creator Beissinger, Richard L. creator Wasan, Darsh T. creator Sehgal, Lakshman creator Rosen, Arthur L. A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsion while maintaining high yields and high oxygen exchange activity. A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute. Submitted by Aric Ahrens (ahrens@iit.edu) on 2011-12-08T21:49:23Z No. of bitstreams: 1 5217648.pdf: 314652 bytes, checksum: 18ba3c7d7926806e1dd1afd415a95b6a (MD5) Made available in DSpace on 2011-12-08T21:49:23Z (GMT). No. of bitstreams: 1 5217648.pdf: 314652 bytes, checksum: 18ba3c7d7926806e1dd1afd415a95b6a (MD5) Previous issue date: 1993-06-08 Illinois Institute of Technology Northfield Laboratories, Inc. 2009-05-11 1993-06-08 5,217,648 http://hdl.handle.net/10560/2403 en United States Patent Patent reformatted digital application/pdf No Copyright - United States http://rightsstatements.org/page/NoC-US/1.0/ Open Access