A method and system for sensing or characterizing a biomarker, such as a proteolytic enzyme or nucleic acid. The system comprises a nanopore... Show moreA method and system for sensing or characterizing a biomarker, such as a proteolytic enzyme or nucleic acid. The system comprises a nanopore sensor to determine a current modulation of a sample including a biomarker, and a predetermined substrate or nucleic acid probe current modulation signature for comparison to a current signature from the nanopore sensor. The nanopore sensor includes a nanopore membrane between two fluid compartments, and a power supply in electrical contact with the membrane to provide an electric potential difference between the fluid compartments. A detector is used to detect an electrical current through the nanopore as the polypeptide substrate, or components thereof, transits the nanopore under an applied electric potential difference between the first and second fluid compartments. The result is a rapid, label-free method for the sensitive and accurate measurement of biomarker activity by real-time monitoring of the ionic current modulations arising from the substrate peptide-protease interactions or nucleic acid hybridization in the nanopore. Sponsorship: Illinois Institute of Technology United States Patent Show less
This project is a focus on spatial flexibility. The idea is to generate housing components that focuses on flexibility in order to create... Show moreThis project is a focus on spatial flexibility. The idea is to generate housing components that focuses on flexibility in order to create space that is defined by the user. Show less
Methods and apparatus for treating waste with radio frequency include a wall defining a radio frequency treatment chamber through which waste... Show moreMethods and apparatus for treating waste with radio frequency include a wall defining a radio frequency treatment chamber through which waste may be passed. A source of radio frequency energy energizes the radio frequency treatment chamber to heat the waste and drive off vapors therefrom leaving solid residue to be disposed of. A guard heater and/or insulation maintains the wall at substantially the same temperature as the waste being heated by the radio frequency to prevent vapors from condensing on the waste. Sponsorship: IIT Research Institute United States Patent Show less
reexamination of centralized supportive housing in an urban context emphasizing the supportive characteristics of a productive green space.... Show morereexamination of centralized supportive housing in an urban context emphasizing the supportive characteristics of a productive green space. Other supportive elements at grade include culinary training, mixed use units, and transportation center. Show less
A method and apparatus are provided for distinguishing microscopic size, elongated fiber-like particles from cubically shaped, irregularly... Show moreA method and apparatus are provided for distinguishing microscopic size, elongated fiber-like particles from cubically shaped, irregularly shaped, or spherically shaped particles in a mixture suspended in an electrically conducting liquid medium and for counting the fiber-like particles. In accordance with the method, an electrical zone sensing apparatus is provided with a screen means having microscopic openings therein of predetermined size to filter from the suspension particles having an effective area larger than the size of screen openings. Particles passing through the screen and through the sensing aperture of the zone sensing apparatus are separately sized by volume characteristics of electrical signals generated. The electrical signals having predetermined volume characteristics associated with the maximum spherical particles for passing through the screen openings are counted as non-fiber particles; whereas signals having larger volume characteristics are separately counted and designated as fibers. By the use of screens of successively smaller sizes, the larger particles including fibers having larger transverse cross sections may be successively filtered from the suspension and from reaching the sensing aperture. Therefore, smaller fibers having smaller cross-sectional area may be distinguished from particles having diameters approximating that of the smaller screen size openings. Sponsorship: IIT Research Institute United States Patent Show less