creator Geevarghese Alex, Peter 2023 Spring 2023 Thesis Illinois Institute of Technology BIOL / Biology advisor Edirisinghe, Indika Food science Halt™ Inflammation Lipopolysaccharide (LPS) Nuclear Factor Kappa B (NF-κB) PBMC Postprandial Inflammation en Our modern culture in our society is facing one of the biggest risks in health which is high-calorie diet-related postprandial inflammation. Chronic diseases may be caused if the energy-dense food is the choice meaning if it is uncontrolled, clinical studies have demonstrated this with the body's post-meal inflammatory response. We aimed to find the causes of postprandial inflammation in response to various dietary treatments and provide a model to demonstrate. We aimed to make use of in vivo and in vitro techniques and statistics to create a model. The created model would help us to design specific treatments to minimize inflammation with response to dietary. In addition to figuring out vital dietary additives, the model additionally facilitates the layout of individualized interventions to reduce inflammation, thereby improving long-time period health outcomes. We aim to understand the clinical observations of diet-induced postprandial inflammation on the molecular level. We desire to make contributions to reduce the impact of chronic inflammatory disorders that is associated with postprandial inflammation. born digital application/pdf In Copyright http://rightsstatements.org/page/InC/1.0/ Restricted Access http://hdl.handle.net/10560/islandora:1025230