction of magnetomotive force (MMF) space harmonic content in electric machine windings can significantly improve the machine's...
Show moreThe reduction of magnetomotive force (MMF) space harmonic content in electric machine windings can significantly improve the machine's electromagnetic performance. Potential benefits include a reduction of torque ripple, a more sinusoidal back EMF, and reduced power losses. With the proposal of a uniform mathematical representation that applies to both distributed windings and fractional-slot concentrated windings (FSCWs), closed-form expressions can be derived for harmonic magnitudes, winding factors, etc. These expressions can then be used to formulate the MMF space harmonic suppression problem for windings, which looks for improved windings with certain harmonic orders reduced or even eliminated, by varying the slot distribution and coil turns. Different solution techniques are explored to gain additional insights about the solution space. The underlying mathematical relations between different harmonic orders are mathematically proved to establish the family phenomenon, which presents clear pictures of the higher order part of the harmonic spectrum and is the foundation for exact calculation of the total harmonic distortion (THD) of windings. The exact THD calculation further indicates how the minimal THD can be achieved for a winding. Windings can also be analyzed and designed from the view of subsets to incorporate distribution and excitation phase shift effects. With reduced or the minimal space harmonic content, new winding designs can help significantly improve the Pareto front when combined with motor geometry optimization. Design examples including a 12-slot 2-pole mixed-layer distributed winding, a 18-slot 2-pole mixed-layer distributed winding, and a four-layer 24-slot 22-pole FSCW with excitation phase shift are presented with finite element analysis (FEA) results to verify the performance improvements.
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- Title
- Polarization Induced by A Terahertz Electric Field in A Semiconductor Nanodimer in the Overlapping Regime
- Creator
- Wang, Zi
- Date
- 2023
- Description
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Boltzmann transport equation is a theoretical framework for the description of thermodynamics or charge reactions in a system not in...
Show moreBoltzmann transport equation is a theoretical framework for the description of thermodynamics or charge reactions in a system not in equilibrium, which can be applied to the analysis of the interactions of mobile charges with an electromagnetic wave. When the dimensions of the object are small compared to the wavelength, the induced dipole moment provides a means to characterize the collective response while providing insight to the nature of the charge-field interactions. Semiconductor nanoparticles exhibit surface plasmon resonance in the terahertz frequency range and are of current interest for the development of components and circuits in that part of the electromagnetic spectrum. By changing the plasmon frequencies of doped semiconductors through the change of carrier concentration, new opportunities arise for plasmonic manipulation in terahertz region leading to various promising applications. Despite the Drude model's long-term success and convenience in describing the electrical conductivity of metals in terms of dielectric functions, some aspects of polarization are not accounted for by bulk properties. By incorporating the transport equations of the charge carriers with Maxwell's equations, screening effects of charge carriers can be accounted for, enabling the internal field, space charge and induced dipole moment of a semiconductor nanoparticle to be studied.The computations performed for elementary dimer structures in overlapping cases revealed the internal field screening, while the complex dipole moments show dispersion and absorption effects. The numerical algorithms are implemented using the finite element method to investigate the surface plasmon resonance (SPR) induced on the semiconductor particles. Unique SPR modes evolution is observed as the thickness of the overlap region is varied. The characteristics can be interpreted by the migration of local space charge as the level of overlap is varied. This degree of freedom provided by a semiconductor nanodimer could be employed to control the local field near a simple cluster of nanoparticles, with potential for application in sensing and circuit components in the terahertz frequency range.
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- Title
- High Frequency Trading and the Impact of Volume-Duration on Market Quality in the U.S. Futures Markets
- Creator
- Xu, Xiaoruo
- Date
- 2023
- Description
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This paper examines the impact of High Frequency Trading (HFT) on market quality in the U.S. futures market through the lens of Adjusted...
