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Title: UNISERVO VIII-C tape drives and UNIVAC 1108/II computer, Illinois Institute of Technology, Chicago, Illinois, ca. 1969
Date: 1969
Description: Photograph of a man working on UNIVAC UNISERVO VIII-C tape drives and UNIVAC 1108 Model II computer in the Computer Science Building (3201 S....
Show morePhotograph of a man working on UNIVAC UNISERVO VIII-C tape drives and UNIVAC 1108 Model II computer in the Computer Science Building (3201 S. Michigan). The UNIVAC 1108/II was one of the most powerful computers in Illinois at the time of its installation, and it replaced the IBM 360/75 located in the Commons basement. Photographer unknown, possibly Dan Ryan. Date of photograph is unknown. Date listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Two Men with A-C Network Calculator, Illinois Institute of Technology, ca. 1951
Date: 1951
Description: Photograph of two men (possibly W.C Jacobs and J. M. Brager of Consumers Power Company using Illinois Institute of Technology's A-C Network...
Show morePhotograph of two men (possibly W.C Jacobs and J. M. Brager of Consumers Power Company using Illinois Institute of Technology's A-C Network Calculator. The A-C Calculator, used to test complex power systems in a controlled, miniature environment, was the tenth of its kind in the country. It was cooperatively purchased by Illinois Tech's Electrical Engineering department and a ten Midwest power companies for $80,000 in 1944. Photographer unknown. Date of photograph is unknown. Date listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: W.C. Jacobs and J.M. Brager of Consumer Powers Company with A-C Network Calculator, Illinois Institute of Technology, 1951
Date: 1951-08
Description: W.C Jacobs (left) and J. M. Brager (right) of Consumers Power Company, Jackson, Michigan, making adjustments on Illinois Institute of...
Show moreW.C Jacobs (left) and J. M. Brager (right) of Consumers Power Company, Jackson, Michigan, making adjustments on Illinois Institute of Technology's A-C Network Calculator during a study on the calculator of the Consumers Power system. The A-C Calculator, used to test complex power systems in a controlled, miniature environment, was the tenth of its kind in the country. It was cooperatively purchased by Illinois Tech's Electrical Engineering department and a ten Midwest power companies for $80,000 in 1944. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Josephine Mehlberg, ca. 1960
Creator: Illinois Institute of Technology
Date: 1960-1969
Description: Photograph of Professor Josephine Mehlberg teaching a mathematics class. Photographer was possibly Dan Ryan. Date of photograph is unknown....
Show morePhotograph of Professor Josephine Mehlberg teaching a mathematics class. Photographer was possibly Dan Ryan. Date of photograph is unknown. Date range listed is approximate.
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Collection: Dan Ryan collection, 1954-1980

