Epilepsy is the most common neurological disorder worldwide with a heterogeneous range of negative symptoms. Current treatments for epilepsy... Show moreEpilepsy is the most common neurological disorder worldwide with a heterogeneous range of negative symptoms. Current treatments for epilepsy have side effects that can negatively impact the quality of a person’s life. Alternative treatments are being explored, including marijuana. This study aimed to understand marijuana use in adults with epilepsy across U.S. states. Rates of use, preferred method of use, and reasons to use and not use marijuana were examined. Additionally, levels of comfort discussing marijuana compared to other treatment options and with different types of providers were explored. Lastly, this was one of the first studies to examine the relationship between quality of life (QOL) and marijuana use for people with epilepsy. Participants included 128 individuals with epilepsy from 26 states, with non-legal states having significantly fewer people who reported using marijuana. Smoking was reported as the primary method of use, knowing someone else that uses as their primary reason for using, and health concerns as the primary reason not to use. There was no difference in level of comfort discussing marijuana compared to other treatments, and participants reported feeling most comfortable discussing marijuana with neurologists compared to other providers. Finally, total QOLIE-31 and the social functioning subscale were significantly lower among marijuana users; however, this difference did not remain when anxiety was entered as a covariate. In fact, the relationship between anxiety and QOL was significant, with anxiety accounting for η2 = .12 to η2 = .57 of the variance in QOLIE-31 subscale scores, controlling for marijuana use. Findings from this study further the understanding of marijuana use by people with epilepsy in the United States. Show less
