creator Klug, Allen creator Kuuspalu, Adam creator Smith, Adam creator Naveenan, Anju creator Sin, In Seok creator Sonoiki, Olufemi creator Wakeman, William Our team was asked to come up with an innovative and non-invasive means of extracting and measuring glucose levels in the body as well as administering insulin back into the body, also by non-invasive means. Our research lead us to several reports on the effectiveness of ultrasound in expanding pore opening diameters. We decided to approach the problem with a device that would administer ultrasonic vibration to the surface of the skin thus expanding the pore openings. Once expanded a combination of vacuum and reverse iontophoresis would then extract a small amount of interstitial fluid. The fluid would be measured for glucose concentration using impedance spectroscopy. Once a glucose concentration was found, a proper amount of insulin would then be administered back through the skin by means of pressure and iontophoresis. Our experiments were conducted on harvested porcine skin. Sonic vibration at or around 10kHz served as a substitute for ultrasound. Vacuum was administered to the surface of the skin after a set amount of time of sonic vibration. Although results at first seemed promising, further investigation into the behavior of harvested skin yielded that our results were not as they seemed. Impedance spectroscopy was explored by first trying to find the resonant frequency of glucose. Earlier attempts at this were unsuccessful do to frequency limitations of measuring devices. Our team learned of a device that could measure 10 times higher frequencies than what had previously been recorded, but unfortunately was unable to solidify a concrete resonant frequency for glucose. Submitted by Vishal Patel (vpatel87@iit.edu) on 2011-03-22T22:08:48Z No. of bitstreams: 6 Creating an Artificial Pancreas IPRO 308 Poster F08.pdf: 136529 bytes, checksum: 9bc84196c22bca8322360e49ba1a5e3f (MD5) Creating an Artificial Pancreas IPRO 308 MidTerm Presentation F08.pdf: 2378282 bytes, checksum: e02b17df3352535eafbf4628b52000dc (MD5) Creating an Artificial Pancreas IPRO 308 Final Report F08.pdf: 292199 bytes, checksum: 3b653a3d3cc47a4470a658c1afed362a (MD5) Creating an Artificial Pancreas IPRO 308 Final Presentation F08.pdf: 1165111 bytes, checksum: 36c71d5513b3236cd92c8ede0d55a32e (MD5) Creating an Artificial Pancreas IPRO 308 Ethics F08.pdf: 68199 bytes, checksum: eb9e8ac4e7c0c5c3febaae90b578bf59 (MD5) Creating an Artificial Pancreas IPRO 308 Brochure F08.pdf: 66343 bytes, checksum: a2fe8e7a1913b037a55474e969d3c09c (MD5) Approved for entry into archive by Charles Uth(uth@iit.edu) on 2011-03-23T13:08:16Z (GMT) No. of bitstreams: 6 Creating an Artificial Pancreas IPRO 308 Poster F08.pdf: 136529 bytes, checksum: 9bc84196c22bca8322360e49ba1a5e3f (MD5) Creating an Artificial Pancreas IPRO 308 MidTerm Presentation F08.pdf: 2378282 bytes, checksum: e02b17df3352535eafbf4628b52000dc (MD5) Creating an Artificial Pancreas IPRO 308 Final Report F08.pdf: 292199 bytes, checksum: 3b653a3d3cc47a4470a658c1afed362a (MD5) Creating an Artificial Pancreas IPRO 308 Final Presentation F08.pdf: 1165111 bytes, checksum: 36c71d5513b3236cd92c8ede0d55a32e (MD5) Creating an Artificial Pancreas IPRO 308 Ethics F08.pdf: 68199 bytes, checksum: eb9e8ac4e7c0c5c3febaae90b578bf59 (MD5) Creating an Artificial Pancreas IPRO 308 Brochure F08.pdf: 66343 bytes, checksum: a2fe8e7a1913b037a55474e969d3c09c (MD5) Made available in DSpace on 2011-03-23T13:08:16Z (GMT). No. of bitstreams: 6 Creating an Artificial Pancreas IPRO 308 Poster F08.pdf: 136529 bytes, checksum: 9bc84196c22bca8322360e49ba1a5e3f (MD5) Creating an Artificial Pancreas IPRO 308 MidTerm Presentation F08.pdf: 2378282 bytes, checksum: e02b17df3352535eafbf4628b52000dc (MD5) Creating an Artificial Pancreas IPRO 308 Final Report F08.pdf: 292199 bytes, checksum: 3b653a3d3cc47a4470a658c1afed362a (MD5) Creating an Artificial Pancreas IPRO 308 Final Presentation F08.pdf: 1165111 bytes, checksum: 36c71d5513b3236cd92c8ede0d55a32e (MD5) Creating an Artificial Pancreas IPRO 308 Ethics F08.pdf: 68199 bytes, checksum: eb9e8ac4e7c0c5c3febaae90b578bf59 (MD5) Creating an Artificial Pancreas IPRO 308 Brochure F08.pdf: 66343 bytes, checksum: a2fe8e7a1913b037a55474e969d3c09c (MD5) Previous issue date: 2008-12 Deliverables 2008 2008-12 http://hdl.handle.net/10560/1636 en Emmanuel Opara Raymond DeBoth Project deliverable born digital application/pdf In Copyright http://rightsstatements.org/page/InC/1.0/ Open Access IPRO / Interprofessional Projects Program Illinois Institute of Technology Affiliated department