Show moreThis paper examines the impact of High Frequency Trading (HFT) on market quality in the U.S. futures market through the lens of Adjusted Volume-Durations (AVD). By using the unique nanosecond level TAQ CME datasets of commodities futures in 2018, which include Crude Oil, E-mini S&P 500, Eurodollar, Gold, Corn and Soybean, I create the AVDs of each dataset, then conduct the regression analysis on market quality variables with the independent variables including AVDs and other key variables, and the results show that as AVD decreases, the market quality deteriorates, thus HFT positively affects market quality in the U.S. futures market. In order to explore the main driver of AVD on market quality in the futures market, I use the Autoregressive Conditional Duration Model to decompose AVDs into expected AVDs (AEVD), which is the component of AVD that is influenced by past AVDs and unexpected AVDs (AUVD), which is the component of AVD that is not captured by past AVDs but by unanticipated events, and then conduct the regression analysis on market quality variables with the independent variables including AEVD, AUVD and other key variables. The result shows that AEVD has a higher impact on liquidity than AUVD, but the impact of AEVD and AUVD on volatility is mixed in the U.S. futures market. However, except for the conclusions get from the based multivariate regression results, I also explain why there are some outliers for the Eurodollar, soybean and gold, and why HFT has more explicit impact on agricultural futures market.
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- Title
- Neuropsychological Pattern of Verbal and Nonverbal Processing Speed Discrepancy in Veterans with Co-Occurring mTBI and PTSD
- Creator
- VanLandingham, Hannah B.
- Date
- 2023
- Description
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Rates of traumatic brain injury (TBI) exposure have increased over time (CDC, 2022). This pattern of increased TBI risk is additionally...
Show moreRates of traumatic brain injury (TBI) exposure have increased over time (CDC, 2022). This pattern of increased TBI risk is additionally associated with risk for development of posttraumatic stress disorder (PTSD; APA, 2013). Ongoing PTSD symptomology can lead to neuropsychological profiles in which deficits are more pronounced for verbally constrained performances when compared to nonverbal performances. However, less is known about this performance discrepancy in patients with a history of head injury with comorbid PTSD. Moreover, the little existing research focuses on the domains of executive functioning, learning, and memory, with little to no research on processing speed discrepancies. These findings could have significant implications for healthcare and cognitive intervention pre- and post-mTBI and/or trauma exposure because this discrepancy may impact clinical assessment and subsequent diagnosis. The analysis will include 1) determination of statistically and clinically significant differences for those with co-occurring PTSD and mTBI, and 2) examine within-subjects differences with and without the inclusion of covariates. The present research found that there are no differences between those with co-occurring PTSD and head injury compared to individuals without a co-occurring diagnosis, in addition to no significant discrepancies notes within the PTSD and mTBI group alone
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- Title
- Phase field modeling and computation of vesicle growth or shrinkage
- Creator
- Tang, Xiaoxia
- Date
- 2023
- Description
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Lipid bilayers are the basic structural component of all biological cell membranes. It is a semipermeable barrier to most solutes, including...
