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Title
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Mold Report - IIT Tower - 2017
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Date
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2017,
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Description
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STAT Analysis received 5 samples for the referenced project on 2/20/2017 10:44:00 AM. The analytical results are presented in the following...
Show moreSTAT Analysis received 5 samples for the referenced project on 2/20/2017 10:44:00 AM. The analytical results are presented in the following report.
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Collection
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IIT Mold Reports
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Title
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Mold Report - Tech South - 2017
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Date
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2017,
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Description
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Pepper Environmental Technologies, Inc. conducted a mold air sampling study at Illinois Institute of Technology, Technology South, 3440 S....
Show morePepper Environmental Technologies, Inc. conducted a mold air sampling study at Illinois Institute of Technology, Technology South, 3440 S. State St., Chicago, Illinois. The survey was performed on April 26, 2017 in response to a request by Matt Cusack, Maintenance Supervisor, Facilities Department. Mold air samples were collected outdoors, and second floor.
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Collection
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IIT Mold Reports
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Title
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Controlling biofilms using synthetic biology approaches
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Date
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2020
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Description
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Bacterial biofilms are formed by the complex but ordered regulation of intra- or inter-cellular communication,...
Show moreBacterial biofilms are formed by the complex but ordered regulation of intra- or inter-cellular communication,
environmentally responsive gene expression, and secretion of extracellular polymeric substances. Given the
robust nature of bio?lms due to the non-growing nature of bio?lm bacteria and the physical barrier provided by
the extracellular matrix, eradicating bio?lms is a very di?cult task to accomplish with conventional antibiotic
or disinfectant treatments. Synthetic biology holds substantial promise for controlling bio?lms by improving and
expanding existing biological tools, introducing novel functions to the system, and re-conceptualizing gene
regulation. This review summarizes synthetic biology approaches used to eradicate bio?lms via protein
engineering of bio?lm-related enzymes, utilization of synthetic genetic circuits, and the development of
functional living agents. Synthetic biology also enables bene?cial applications of bio?lms through the
production of biomaterials and patterning bio?lms with speci?c temporal and spatial structures. Advances in
synthetic biology will add novel bio?lm functionalities for future therapeutic, biomanufacturing, and
environmental applications.
Sponsorship: NIH-R15AI130988, NSF CBET-1917130
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Title
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Incorporation of non-standard amino acids into proteins: challenges, recent achievements, and emerging
applications
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Date
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2019
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Description
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The natural genetic code only allows for 20 standard amino acids in protein translation, but genetic code...
Show moreThe natural genetic code only allows for 20 standard amino acids in protein translation, but genetic code
reprogramming enables the incorporation of non-standard amino acids (NSAAs). Proteins containing NSAAs provide
enhanced or novel properties and open diverse applications. With increased attention to the recent advancements
in synthetic biology, various improved and novel methods have been developed to incorporate single and multiple
distinct NSAAs into proteins. However, various challenges remain in regard to NSAA incorporation, such as low
yield and misincorporation. In this review, we summarize the recent efforts to improve NSAA incorporation by
utilizing orthogonal translational system optimization, cell-free protein synthesis, genomically recoded
organisms, artificial codon boxes, quadruplet codons, and orthogonal ribosomes, before closing with a discussion
of the emerging applications of NSAA incorporation.
Sponsorship: NIH R15AI130988
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Title
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Assessing Graduate Student Progress in Engineering Ethics
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Creator
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Davis, Michael, Feinerman, Alan
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Date
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2010-11-10, 2011
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Publisher
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Springer
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Description
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Under a grant from the National Science Foundation, the authors (and others) undertook to integrate ethics into...
Show moreUnder a grant from the National Science Foundation, the authors (and others) undertook to integrate ethics into
graduate engineering classes at three universities—and to assess success in a way allowing comparison across classes
(and institutions). This paper describes the attempt to carry out that assessment. Standard methods of assessment
turned out to demand too much class time. Under pressure from instructors, the authors developed an alternative
method that is both specific in content to individual classes and allows comparison across classes. Results are
statistically significant for ethical sensitivity and knowledge. They show measurable improvement in a single
semester.
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Title
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Recording Apparatus
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Creator
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Lang, Albert P.
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Date
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1962-09-11
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Description
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Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
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Title
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X-Ray Source
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Creator
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Reiffel, Leonard
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Date
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1957-06-25
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Description
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Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
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Title
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Magnetic Recorder
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Creator
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Camras, Marvin
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Date
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1958-10-21
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Description
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Sponsorship: Armour Research Foundation of Illinois Institute of Technology
United States Patent
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Title
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Doing physics : a festschrift for Thomas Erber
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Date
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2010, 2010
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Publisher
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IIT Press, Chicago, IL
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Description
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Doing Physics is a festschrift (collection of articles, essays, and rememberances) published in honor of Illinois Tech Physics professor...
