Search results

(1 - 2 of 2)
THE RELATIONSHIPS OF BIOLOGICAL, PSYCHOLOGICAL, AND SOCIAL FACTORS TO PERCEIVED SEIZURE SEVERITY IN INDIVIDUALS WITH TEMPORAL LOBE EPILEPSY
Title
THE RELATIONSHIPS OF BIOLOGICAL, PSYCHOLOGICAL, AND SOCIAL FACTORS TO PERCEIVED SEIZURE SEVERITY IN INDIVIDUALS WITH TEMPORAL LOBE EPILEPSY
Creator
Fong, Wing Man
Date
2012-12-17, 2012-12
Description
Epilepsy is a chronic neurological condition that can cause negative consequences in all areas of life for people with the condition. Research...
Show moreEpilepsy is a chronic neurological condition that can cause negative consequences in all areas of life for people with the condition. Research evidence has led to the goal of treatment to gradually shift from targeting only reducing the frequency of seizures to decreasing individual’s perception of seizure severity. While several studies have suggested that psychological and social factors, in addition to epilepsy-related biological factors, can also impact seizure severity perception, this area has received much less attention in relation to individuals’ perception of seizure severity. Therefore, this study examined individuals’ perception of seizure severity using a biopsychosocial framework which takes into account biological, psychological, and social factors to develop a comprehensive understanding about the perception of seizure severity. 57 individuals from a neurology clinic at a tertiary medical center with a primary diagnosis of localization-related temporal lobe epilepsy participated in this study. They were interviewed for demographic information and were assessed using Quality of Life in Epilepsy-89, Beck Depression Inventory, Stressful Life Events Scale, and Liverpool Seizure Severity Scale. A Multiple regression analysis indicated that the number of antiepileptic drugs, perceived memory function, the number of stressful life events, and social support were all significant predictors of perceived seizure severity. The current findings supported a biopsychosocial approach in understanding the perception of seizure severity among people with epilepsy. Clinical implications of these findings are discussed.
M.S. in Psychology, December 2012
Show less
COGNITIVE IMPAIRMENT, DEPRESSION, AND INFLAMMATION IN OLDER HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS
Title
COGNITIVE IMPAIRMENT, DEPRESSION, AND INFLAMMATION IN OLDER HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS
Creator
Fong, Wing Man
Date
2015, 2015-07
Description
Cancer is a common disease that increases in prevalence with age; it predominantly affects individuals over the age of 55. Cancer can be...
Show moreCancer is a common disease that increases in prevalence with age; it predominantly affects individuals over the age of 55. Cancer can be associated with a number of health complications due to the disease itself and/or its treatments such as higher risk of infection, anemia, fatigue, and cognitive dysfunction. Risks of developing these complications increase with age. Despite the increased vulnerability among older individuals, the existing literature and clinical trials show a disproportionately low enrollment rate for this population. This study aimed to provide to a mechanism-based understanding of cognitive impairment in older patients with hematologic malignancy who were scheduled to undergo hematopoietic stem cell transplantation (HSCT). Emerging evidence suggests that a significant portion of older persons with cancer demonstrate cognitive impairment prior to HSCT, and that cognitive deficits prior to HSCT are related to post-transplant complications. Hence, the goals of the study were to characterize cognitive impairment in older cancer patients prior to HSCT, and to examine the relations between cognitive impairment, depression, and inflammation. Sixty-one patients with hematologic malignancy participated in the current study and were administered a comprehensive neuropsychological assessment. Results showed that 50% of the sample was impaired on verbal memory. Correlation analyses revealed a significant association between depression and attention, with inflammation found to be a non-significant mediator. Possible alternative explanations with implications for future research and limitations of the study were discussed.
Ph.D. in Psychology, July 2015
Show less