Show moreLipid bilayers are the basic structural component of all biological cell membranes. It is a semipermeable barrier to most solutes, including ions, glucoses, proteins and other molecules. Vesicles formed by a bilayer lipid membrane are often used as a model system for studying fundamental physics underlying complicated biological systems such as cells and microcapsules. Mathematical modeling of membrane deformation has become an important topic in biological and industrial system for a long time. In this thesis, we develop a phase field model for vesicle growth or shrinkage based on osmotic pressure that arises due to a chemical potential gradient. This thesis consists of three main parts.In the first part, we establish a phase field model for vesicle growth or shrinkage without flow. It consists of an Allen-Cahn equation, which describes the evolution of the phase field parameter (the shape of the vesicle), and a Cahn-Hilliard-type equation, which simulates the evolution of the ionic fluid. The model is mass conserved and surface area constrained during the membrane deformation. Conditions for vesicle growth or shrinkage are analyzed via the common tangent construction. We develop the numerical computing in two-dimensional space using a nonlinear multigrid method which is a combination of nonlinear Gauss-Seidel relaxation operator and V-cycles multigrid solver, and perform convergence tests that suggest an $\mathcal{O}(t+h^2)$ accuracy. Numerical results demonstrate the growth and shrinkage effects graphically and numerically, which agree with the conditions analyzed via the common tangent construction.In the second part, we present a model for vesicle growth or shrinkage with flow. The dynamical equations considered are an Allen-Cahn equation, which describes the phase field evolution, a Cahn-Hilliard-type equation, which simulates the fluid concentration, and a Stokes-type equation, which models the flow. The numerical scheme in two-dimensional space includes a nonlinear multigrid method comprised of a standard FAS method for the Allen-Cahn and Cahn-Hilliard part, and the Vanka smoothing strategy for the Stokes part. Convergence tests imply an $\mathcal{O}(t+h^2)$ accuracy. Numerical results are demonstrated under zero velocity boundary condition and with boundary-driven shear flows, respectively.In the last part, we give an unconditionally energy stable and uniquely solvable finite difference scheme for the model established in the first part. The finite difference scheme is based on a convex splitting of the discrete energy and is semi-implicit. One key difficulty associated with the energy stability is due to the fact that some nonlinear energy functional terms in the expansion is neither convex nor concave. To overcome this subtle difficulty, we add auxiliary terms to make the combined term convex, which in turn yields a convex–concave decomposition of the physical energy. As a result, both the unique solvability and energy stability of the proposed numerical scheme are assured. In addition, we show the scheme is stable in the defined discrete norm.
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- Title
- Leader Identity Claiming and Granting Process: The Role of Gender on Perceptions of Leadership
- Creator
- Standish, Melanie P.
- Date
- 2023
- Description
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Ely, Ibarra, and Kolb (2011) theorize that the leader identity work among women is an area of work wherein subtle gender bias is pervasive and...
Show moreEly, Ibarra, and Kolb (2011) theorize that the leader identity work among women is an area of work wherein subtle gender bias is pervasive and impacting women’s advancement in the workplace. Interferences with the leader identity development process not only impact how a woman views herself as a leader, but how others collectively come to endorse her as a leader. Simply observing an individual claiming leadership and having that leadership be granted by someone else is known to influence how an observer classifies an individual as a leader or a non-leader. This study examines how the gender of an individual claiming leadership impacts external perceptions of how leader-like they are to others, when they are granted vs. not granted leadership. To examine this gap, this study uses an experimental vignette methodology to explore the impact of gender on leadership perceptions, during a claiming and granting process. Specifically, this work examines the mediating roles of competence and likability, as potential drivers through which differences may occur. Though women today are evaluated as equally competent as their male counterparts, engaging in dominant, agentic, behaviors, may make them less likable, and rated less leader-like as a result. The results of this study did not find an interaction between gender and granting, on perceived likability. The results did replicate existing findings that claiming leadership is not enough to be relationally recognized as a leader, and that granting from others plays an important role in how competent, and subsequently leader-like, an individual is perceived to be.
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- Title
- Approximation Algorithms for Selected Network and Graph Problems
- Creator
- Wang, Xiaolang
- Date
- 2023
- Description
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This dissertation proposes new polynomial-time approximation algorithms for selected optimization problems, including network and classic...
Show moreThis dissertation proposes new polynomial-time approximation algorithms for selected optimization problems, including network and classic graph problems. We employed distinct strategies and techniques to solve these problems. In Chapter 1, we consider a problem we term FCSA, which aims to find an optimum way how clients are assigned to servers such that the largest latency on an interactivity path between two clients (client 1 to server 1, server 1 to server 2, then server 2 to client 2) is minimized. We present a (3/2)-approximation algorithm for FCSA and a (3/2)-approximation algorithm when server capacity constraints are considered. In Chapter 2, we focus on two variants of the Steiner Tree Problem and present better approximation ratios using known algorithms. For the Steiner Tree with minimum number of Steiner points and bounded edge length problem, we provide a polynomial time algorithm with ratio 2.277. For the Steiner Tree in quasi-bipartite graphs, we improve the best-known approximation ratio to 298/245 . In Chapter 3, we address the problem of searching for a maximum weighted series-parallel subgraph in a given graph, and present a (1/2 + 1/60)-approximation for this problem. Although there is currently no known real-life application of this problem, it remains an important and challenging open question in the field.