Title: Decorative Thanksgiving table setting with taxidermied turkey, Illinois Institute of Technology, ca. 1970s
Creator: Illinois Institute of Technology
Date: 1970-1979
Description: Photograph of a decorative Thanksgiving display in an unknown location on the Illinois Tech campus. Date of photograph is unknown. Date range...
Show morePhotograph of a decorative Thanksgiving display in an unknown location on the Illinois Tech campus. Date of photograph is unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Costume Design course, Illinois Institute of Technology, ca. 1940s
Creator: Illinois Institute of Technology
Date: 1940-1949
Description: Photograph of a model and students in a costume design class. Date of photograph is unknown. Date range listed is approximate.
Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Picturephone equipment, 1973
Date: 1973
Description: Photograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's...
Show morePhotograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's Picturephone classes, the first in the country, debuted in 1974, offered to Bell employees in downtown Chicago and Oakbrook. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Demonstration of the Picturephone, 1973
Date: 1973
Description: Photograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's...
Show morePhotograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's Picturephone classes, the first in the country, debuted in 1974, offered to Bell employees in downtown Chicago and Oakbrook. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Classroom use of the Picturephone, 1973
Date: 1973
Description: Photograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's...
Show morePhotograph of the Western Electric Picturephone used by IIT's Evening Division in interactive distance learning classes. Illinois Tech's Picturephone classes, the first in the country, debuted in 1974, offered to Bell employees in downtown Chicago and Oakbrook. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: A-C Network Calculator, inside mechanics, Illinois Institute of Technology, Chicago, Illinois, 1945
Date: 1945
Description: Photograph of some of the inner mechanics of Illinois Institute of Technology's A-C Network Calculator. The A-C Calculator, used to test...
Show morePhotograph of some of the inner mechanics of Illinois Institute of Technology's A-C Network Calculator. The A-C Calculator, used to test complex power systems in a controlled, miniature environment, was the tenth of its kind in the country. It was cooperatively purchased by Illinois Tech's Electrical Engineering department and a ten Midwest power companies for $80,000 in 1944.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Navy V-12 unit on parade grounds of IIT campus during "Junior Week," Illinois Institute of Technology, Chicago, Illinois, 1944
Creator: Loop Photo Service
Date: 1944
Description: Photograph of uniformed students from Illinois Institute of Technology's V-12 Navy College Training Program during the Naval Review during ...
Show morePhotograph of uniformed students from Illinois Institute of Technology's V-12 Navy College Training Program during the Naval Review during "Junior Week," spring 1944.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Navy training in Alumni Memorial Hall, Illinois Institute of Technology, Chicago, Illinois, 1947
Date: 1947
Description: Photograph of an instructor and students from Illinois Institute of Technology's Naval Reserve Officers Training Corps (NROTC) Program in...
Show morePhotograph of an instructor and students from Illinois Institute of Technology's Naval Reserve Officers Training Corps (NROTC) Program in Alumni Hall. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Riverside Is installation view, Illinois Institute of Technology, Chicago, Illinois, 1971
Date: 1971
Description: Photograph of Riverview Is, an "environmental sculpture" installed by artist Phyllis Freeman in the Hermann Hall ballroom in the first two...
Show morePhotograph of Riverview Is, an "environmental sculpture" installed by artist Phyllis Freeman in the Hermann Hall ballroom in the first two weeks of March, 1971. Riverview Is recreated visuals from Chicago's Riverview Amusement Park, including the famous entrance to Alladin's Castle seen in the photograph. Photographer unknown.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: Josephine Mehlberg, ca. 1960
Creator: Illinois Institute of Technology
Date: 1960-1969
Description: Photograph of Professor Josephine Mehlberg teaching a mathematics class. Photographer was possibly Dan Ryan. Date of photograph is unknown....
Show morePhotograph of Professor Josephine Mehlberg teaching a mathematics class. Photographer was possibly Dan Ryan. Date of photograph is unknown. Date range listed is approximate.
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Collection: Dan Ryan collection, 1954-1980

Title: Dr. Rollin Dix and UNIVAC computer, Illinois Institute of Technology, Chicago, Illinois, ca.1970s
Creator: Commess, Herb
Date: 1969-1979
Description: Photograph of Dr. Rollin Dix with a UNIVAC computer (likely the UNIVAC 1108 Model II). Dr. Dix joined the IIT faculty in 1964, and retired in...
Show morePhotograph of Dr. Rollin Dix with a UNIVAC computer (likely the UNIVAC 1108 Model II). Dr. Dix joined the IIT faculty in 1964, and retired in 2004. Date unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: To Hell and Back
Creator: Sessions, Richard
Date: 2011
Description: Richard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student...
Show moreRichard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student under Frederick Sommer between 1957 and 1958. Included are Sessions' three photographs inspired by Sommer: "There ARE angels in America," "To Hell and Back," and "Breaking Up."
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Collection: Institute of Design Photography Oral History Project, 2011

