A method and system for sensing or characterizing a biomarker, such as a proteolytic enzyme or nucleic acid. The system comprises a nanopore... Show moreA method and system for sensing or characterizing a biomarker, such as a proteolytic enzyme or nucleic acid. The system comprises a nanopore sensor to determine a current modulation of a sample including a biomarker, and a predetermined substrate or nucleic acid probe current modulation signature for comparison to a current signature from the nanopore sensor. The nanopore sensor includes a nanopore membrane between two fluid compartments, and a power supply in electrical contact with the membrane to provide an electric potential difference between the fluid compartments. A detector is used to detect an electrical current through the nanopore as the polypeptide substrate, or components thereof, transits the nanopore under an applied electric potential difference between the first and second fluid compartments. The result is a rapid, label-free method for the sensitive and accurate measurement of biomarker activity by real-time monitoring of the ionic current modulations arising from the substrate peptide-protease interactions or nucleic acid hybridization in the nanopore. Sponsorship: Illinois Institute of Technology United States Patent Show less
Methods and apparatus for treating waste with radio frequency include a wall defining a radio frequency treatment chamber through which waste... Show moreMethods and apparatus for treating waste with radio frequency include a wall defining a radio frequency treatment chamber through which waste may be passed. A source of radio frequency energy energizes the radio frequency treatment chamber to heat the waste and drive off vapors therefrom leaving solid residue to be disposed of. A guard heater and/or insulation maintains the wall at substantially the same temperature as the waste being heated by the radio frequency to prevent vapors from condensing on the waste. Sponsorship: IIT Research Institute United States Patent Show less
A method and apparatus are provided for distinguishing microscopic size, elongated fiber-like particles from cubically shaped, irregularly... Show moreA method and apparatus are provided for distinguishing microscopic size, elongated fiber-like particles from cubically shaped, irregularly shaped, or spherically shaped particles in a mixture suspended in an electrically conducting liquid medium and for counting the fiber-like particles. In accordance with the method, an electrical zone sensing apparatus is provided with a screen means having microscopic openings therein of predetermined size to filter from the suspension particles having an effective area larger than the size of screen openings. Particles passing through the screen and through the sensing aperture of the zone sensing apparatus are separately sized by volume characteristics of electrical signals generated. The electrical signals having predetermined volume characteristics associated with the maximum spherical particles for passing through the screen openings are counted as non-fiber particles; whereas signals having larger volume characteristics are separately counted and designated as fibers. By the use of screens of successively smaller sizes, the larger particles including fibers having larger transverse cross sections may be successively filtered from the suspension and from reaching the sensing aperture. Therefore, smaller fibers having smaller cross-sectional area may be distinguished from particles having diameters approximating that of the smaller screen size openings. Sponsorship: IIT Research Institute United States Patent Show less
An apparatus for generating odor including a disk having a substrate with a dispersing material retaining at least one releasable aroma... Show moreAn apparatus for generating odor including a disk having a substrate with a dispersing material retaining at least one releasable aroma positioned with respect to the substrate. The dispersing material includes a structure, such as a plurality of openable pores, that is physically responsive to a stimulus such as heat or light. A device provides the stimulus to the dispersing material upon demand as a function of a signal, wherein the plurality of pores within the dispersing material are reversibly enlarged as a result of the stimulus. Sponsorship: Illinois Institute of Technology United States Patent Show less
A robotic cane may include a grip handle, a cane body extending from the grip handle at a first end, a motorized omni-directional wheel... Show moreA robotic cane may include a grip handle, a cane body extending from the grip handle at a first end, a motorized omni-directional wheel coupled to a second end of the cane body, a balance control sensor, and a controller module. The balance control sensor provides a balance signal corresponding to an orientation of the robotic cane. The controller module may receive the balance signal from the balance control sensor and calculate a balancing velocity of the motorized omni-directional wheel based at least in part on the balance signal and an inverted pendulum control algorithm. The controller module may further provide a drive signal to the motorized omni-directional wheel in accordance with the calculated balancing velocity. The calculated balancing velocity is a speed and direction of the motorized omni-directional wheel to retain the robotic cane in an substantially upright position. Sponsorship: Toyota Motor Engineering & Manufacturing North America, Inc. Sponsorship: Illinois Institute of Technology United States Patent Show less
The present invention is directed to a process for the conversion of waste plastics and scrap rubber to a high quality synthetic crude oil... Show moreThe present invention is directed to a process for the conversion of waste plastics and scrap rubber to a high quality synthetic crude oil which can be separated by fractionation into gasoline, diesel fuel and gas oils suitable as a feedstock to a catalytic cracker. The process generally includes the steps of heating the plastic scrap and scrap automotive tires in a hydrogen atmosphere at moderate temperatures and pressures. It has also been determined that the polymeric waste material must be present in combination with the scrap automotive tires to attain conversion of the scrap automotive tires to liquid hydrocarbon. Sponsorship: IIT Research Institute United States Patent Show less