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- Title
- Research through Provocation: A Structured Process to Design New Information Technologies
- Creator
- Rivera Gomez, Jaime Alejandro
- Date
- 2023
- Description
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This doctoral research presents a structured way to generate provocative prototypes, called provotypes, to design new information technologies...
Show moreThis doctoral research presents a structured way to generate provocative prototypes, called provotypes, to design new information technologies. Emphasizing the exploration of alternative interaction models beyond the current archetypes, this study considers emerging complexities about our relationship with technology in the long term to incorporate knowledge from science models in the early stages of the project when cross-disciplinary consensus is required. Thus, avoiding personal biases that are not aligned with how people use technology.The methodology analyzes six case studies using provotypes in multiple contexts, including academic research explorations, corporate innovation projects, and students applying the approach in educational settings. The research also involved a controlled experiment studying how different interactive configurations influence one's motivation to engage in positive behavior change. The results can be summarized in three main contributions: A provocation model to influence the shared meaning inside cross-functional teams, a tool to create provocations exploring alternative interaction models, and finally, the heuristics of provotyping to guide researchers and designers to generate early low fidelity prototyping.
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- Title
- Two Essays on Corporate Finance and Fixed-income Securities
- Creator
- Shen, Hao
- Date
- 2023
- Description
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In this study, we empirically investigate the relation between corporate finance and fixed income securities. Specifically, we employ...
Show moreIn this study, we empirically investigate the relation between corporate finance and fixed income securities. Specifically, we employ staggered changes in state corporate income tax rates as exogenous shocks and estimate how these state tax changes affect bond at-issue yield spreads. We find a significant increase in bond yield spreads after state tax increases but not after state tax decrease. Tax increases result in a 36 basis points increase in the yield spreads, which translates into a $12 million increase in interest expenses for firms experiencing tax increases. Besides, we employ the staggered adoption of universal demand (UD) laws by different states in the United States as a quasi-experimental setting and investigate the effect of UD laws on bond yield spreads at issuance. The adoption of UD laws raises the hurdle for shareholders to bring derivate lawsuits against firms and weakens shareholder litigation rights. Using a sample of bond issuances from 1985 to 2009, we find that the adoption of UD laws is positively associated with yield spreads of bonds issued by U.S. firms.
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- Title
- Melt Growth of Indium-Iodide on Earth and in Microgravity
- Creator
- Riabov, Vladimir
- Date
- 2023
- Description
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Indium Iodide is a heavy metal halide and a wide band-gap semiconductor which has a potential for application in room temperature γ- and X-ray...
Show moreIndium Iodide is a heavy metal halide and a wide band-gap semiconductor which has a potential for application in room temperature γ- and X-ray detectors. Its physical properties are similar to those of other materials used as room temperature radiation detectors. Over the years the technology of purification and crystal growth of InI was developed. Significant advances were made to improve purity, crystal structure and resulting electronic properties of the material. Nevertheless, the desired detector performance has not been achieved yet. Stress-induced crystal lattice defects resulting from solidification in contact with crucible are suspected to be responsible for the limited performance. Microgravity environment was previously used to study its effects on the process of crystal growth from the melt applied to semiconductors. It was observed that unlike on Earth materials can solidify without contact with the wall, when the sample is confined by the crucible. It was also shown that such detached solidification can drastically reduce stress-induced defects of the crystal lattice and improve electronic properties of the material. In this study crystal growth of InI was studied in microgravity, attempting to achieve detached solidification, and observe it in a transparent zone of a furnace. Partially detached solidification (a large free surface) has occurred in one of the samples. The resulting crystals were characterized by measuring their electronic properties and estimating the radiation detector performance of the devices manufactured using the crystals.
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