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Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
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Title: Control of grade transitions in distributed chemical reactor networks - An agent-based approach
Creator: Tetiker, M. Derya, Artel, Arsun, Teymour, Fouad, Cinar, Ali
Date: 2008-09-26
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Description: Supervision of distributed manufacturing processes producing different grades of a product requires intelligent reconfiguration strategies...
Show moreSupervision of distributed manufacturing processes producing different grades of a product requires intelligent reconfiguration strategies during grade transition phases to minimize off-spec production. Agent-based approaches are ideal for such problems and they provide flexible, robust, and emergent solutions during dynamically changing process conditions. Three different multi-layered multi-agent, frameworks are proposed for the supervision of grade transitions in autocatalytic reactor networks. The first framework is the centralized framework and it is useful for small-scale grade transitions where only a small region of the network needs to be reconfigured. Alternatively, the other two frameworks use a decentralized approach. The first decentralized framework implements genetic algorithms and the second one uses self-organizing heuristics and auctions for large-scale grade transitions. The case studies demonstrate that as the complexity of the reconfiguration problem increases, decentralized solutions perform more efficiently.
Endnote format citation for DOI:10.1016/j.compchemeng.2008.02.008
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Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Adaptive control strategy for regulation of blood glucose levels in patients with type 1 diabetes
Creator: Eren-oruklu, Meriyan, Cinar, Ali, Quinn, Lauretta, Smith, Donald
Date: 2009-09
Publisher: ELSEVIER SCI LTD
Description: Current insulin therapy for patients with type 1 diabetes often results in high variability in blood glucose concentrations and may cause hype...
Show moreCurrent insulin therapy for patients with type 1 diabetes often results in high variability in blood glucose concentrations and may cause hype rglycemic/hypoglycemic episodes. Closing the glucose control loop with a fully automated electro-mechanical pancreas will improve the quality of life for insulin-dependent patients. An adaptive control algorithm is proposed to keep glucose concentrations within normoglycemic range and dynamically respond to glycemic challenges. A model-based control strategy is used to calculate the required insulin infusion rate, while the model parameters are recursively tuned. The algorithm handles delays associated with insulin absorption, time-lag between subcutaneous and blood glucose concentrations, and variations in inter/intra-subject glucose-insulin dynamics. Simulation results for simultaneous meat and physiological disturbances are demonstrated for subcutaneous insulin infusion.
Endnote format citation for DOI:10.1016/j.jprocont.2009.04.004
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Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Automatic Insulin Pumps Using Recursive Multivariable Models and Adaptive Control Algorithms
Creator: Cinar, Ali, Oruklu, Meriyan
Date: 2014-04-09, 2014-04-08
Description: A method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a...
Show moreA method and device for monitoring or treating patient glucose levels. The device includes a glucose sensor for measuring a glucose level of a patient, a physiological status monitoring system for measuring at least one physical or metabolic variable of the patient, and an automatic controller in communication with the glucose sensor and the physiological status monitoring system. The controller includes a prediction module for automatically predicting a future glucose level using data measured by the glucose sensor and the physiological sensor.
Sponsorship: Illinois Institute of Technology
United States Patent
Show less

Title: Effect of Asymmetric Manipulations in Autocatalytic Networks
Creator: Balasubramanian, Sukanya, Cinar, Ali, Teymour, Fouad
Date: 2010-06-02
Publisher: AMER CHEMICAL SOC
Description: In this paper, we show that heterogeneous networks can be configured and reconfigured to operate in flexible spatial patterns The concept is...
Show moreIn this paper, we show that heterogeneous networks can be configured and reconfigured to operate in flexible spatial patterns The concept is demonstrated by using a square grid of continuous stirred tank reactors with nearest neighbor interactions and hosting multiple cubic autocatalytic species Asymmetry is introduced in the system by allowing for different feed flow rates in the reactors. A heterogeneous system offers expanded phase space, improved stability. and coexistence characteristics The advantages of asymmetry are studied using bifurcation diagrams, continuation studies. and dynamics
Endnote format citation for DOI:10.1021/ie901096v
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