Title: Breaking Up
Creator: Sessions, Richard
Date: 2011
Description: Richard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student...
Show moreRichard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student under Frederick Sommer between 1957 and 1958. Included are Sessions' three photographs inspired by Sommer: "There ARE angels in America," "To Hell and Back," and "Breaking Up."
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Collection: Institute of Design Photography Oral History Project, 2011

Title: Chuck Owen and unidentified Institute of Design professor at a computer, Illinois Institute of Technology, Chicago, Illinois, ca. 1979-1987
Date: 1979-1987
Description: From attached caption: "Professors at IIT's Institute of Design are advancing the state of the art in computer-aided design." Chuck Owen is at...
Show moreFrom attached caption: "Professors at IIT's Institute of Design are advancing the state of the art in computer-aided design." Chuck Owen is at right. This image was possibly included in a university viewbook. Photographer unknown. Date of photograph is unknown. Date range listed is approximate.
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Collection: Office of Communications and Marketing photographs, 1905-1999

Title: There ARE angels in America
Creator: Sessions, Richard
Date: 2011
Description: Richard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student...
Show moreRichard Sessions, who received an MS in Design in 1960 from the Institute of Design, provides a written account of his experience as a student under Frederick Sommer between 1957 and 1958. Included are Sessions' three photographs inspired by Sommer: "There ARE angels in America," "To Hell and Back," and "Breaking Up."
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Collection: Institute of Design Photography Oral History Project, 2011

Title: EXPERIMENTAL AND STRUCTURAL STUDIES OF FDA APPROVED EXON SKIPPING TREATMENT DRUGS
Creator: Zhang, Jingwen
Date: 2021
Description: DMD is an X-chromosome related genetic disease caused by loss of dystrophin protein expression, and which impacts 1 in 5000 boys born in the...
Show moreDMD is an X-chromosome related genetic disease caused by loss of dystrophin protein expression, and which impacts 1 in 5000 boys born in the world. The usual cause of this at the genetic level is a frame shift due to internal deletions of one or more exons that results in a change of the reading frame. This results in loss of expression of the protein encoded by this gene, dystrophin, which in turn leads to the disease phenotype. Exon skipping is a therapy for DMD which restores dystrophin pre-mRNA reading frame to produce a modified dystrophin. This is done by antisense oligonucleotides, AONs, which disturb the process of exon splicing and exclude targeted exons near the patient’s defect which restore the correct reading frame in the pre-mRNA transcript. In 2016, the first AON was approved for clinical use targeting exon 51, called eteplirsen. This provided the first disease modifying therapy for DMD, but it was only relevant to ~6% of patients who had defects that were correctable by skipping this specific exon. In 2020 two more AONs targeting exon 53 were developed, viltolarsen and golodirsen, providing benefit to an additional 5% of patients, and in 2021 casimersen targeting exon 45 was approved.However, this raises an interesting issue, in that for some patients, with an exon 52 deletion, skipping exon 51 or skipping exon 53 could both restore the reading frame. Which approved exon skipping treatment is better and the differences between them are still unknown. This is the aim of this study: to help patients figure out which AON can have a consequence of less long-term health problems like cardiomyopathy and longer life and get more precise treatment. We selected three exon skipped edits – two that represent exon 53 skipping repair of an underlying Δe52 defect and one targeting exon 51 skipping repair of a Δe52 defect. We then used a panel of biophysical and biochemical including dynamic light scattering, circular dichroism Spectroscopy, thermal denaturation, and protease K challenge to investigate the biophysical characteristics of these different exon skipped edits. From our results we found that Δe51-52 has the more structure (i.e., is less perturbed), compared to e52-53, as assessed by CD or by proteinase K challenge, but it also has lower thermal stability, with a low Tm=48C transition that begins to unfold at the physiological relevant temperature of 37C. On the other hand, e52-53 has less helical structure, but what structure did form had unfolding transitions in the normal range for wild type STRs, Tm> 60C; but this edit also had more non-helical structure. So, the total experimental results of these three edits are very complex, which may be due to the fact that these edits span the normally unfolded H3 region.
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