Show moreDoing Physics is a festschrift (collection of articles, essays, and rememberances) published in honor of Illinois Tech Physics professor Thomas Erber's 80th birthday. Selections were authored by Erber's colleagues, former stduents, and fellow scholars. This book was released in print form, this file was the original pdf assembled by editor Porter Johnson and submitted for printing with the front and rear covers added.
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Title
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Optimizing Cell-Free Protein Synthesis for Increased Yield and Activity of Colicins
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Date
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2019,
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Publisher
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MDPI
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Description
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Colicins are antimicrobial proteins produced by Escherichia coli that hold great promise as viable complements...
Show moreColicins are antimicrobial proteins produced by Escherichia coli that hold great promise as viable complements
or alternatives to antibiotics. Cell-free protein synthesis (CFPS) is a useful production platform for toxic
proteins because it eliminates the need to maintain cell viability, a common problem in cell-based production.
Previously, we demonstrated that colicins produced by CFPS based on crude Escherichia coli lysates are e?ective
in eradicating antibiotic-tolerant bacteria known as persisters. However, we also found that some colicins have
poor solubility or low cell-killing activity. In this study, we improved the solubility of colicin M from 16% to
nearly 100% by producing it in chaperone-enriched E. coli extracts, resulting in enhanced cell-killing activity.
We also improved the cytotoxicity of colicin E3 by adding or co-expressing the E3 immunity protein during the
CFPS reaction, suggesting that the E3 immunity protein enhances colicin E3 activity in addition to protecting
the host strain. Finally, we con?rmed our previous ?nding that active colicins can be rapidly synthesized by
observing colicin E1 production over time in CFPS. Within three hours of CFPS incubation, colicin E1 reached its
maximum production yield and maintained high cytotoxicity during longer incubations up to 20 h. Taken together,
our ?ndings indicate that colicin production can be easily optimized for improved solubility and activity using
the CFPS platform.
Sponsorship: NIH R15AI130988
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Title
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German Spritzdekor Ceramics, 1928-1936: A Degenerate Art
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Date
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2018
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Publisher
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IIT Press
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Description
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An exhibition catalog for an exhibit housed in Galvin Library's Kemper Gallery from April to Septmeber, 2017. The exhibition was comprised of...
Show moreAn exhibition catalog for an exhibit housed in Galvin Library's Kemper Gallery from April to Septmeber, 2017. The exhibition was comprised of German airbrushed ceramics from the collection of Maral and Rolf Achilles. Ghazal Hashemi designed the Spritzdekor web site and this pdf catalog. All photographs are by Allen Bourgeois.
Sponsorship: Funding for this catalog was provided by grants from the Walter and Karla Goldschmidt Foundation and Richard H. Driehaus.
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Title
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Estimation for Dyadic-Dependent Exponential Random Graph Models
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Date
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2014, 2014-04-30
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Description
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Graphs are the primary mathematical representation for networks, with nodes or vertices corresponding to units (e.g., individuals) and edges...
Show moreGraphs are the primary mathematical representation for networks, with nodes or vertices corresponding to units (e.g., individuals) and edges corresponding to relationships. Exponential Random Graph Models (ERGMs) are widely used for describing network data because of their simple structure as an exponential function of a sum of parameters multiplied by their corresponding sufficient statistics. As with other exponential family settings the key computational difficulty is determining the normalizing constant for the likelihood function, a quantity that depends only on the data. In ERGMs for network data, the normalizing constant in the model often makes the parameter estimation intractable for large graphs, when the model involves dependence among dyads in the graph. One way to deal with this problem is to approximate the likelihood function by something tractable, e.g., by using the method of pseudo-likelihood estimation suggested in the early literature. In this paper, we describe the family of ERGMs and explain the increasing complexity that arises from imposing different edge dependence and homogeneous parameter assumptions. We then compare maximum likelihood (ML) and maximum pseudo-likelihood (MPL) estimation schemes with respect to existence and related degeneracy properties for ERGMs involving dependencies among dyads.
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Collection
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Journal of Algebraic Statistics
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Title
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Generic Identification of Binary-Valued Hidden Markov Processes
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Date
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2014, 2014-04-30
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Description
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The generic identification problem is to decide whether a stochastic process (X_t) is a hidden Markov process and if yes to infer its...
Show moreThe generic identification problem is to decide whether a stochastic process (X_t) is a hidden Markov process and if yes to infer its parameters for all but a subset of parametrizations that form a lower-dimensional subvariety in parameter space. Partial answers so far available depend on extra assumptions on the processes, which are usually centered around stationarity. Here we present a general solution for binary-valued hidden Markov processes. Our approach is rooted in algebraic statistics hence it is geometric in nature. We find that the algebraic varieties associated with the probability distributions of binary-valued hidden Markov processes are zero sets of determinantal equations which draws a connection to well-studied objects from algebra. As a consequence, our solution allows for algorithmic implementation based on elementary (linear) algebraic routines.
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Collection
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Journal of Algebraic Statistics
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